FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0226, 128 aa 1>>>pF1KE0226 128 - 128 aa - 128 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8763+/-0.000327; mu= 12.9560+/- 0.020 mean_var=58.1607+/-11.539, 0's: 0 Z-trim(115.3): 46 B-trim: 217 in 1/52 Lambda= 0.168174 statistics sampled from 25608 (25674) to 25608 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.301), width: 16 Scan time: 4.950 The best scores are: opt bits E(85289) NP_542163 (OMIM: 615013) histone H2A type 1-H [Hom ( 128) 810 204.2 4.7e-53 NP_066408 (OMIM: 615012) histone H2A type 1 [Homo ( 130) 810 204.2 4.8e-53 NP_003501 (OMIM: 602788) histone H2A type 1 [Homo ( 130) 810 204.2 4.8e-53 NP_003502 (OMIM: 602793) histone H2A type 1 [Homo ( 130) 810 204.2 4.8e-53 NP_003505 (OMIM: 602796) histone H2A type 1 [Homo ( 130) 810 204.2 4.8e-53 NP_003500 (OMIM: 602787) histone H2A type 1 [Homo ( 130) 810 204.2 4.8e-53 NP_066409 (OMIM: 602792) histone H2A type 1-D [Hom ( 130) 806 203.2 9.3e-53 NP_066544 (OMIM: 602791) histone cluster 1, H2aj [ ( 128) 805 203.0 1.1e-52 NP_003507 (OMIM: 142720) histone H2A type 2-A [Hom ( 130) 805 203.0 1.1e-52 NP_003503 (OMIM: 602794) histone H2A type 1-C [Hom ( 130) 804 202.8 1.3e-52 NP_066390 (OMIM: 602786) histone H2A type 1-B/E [H ( 130) 803 202.5 1.5e-52 NP_003504 (OMIM: 602795) histone H2A type 1-B/E [H ( 130) 803 202.5 1.5e-52 NP_254280 (OMIM: 615015) histone H2A type 3 [Homo ( 130) 800 201.8 2.6e-52 NP_003508 (OMIM: 602797) histone H2A type 2-C [Hom ( 129) 783 197.7 4.4e-51 NP_778235 (OMIM: 615014) histone H2A type 2-B [Hom ( 130) 776 196.0 1.5e-50 NP_734466 (OMIM: 613499) histone H2A type 1-A [Hom ( 131) 773 195.2 2.4e-50 NP_002096 (OMIM: 601772) histone H2AX [Homo sapien ( 143) 737 186.5 1.1e-47 XP_011542037 (OMIM: 610054) PREDICTED: core histon ( 195) 493 127.4 9.5e-30 XP_011542036 (OMIM: 610054) PREDICTED: core histon ( 196) 493 127.4 9.5e-30 XP_005272192 (OMIM: 610054) PREDICTED: core histon ( 198) 493 127.4 9.6e-30 XP_005272191 (OMIM: 610054) PREDICTED: core histon ( 199) 493 127.4 9.6e-30 XP_016865558 (OMIM: 610054) PREDICTED: core histon ( 222) 493 127.4 1.1e-29 XP_016865557 (OMIM: 610054) PREDICTED: core histon ( 235) 493 127.5 1.1e-29 XP_016865556 (OMIM: 610054) PREDICTED: core histon ( 251) 493 127.5 1.2e-29 XP_011542035 (OMIM: 610054) PREDICTED: core histon ( 252) 493 127.5 1.2e-29 XP_011542034 (OMIM: 610054) PREDICTED: core histon ( 269) 493 127.5 1.2e-29 XP_011542033 (OMIM: 610054) PREDICTED: core histon ( 270) 493 127.5 1.2e-29 XP_005272189 (OMIM: 610054) PREDICTED: core histon ( 368) 493 127.6 1.6e-29 NP_613075 (OMIM: 610054) core histone macro-H2A.1 ( 369) 493 127.6 1.6e-29 NP_001035248 (OMIM: 610054) core histone macro-H2A ( 371) 493 127.6 1.6e-29 NP_004884 (OMIM: 610054) core histone macro-H2A.1 ( 371) 493 127.6 1.6e-29 XP_011542032 (OMIM: 610054) PREDICTED: core histon ( 371) 493 127.6 1.6e-29 NP_613258 (OMIM: 610054) core histone macro-H2A.1 ( 372) 493 127.6 1.6e-29 XP_011542031 (OMIM: 610054) PREDICTED: core histon ( 372) 493 127.6 1.6e-29 NP_061119 (OMIM: 616141) core histone macro-H2A.2 ( 372) 483 125.1 8.6e-29 NP_002097 (OMIM: 142763) histone H2A.Z [Homo sapie ( 128) 451 117.1 7.8e-27 NP_542451 (OMIM: 300445) histone H2A-Bbd type 2/3 ( 115) 299 80.2 9.1e-16 XP_011531366 (OMIM: 135300,182530,610733) PREDICTE (1276) 157 46.4 0.00015 XP_005264572 (OMIM: 135300,182530,610733) PREDICTE (1318) 157 46.4 0.00016 XP_011531364 (OMIM: 135300,182530,610733) PREDICTE (1326) 157 46.4 0.00016 NP_005624 (OMIM: 135300,182530,610733) son of seve (1333) 157 46.4 0.00016 NP_008870 (OMIM: 601247,616559) son of sevenless h (1332) 136 41.3 0.0054 >>NP_542163 (OMIM: 615013) histone H2A type 1-H [Homo sa (128 aa) initn: 810 init1: 810 opt: 810 Z-score: 1073.5 bits: 204.2 E(85289): 4.7e-53 Smith-Waterman score: 810; 100.0% identity (100.0% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 pF1KE0 TESHHKAK :::::::: NP_542 TESHHKAK >>NP_066408 (OMIM: 615012) histone H2A type 1 [Homo sapi (130 aa) initn: 810 init1: 810 opt: 810 Z-score: 1073.4 bits: 204.2 E(85289): 4.8e-53 Smith-Waterman score: 810; 100.0% identity (100.0% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 pF1KE0 TESHHKAK :::::::: NP_066 TESHHKAKGK 130 >>NP_003501 (OMIM: 602788) histone H2A type 1 [Homo sapi (130 aa) initn: 810 init1: 810 opt: 810 Z-score: 1073.4 bits: 204.2 E(85289): 4.8e-53 Smith-Waterman score: 810; 100.0% identity (100.0% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 pF1KE0 TESHHKAK :::::::: NP_003 TESHHKAKGK 130 >>NP_003502 (OMIM: 602793) histone H2A type 1 [Homo sapi (130 aa) initn: 810 init1: 810 opt: 810 Z-score: 1073.4 bits: 204.2 E(85289): 4.8e-53 Smith-Waterman score: 810; 100.0% identity (100.0% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 pF1KE0 TESHHKAK :::::::: NP_003 TESHHKAKGK 130 >>NP_003505 (OMIM: 602796) histone H2A type 1 [Homo sapi (130 aa) initn: 810 init1: 810 opt: 810 Z-score: 1073.4 bits: 204.2 E(85289): 4.8e-53 Smith-Waterman score: 810; 100.0% identity (100.0% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 pF1KE0 TESHHKAK :::::::: NP_003 TESHHKAKGK 130 >>NP_003500 (OMIM: 602787) histone H2A type 1 [Homo sapi (130 aa) initn: 810 init1: 810 opt: 810 Z-score: 1073.4 bits: 204.2 E(85289): 4.8e-53 Smith-Waterman score: 810; 100.0% identity (100.0% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 pF1KE0 TESHHKAK :::::::: NP_003 TESHHKAKGK 130 >>NP_066409 (OMIM: 602792) histone H2A type 1-D [Homo sa (130 aa) initn: 806 init1: 806 opt: 806 Z-score: 1068.1 bits: 203.2 E(85289): 9.3e-53 Smith-Waterman score: 806; 99.2% identity (100.0% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: NP_066 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 pF1KE0 TESHHKAK :::::::: NP_066 TESHHKAKGK 130 >>NP_066544 (OMIM: 602791) histone cluster 1, H2aj [Homo (128 aa) initn: 828 init1: 805 opt: 805 Z-score: 1066.9 bits: 203.0 E(85289): 1.1e-52 Smith-Waterman score: 805; 99.2% identity (100.0% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 pF1KE0 TESHHKAK ::::::.: NP_066 TESHHKTK >>NP_003507 (OMIM: 142720) histone H2A type 2-A [Homo sa (130 aa) initn: 805 init1: 805 opt: 805 Z-score: 1066.8 bits: 203.0 E(85289): 1.1e-52 Smith-Waterman score: 805; 98.4% identity (100.0% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT ::::::::::::::::.::::::::::::::::::::::::::::::::::.:::::::: NP_003 MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 pF1KE0 TESHHKAK :::::::: NP_003 TESHHKAKGK 130 >>NP_003503 (OMIM: 602794) histone H2A type 1-C [Homo sa (130 aa) initn: 804 init1: 804 opt: 804 Z-score: 1065.5 bits: 202.8 E(85289): 1.3e-52 Smith-Waterman score: 804; 98.4% identity (100.0% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: NP_003 MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: NP_003 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 pF1KE0 TESHHKAK :::::::: NP_003 TESHHKAKGK 130 128 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:32:30 2016 done: Thu Nov 3 20:32:31 2016 Total Scan time: 4.950 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]