FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0234, 254 aa 1>>>pF1KE0234 254 - 254 aa - 254 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9874+/-0.000656; mu= 11.9114+/- 0.040 mean_var=73.6577+/-14.860, 0's: 0 Z-trim(111.3): 9 B-trim: 48 in 1/51 Lambda= 0.149439 statistics sampled from 12237 (12246) to 12237 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.376), width: 16 Scan time: 1.860 The best scores are: opt bits E(32554) CCDS35338.1 PGAM4 gene_id:441531|Hs108|chrX ( 254) 1727 380.8 4.8e-106 CCDS7458.1 PGAM1 gene_id:5223|Hs108|chr10 ( 254) 1637 361.4 3.3e-100 CCDS34624.1 PGAM2 gene_id:5224|Hs108|chr7 ( 253) 1371 304.1 6e-83 CCDS5833.1 BPGM gene_id:669|Hs108|chr7 ( 259) 977 219.1 2.3e-57 >>CCDS35338.1 PGAM4 gene_id:441531|Hs108|chrX (254 aa) initn: 1727 init1: 1727 opt: 1727 Z-score: 2017.4 bits: 380.8 E(32554): 4.8e-106 Smith-Waterman score: 1727; 100.0% identity (100.0% similar) in 254 aa overlap (1-254:1-254) 10 20 30 40 50 60 pF1KE0 MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 VLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 VLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVC 190 200 210 220 230 240 250 pF1KE0 KAIEAVAAQGKAKK :::::::::::::: CCDS35 KAIEAVAAQGKAKK 250 >>CCDS7458.1 PGAM1 gene_id:5223|Hs108|chr10 (254 aa) initn: 1637 init1: 1637 opt: 1637 Z-score: 1912.5 bits: 361.4 E(32554): 3.3e-100 Smith-Waterman score: 1637; 95.7% identity (98.4% similar) in 254 aa overlap (1-254:1-254) 10 20 30 40 50 60 pF1KE0 MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ ::::::::::::::.:::::::: :::::::::::::::::::::::::::::::.:::: CCDS74 MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD ::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 KRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKR :::::::::::::::::::::::::::::::: :: :::::::::::::::::::::::: CCDS74 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 VLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVC ::::::::::.::.::.:::::::::::::::::::::::::::::::::::::::::: CCDS74 VLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVR 190 200 210 220 230 240 250 pF1KE0 KAIEAVAAQGKAKK ::.::::::::::: CCDS74 KAMEAVAAQGKAKK 250 >>CCDS34624.1 PGAM2 gene_id:5224|Hs108|chr7 (253 aa) initn: 1371 init1: 1371 opt: 1371 Z-score: 1602.6 bits: 304.1 E(32554): 6e-83 Smith-Waterman score: 1371; 77.9% identity (91.3% similar) in 253 aa overlap (1-253:1-253) 10 20 30 40 50 60 pF1KE0 MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ ::...::..:::::::: :::: :.::.:: : ::::::..:..:: .::::: ::: CCDS34 MATHRLVMVRHGESTWNQENRFCGWFDAELSEKGTEEAKRGAKAIKDAKMEFDICYTSVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD ::.:::::..::. ::::::::::::::::::::::::::::::::::: ::::::::.: CCDS34 KRAIRTLWAILDGTDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKR .:::::. ::.:..:::.:::: : .::. :: :::::::::::::::::::: ::: CCDS34 IPPPPMDEKHPYYNSISKERRYAGLKPGELPTCESLKDTIARALPFWNEEIVPQIKAGKR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 VLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVC ::::::::::.::.::.::.:..:::::::::::::::::.:.::: :::::::::::: CCDS34 VLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELNKELKPTKPMQFLGDEETVR 190 200 210 220 230 240 250 pF1KE0 KAIEAVAAQGKAKK ::.:::::::::: CCDS34 KAMEAVAAQGKAK 250 >>CCDS5833.1 BPGM gene_id:669|Hs108|chr7 (259 aa) initn: 979 init1: 577 opt: 977 Z-score: 1143.4 bits: 219.1 E(32554): 2.3e-57 Smith-Waterman score: 977; 52.0% identity (77.7% similar) in 256 aa overlap (1-254:1-256) 10 20 30 40 50 60 pF1KE0 MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ :. :::...::::..:: :::: : : :. : :::. :. :. ..:::. .::: CCDS58 MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD .: :.: : .:. . : :.:: .:::::::::.: :::. . : .::: ::..:::::. CCDS58 NRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYN 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 VPPPPMEPDHPFYSNISKDRRYA--DLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEG : :::.: .::.:..: .:::: :. :::: :: ::.. : ::.:::.:.:.. .: CCDS58 VTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 KRVLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEET : .::.::::: ... ::.::.:.: :....::::.::. :::.::. . : :::::.:. CCDS58 KTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEA 190 200 210 220 230 240 240 250 pF1KE0 VCKAIEAVAAQGKAKK . ::. : :::.:. CCDS58 IQAAIKKVEDQGKVKQAKK 250 254 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:06:42 2016 done: Thu Nov 3 20:06:42 2016 Total Scan time: 1.860 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]