FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0238, 162 aa 1>>>pF1KE0238 162 - 162 aa - 162 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1508+/-0.000765; mu= 12.1981+/- 0.046 mean_var=54.1921+/-10.813, 0's: 0 Z-trim(106.7): 19 B-trim: 0 in 0/46 Lambda= 0.174223 statistics sampled from 9106 (9118) to 9106 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.28), width: 16 Scan time: 1.860 The best scores are: opt bits E(32554) CCDS8046.1 HRASLS2 gene_id:54979|Hs108|chr11 ( 162) 1034 267.6 2.4e-72 CCDS8047.1 PLA2G16 gene_id:11145|Hs108|chr11 ( 162) 728 190.7 3.4e-49 CCDS41662.1 RARRES3 gene_id:5920|Hs108|chr11 ( 164) 527 140.2 5.6e-34 CCDS3303.2 HRASLS gene_id:57110|Hs108|chr3 ( 273) 467 125.2 3e-29 CCDS53646.1 HRASLS5 gene_id:117245|Hs108|chr11 ( 269) 457 122.6 1.7e-28 CCDS8044.1 HRASLS5 gene_id:117245|Hs108|chr11 ( 279) 457 122.6 1.8e-28 CCDS53647.1 HRASLS5 gene_id:117245|Hs108|chr11 ( 253) 351 96.0 1.7e-20 >>CCDS8046.1 HRASLS2 gene_id:54979|Hs108|chr11 (162 aa) initn: 1034 init1: 1034 opt: 1034 Z-score: 1412.4 bits: 267.6 E(32554): 2.4e-72 Smith-Waterman score: 1034; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162) 10 20 30 40 50 60 pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS80 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS80 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL 70 80 90 100 110 120 130 140 150 160 pF1KE0 RYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ :::::::::::::::::::::::::::::::::::::::::: CCDS80 RYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ 130 140 150 160 >>CCDS8047.1 PLA2G16 gene_id:11145|Hs108|chr11 (162 aa) initn: 729 init1: 709 opt: 728 Z-score: 996.7 bits: 190.7 E(32554): 3.4e-49 Smith-Waterman score: 728; 69.4% identity (89.8% similar) in 157 aa overlap (6-162:6-162) 10 20 30 40 50 60 pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV :.:. :::::: : : :::::::::::::::: ::.::::::::.::::.:::: CCDS80 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL ::::: :::.:.:.:::::::.:.::: .::..:::::::::. :.:::.:::::::.: CCDS80 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL 70 80 90 100 110 120 130 140 150 160 pF1KE0 RYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ ::::.::::: .. ...::. ::: ::.:....:.::..: CCDS80 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ 130 140 150 160 >>CCDS41662.1 RARRES3 gene_id:5920|Hs108|chr11 (164 aa) initn: 526 init1: 526 opt: 527 Z-score: 723.6 bits: 140.2 E(32554): 5.6e-34 Smith-Waterman score: 527; 55.7% identity (77.9% similar) in 149 aa overlap (1-147:1-149) 10 20 30 40 50 60 pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV :: . .:. :::::: :.:: :::.:.:::::.:::: :: :::..::.:.:.:.: : CCDS41 MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSAEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL :.: : :.:: :::::. : .: : : . :.. :.:.:::.. ::..: ::::::..: CCDS41 KRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVTQL 70 80 90 100 110 120 130 140 150 160 pF1KE0 RYGVSRSDQVTGAVTTVGVAA--GLLAAASLVGILLARSKRERQ ::: :: :: : . ::::. :.:..: CCDS41 RYGKSRCKQVEKAKVEVGVATALGILVVAGCSFAIRRYQKKATA 130 140 150 160 >>CCDS3303.2 HRASLS gene_id:57110|Hs108|chr3 (273 aa) initn: 473 init1: 310 opt: 467 Z-score: 638.5 bits: 125.2 E(32554): 3e-29 Smith-Waterman score: 467; 45.3% identity (78.9% similar) in 161 aa overlap (2-161:113-271) 10 20 30 pF1KE0 MALARP-RPRLGDLIEISRFGYAHWAIYVGD .: : : :::::. : :: :::.:.:: CCDS33 PRETPGHTQLPPGARRRPRLESEMAFNDCFSLNYPGNPCPGDLIEVFRPGYQHWALYLGD 90 100 110 120 130 140 40 50 60 70 80 90 pF1KE0 GYVVHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSN :::...::.. : :. .:. :....::.:: .::. :.:.:.::.:::.:. : ::: . CCDS33 GYVINIAPVDGIP-ASFTSAKSVFSSKALVKMQLLKDVVGNDTYRINNKYDETYPPLPVE 150 160 170 180 190 200 100 110 120 130 140 150 pF1KE0 KIVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLV .:.::.: ..:::. :.: .::::::. :::: . :.:.. :..:: ... ... :.. CCDS33 EIIKRSEFVIGQEVAYNLLVNNCEHFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFL 210 220 230 240 250 260 160 pF1KE0 GILLARSKRERQ : :. ...: . CCDS33 G-LFPKGQRAKYY 270 >>CCDS53646.1 HRASLS5 gene_id:117245|Hs108|chr11 (269 aa) initn: 425 init1: 249 opt: 457 Z-score: 625.0 bits: 122.6 E(32554): 1.7e-28 Smith-Waterman score: 457; 52.1% identity (70.5% similar) in 146 aa overlap (2-147:114-257) 10 20 30 pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDG : ..:::: :::::: :.:: :::::: : CCDS53 VVSLETTPSQKADWSSIPKPENEGKLIKQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDD 90 100 110 120 130 140 40 50 60 70 80 90 pF1KE0 YVVHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNK :::::: :: .: :. : ..:.:.:: : : : ...:::: : : ::: .: CCDS53 CVVHLAPPSEEFEVG--SITSIFSNRAVVKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDK 150 160 170 180 190 200 100 110 120 130 140 150 pF1KE0 IVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVG :..:....:.. . ::: ::::::: ::::: ::.:: :. . ::: . .: CCDS53 IIQRTKKMVNKIVQYSLIEGNCEHFVNGLRYGVPRSQQVEHALMEGAKAAGAVISAVVDS 210 220 230 240 250 260 160 pF1KE0 ILLARSKRERQ CCDS53 IKPKPITA >>CCDS8044.1 HRASLS5 gene_id:117245|Hs108|chr11 (279 aa) initn: 425 init1: 249 opt: 457 Z-score: 624.7 bits: 122.6 E(32554): 1.8e-28 Smith-Waterman score: 457; 52.1% identity (70.5% similar) in 146 aa overlap (2-147:124-267) 10 20 30 pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDG : ..:::: :::::: :.:: :::::: : CCDS80 VVSLETTPSQKADWSSIPKPENEGKLIKQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDD 100 110 120 130 140 150 40 50 60 70 80 90 pF1KE0 YVVHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNK :::::: :: .: :. : ..:.:.:: : : : ...:::: : : ::: .: CCDS80 CVVHLAPPSEEFEVG--SITSIFSNRAVVKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDK 160 170 180 190 200 210 100 110 120 130 140 150 pF1KE0 IVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVG :..:....:.. . ::: ::::::: ::::: ::.:: :. . ::: . .: CCDS80 IIQRTKKMVNKIVQYSLIEGNCEHFVNGLRYGVPRSQQVEHALMEGAKAAGAVISAVVDS 220 230 240 250 260 270 160 pF1KE0 ILLARSKRERQ CCDS80 IKPKPITA >>CCDS53647.1 HRASLS5 gene_id:117245|Hs108|chr11 (253 aa) initn: 353 init1: 190 opt: 351 Z-score: 481.4 bits: 96.0 E(32554): 1.7e-20 Smith-Waterman score: 351; 50.9% identity (70.5% similar) in 112 aa overlap (2-113:124-233) 10 20 30 pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDG : ..:::: :::::: :.:: :::::: : CCDS53 VVSLETTPSQKADWSSIPKPENEGKLIKQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDD 100 110 120 130 140 150 40 50 60 70 80 90 pF1KE0 YVVHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNK :::::: :: .: :. : ..:.:.:: : : : ...:::: : : ::: .: CCDS53 CVVHLAPPSEEFEVG--SITSIFSNRAVVKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDK 160 170 180 190 200 210 100 110 120 130 140 150 pF1KE0 IVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVG :..:....:.. . ::: :: CCDS53 IIQRTKKMVNKIVQYSLIEGNCRARPDGRSEGCWSSYFSCSG 220 230 240 250 162 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 19:53:32 2016 done: Thu Nov 3 19:53:33 2016 Total Scan time: 1.860 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]