FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0245, 240 aa 1>>>pF1KE0245 240 - 240 aa - 240 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7355+/-0.000658; mu= 17.2725+/- 0.040 mean_var=60.0661+/-12.386, 0's: 0 Z-trim(109.9): 16 B-trim: 515 in 1/48 Lambda= 0.165485 statistics sampled from 11211 (11227) to 11211 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.345), width: 16 Scan time: 2.430 The best scores are: opt bits E(32554) CCDS12171.1 TNFSF14 gene_id:8740|Hs108|chr19 ( 240) 1611 392.5 1.3e-109 CCDS45939.1 TNFSF14 gene_id:8740|Hs108|chr19 ( 204) 1126 276.6 8.4e-75 CCDS1304.1 FASLG gene_id:356|Hs108|chr1 ( 281) 295 78.3 5.7e-15 >>CCDS12171.1 TNFSF14 gene_id:8740|Hs108|chr19 (240 aa) initn: 1611 init1: 1611 opt: 1611 Z-score: 2081.2 bits: 392.5 E(32554): 1.3e-109 Smith-Waterman score: 1611; 100.0% identity (100.0% similar) in 240 aa overlap (1-240:1-240) 10 20 30 40 50 60 pF1KE0 MEESVVRPSVFVVDGQTDIPFTRLGRSHRRQSCSVARVGLGLLLLLMGAGLAVQGWFLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MEESVVRPSVFVVDGQTDIPFTRLGRSHRRQSCSVARVGLGLLLLLMGAGLAVQGWFLLQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LHWRLGEMVTRLPDGPAGSWEQLIQERRSHEVNPAAHLTGANSSLTGSGGPLLWETQLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LHWRLGEMVTRLPDGPAGSWEQLIQERRSHEVNPAAHLTGANSSLTGSGGPLLWETQLGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AFLRGLSYHDGALVVTKAGYYYIYSKVQLGGVGCPLGLASTITHGLYKRTPRYPEELELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 AFLRGLSYHDGALVVTKAGYYYIYSKVQLGGVGCPLGLASTITHGLYKRTPRYPEELELL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 VSQQSPCGRATSSSRVWWDSSFLGGVVHLEAGEKVVVRVLDERLVRLRDGTRSYFGAFMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 VSQQSPCGRATSSSRVWWDSSFLGGVVHLEAGEKVVVRVLDERLVRLRDGTRSYFGAFMV 190 200 210 220 230 240 >>CCDS45939.1 TNFSF14 gene_id:8740|Hs108|chr19 (204 aa) initn: 1121 init1: 1121 opt: 1126 Z-score: 1456.4 bits: 276.6 E(32554): 8.4e-75 Smith-Waterman score: 1285; 85.0% identity (85.0% similar) in 240 aa overlap (1-240:1-204) 10 20 30 40 50 60 pF1KE0 MEESVVRPSVFVVDGQTDIPFTRLGRSHRRQSCSVARVGLGLLLLLMGAGLAVQGWFLLQ ::::::::::::::::::::::::::::::::::::: CCDS45 MEESVVRPSVFVVDGQTDIPFTRLGRSHRRQSCSVAR----------------------- 10 20 30 70 80 90 100 110 120 pF1KE0 LHWRLGEMVTRLPDGPAGSWEQLIQERRSHEVNPAAHLTGANSSLTGSGGPLLWETQLGL ::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 -------------DGPAGSWEQLIQERRSHEVNPAAHLTGANSSLTGSGGPLLWETQLGL 40 50 60 70 80 130 140 150 160 170 180 pF1KE0 AFLRGLSYHDGALVVTKAGYYYIYSKVQLGGVGCPLGLASTITHGLYKRTPRYPEELELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 AFLRGLSYHDGALVVTKAGYYYIYSKVQLGGVGCPLGLASTITHGLYKRTPRYPEELELL 90 100 110 120 130 140 190 200 210 220 230 240 pF1KE0 VSQQSPCGRATSSSRVWWDSSFLGGVVHLEAGEKVVVRVLDERLVRLRDGTRSYFGAFMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VSQQSPCGRATSSSRVWWDSSFLGGVVHLEAGEKVVVRVLDERLVRLRDGTRSYFGAFMV 150 160 170 180 190 200 >>CCDS1304.1 FASLG gene_id:356|Hs108|chr1 (281 aa) initn: 196 init1: 146 opt: 295 Z-score: 382.2 bits: 78.3 E(32554): 5.7e-15 Smith-Waterman score: 295; 29.2% identity (62.8% similar) in 226 aa overlap (20-238:70-279) 10 20 30 40 pF1KE0 MEESVVRPSVFVVDGQTDIPFTRLGRSHRRQSCSVARVGLGLLLLLMGA :. . : .: : .. . .:. :.: CCDS13 PGQRRPPPPPPPPPLPPPPPPPPLPPLPLPPLKKRG-NHSTGLCLLVMFFM-VLVALVGL 40 50 60 70 80 90 50 60 70 80 90 100 pF1KE0 GLAVQGWF-LLQLHWRLGEMVTRLPD-GPAGSWEQLIQER----RSHEVNPAAHLTGANS :: : : :..:. .:.:. . :.: :. : . ...:. .::::: .. CCDS13 GL---GMFQLFHLQKELAELRESTSQMHTASSLEKQIGHPSPPPEKKELRKVAHLTGKSN 100 110 120 130 140 150 110 120 130 140 150 160 pF1KE0 SLTGSGGPLLWETQLGLAFLRGLSYHDGALVVTKAGYYYIYSKVQLGGVGCPLGLASTIT : . :: :: :...: :..:. :.::....: :..:::: . : .: .. CCDS13 SRSM---PLEWEDTYGIVLLSGVKYKKGGLVINETGLYFVYSKVYFRGQSCN---NLPLS 160 170 180 190 200 170 180 190 200 210 220 pF1KE0 HGLYKRTPRYPEELELLVSQQ-SPCGRATSSSRVWWDSSFLGGVVHLEAGEKVVVRVLDE : .: :. .::..: .. ... : : .....: ::.::.: .: ..... : : . CCDS13 HKVYMRNSKYPQDLVMMEGKMMSYC----TTGQMWARSSYLGAVFNLTSADHLYVNVSEL 210 220 230 240 250 260 230 240 pF1KE0 RLVRLRDGTRSYFGAFMV :: ... ....:: . CCDS13 SLVNFEE-SQTFFGLYKL 270 280 240 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 19:31:05 2016 done: Thu Nov 3 19:31:05 2016 Total Scan time: 2.430 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]