FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0223, 79 aa 1>>>pF1KE0223 79 - 79 aa - 79 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7453+/-0.000276; mu= 11.8017+/- 0.017 mean_var=75.2647+/-15.235, 0's: 0 Z-trim(121.4): 106 B-trim: 2068 in 2/55 Lambda= 0.147835 statistics sampled from 37846 (37993) to 37846 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.823), E-opt: 0.2 (0.445), width: 16 Scan time: 4.020 The best scores are: opt bits E(85289) NP_004048 (OMIM: 302020) protein S100-G [Homo sapi ( 79) 505 115.4 9.9e-27 XP_016885330 (OMIM: 302020) PREDICTED: protein S10 ( 79) 505 115.4 9.9e-27 NP_006262 (OMIM: 176940) protein S100-A1 [Homo sap ( 94) 196 49.5 7.7e-07 NP_005971 (OMIM: 600614) protein S100-P [Homo sapi ( 95) 180 46.1 8.3e-06 XP_016864661 (OMIM: 610103) PREDICTED: protein S10 ( 99) 170 44.0 3.7e-05 XP_011541543 (OMIM: 610103) PREDICTED: protein S10 ( 99) 170 44.0 3.7e-05 XP_016864662 (OMIM: 610103) PREDICTED: protein S10 ( 99) 170 44.0 3.7e-05 XP_011541542 (OMIM: 610103) PREDICTED: protein S10 ( 99) 170 44.0 3.7e-05 XP_011541546 (OMIM: 610103) PREDICTED: protein S10 ( 99) 170 44.0 3.7e-05 XP_016864660 (OMIM: 610103) PREDICTED: protein S10 ( 99) 170 44.0 3.7e-05 NP_570128 (OMIM: 610103) protein S100-Z [Homo sapi ( 99) 170 44.0 3.7e-05 XP_011541547 (OMIM: 610103) PREDICTED: protein S10 ( 99) 170 44.0 3.7e-05 XP_011541541 (OMIM: 610103) PREDICTED: protein S10 ( 99) 170 44.0 3.7e-05 XP_016883913 (OMIM: 176990) PREDICTED: protein S10 ( 92) 167 43.4 5.5e-05 NP_006263 (OMIM: 176990) protein S100-B [Homo sapi ( 92) 167 43.4 5.5e-05 NP_002952 (OMIM: 114210) protein S100-A4 [Homo sap ( 101) 160 41.9 0.00017 NP_062427 (OMIM: 114210) protein S100-A4 [Homo sap ( 101) 160 41.9 0.00017 XP_016857523 (OMIM: 601989) PREDICTED: protein S10 ( 98) 159 41.7 0.00019 XP_011508165 (OMIM: 601989) PREDICTED: protein S10 ( 98) 159 41.7 0.00019 XP_011508164 (OMIM: 601989) PREDICTED: protein S10 ( 98) 159 41.7 0.00019 NP_001019382 (OMIM: 601989) protein S100-A13 [Homo ( 98) 159 41.7 0.00019 NP_001019384 (OMIM: 601989) protein S100-A13 [Homo ( 98) 159 41.7 0.00019 NP_001019383 (OMIM: 601989) protein S100-A13 [Homo ( 98) 159 41.7 0.00019 XP_011508166 (OMIM: 601989) PREDICTED: protein S10 ( 98) 159 41.7 0.00019 XP_016857525 (OMIM: 601989) PREDICTED: protein S10 ( 98) 159 41.7 0.00019 XP_016857524 (OMIM: 601989) PREDICTED: protein S10 ( 98) 159 41.7 0.00019 NP_001019381 (OMIM: 601989) protein S100-A13 [Homo ( 98) 159 41.7 0.00019 NP_005970 (OMIM: 601989) protein S100-A13 [Homo sa ( 98) 159 41.7 0.00019 XP_005245491 (OMIM: 601989) PREDICTED: protein S10 ( 98) 159 41.7 0.00019 NP_002956 (OMIM: 123886) protein S100-A9 [Homo sap ( 114) 157 41.3 0.00028 NP_001009931 (OMIM: 616293) hornerin [Homo sapiens (2850) 172 45.9 0.00029 NP_005611 (OMIM: 603114) protein S100-A11 [Homo sa ( 105) 156 41.1 0.00031 NP_001116437 (OMIM: 613259) repetin [Homo sapiens] ( 784) 165 43.8 0.00033 NP_002953 (OMIM: 176991) protein S100-A5 [Homo sap ( 92) 154 40.6 0.00038 NP_005612 (OMIM: 603112) protein S100-A12 [Homo sa ( 92) 154 40.6 0.00038 XP_016857521 (OMIM: 176991) PREDICTED: protein S10 ( 92) 154 40.6 0.00038 XP_016857520 (OMIM: 176991) PREDICTED: protein S10 ( 92) 154 40.6 0.00038 XP_011508162 (OMIM: 176991) PREDICTED: protein S10 ( 104) 154 40.6 0.00041 XP_016857519 (OMIM: 176991) PREDICTED: protein S10 ( 110) 154 40.7 0.00043 XP_016857518 (OMIM: 176991) PREDICTED: protein S10 ( 133) 154 40.7 0.00049 NP_057274 (OMIM: 611312) cornulin [Homo sapiens] ( 495) 160 42.6 0.00051 NP_001306130 (OMIM: 123885) protein S100-A8 isofor ( 93) 150 39.7 0.00069 NP_002955 (OMIM: 123885) protein S100-A8 isoform d ( 93) 150 39.7 0.00069 NP_001306127 (OMIM: 123885) protein S100-A8 isofor ( 101) 150 39.8 0.00073 NP_001306126 (OMIM: 123885) protein S100-A8 isofor ( 116) 150 39.8 0.0008 NP_001306125 (OMIM: 123885) protein S100-A8 isofor ( 117) 150 39.8 0.00081 NP_055439 (OMIM: 114110) protein S100-A6 [Homo sap ( 90) 148 39.3 0.0009 XP_016857522 (OMIM: 114110) PREDICTED: protein S10 ( 90) 148 39.3 0.0009 NP_002957 (OMIM: 114085) protein S100-A10 [Homo sa ( 97) 148 39.3 0.00095 NP_005969 (OMIM: 176993) protein S100-A2 [Homo sap ( 97) 146 38.9 0.0013 >>NP_004048 (OMIM: 302020) protein S100-G [Homo sapiens] (79 aa) initn: 505 init1: 505 opt: 505 Z-score: 600.9 bits: 115.4 E(85289): 9.9e-27 Smith-Waterman score: 505; 100.0% identity (100.0% similar) in 79 aa overlap (1-79:1-79) 10 20 30 40 50 60 pF1KE0 MSTKKSPEELKRIFEKYAAKEGDPDQLSKDELKLLIQAEFPSLLKGPNTLDDLFQELDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSTKKSPEELKRIFEKYAAKEGDPDQLSKDELKLLIQAEFPSLLKGPNTLDDLFQELDKN 10 20 30 40 50 60 70 pF1KE0 GDGEVSFEEFQVLVKKISQ ::::::::::::::::::: NP_004 GDGEVSFEEFQVLVKKISQ 70 >>XP_016885330 (OMIM: 302020) PREDICTED: protein S100-G (79 aa) initn: 505 init1: 505 opt: 505 Z-score: 600.9 bits: 115.4 E(85289): 9.9e-27 Smith-Waterman score: 505; 100.0% identity (100.0% similar) in 79 aa overlap (1-79:1-79) 10 20 30 40 50 60 pF1KE0 MSTKKSPEELKRIFEKYAAKEGDPDQLSKDELKLLIQAEFPSLLKGPNTLDDLFQELDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSTKKSPEELKRIFEKYAAKEGDPDQLSKDELKLLIQAEFPSLLKGPNTLDDLFQELDKN 10 20 30 40 50 60 70 pF1KE0 GDGEVSFEEFQVLVKKISQ ::::::::::::::::::: XP_016 GDGEVSFEEFQVLVKKISQ 70 >>NP_006262 (OMIM: 176940) protein S100-A1 [Homo sapiens (94 aa) initn: 196 init1: 107 opt: 196 Z-score: 243.8 bits: 49.5 E(85289): 7.7e-07 Smith-Waterman score: 196; 44.6% identity (75.7% similar) in 74 aa overlap (8-78:10-83) 10 20 30 40 50 pF1KE0 MSTKKSPEELKRIFEKYAAKEGDPDQLSKDELKLLIQAEFPSLL---KGPNTLDDLFQ : : .:. ...:::: .::: ::: :.:.:. ..: : ...: ... NP_006 MGSELETAMETLINVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQKDVDAVDKVMK 10 20 30 40 50 60 60 70 pF1KE0 ELDKNGDGEVSFEEFQVLVKKISQ :::.::::::.:.:. ::: .. NP_006 ELDENGDGEVDFQEYVVLVAALTVACNNFFWENS 70 80 90 >>NP_005971 (OMIM: 600614) protein S100-P [Homo sapiens] (95 aa) initn: 151 init1: 76 opt: 180 Z-score: 225.3 bits: 46.1 E(85289): 8.3e-06 Smith-Waterman score: 180; 40.6% identity (76.8% similar) in 69 aa overlap (13-78:14-82) 10 20 30 40 50 pF1KE0 MSTKKSPEELKRIFEKYAAKEGDPDQLSKDELKLLIQAEFPSLL---KGPNTLDDLFQE .: .:...::. . :.: :::.:.. :.:..: : ...: :... NP_005 MTELETAMGMIIDVFSRYSGSEGSTQTLTKGELKVLMEKELPGFLQSGKDKDAVDKLLKD 10 20 30 40 50 60 60 70 pF1KE0 LDKNGDGEVSFEEFQVLVKKISQ :: :::..:.: :: :.: :. NP_005 LDANGDAQVDFSEFIVFVAAITSACHKYFEKAGLK 70 80 90 >>XP_016864661 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 199 init1: 100 opt: 170 Z-score: 213.5 bits: 44.0 E(85289): 3.7e-05 Smith-Waterman score: 170; 43.2% identity (68.9% similar) in 74 aa overlap (8-78:10-83) 10 20 30 40 50 pF1KE0 MSTKKSPEELKRIFEKYAAKEGDPDQLSKDELKLLIQ---AEFPSLLKGPNTLDDLFQ . . :::..:..:: .::: :::::.: .:: : : . .: . : XP_016 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 10 20 30 40 50 60 60 70 pF1KE0 ELDKNGDGEVSFEEFQVLVKKISQ .:: : :.::.:.:: :.: .. XP_016 DLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 70 80 90 >>XP_011541543 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 199 init1: 100 opt: 170 Z-score: 213.5 bits: 44.0 E(85289): 3.7e-05 Smith-Waterman score: 170; 43.2% identity (68.9% similar) in 74 aa overlap (8-78:10-83) 10 20 30 40 50 pF1KE0 MSTKKSPEELKRIFEKYAAKEGDPDQLSKDELKLLIQ---AEFPSLLKGPNTLDDLFQ . . :::..:..:: .::: :::::.: .:: : : . .: . : XP_011 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 10 20 30 40 50 60 60 70 pF1KE0 ELDKNGDGEVSFEEFQVLVKKISQ .:: : :.::.:.:: :.: .. XP_011 DLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 70 80 90 >>XP_016864662 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 199 init1: 100 opt: 170 Z-score: 213.5 bits: 44.0 E(85289): 3.7e-05 Smith-Waterman score: 170; 43.2% identity (68.9% similar) in 74 aa overlap (8-78:10-83) 10 20 30 40 50 pF1KE0 MSTKKSPEELKRIFEKYAAKEGDPDQLSKDELKLLIQ---AEFPSLLKGPNTLDDLFQ . . :::..:..:: .::: :::::.: .:: : : . .: . : XP_016 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 10 20 30 40 50 60 60 70 pF1KE0 ELDKNGDGEVSFEEFQVLVKKISQ .:: : :.::.:.:: :.: .. XP_016 DLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 70 80 90 >>XP_011541542 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 199 init1: 100 opt: 170 Z-score: 213.5 bits: 44.0 E(85289): 3.7e-05 Smith-Waterman score: 170; 43.2% identity (68.9% similar) in 74 aa overlap (8-78:10-83) 10 20 30 40 50 pF1KE0 MSTKKSPEELKRIFEKYAAKEGDPDQLSKDELKLLIQ---AEFPSLLKGPNTLDDLFQ . . :::..:..:: .::: :::::.: .:: : : . .: . : XP_011 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 10 20 30 40 50 60 60 70 pF1KE0 ELDKNGDGEVSFEEFQVLVKKISQ .:: : :.::.:.:: :.: .. XP_011 DLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 70 80 90 >>XP_011541546 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 199 init1: 100 opt: 170 Z-score: 213.5 bits: 44.0 E(85289): 3.7e-05 Smith-Waterman score: 170; 43.2% identity (68.9% similar) in 74 aa overlap (8-78:10-83) 10 20 30 40 50 pF1KE0 MSTKKSPEELKRIFEKYAAKEGDPDQLSKDELKLLIQ---AEFPSLLKGPNTLDDLFQ . . :::..:..:: .::: :::::.: .:: : : . .: . : XP_011 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 10 20 30 40 50 60 60 70 pF1KE0 ELDKNGDGEVSFEEFQVLVKKISQ .:: : :.::.:.:: :.: .. XP_011 DLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 70 80 90 >>XP_016864660 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 199 init1: 100 opt: 170 Z-score: 213.5 bits: 44.0 E(85289): 3.7e-05 Smith-Waterman score: 170; 43.2% identity (68.9% similar) in 74 aa overlap (8-78:10-83) 10 20 30 40 50 pF1KE0 MSTKKSPEELKRIFEKYAAKEGDPDQLSKDELKLLIQ---AEFPSLLKGPNTLDDLFQ . . :::..:..:: .::: :::::.: .:: : : . .: . : XP_016 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 10 20 30 40 50 60 60 70 pF1KE0 ELDKNGDGEVSFEEFQVLVKKISQ .:: : :.::.:.:: :.: .. XP_016 DLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 70 80 90 79 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:47:01 2016 done: Thu Nov 3 20:47:02 2016 Total Scan time: 4.020 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]