FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0217, 172 aa 1>>>pF1KE0217 172 - 172 aa - 172 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1861+/-0.000706; mu= 12.8071+/- 0.043 mean_var=58.3777+/-11.667, 0's: 0 Z-trim(108.8): 24 B-trim: 0 in 0/52 Lambda= 0.167861 statistics sampled from 10457 (10481) to 10457 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.322), width: 16 Scan time: 1.830 The best scores are: opt bits E(32554) CCDS1877.1 LGALSL gene_id:29094|Hs108|chr2 ( 172) 1166 290.1 4.4e-79 CCDS12521.1 LGALS4 gene_id:3960|Hs108|chr19 ( 323) 305 81.7 4.5e-16 CCDS1611.1 LGALS8 gene_id:3964|Hs108|chr1 ( 359) 304 81.5 5.8e-16 CCDS1612.1 LGALS8 gene_id:3964|Hs108|chr1 ( 317) 303 81.2 6.2e-16 CCDS32592.1 LGALS9 gene_id:3965|Hs108|chr17 ( 323) 301 80.8 8.8e-16 CCDS11222.1 LGALS9 gene_id:3965|Hs108|chr17 ( 355) 301 80.8 9.6e-16 CCDS42283.1 LGALS9B gene_id:284194|Hs108|chr17 ( 355) 295 79.3 2.6e-15 CCDS32587.1 LGALS9C gene_id:654346|Hs108|chr17 ( 356) 289 77.9 7.2e-15 >>CCDS1877.1 LGALSL gene_id:29094|Hs108|chr2 (172 aa) initn: 1166 init1: 1166 opt: 1166 Z-score: 1533.2 bits: 290.1 E(32554): 4.4e-79 Smith-Waterman score: 1166; 100.0% identity (100.0% similar) in 172 aa overlap (1-172:1-172) 10 20 30 40 50 60 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQSAIPYFPFIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 DLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQSAIPYFPFIP 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 DQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 DQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG 130 140 150 160 170 >>CCDS12521.1 LGALS4 gene_id:3960|Hs108|chr19 (323 aa) initn: 317 init1: 209 opt: 305 Z-score: 402.0 bits: 81.7 E(32554): 4.5e-16 Smith-Waterman score: 305; 31.8% identity (66.9% similar) in 154 aa overlap (17-169:170-319) 10 20 30 40 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSS-PVQADVYFPRLIVPFCGHIK :: ...:.: :.. ::. :... CCDS12 GDLQLQSINFIGGQPLRPQGPPMMPPYPGPGHCHQQLNSLPTMEGPPTFNPPVPYFGRLQ 140 150 160 170 180 190 50 60 70 80 90 100 pF1KE0 GGMRPGKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGE ::. . ... : : . .::::.. :.: .:.:.... . . ..::: ..: CCDS12 GGLTARRTIIIKGYVPPTGKSFAINFKVGSS----GDIALHINPRMGNGTVVRNSLLNGS 200 210 220 230 240 250 110 120 130 140 150 160 pF1KE0 RGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGD : :.. : . :: : : : . : : ::.:...:..:::: ::..... .::..:.:: CCDS12 WGSEEKKITHNPFGPGQFFDLSIRCGLDRFKVYANGQHLFDFAHRLSAFQRVDTLEIQGD 260 270 280 290 300 310 170 pF1KE0 LQITKLG . .. CCDS12 VTLSYVQI 320 >>CCDS1611.1 LGALS8 gene_id:3964|Hs108|chr1 (359 aa) initn: 353 init1: 191 opt: 304 Z-score: 400.0 bits: 81.5 E(32554): 5.8e-16 Smith-Waterman score: 304; 31.1% identity (64.1% similar) in 167 aa overlap (5-171:194-356) 10 20 30 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFP .: . .: :. .:..:. . . CCDS16 SLELTEISRENVPKSGTPQLPSNRGGDISKIAPRTVYTKSKDSTVNHTLTCTKIPPMNYV 170 180 190 200 210 220 40 50 60 70 80 90 pF1KE0 RLIVPFCGHIKGGMRPGKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDR .:: .... : ::. :.: : :. : .:: ..: : :. :.:..:. .. . CCDS16 SKRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSK----DIALHLNPRLNIK 230 240 250 260 270 100 110 120 130 140 150 pF1KE0 QLLRNSCISGERGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTL ..::: .. :::. : ::: : . :.. : :. .:.: :.: . ... ::.. : CCDS16 AFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKEL 280 290 300 310 320 330 160 170 pF1KE0 SAIDTIKINGDLQITKLG :.:::..::::... .. CCDS16 SSIDTLEINGDIHLLEVRSW 340 350 >>CCDS1612.1 LGALS8 gene_id:3964|Hs108|chr1 (317 aa) initn: 353 init1: 191 opt: 303 Z-score: 399.6 bits: 81.2 E(32554): 6.2e-16 Smith-Waterman score: 303; 35.5% identity (68.8% similar) in 138 aa overlap (34-171:181-314) 10 20 30 40 50 60 pF1KE0 SVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIVDLN :.: .:: .... : ::. :.: : :. : CCDS16 FSFSSDLQSTQASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNAN 160 170 180 190 200 210 70 80 90 100 110 120 pF1KE0 PESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQSAIPYFPFIPDQP .:: ..: : :.: .:..:. .. . ..::: .. :::. : ::: : . CCDS16 AKSFNVDLLAGKSKD----IALHLNPRLNIKAFVRNSFLQESWGEEERNITSFPFSPGMY 220 230 240 250 260 130 140 150 160 170 pF1KE0 FRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG :.. : :. .:.: :.: . ... ::.. ::.:::..::::... .. CCDS16 FEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW 270 280 290 300 310 >>CCDS32592.1 LGALS9 gene_id:3965|Hs108|chr17 (323 aa) initn: 363 init1: 188 opt: 301 Z-score: 396.8 bits: 80.8 E(32554): 8.8e-16 Smith-Waterman score: 301; 32.9% identity (66.4% similar) in 152 aa overlap (23-171:176-321) 10 20 30 40 50 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPR--LIVPFCGHIKGGMRP .:.:. ...:. .:: : ::. : CCDS32 SFQPPGVWPANPAPITQTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYP 150 160 170 180 190 200 60 70 80 90 100 110 pF1KE0 GKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQ .:..:. : : . . : :.: :. .:..:. : . ..::. :.. : :. CCDS32 SKSILLSGTVLPSAQRFHINLCSGNH------IAFHLNPRFDENAVVRNTQIDNSWGSEE 210 220 230 240 250 120 130 140 150 160 pF1KE0 SAIPY-FPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQIT ..: .::. : : : :::: ..: :::..::..:::...: .:. ....::.:.: CCDS32 RSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINRLEVGGDIQLT 260 270 280 290 300 310 170 pF1KE0 KLG .. CCDS32 HVQT 320 >>CCDS11222.1 LGALS9 gene_id:3965|Hs108|chr17 (355 aa) initn: 363 init1: 188 opt: 301 Z-score: 396.2 bits: 80.8 E(32554): 9.6e-16 Smith-Waterman score: 301; 32.9% identity (66.4% similar) in 152 aa overlap (23-171:208-353) 10 20 30 40 50 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPR--LIVPFCGHIKGGMRP .:.:. ...:. .:: : ::. : CCDS11 RQKPPGVWPANPAPITQTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYP 180 190 200 210 220 230 60 70 80 90 100 110 pF1KE0 GKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQ .:..:. : : . . : :.: :. .:..:. : . ..::. :.. : :. CCDS11 SKSILLSGTVLPSAQRFHINLCSGNH------IAFHLNPRFDENAVVRNTQIDNSWGSEE 240 250 260 270 280 290 120 130 140 150 160 pF1KE0 SAIPY-FPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQIT ..: .::. : : : :::: ..: :::..::..:::...: .:. ....::.:.: CCDS11 RSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINRLEVGGDIQLT 300 310 320 330 340 350 170 pF1KE0 KLG .. CCDS11 HVQT >>CCDS42283.1 LGALS9B gene_id:284194|Hs108|chr17 (355 aa) initn: 361 init1: 184 opt: 295 Z-score: 388.3 bits: 79.3 E(32554): 2.6e-15 Smith-Waterman score: 295; 31.6% identity (67.8% similar) in 152 aa overlap (23-171:208-353) 10 20 30 40 50 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPR--LIVPFCGHIKGGMRP .:.:. ...:. .:: : ::. : CCDS42 RQKPPSVRPANPAPITQTVIHTVQSASGQMFSTPAIPPMMYPHPAYPMPFITTIPGGLYP 180 190 200 210 220 230 60 70 80 90 100 110 pF1KE0 GKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQ .:.... : : . . : :.: :. :. .:.... : . ..::. :.. : :. CCDS42 SKSIILSGTVLPSAQRFHINL-CSGSH-----IAFHMNPRFDENAVVRNTQINNSWGSEE 240 250 260 270 280 290 120 130 140 150 160 pF1KE0 SAIPY-FPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQIT ..: .::. : : : :::: ..: :::...:..:::...: .:. ....::.:.: CCDS42 RSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHVFEYYHRLRNLPTINKLEVGGDIQLT 300 310 320 330 340 350 170 pF1KE0 KLG .. CCDS42 HVQT >>CCDS32587.1 LGALS9C gene_id:654346|Hs108|chr17 (356 aa) initn: 361 init1: 184 opt: 289 Z-score: 380.4 bits: 77.9 E(32554): 7.2e-15 Smith-Waterman score: 289; 33.1% identity (67.6% similar) in 139 aa overlap (34-171:222-354) 10 20 30 40 50 60 pF1KE0 SVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIVDLN : .:: : ::. :.:.... : : . CCDS32 ITQTVIHTVQSASGQMFSQTPAIPPMMYPHPAYPMPFITTIPGGLYPSKSIILSGTVLPS 200 210 220 230 240 250 70 80 90 100 110 120 pF1KE0 PESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQSAIPY-FPFIPDQ . : :.: :. :. .:.... : . ..::. :.. : :. ..: .::. : CCDS32 AQRFHINL-CSGSH-----IAFHMNPRFDENAVVRNTQINNSWGSEERSLPRKMPFVRGQ 260 270 280 290 300 130 140 150 160 170 pF1KE0 PFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG : : :::: ..: :::...:..:::...: .:. ....::.:.:.. CCDS32 SFSVWILCEAHCLKVAVDGQHVFEYYHRLRNLPTINKLEVGGDIQLTHVQT 310 320 330 340 350 172 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:53:21 2016 done: Thu Nov 3 20:53:21 2016 Total Scan time: 1.830 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]