FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0228, 110 aa 1>>>pF1KE0228 110 - 110 aa - 110 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7991+/-0.000664; mu= 12.2421+/- 0.040 mean_var=52.8878+/-10.508, 0's: 0 Z-trim(108.9): 31 B-trim: 0 in 0/51 Lambda= 0.176358 statistics sampled from 10490 (10515) to 10490 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.323), width: 16 Scan time: 1.580 The best scores are: opt bits E(32554) CCDS31662.1 CARD17 gene_id:440068|Hs108|chr11 ( 110) 702 185.8 4.7e-48 CCDS8330.1 CASP1 gene_id:834|Hs108|chr11 ( 404) 543 145.6 2.1e-35 CCDS41705.1 CARD16 gene_id:114769|Hs108|chr11 ( 97) 495 133.1 3e-32 CCDS8329.1 CASP1 gene_id:834|Hs108|chr11 ( 383) 487 131.4 3.9e-31 CCDS31661.1 CARD16 gene_id:114769|Hs108|chr11 ( 197) 464 125.4 1.3e-29 CCDS53705.1 CARD18 gene_id:59082|Hs108|chr11 ( 90) 302 84.0 1.7e-17 >>CCDS31662.1 CARD17 gene_id:440068|Hs108|chr11 (110 aa) initn: 702 init1: 702 opt: 702 Z-score: 976.3 bits: 185.8 E(32554): 4.7e-48 Smith-Waterman score: 702; 100.0% identity (100.0% similar) in 110 aa overlap (1-110:1-110) 10 20 30 40 50 60 pF1KE0 MADKVLKEKRKQFIRSVGEGTINGLLGELLETRVLSQEEIEIVKCENATVMDKARALLDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MADKVLKEKRKQFIRSVGEGTINGLLGELLETRVLSQEEIEIVKCENATVMDKARALLDS 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VIRKGAPACQICITYICEEDSHLAGTLGLSAGPTSGNHLTTQDSQIVLPS :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 VIRKGAPACQICITYICEEDSHLAGTLGLSAGPTSGNHLTTQDSQIVLPS 70 80 90 100 110 >>CCDS8330.1 CASP1 gene_id:834|Hs108|chr11 (404 aa) initn: 543 init1: 543 opt: 543 Z-score: 749.0 bits: 145.6 E(32554): 2.1e-35 Smith-Waterman score: 543; 80.9% identity (90.0% similar) in 110 aa overlap (1-110:1-110) 10 20 30 40 50 60 pF1KE0 MADKVLKEKRKQFIRSVGEGTINGLLGELLETRVLSQEEIEIVKCENATVMDKARALLDS ::::::::::: ::::.::::::::: :::.::::..::.: :: ::::::::.:::.:: CCDS83 MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDS 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VIRKGAPACQICITYICEEDSHLAGTLGLSAGPTSGNHLTTQDSQIVLPS :: ::: ::::::::::::::.::::::::: ::::.:. :::: :: : CCDS83 VIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDN 70 80 90 100 110 120 CCDS83 PAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRT 130 140 150 160 170 180 >>CCDS41705.1 CARD16 gene_id:114769|Hs108|chr11 (97 aa) initn: 495 init1: 495 opt: 495 Z-score: 692.4 bits: 133.1 E(32554): 3e-32 Smith-Waterman score: 495; 82.5% identity (90.7% similar) in 97 aa overlap (1-97:1-97) 10 20 30 40 50 60 pF1KE0 MADKVLKEKRKQFIRSVGEGTINGLLGELLETRVLSQEEIEIVKCENATVMDKARALLDS ::::::::::: ::.:.::::::::: :::.::::.:::.: :: ::::::::.:::.:: CCDS41 MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDS 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VIRKGAPACQICITYICEEDSHLAGTLGLSAGPTSGNHLTTQDSQIVLPS :: ::: ::::::::::::::.:: :::::::: :: CCDS41 VIPKGAQACQICITYICEEDSYLAETLGLSAGPIPGN 70 80 90 >>CCDS8329.1 CASP1 gene_id:834|Hs108|chr11 (383 aa) initn: 487 init1: 487 opt: 487 Z-score: 672.4 bits: 131.4 E(32554): 3.9e-31 Smith-Waterman score: 487; 83.9% identity (93.5% similar) in 93 aa overlap (1-93:1-93) 10 20 30 40 50 60 pF1KE0 MADKVLKEKRKQFIRSVGEGTINGLLGELLETRVLSQEEIEIVKCENATVMDKARALLDS ::::::::::: ::::.::::::::: :::.::::..::.: :: ::::::::.:::.:: CCDS83 MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDS 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VIRKGAPACQICITYICEEDSHLAGTLGLSAGPTSGNHLTTQDSQIVLPS :: ::: ::::::::::::::.:::::::::.: CCDS83 VIPKGAQACQICITYICEEDSYLAGTLGLSAAPQAVQDNPAMPTSSGSEGNVKLCSLEEA 70 80 90 100 110 120 CCDS83 QRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVD 130 140 150 160 170 180 >>CCDS31661.1 CARD16 gene_id:114769|Hs108|chr11 (197 aa) initn: 464 init1: 464 opt: 464 Z-score: 645.1 bits: 125.4 E(32554): 1.3e-29 Smith-Waterman score: 464; 83.5% identity (92.3% similar) in 91 aa overlap (1-91:1-91) 10 20 30 40 50 60 pF1KE0 MADKVLKEKRKQFIRSVGEGTINGLLGELLETRVLSQEEIEIVKCENATVMDKARALLDS ::::::::::: ::.:.::::::::: :::.::::.:::.: :: ::::::::.:::.:: CCDS31 MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDS 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VIRKGAPACQICITYICEEDSHLAGTLGLSAGPTSGNHLTTQDSQIVLPS :: ::: ::::::::::::::.:: :::::: CCDS31 VIPKGAQACQICITYICEEDSYLAETLGLSAALQAVQDNPAMPTCSSPEGRIKLCFLEDA 70 80 90 100 110 120 CCDS31 QRIWKQKLQRCHVQNTIIKWSERYTSGSFEMQWLFLRTNFIERFWRNILLLPLHKGSLYP 130 140 150 160 170 180 >>CCDS53705.1 CARD18 gene_id:59082|Hs108|chr11 (90 aa) initn: 302 init1: 302 opt: 302 Z-score: 427.6 bits: 84.0 E(32554): 1.7e-17 Smith-Waterman score: 302; 55.1% identity (78.7% similar) in 89 aa overlap (1-89:1-89) 10 20 30 40 50 60 pF1KE0 MADKVLKEKRKQFIRSVGEGTINGLLGELLETRVLSQEEIEIVKCENATVMDKARALLDS :::..:..::. ::.::: ::::.:: ::: .:.:::... :. :: :::::::.:.: CCDS53 MADQLLRKKRRIFIHSVGAGTINALLDCLLEDEVISQEDMNKVRDENDTVMDKARVLIDL 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 VIRKGAPACQICITYICEEDSHLAGTLGLSAGPTSGNHLTTQDSQIVLPS : :: .: : ..:::: .::. .:: CCDS53 VTGKGPKSCCKFIKHLCEEDPQLASKMGLH 70 80 90 110 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:29:12 2016 done: Thu Nov 3 20:29:13 2016 Total Scan time: 1.580 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]