FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0218, 178 aa 1>>>pF1KE0218 178 - 178 aa - 178 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0478+/-0.00099; mu= 14.0338+/- 0.059 mean_var=63.1123+/-12.899, 0's: 0 Z-trim(103.4): 15 B-trim: 0 in 0/52 Lambda= 0.161442 statistics sampled from 7391 (7395) to 7391 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.611), E-opt: 0.2 (0.227), width: 16 Scan time: 1.590 The best scores are: opt bits E(32554) CCDS5767.1 CAV1 gene_id:857|Hs108|chr7 ( 178) 1200 288.1 2e-78 CCDS55156.1 CAV1 gene_id:857|Hs108|chr7 ( 147) 989 238.9 1.1e-63 CCDS2569.1 CAV3 gene_id:859|Hs108|chr3 ( 151) 703 172.3 1.2e-43 CCDS5766.1 CAV2 gene_id:858|Hs108|chr7 ( 162) 355 91.2 3.3e-19 >>CCDS5767.1 CAV1 gene_id:857|Hs108|chr7 (178 aa) initn: 1200 init1: 1200 opt: 1200 Z-score: 1521.5 bits: 288.1 E(32554): 2e-78 Smith-Waterman score: 1200; 100.0% identity (100.0% similar) in 178 aa overlap (1-178:1-178) 10 20 30 40 50 60 pF1KE0 MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 DDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFA 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 ILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 ILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI 130 140 150 160 170 >>CCDS55156.1 CAV1 gene_id:857|Hs108|chr7 (147 aa) initn: 989 init1: 989 opt: 989 Z-score: 1257.1 bits: 238.9 E(32554): 1.1e-63 Smith-Waterman score: 989; 100.0% identity (100.0% similar) in 147 aa overlap (32-178:1-147) 10 20 30 40 50 60 pF1KE0 SGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLND :::::::::::::::::::::::::::::: CCDS55 MADELSEKQVYDAHTKEIDLVNRDPKHLND 10 20 30 70 80 90 100 110 120 pF1KE0 DVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAI 40 50 60 70 80 90 130 140 150 160 170 pF1KE0 LSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI 100 110 120 130 140 >>CCDS2569.1 CAV3 gene_id:859|Hs108|chr3 (151 aa) initn: 691 init1: 678 opt: 703 Z-score: 896.9 bits: 172.3 E(32554): 1.2e-43 Smith-Waterman score: 703; 64.0% identity (87.3% similar) in 150 aa overlap (32-178:2-151) 10 20 30 40 50 pF1KE0 SGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADE---LSEKQVYDAHTKEIDLVNRDPKH ::.: : . : : : :::::::::::. CCDS25 MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKN 10 20 30 60 70 80 90 100 110 pF1KE0 LNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIY .:.:.::.::::::::: ::.::::.::.:.:::::.::: :::::.:.:.:.::.::. CCDS25 INEDIVKVDFEDVIAEPVGTYSFDGVWKVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFL 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 FAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI :: .:: :::::::::::.::::::::..::. ..: :.::: :.:.. :.... :.::. CCDS25 FACISFCHIWAVVPCIKSYLIEIQCISHIYSLCIRTFCNPLFAALGQVCSSIKVVLRKEV 100 110 120 130 140 150 >>CCDS5766.1 CAV2 gene_id:858|Hs108|chr7 (162 aa) initn: 359 init1: 321 opt: 355 Z-score: 458.4 bits: 91.2 E(32554): 3.3e-19 Smith-Waterman score: 355; 40.8% identity (74.4% similar) in 125 aa overlap (53-177:39-162) 30 40 50 60 70 80 pF1KE0 NIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFD .:::..::. . :. :::::::: ::::: CCDS57 DVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD 10 20 30 40 50 60 90 100 110 120 130 140 pF1KE0 GIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQ .: : . : ..:: .:..:.....::.:.: :: :: :: :::: ..: .:. :. . CCDS57 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP 70 80 90 100 110 120 150 160 170 pF1KE0 CISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI .. ... . .. :: .::. ::.: ..:... CCDS57 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD 130 140 150 160 178 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:49:10 2016 done: Sat Nov 5 01:49:10 2016 Total Scan time: 1.590 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]