FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0217, 172 aa 1>>>pF1KE0217 172 - 172 aa - 172 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8592+/-0.000323; mu= 14.7482+/- 0.020 mean_var=57.2436+/-11.445, 0's: 0 Z-trim(115.7): 40 B-trim: 1027 in 1/51 Lambda= 0.169516 statistics sampled from 26221 (26261) to 26221 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.308), width: 16 Scan time: 5.500 The best scores are: opt bits E(85289) XP_011525276 (OMIM: 602518) PREDICTED: galectin-4 ( 192) 305 82.3 4.8e-16 NP_006140 (OMIM: 602518) galectin-4 [Homo sapiens] ( 323) 305 82.4 7.4e-16 NP_963839 (OMIM: 606099) galectin-8 isoform a [Hom ( 359) 304 82.2 9.5e-16 NP_006490 (OMIM: 606099) galectin-8 isoform a [Hom ( 359) 304 82.2 9.5e-16 NP_963837 (OMIM: 606099) galectin-8 isoform b [Hom ( 317) 303 81.9 1e-15 NP_963838 (OMIM: 606099) galectin-8 isoform b [Hom ( 317) 303 81.9 1e-15 XP_011525275 (OMIM: 602518) PREDICTED: galectin-4 ( 310) 301 81.4 1.4e-15 XP_006721955 (OMIM: 601879) PREDICTED: galectin-9 ( 311) 301 81.4 1.4e-15 NP_002299 (OMIM: 601879) galectin-9 isoform short ( 323) 301 81.4 1.5e-15 XP_016880112 (OMIM: 601879) PREDICTED: galectin-9 ( 343) 301 81.4 1.5e-15 NP_033665 (OMIM: 601879) galectin-9 isoform long [ ( 355) 301 81.5 1.6e-15 NP_001136008 (OMIM: 606096) galectin-12 isoform 3 ( 327) 229 63.8 2.9e-10 NP_149092 (OMIM: 606096) galectin-12 isoform 2 [Ho ( 336) 229 63.8 3e-10 XP_016873947 (OMIM: 606096) PREDICTED: galectin-12 ( 252) 223 62.3 6.5e-10 NP_001035972 (OMIM: 617139) galectin-7 [Homo sapie ( 136) 216 60.4 1.3e-09 NP_002298 (OMIM: 600615) galectin-7 [Homo sapiens] ( 136) 216 60.4 1.3e-09 NP_002297 (OMIM: 153619) galectin-3 isoform 1 [Hom ( 250) 216 60.6 2.1e-09 XP_011535061 (OMIM: 153619) PREDICTED: galectin-3 ( 264) 216 60.6 2.2e-09 XP_016856764 (OMIM: 606099) PREDICTED: galectin-8 ( 226) 215 60.3 2.3e-09 XP_016856763 (OMIM: 606099) PREDICTED: galectin-8 ( 287) 215 60.4 2.8e-09 XP_011542490 (OMIM: 606099) PREDICTED: galectin-8 ( 329) 215 60.4 3.2e-09 XP_011523098 (OMIM: 601879) PREDICTED: galectin-9 ( 221) 213 59.8 3.2e-09 XP_006721958 (OMIM: 601879) PREDICTED: galectin-9 ( 234) 213 59.8 3.3e-09 NP_001317092 (OMIM: 601879) galectin-9 isoform 3 [ ( 246) 213 59.8 3.5e-09 XP_006721956 (OMIM: 601879) PREDICTED: galectin-9 ( 278) 213 59.9 3.9e-09 NP_982297 (OMIM: 607260) placental protein 13-like ( 168) 172 49.7 2.7e-06 NP_064514 (OMIM: 607260) placental protein 13-like ( 139) 168 48.7 4.5e-06 NP_001136009 (OMIM: 606096) galectin-12 isoform 4 ( 275) 138 41.5 0.0013 NP_001136007 (OMIM: 606096) galectin-12 isoform 1 ( 337) 138 41.6 0.0015 NP_002296 (OMIM: 150570) galectin-1 [Homo sapiens] ( 135) 124 37.9 0.0076 >>XP_011525276 (OMIM: 602518) PREDICTED: galectin-4 isof (192 aa) initn: 295 init1: 209 opt: 305 Z-score: 409.0 bits: 82.3 E(85289): 4.8e-16 Smith-Waterman score: 305; 31.8% identity (66.9% similar) in 154 aa overlap (17-169:39-188) 10 20 30 40 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSS-PVQADVYFPRLIVPFCGHIK :: ...:.: :.. ::. :... XP_011 GDLQLQSINFIGGQPLRPQGPPMMPPYPGPGHCHQQLNSLPTMEGPPTFNPPVPYFGRLQ 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 GGMRPGKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGE ::. . ... : : . .::::.. :.: .:.:.... . . ..::: ..: XP_011 GGLTARRTIIIKGYVPPTGKSFAINFKVGSS----GDIALHINPRMGNGTVVRNSLLNGS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 RGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGD : :.. : . :: : : : . : : ::.:...:..:::: ::..... .::..:.:: XP_011 WGSEEKKITHNPFGPGQFFDLSIRCGLDRFKVYANGQHLFDFAHRLSAFQRVDTLEIQGD 130 140 150 160 170 180 170 pF1KE0 LQITKLG . .. XP_011 VTLSYVQI 190 >>NP_006140 (OMIM: 602518) galectin-4 [Homo sapiens] (323 aa) initn: 317 init1: 209 opt: 305 Z-score: 405.7 bits: 82.4 E(85289): 7.4e-16 Smith-Waterman score: 305; 31.8% identity (66.9% similar) in 154 aa overlap (17-169:170-319) 10 20 30 40 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSS-PVQADVYFPRLIVPFCGHIK :: ...:.: :.. ::. :... NP_006 GDLQLQSINFIGGQPLRPQGPPMMPPYPGPGHCHQQLNSLPTMEGPPTFNPPVPYFGRLQ 140 150 160 170 180 190 50 60 70 80 90 100 pF1KE0 GGMRPGKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGE ::. . ... : : . .::::.. :.: .:.:.... . . ..::: ..: NP_006 GGLTARRTIIIKGYVPPTGKSFAINFKVGSS----GDIALHINPRMGNGTVVRNSLLNGS 200 210 220 230 240 250 110 120 130 140 150 160 pF1KE0 RGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGD : :.. : . :: : : : . : : ::.:...:..:::: ::..... .::..:.:: NP_006 WGSEEKKITHNPFGPGQFFDLSIRCGLDRFKVYANGQHLFDFAHRLSAFQRVDTLEIQGD 260 270 280 290 300 310 170 pF1KE0 LQITKLG . .. NP_006 VTLSYVQI 320 >-- initn: 134 init1: 85 opt: 191 Z-score: 255.0 bits: 54.5 E(85289): 1.8e-07 Smith-Waterman score: 191; 26.0% identity (60.0% similar) in 150 aa overlap (25-171:6-147) 10 20 30 40 50 60 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIV .: .: : : :. : ::. : .: ..:.. NP_006 MAYVPAPGYQPTYNPTL--PYYQPIPGGLNVGMSVYIQGVA 10 20 30 70 80 90 100 110 pF1KE0 DLNPESFAISLTCGDSEDPPADVAIELKAVFTD-RQLLRNSCISGERGEEQSAIPYFPFI . . . : .... : .:: .:::.... : ... :. .:. : :. . :: NP_006 SEHMKRFFVNFVVG--QDPGSDVAFHFNPRFDGWDKVVFNTLQGGKWGSEERKRSM-PFK 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 PDQPFRVE--ILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG :.. .: :: ..: :.:. .... ::. :. . ....::::. .. NP_006 KGAAFELVFIVLAEH--YKVVVNGNPFYEYGHRLP-LQMVTHLQVDGDLQLQSINFIGGQ 100 110 120 130 140 150 NP_006 PLRPQGPPMMPPYPGPGHCHQQLNSLPTMEGPPTFNPPVPYFGRLQGGLTARRTIIIKGY 160 170 180 190 200 210 >>NP_963839 (OMIM: 606099) galectin-8 isoform a [Homo sa (359 aa) initn: 353 init1: 191 opt: 304 Z-score: 403.7 bits: 82.2 E(85289): 9.5e-16 Smith-Waterman score: 304; 31.1% identity (64.1% similar) in 167 aa overlap (5-171:194-356) 10 20 30 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFP .: . .: :. .:..:. . . NP_963 SLELTEISRENVPKSGTPQLPSNRGGDISKIAPRTVYTKSKDSTVNHTLTCTKIPPMNYV 170 180 190 200 210 220 40 50 60 70 80 90 pF1KE0 RLIVPFCGHIKGGMRPGKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDR .:: .... : ::. :.: : :. : .:: ..: : :. :.:..:. .. . NP_963 SKRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSK----DIALHLNPRLNIK 230 240 250 260 270 100 110 120 130 140 150 pF1KE0 QLLRNSCISGERGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTL ..::: .. :::. : ::: : . :.. : :. .:.: :.: . ... ::.. : NP_963 AFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKEL 280 290 300 310 320 330 160 170 pF1KE0 SAIDTIKINGDLQITKLG :.:::..::::... .. NP_963 SSIDTLEINGDIHLLEVRSW 340 350 >-- initn: 191 init1: 176 opt: 215 Z-score: 286.1 bits: 60.4 E(85289): 3.4e-09 Smith-Waterman score: 215; 30.4% identity (58.8% similar) in 148 aa overlap (27-172:8-150) 10 20 30 40 50 60 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIV .: .: : ..:: : : . :: ... : : NP_963 MMLSLNNLQNIIYNP--VIPFVGTIPDQLDPGTLIVIRGHV 10 20 30 70 80 90 100 110 pF1KE0 DLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQ-LLRNSCISGERGEEQSAIPY-FPF . . : ..: :.: : ::::.... : .. :. :. . :.:. : : :: NP_963 PSDADRFQVDLQNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREE--ITYDTPF 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 IPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG .. :.. :. . .:.: :.:.. . . ::: :::. : : ..: ..: NP_963 KREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGP-EKIDTLGIYGKVNIHSIGFSFSSD 100 110 120 130 140 150 NP_963 LQSTQASSLELTEISRENVPKSGTPQLPSNRGGDISKIAPRTVYTKSKDSTVNHTLTCTK 160 170 180 190 200 210 >>NP_006490 (OMIM: 606099) galectin-8 isoform a [Homo sa (359 aa) initn: 353 init1: 191 opt: 304 Z-score: 403.7 bits: 82.2 E(85289): 9.5e-16 Smith-Waterman score: 304; 31.1% identity (64.1% similar) in 167 aa overlap (5-171:194-356) 10 20 30 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFP .: . .: :. .:..:. . . NP_006 SLELTEISRENVPKSGTPQLPSNRGGDISKIAPRTVYTKSKDSTVNHTLTCTKIPPMNYV 170 180 190 200 210 220 40 50 60 70 80 90 pF1KE0 RLIVPFCGHIKGGMRPGKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDR .:: .... : ::. :.: : :. : .:: ..: : :. :.:..:. .. . NP_006 SKRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSK----DIALHLNPRLNIK 230 240 250 260 270 100 110 120 130 140 150 pF1KE0 QLLRNSCISGERGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTL ..::: .. :::. : ::: : . :.. : :. .:.: :.: . ... ::.. : NP_006 AFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKEL 280 290 300 310 320 330 160 170 pF1KE0 SAIDTIKINGDLQITKLG :.:::..::::... .. NP_006 SSIDTLEINGDIHLLEVRSW 340 350 >-- initn: 191 init1: 176 opt: 215 Z-score: 286.1 bits: 60.4 E(85289): 3.4e-09 Smith-Waterman score: 215; 30.4% identity (58.8% similar) in 148 aa overlap (27-172:8-150) 10 20 30 40 50 60 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIV .: .: : ..:: : : . :: ... : : NP_006 MMLSLNNLQNIIYNP--VIPFVGTIPDQLDPGTLIVIRGHV 10 20 30 70 80 90 100 110 pF1KE0 DLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQ-LLRNSCISGERGEEQSAIPY-FPF . . : ..: :.: : ::::.... : .. :. :. . :.:. : : :: NP_006 PSDADRFQVDLQNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREE--ITYDTPF 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 IPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG .. :.. :. . .:.: :.:.. . . ::: :::. : : ..: ..: NP_006 KREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGP-EKIDTLGIYGKVNIHSIGFSFSSD 100 110 120 130 140 150 NP_006 LQSTQASSLELTEISRENVPKSGTPQLPSNRGGDISKIAPRTVYTKSKDSTVNHTLTCTK 160 170 180 190 200 210 >>NP_963837 (OMIM: 606099) galectin-8 isoform b [Homo sa (317 aa) initn: 353 init1: 191 opt: 303 Z-score: 403.2 bits: 81.9 E(85289): 1e-15 Smith-Waterman score: 303; 35.5% identity (68.8% similar) in 138 aa overlap (34-171:181-314) 10 20 30 40 50 60 pF1KE0 SVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIVDLN :.: .:: .... : ::. :.: : :. : NP_963 FSFSSDLQSTQASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNAN 160 170 180 190 200 210 70 80 90 100 110 120 pF1KE0 PESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQSAIPYFPFIPDQP .:: ..: : :.: .:..:. .. . ..::: .. :::. : ::: : . NP_963 AKSFNVDLLAGKSKD----IALHLNPRLNIKAFVRNSFLQESWGEEERNITSFPFSPGMY 220 230 240 250 260 130 140 150 160 170 pF1KE0 FRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG :.. : :. .:.: :.: . ... ::.. ::.:::..::::... .. NP_963 FEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW 270 280 290 300 310 >-- initn: 191 init1: 176 opt: 215 Z-score: 286.9 bits: 60.4 E(85289): 3.1e-09 Smith-Waterman score: 215; 30.4% identity (58.8% similar) in 148 aa overlap (27-172:8-150) 10 20 30 40 50 60 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIV .: .: : ..:: : : . :: ... : : NP_963 MMLSLNNLQNIIYNP--VIPFVGTIPDQLDPGTLIVIRGHV 10 20 30 70 80 90 100 110 pF1KE0 DLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQ-LLRNSCISGERGEEQSAIPY-FPF . . : ..: :.: : ::::.... : .. :. :. . :.:. : : :: NP_963 PSDADRFQVDLQNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREE--ITYDTPF 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 IPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG .. :.. :. . .:.: :.:.. . . ::: :::. : : ..: ..: NP_963 KREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGP-EKIDTLGIYGKVNIHSIGFSFSSD 100 110 120 130 140 150 NP_963 LQSTQASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNV 160 170 180 190 200 210 >>NP_963838 (OMIM: 606099) galectin-8 isoform b [Homo sa (317 aa) initn: 353 init1: 191 opt: 303 Z-score: 403.2 bits: 81.9 E(85289): 1e-15 Smith-Waterman score: 303; 35.5% identity (68.8% similar) in 138 aa overlap (34-171:181-314) 10 20 30 40 50 60 pF1KE0 SVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIVDLN :.: .:: .... : ::. :.: : :. : NP_963 FSFSSDLQSTQASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNAN 160 170 180 190 200 210 70 80 90 100 110 120 pF1KE0 PESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQSAIPYFPFIPDQP .:: ..: : :.: .:..:. .. . ..::: .. :::. : ::: : . NP_963 AKSFNVDLLAGKSKD----IALHLNPRLNIKAFVRNSFLQESWGEEERNITSFPFSPGMY 220 230 240 250 260 130 140 150 160 170 pF1KE0 FRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG :.. : :. .:.: :.: . ... ::.. ::.:::..::::... .. NP_963 FEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW 270 280 290 300 310 >-- initn: 191 init1: 176 opt: 215 Z-score: 286.9 bits: 60.4 E(85289): 3.1e-09 Smith-Waterman score: 215; 30.4% identity (58.8% similar) in 148 aa overlap (27-172:8-150) 10 20 30 40 50 60 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIV .: .: : ..:: : : . :: ... : : NP_963 MMLSLNNLQNIIYNP--VIPFVGTIPDQLDPGTLIVIRGHV 10 20 30 70 80 90 100 110 pF1KE0 DLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQ-LLRNSCISGERGEEQSAIPY-FPF . . : ..: :.: : ::::.... : .. :. :. . :.:. : : :: NP_963 PSDADRFQVDLQNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREE--ITYDTPF 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 IPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG .. :.. :. . .:.: :.:.. . . ::: :::. : : ..: ..: NP_963 KREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGP-EKIDTLGIYGKVNIHSIGFSFSSD 100 110 120 130 140 150 NP_963 LQSTQASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNV 160 170 180 190 200 210 >>XP_011525275 (OMIM: 602518) PREDICTED: galectin-4 isof (310 aa) initn: 317 init1: 209 opt: 301 Z-score: 400.7 bits: 81.4 E(85289): 1.4e-15 Smith-Waterman score: 301; 33.3% identity (69.7% similar) in 132 aa overlap (38-169:179-306) 10 20 30 40 50 60 pF1KE0 SDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIVDLNPESF ::. :...::. . ... : : . .:: XP_011 FIGGQPLRPQGPPMMPPYPTMEGPPTFNPPVPYFGRLQGGLTARRTIIIKGYVPPTGKSF 150 160 170 180 190 200 70 80 90 100 110 120 pF1KE0 AISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQSAIPYFPFIPDQPFRVE ::.. :.: .:.:.... . . ..::: ..: : :.. : . :: : : : . XP_011 AINFKVGSS----GDIALHINPRMGNGTVVRNSLLNGSWGSEEKKITHNPFGPGQFFDLS 210 220 230 240 250 260 130 140 150 160 170 pF1KE0 ILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG : : ::.:...:..:::: ::..... .::..:.::. .. XP_011 IRCGLDRFKVYANGQHLFDFAHRLSAFQRVDTLEIQGDVTLSYVQI 270 280 290 300 310 >-- initn: 134 init1: 85 opt: 191 Z-score: 255.3 bits: 54.5 E(85289): 1.8e-07 Smith-Waterman score: 191; 26.0% identity (60.0% similar) in 150 aa overlap (25-171:6-147) 10 20 30 40 50 60 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIV .: .: : : :. : ::. : .: ..:.. XP_011 MAYVPAPGYQPTYNPTL--PYYQPIPGGLNVGMSVYIQGVA 10 20 30 70 80 90 100 110 pF1KE0 DLNPESFAISLTCGDSEDPPADVAIELKAVFTD-RQLLRNSCISGERGEEQSAIPYFPFI . . . : .... : .:: .:::.... : ... :. .:. : :. . :: XP_011 SEHMKRFFVNFVVG--QDPGSDVAFHFNPRFDGWDKVVFNTLQGGKWGSEERKRSM-PFK 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 PDQPFRVE--ILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG :.. .: :: ..: :.:. .... ::. :. . ....::::. .. XP_011 KGAAFELVFIVLAEH--YKVVVNGNPFYEYGHRLP-LQMVTHLQVDGDLQLQSINFIGGQ 100 110 120 130 140 150 XP_011 PLRPQGPPMMPPYPTMEGPPTFNPPVPYFGRLQGGLTARRTIIIKGYVPPTGKSFAINFK 160 170 180 190 200 210 >>XP_006721955 (OMIM: 601879) PREDICTED: galectin-9 isof (311 aa) initn: 363 init1: 188 opt: 301 Z-score: 400.7 bits: 81.4 E(85289): 1.4e-15 Smith-Waterman score: 301; 32.9% identity (66.4% similar) in 152 aa overlap (23-171:164-309) 10 20 30 40 50 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPR--LIVPFCGHIKGGMRP .:.:. ...:. .:: : ::. : XP_006 ISVNGSVQLSYISFQTQTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYP 140 150 160 170 180 190 60 70 80 90 100 110 pF1KE0 GKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQ .:..:. : : . . : :.: :. .:..:. : . ..::. :.. : :. XP_006 SKSILLSGTVLPSAQRFHINLCSGNH------IAFHLNPRFDENAVVRNTQIDNSWGSEE 200 210 220 230 240 120 130 140 150 160 pF1KE0 SAIPY-FPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQIT ..: .::. : : : :::: ..: :::..::..:::...: .:. ....::.:.: XP_006 RSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINRLEVGGDIQLT 250 260 270 280 290 300 170 pF1KE0 KLG .. XP_006 HVQT 310 >-- initn: 201 init1: 83 opt: 213 Z-score: 284.4 bits: 59.9 E(85289): 4.2e-09 Smith-Waterman score: 213; 29.3% identity (59.9% similar) in 147 aa overlap (25-169:4-143) 10 20 30 40 50 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMG-I : :: : ::: : :.::.. : .. : : . XP_006 MAFSGSQAPYLSP--AVPFSGTIQGGLQDGLQITVNGTV 10 20 30 60 70 80 90 100 110 pF1KE0 VDLNPESFAISLTCGDSEDPPADVAIELKAVFTDR-QLLRNSCISGERGEEQSAIPYFPF .. . ::... : : . :.:.... : : .. :. .: : :. ..:: XP_006 LSSSGTRFAVNFQTGFSGN---DIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKT-HMPF 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 IPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG .:: . .: . :.:.:.: . ...::. . .:::..::..:.. XP_006 QKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVP-FHRVDTISVNGSVQLSYISFQTQTV 100 110 120 130 140 150 XP_006 IHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSAQRFHI 160 170 180 190 200 210 >>NP_002299 (OMIM: 601879) galectin-9 isoform short [Hom (323 aa) initn: 363 init1: 188 opt: 301 Z-score: 400.4 bits: 81.4 E(85289): 1.5e-15 Smith-Waterman score: 301; 32.9% identity (66.4% similar) in 152 aa overlap (23-171:176-321) 10 20 30 40 50 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPR--LIVPFCGHIKGGMRP .:.:. ...:. .:: : ::. : NP_002 SFQPPGVWPANPAPITQTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYP 150 160 170 180 190 200 60 70 80 90 100 110 pF1KE0 GKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQ .:..:. : : . . : :.: :. .:..:. : . ..::. :.. : :. NP_002 SKSILLSGTVLPSAQRFHINLCSGNH------IAFHLNPRFDENAVVRNTQIDNSWGSEE 210 220 230 240 250 120 130 140 150 160 pF1KE0 SAIPY-FPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQIT ..: .::. : : : :::: ..: :::..::..:::...: .:. ....::.:.: NP_002 RSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINRLEVGGDIQLT 260 270 280 290 300 310 170 pF1KE0 KLG .. NP_002 HVQT 320 >-- initn: 201 init1: 83 opt: 213 Z-score: 284.1 bits: 59.9 E(85289): 4.4e-09 Smith-Waterman score: 213; 29.3% identity (59.9% similar) in 147 aa overlap (25-169:4-143) 10 20 30 40 50 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMG-I : :: : ::: : :.::.. : .. : : . NP_002 MAFSGSQAPYLSP--AVPFSGTIQGGLQDGLQITVNGTV 10 20 30 60 70 80 90 100 110 pF1KE0 VDLNPESFAISLTCGDSEDPPADVAIELKAVFTDR-QLLRNSCISGERGEEQSAIPYFPF .. . ::... : : . :.:.... : : .. :. .: : :. ..:: NP_002 LSSSGTRFAVNFQTGFSGN---DIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKT-HMPF 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 IPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG .:: . .: . :.:.:.: . ...::. . .:::..::..:.. NP_002 QKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVP-FHRVDTISVNGSVQLSYISFQPPGV 100 110 120 130 140 150 NP_002 WPANPAPITQTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYPSKSILLS 160 170 180 190 200 210 >>XP_016880112 (OMIM: 601879) PREDICTED: galectin-9 isof (343 aa) initn: 363 init1: 188 opt: 301 Z-score: 400.0 bits: 81.4 E(85289): 1.5e-15 Smith-Waterman score: 301; 32.9% identity (66.4% similar) in 152 aa overlap (23-171:196-341) 10 20 30 40 50 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPR--LIVPFCGHIKGGMRP .:.:. ...:. .:: : ::. : XP_016 QPVCFPPRPRGRRQKTQTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYP 170 180 190 200 210 220 60 70 80 90 100 110 pF1KE0 GKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQ .:..:. : : . . : :.: :. .:..:. : . ..::. :.. : :. XP_016 SKSILLSGTVLPSAQRFHINLCSGNH------IAFHLNPRFDENAVVRNTQIDNSWGSEE 230 240 250 260 270 120 130 140 150 160 pF1KE0 SAIPY-FPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQIT ..: .::. : : : :::: ..: :::..::..:::...: .:. ....::.:.: XP_016 RSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINRLEVGGDIQLT 280 290 300 310 320 330 170 pF1KE0 KLG .. XP_016 HVQT 340 >-- initn: 201 init1: 83 opt: 213 Z-score: 283.7 bits: 59.9 E(85289): 4.6e-09 Smith-Waterman score: 213; 29.3% identity (59.9% similar) in 147 aa overlap (25-169:4-143) 10 20 30 40 50 pF1KE0 MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMG-I : :: : ::: : :.::.. : .. : : . XP_016 MAFSGSQAPYLSP--AVPFSGTIQGGLQDGLQITVNGTV 10 20 30 60 70 80 90 100 110 pF1KE0 VDLNPESFAISLTCGDSEDPPADVAIELKAVFTDR-QLLRNSCISGERGEEQSAIPYFPF .. . ::... : : . :.:.... : : .. :. .: : :. ..:: XP_016 LSSSGTRFAVNFQTGFSGN---DIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKT-HMPF 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 IPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG .:: . .: . :.:.:.: . ...::. . .:::..::..:.. XP_016 QKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVP-FHRVDTISVNGSVQLSYISFQNPRT 100 110 120 130 140 150 XP_016 VPVQPAFSTVPFSQPVCFPPRPRGRRQKTQTVIHTVQSAPGQMFSTPAIPPMMYPHPAYP 160 170 180 190 200 210 172 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:53:21 2016 done: Thu Nov 3 20:53:22 2016 Total Scan time: 5.500 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]