FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0221, 96 aa 1>>>pF1KE0221 96 - 96 aa - 96 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.4600+/-0.000275; mu= 12.9359+/- 0.017 mean_var=50.2763+/- 9.905, 0's: 0 Z-trim(118.7): 53 B-trim: 0 in 0/54 Lambda= 0.180881 statistics sampled from 31784 (31837) to 31784 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.373), width: 16 Scan time: 3.600 The best scores are: opt bits E(85289) NP_002972 (OMIM: 182281) C-C motif chemokine 1 pre ( 96) 670 181.6 1.7e-46 NP_005399 (OMIM: 601391) C-C motif chemokine 13 pr ( 98) 193 57.1 5.2e-09 NP_005614 (OMIM: 602283) C-C motif chemokine 8 pre ( 99) 190 56.3 9e-09 NP_996890 (OMIM: 603782) C-C motif chemokine 4-lik ( 92) 188 55.8 1.2e-08 NP_002975 (OMIM: 182284) C-C motif chemokine 4 pre ( 92) 185 55.0 2.1e-08 NP_066286 (OMIM: 601395,609423) C-C motif chemokin ( 93) 182 54.2 3.6e-08 NP_001001437 (OMIM: 609468) C-C motif chemokine 3- ( 93) 182 54.2 3.6e-08 NP_006264 (OMIM: 158106) C-C motif chemokine 7 pre ( 99) 179 53.5 6.6e-08 NP_002974 (OMIM: 182283,609423) C-C motif chemokin ( 92) 178 53.2 7.4e-08 NP_116739 (OMIM: 601392) C-C motif chemokine 14 is ( 93) 171 51.4 2.7e-07 NP_002977 (OMIM: 600807,601156,609423) eotaxin pre ( 97) 169 50.8 3.9e-07 NP_002973 (OMIM: 158105,182940,607948,609423) C-C ( 99) 165 49.8 8.3e-07 NP_116738 (OMIM: 601392) C-C motif chemokine 14 is ( 109) 164 49.6 1.1e-06 NP_006063 (OMIM: 604697) C-C motif chemokine 26 pr ( 94) 162 49.0 1.4e-06 XP_016867161 (OMIM: 604697) PREDICTED: C-C motif c ( 94) 162 49.0 1.4e-06 XP_016867160 (OMIM: 604697) PREDICTED: C-C motif c ( 148) 162 49.1 2e-06 XP_011514762 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 156 47.5 4.9e-06 XP_011514761 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 156 47.5 4.9e-06 NP_002982 (OMIM: 602495) C-C motif chemokine 24 pr ( 119) 156 47.5 4.9e-06 NP_001278397 (OMIM: 610757) C-C motif chemokine 4- ( 87) 146 44.8 2.3e-05 NP_002979 (OMIM: 603757) C-C motif chemokine 18 pr ( 89) 144 44.3 3.4e-05 NP_116741 (OMIM: 601393) C-C motif chemokine 15 pr ( 113) 142 43.8 5.9e-05 NP_002976 (OMIM: 187011) C-C motif chemokine 5 iso ( 91) 141 43.5 5.9e-05 NP_665905 (OMIM: 602494) C-C motif chemokine 23 is ( 120) 136 42.3 0.00018 NP_005055 (OMIM: 602494) C-C motif chemokine 23 is ( 137) 136 42.3 0.0002 XP_016879020 (OMIM: 602957) PREDICTED: C-C motif c ( 93) 133 41.4 0.00026 NP_002981 (OMIM: 602957) C-C motif chemokine 22 pr ( 93) 133 41.4 0.00026 NP_004581 (OMIM: 601394) C-C motif chemokine 16 pr ( 120) 129 40.5 0.00065 XP_005258077 (OMIM: 601394) PREDICTED: C-C motif c ( 120) 129 40.5 0.00065 NP_002980 (OMIM: 602737) C-C motif chemokine 21 pr ( 134) 122 38.7 0.0025 XP_011516306 (OMIM: 602737) PREDICTED: C-C motif c ( 145) 122 38.7 0.0027 NP_001278400 (OMIM: 610757) C-C motif chemokine 4- ( 103) 116 37.0 0.006 NP_006265 (OMIM: 602227) C-C motif chemokine 19 pr ( 98) 114 36.5 0.0083 NP_001278401 (OMIM: 610757) C-C motif chemokine 4- ( 96) 113 36.2 0.0098 >>NP_002972 (OMIM: 182281) C-C motif chemokine 1 precurs (96 aa) initn: 670 init1: 670 opt: 670 Z-score: 955.6 bits: 181.6 E(85289): 1.7e-46 Smith-Waterman score: 670; 100.0% identity (100.0% similar) in 96 aa overlap (1-96:1-96) 10 20 30 40 50 60 pF1KE0 MQIITTALVCLLLAGMWPEDVDSKSMQVPFSRCCFSFAEQEIPLRAILCYRNTSSICSNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MQIITTALVCLLLAGMWPEDVDSKSMQVPFSRCCFSFAEQEIPLRAILCYRNTSSICSNE 10 20 30 40 50 60 70 80 90 pF1KE0 GLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK :::::::::::::::::::::::::::::::::::: NP_002 GLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK 70 80 90 >>NP_005399 (OMIM: 601391) C-C motif chemokine 13 precur (98 aa) initn: 203 init1: 157 opt: 193 Z-score: 282.8 bits: 57.1 E(85289): 5.2e-09 Smith-Waterman score: 193; 37.5% identity (67.0% similar) in 88 aa overlap (4-88:3-89) 10 20 30 40 50 pF1KE0 MQIITTALVCLLL--AGMWPEDV-DSKSMQVPFSRCCFSFAEQEIPLRAILCYRNTSSIC ....:.:::: :.. :. . . ...:: : :::.:. ..: :. . : :.: : NP_005 MKVSAVLLCLLLMTAAFNPQGLAQPDALNVP-STCCFTFSSKKISLQRLKSYVITTSRC 10 20 30 40 50 60 70 80 90 pF1KE0 SNEGLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK ....::. : ::: :: ::: . : : NP_005 PQKAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT 60 70 80 90 >>NP_005614 (OMIM: 602283) C-C motif chemokine 8 precurs (99 aa) initn: 157 init1: 78 opt: 190 Z-score: 278.5 bits: 56.3 E(85289): 9e-09 Smith-Waterman score: 190; 37.1% identity (67.4% similar) in 89 aa overlap (4-88:3-90) 10 20 30 40 50 pF1KE0 MQIITTALVCLLL--AGMWPEDV-DSKSMQVPFSRCCFSFAEQEIPLRAILCYRNTSSI- ...::.:::: : . :. . . :...:.. :::. ...::.. . : ..: NP_005 MKVSAALLCLLLMAATFSPQGLAQPDSVSIPIT-CCFNVINRKIPIQRLESYTRITNIQ 10 20 30 40 50 60 70 80 90 pF1KE0 CSNEGLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK : .:..::: :::::.:: ::. : : NP_005 CPKEAVIFKTKRGKEVCADPKERWVRDSMKHLDQIFQNLKP 60 70 80 90 >>NP_996890 (OMIM: 603782) C-C motif chemokine 4-like pr (92 aa) initn: 175 init1: 175 opt: 188 Z-score: 276.1 bits: 55.8 E(85289): 1.2e-08 Smith-Waterman score: 188; 34.1% identity (69.4% similar) in 85 aa overlap (1-84:1-85) 10 20 30 40 50 pF1KE0 MQIITTALVCLLLAGMWPEDVDSKSMQV-PFSRCCFSFAEQEIPLRAILCYRNTSSICSN :.. .:.: :.:.. . . : : : . ::::.. ...: .. : .:::.::. NP_996 MKLCVTVLSLLVLVAAFCSLALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQ 10 20 30 40 50 60 60 70 80 90 pF1KE0 EGLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK ...:. ::::..:: . .:::.. NP_996 PAVVFQTKRGKQVCADPSESWVQEYVYDLELN 70 80 90 >>NP_002975 (OMIM: 182284) C-C motif chemokine 4 precurs (92 aa) initn: 167 init1: 167 opt: 185 Z-score: 271.9 bits: 55.0 E(85289): 2.1e-08 Smith-Waterman score: 185; 32.9% identity (69.4% similar) in 85 aa overlap (1-84:1-85) 10 20 30 40 50 pF1KE0 MQIITTALVCLLLAGMWPEDVDSKSMQV-PFSRCCFSFAEQEIPLRAILCYRNTSSICSN :.. .:.: :.:.. . . : : : . ::::.. ...: .. : .:::.::. NP_002 MKLCVTVLSLLMLVAAFCSPALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQ 10 20 30 40 50 60 60 70 80 90 pF1KE0 EGLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK ...:. ::.:..:: . .:::.. NP_002 PAVVFQTKRSKQVCADPSESWVQEYVYDLELN 70 80 90 >>NP_066286 (OMIM: 601395,609423) C-C motif chemokine 3- (93 aa) initn: 198 init1: 164 opt: 182 Z-score: 267.6 bits: 54.2 E(85289): 3.6e-08 Smith-Waterman score: 182; 37.6% identity (64.7% similar) in 85 aa overlap (1-84:1-85) 10 20 30 40 50 pF1KE0 MQIITTALVCLLLAGMWPEDVDSKSMQVPF-SRCCFSFAEQEIPLRAILCYRNTSSICSN ::. :.::. :: . ..: : . . . ::::.. ..:: : : .::: ::. NP_066 MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSK 10 20 30 40 50 60 60 70 80 90 pF1KE0 EGLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK ..:: :::...:: . :::.. NP_066 PSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 70 80 90 >>NP_001001437 (OMIM: 609468) C-C motif chemokine 3-like (93 aa) initn: 198 init1: 164 opt: 182 Z-score: 267.6 bits: 54.2 E(85289): 3.6e-08 Smith-Waterman score: 182; 37.6% identity (64.7% similar) in 85 aa overlap (1-84:1-85) 10 20 30 40 50 pF1KE0 MQIITTALVCLLLAGMWPEDVDSKSMQVPF-SRCCFSFAEQEIPLRAILCYRNTSSICSN ::. :.::. :: . ..: : . . . ::::.. ..:: : : .::: ::. NP_001 MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSK 10 20 30 40 50 60 60 70 80 90 pF1KE0 EGLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK ..:: :::...:: . :::.. NP_001 PSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 70 80 90 >>NP_006264 (OMIM: 158106) C-C motif chemokine 7 precurs (99 aa) initn: 137 init1: 107 opt: 179 Z-score: 263.0 bits: 53.5 E(85289): 6.6e-08 Smith-Waterman score: 179; 39.1% identity (59.8% similar) in 87 aa overlap (5-88:4-90) 10 20 30 40 50 pF1KE0 MQIITTALVCLLL--AGMWPEDVDSKSMQVPFSRCCFSFAEQEIPLRAILCYR-NTSSIC ..::.:::: :.. :. . . . ::. : ...:: . . :: .::: : NP_006 MKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHC 10 20 30 40 50 60 70 80 90 pF1KE0 SNEGLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK :..::: : :: :: : ::: : : NP_006 PREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL 60 70 80 90 >>NP_002974 (OMIM: 182283,609423) C-C motif chemokine 3 (92 aa) initn: 186 init1: 177 opt: 178 Z-score: 262.0 bits: 53.2 E(85289): 7.4e-08 Smith-Waterman score: 178; 37.6% identity (67.1% similar) in 85 aa overlap (1-84:1-84) 10 20 30 40 50 pF1KE0 MQIITTALVCLLLAGMWPEDVD-SKSMQVPFSRCCFSFAEQEIPLRAILCYRNTSSICSN ::. :.::. :: . .. . : . ..: . ::::.. ..:: : : .::: ::. NP_002 MQVSTAALAVLLCTMALCNQFSASLAADTP-TACCFSYTSRQIPQNFIADYFETSSQCSK 10 20 30 40 50 60 70 80 90 pF1KE0 EGLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK :.:: ::....:: . :::.. NP_002 PGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA 60 70 80 90 >>NP_116739 (OMIM: 601392) C-C motif chemokine 14 isofor (93 aa) initn: 167 init1: 159 opt: 171 Z-score: 252.1 bits: 51.4 E(85289): 2.7e-07 Smith-Waterman score: 171; 31.9% identity (62.6% similar) in 91 aa overlap (1-89:1-91) 10 20 30 40 50 pF1KE0 MQIITTALVCLLLAGMWPEDVDSKSMQVPF--SRCCFSFAEQEIPLRAILCYRNTSSICS :.: ..:. .:: . .: . :. :.:::... .:: . :. : .:.: :: NP_116 MKISVAAIPFFLLITIALGTKTESSSRGPYHPSECCFTYTTYKIPRQRIMDYYETNSQCS 10 20 30 40 50 60 60 70 80 90 pF1KE0 NEGLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK . :..: :::. .:. . ::: . : .. NP_116 KPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN 70 80 90 96 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:48:19 2016 done: Thu Nov 3 20:48:19 2016 Total Scan time: 3.600 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]