FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0207, 277 aa
  1>>>pF1KE0207 277 - 277 aa - 277 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.3445+/-0.00032; mu= 4.7389+/- 0.020
 mean_var=259.5259+/-52.207, 0's: 0 Z-trim(125.1): 4  B-trim: 43 in 1/59
 Lambda= 0.079613
 statistics sampled from 47995 (47999) to 47995 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.842), E-opt: 0.2 (0.563), width:  16
 Scan time:  8.520

The best scores are:                                      opt bits E(85289)
NP_653169 (OMIM: 609865) type 1 phosphatidylinosit ( 277) 2020 244.0 2.4e-64
NP_001094284 (OMIM: 609865) type 1 phosphatidylino ( 284) 1996 241.2 1.6e-63
NP_061180 (OMIM: 609864) type 2 phosphatidylinosit ( 257)  955 121.6 1.5e-27
XP_011515454 (OMIM: 609864) PREDICTED: type 2 phos ( 189)  749 97.8 1.6e-20


>>NP_653169 (OMIM: 609865) type 1 phosphatidylinositol 4  (277 aa)
 initn: 2020 init1: 2020 opt: 2020  Z-score: 1276.3  bits: 244.0 E(85289): 2.4e-64
Smith-Waterman score: 2020; 99.6% identity (99.6% similar) in 277 aa overlap (1-277:1-277)

               10        20        30        40        50        60
pF1KE0 MAADGERSPLLSEPIDGGAGGNGLVGPGGSGAGPGGGLTPSAPPYGAAFPPFPEGHPAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 MAADGERSPLLSEPIDGGAGGNGLVGPGGSGAGPGGGLTPSAPPYGAAFPPFPEGHPAVL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 PGEDPPPYSPLTSPDSGSAPMITCRVCQSLINVEGKMHQHVVKCGVCNEATPIKNAPPGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 PGEDPPPYSPLTSPDSGSAPMITCRVCQSLINVEGKMHQHVVKCGVCNEATPIKNAPPGK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 KYVRCPCNCLLICKVTSQRIACPRPYCKRIINLGPVHPGPLSPEPQPMGVRVICGHCKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 KYVRCPCNCLLICKVTSQRIACPRPYCKRIINLGPVHPGPLSPEPQPMGVRVICGHCKNT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 FLWTEFTDRTLARCPHCRKVSSIGRRYTRKRCICCFLLGLLLAVTATGLAFGTWKHARRY
       ::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
NP_653 FLWTEFTDRTLARCPHCRKVSSIGRRYPRKRCICCFLLGLLLAVTATGLAFGTWKHARRY
              190       200       210       220       230       240

              250       260       270       
pF1KE0 GGIYAAWAFVILLAVLCLGRALYWACMKVSHPVQNFS
       :::::::::::::::::::::::::::::::::::::
NP_653 GGIYAAWAFVILLAVLCLGRALYWACMKVSHPVQNFS
              250       260       270       

>>NP_001094284 (OMIM: 609865) type 1 phosphatidylinosito  (284 aa)
 initn: 1701 init1: 1701 opt: 1996  Z-score: 1261.3  bits: 241.2 E(85289): 1.6e-63
Smith-Waterman score: 1996; 97.2% identity (97.2% similar) in 284 aa overlap (1-277:1-284)

               10        20        30        40               50   
pF1KE0 MAADGERSPLLSEPIDGGAGGNGLVGPGGSGAGPGGGLTPSAPPYGA-------AFPPFP
       :::::::::::::::::::::::::::::::::::::::::::::::       ::::::
NP_001 MAADGERSPLLSEPIDGGAGGNGLVGPGGSGAGPGGGLTPSAPPYGAGKHAPPQAFPPFP
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KE0 EGHPAVLPGEDPPPYSPLTSPDSGSAPMITCRVCQSLINVEGKMHQHVVKCGVCNEATPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGHPAVLPGEDPPPYSPLTSPDSGSAPMITCRVCQSLINVEGKMHQHVVKCGVCNEATPI
               70        80        90       100       110       120

           120       130       140       150       160       170   
pF1KE0 KNAPPGKKYVRCPCNCLLICKVTSQRIACPRPYCKRIINLGPVHPGPLSPEPQPMGVRVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNAPPGKKYVRCPCNCLLICKVTSQRIACPRPYCKRIINLGPVHPGPLSPEPQPMGVRVI
              130       140       150       160       170       180

           180       190       200       210       220       230   
pF1KE0 CGHCKNTFLWTEFTDRTLARCPHCRKVSSIGRRYTRKRCICCFLLGLLLAVTATGLAFGT
       :::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
NP_001 CGHCKNTFLWTEFTDRTLARCPHCRKVSSIGRRYPRKRCICCFLLGLLLAVTATGLAFGT
              190       200       210       220       230       240

           240       250       260       270       
pF1KE0 WKHARRYGGIYAAWAFVILLAVLCLGRALYWACMKVSHPVQNFS
       ::::::::::::::::::::::::::::::::::::::::::::
NP_001 WKHARRYGGIYAAWAFVILLAVLCLGRALYWACMKVSHPVQNFS
              250       260       270       280    

>>NP_061180 (OMIM: 609864) type 2 phosphatidylinositol 4  (257 aa)
 initn: 1070 init1: 555 opt: 955  Z-score: 615.6  bits: 121.6 E(85289): 1.5e-27
Smith-Waterman score: 996; 52.4% identity (72.0% similar) in 286 aa overlap (1-277:1-257)

                 10        20        30        40        50        
pF1KE0 MAADG--ERSPLLSEPIDGGAGGNGLVGPGGSGAGPGGGLTPSAPPYGAAFPPFPEGHPA
       :::::  :::::::                   :. .:..::.::::      . :. : 
NP_061 MAADGVDERSPLLS-------------------ASHSGNVTPTAPPY------LQESSPR
               10                           20              30     

       60        70        80        90       100       110        
pF1KE0 VLPGEDPPPYSPLTSPDSGSAPMITCRVCQSLINVEGKMHQHVVKCGVCNEATPIKNAPP
       .   : ::::. ..:::... :.:.:::::::::..::.::::::: :::::::::: : 
NP_061 A---ELPPPYTAIASPDASGIPVINCRVCQSLINLDGKLHQHVVKCTVCNEATPIKNPPT
             40        50        60        70        80        90  

      120       130       140       150           160         170  
pF1KE0 GKKYVRCPCNCLLICKVTSQRIACPRPYCKRIINLGPV----HPGPLSPE-P-QPMGVRV
       :::::::::::::::: ::.::.:::: :.::::::::    .  : .:  : :: :.::
NP_061 GKKYVRCPCNCLLICKDTSRRIGCPRPNCRRIINLGPVMLISEEQPAQPALPIQPEGTRV
            100       110       120       130       140       150  

            180       190       200       210        220       230 
pF1KE0 ICGHCKNTFLWTEFTDRTLARCPHCRKVSSIGRRYTRKRCICCFL-LGLLLAVTATGLAF
       .:::: ::::: :.   :::.::::.:.::.:    :.:: : .. .:..    ..::. 
NP_061 VCGHCGNTFLWMELRFNTLAKCPHCKKISSVGSALPRRRC-CAYITIGMICIFIGVGLTV
            160       170       180       190        200       210 

             240       250       260       270       
pF1KE0 GTWKHARRYGGIYAAWAFVILLAVLCLGRALYWACMKVSHPVQNFS
       ::   :::. . :..::.. ::...:: :: ::. ..::.: ..:.
NP_061 GTPDFARRFRATYVSWAIAYLLGLICLIRACYWGAIRVSYPEHSFA
             220       230       240       250       

>>XP_011515454 (OMIM: 609864) PREDICTED: type 2 phosphat  (189 aa)
 initn: 839 init1: 555 opt: 749  Z-score: 489.3  bits: 97.8 E(85289): 1.6e-20
Smith-Waterman score: 790; 57.9% identity (72.2% similar) in 209 aa overlap (1-201:1-181)

                 10        20        30        40        50        
pF1KE0 MAADG--ERSPLLSEPIDGGAGGNGLVGPGGSGAGPGGGLTPSAPPYGAAFPPFPEGHPA
       :::::  :::::::                   :. .:..::.::::      . :. : 
XP_011 MAADGVDERSPLLS-------------------ASHSGNVTPTAPPY------LQESSPR
               10                           20              30     

       60        70        80        90       100       110        
pF1KE0 VLPGEDPPPYSPLTSPDSGSAPMITCRVCQSLINVEGKMHQHVVKCGVCNEATPIKNAPP
       .   : ::::. ..:::... :.:.:::::::::..::.::::::: :::::::::: : 
XP_011 A---ELPPPYTAIASPDASGIPVINCRVCQSLINLDGKLHQHVVKCTVCNEATPIKNPPT
             40        50        60        70        80        90  

      120       130       140       150           160         170  
pF1KE0 GKKYVRCPCNCLLICKVTSQRIACPRPYCKRIINLGPV----HPGPLSPE-P-QPMGVRV
       :::::::::::::::: ::.::.:::: :.::::::::    .  : .:  : :: :.::
XP_011 GKKYVRCPCNCLLICKDTSRRIGCPRPNCRRIINLGPVMLISEEQPAQPALPIQPEGTRV
            100       110       120       130       140       150  

            180       190       200       210       220       230  
pF1KE0 ICGHCKNTFLWTEFTDRTLARCPHCRKVSSIGRRYTRKRCICCFLLGLLLAVTATGLAFG
       .:::: ::::: :.   :::.::::.:.:                               
XP_011 VCGHCGNTFLWMELRFNTLAKCPHCKKISLYMEKQSG                       
            160       170       180                                




277 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 21:15:16 2016 done: Thu Nov  3 21:15:17 2016
 Total Scan time:  8.520 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]