FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0256, 399 aa 1>>>pF1KE0256 399 - 399 aa - 399 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9998+/-0.000369; mu= 18.3782+/- 0.023 mean_var=61.0264+/-12.408, 0's: 0 Z-trim(111.5): 45 B-trim: 0 in 0/51 Lambda= 0.164178 statistics sampled from 20013 (20058) to 20013 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.587), E-opt: 0.2 (0.235), width: 16 Scan time: 7.760 The best scores are: opt bits E(85289) XP_011538379 (OMIM: 613922) PREDICTED: lipase memb ( 399) 2742 658.2 9.7e-189 NP_001073987 (OMIM: 613922) lipase member K precur ( 399) 2742 658.2 9.7e-189 XP_011538377 (OMIM: 613922) PREDICTED: lipase memb ( 408) 2742 658.2 9.9e-189 XP_011538375 (OMIM: 613922) PREDICTED: lipase memb ( 419) 2742 658.2 1e-188 XP_016872037 (OMIM: 613922) PREDICTED: lipase memb ( 358) 2039 491.7 1.2e-138 XP_016872034 (OMIM: 613922) PREDICTED: lipase memb ( 395) 2030 489.6 5.6e-138 XP_016872035 (OMIM: 613922) PREDICTED: lipase memb ( 386) 1984 478.7 1.1e-134 NP_004181 (OMIM: 601980) gastric triacylglycerol l ( 398) 1800 435.1 1.4e-121 XP_011538613 (OMIM: 601980) PREDICTED: gastric tri ( 398) 1800 435.1 1.4e-121 NP_001185758 (OMIM: 601980) gastric triacylglycero ( 408) 1800 435.1 1.5e-121 XP_011538384 (OMIM: 613922) PREDICTED: lipase memb ( 265) 1738 420.3 2.7e-117 NP_001121077 (OMIM: 278000,613497) lysosomal acid ( 399) 1578 382.5 9.6e-106 NP_000226 (OMIM: 278000,613497) lysosomal acid lip ( 399) 1578 382.5 9.6e-106 XP_006717698 (OMIM: 613921) PREDICTED: lipase memb ( 366) 1547 375.2 1.5e-103 XP_011537617 (OMIM: 613921) PREDICTED: lipase memb ( 366) 1547 375.2 1.5e-103 XP_011537616 (OMIM: 613921) PREDICTED: lipase memb ( 366) 1547 375.2 1.5e-103 NP_001010939 (OMIM: 613921) lipase member J [Homo ( 366) 1547 375.2 1.5e-103 XP_016872036 (OMIM: 613922) PREDICTED: lipase memb ( 370) 1519 368.5 1.5e-101 NP_001121687 (OMIM: 613923) lipase member M precur ( 423) 1473 357.7 3.1e-98 XP_011538050 (OMIM: 613923) PREDICTED: lipase memb ( 430) 1449 352.0 1.6e-96 XP_011538386 (OMIM: 613924,613943) PREDICTED: lipa ( 398) 1445 351.0 2.9e-96 NP_001095939 (OMIM: 613924,613943) lipase member N ( 398) 1445 351.0 2.9e-96 XP_005270106 (OMIM: 613924,613943) PREDICTED: lipa ( 398) 1445 351.0 2.9e-96 XP_011538385 (OMIM: 613924,613943) PREDICTED: lipa ( 398) 1445 351.0 2.9e-96 NP_001185757 (OMIM: 601980) gastric triacylglycero ( 365) 1368 332.8 8.4e-91 NP_001185759 (OMIM: 601980) gastric triacylglycero ( 375) 1368 332.8 8.6e-91 XP_016871229 (OMIM: 613921) PREDICTED: lipase memb ( 315) 1298 316.1 7.3e-86 NP_001275908 (OMIM: 278000,613497) lysosomal acid ( 283) 1160 283.4 4.6e-76 XP_011538053 (OMIM: 613923) PREDICTED: lipase memb ( 302) 1052 257.9 2.4e-68 XP_005269599 (OMIM: 613921) PREDICTED: lipase memb ( 253) 985 241.9 1.3e-63 XP_011538387 (OMIM: 613924,613943) PREDICTED: lipa ( 374) 964 237.1 5.5e-62 XP_011538388 (OMIM: 613924,613943) PREDICTED: lipa ( 350) 956 235.2 1.9e-61 XP_011538055 (OMIM: 613923) PREDICTED: lipase memb ( 238) 887 218.7 1.2e-56 XP_011537619 (OMIM: 613921) PREDICTED: lipase memb ( 317) 866 213.8 4.7e-55 XP_016872038 (OMIM: 613924,613943) PREDICTED: lipa ( 244) 845 208.8 1.2e-53 XP_011537620 (OMIM: 613921) PREDICTED: lipase memb ( 225) 829 205.0 1.5e-52 XP_011538054 (OMIM: 613923) PREDICTED: lipase memb ( 240) 738 183.4 5e-46 XP_011537621 (OMIM: 613921) PREDICTED: lipase memb ( 184) 692 172.5 7.6e-43 XP_011537622 (OMIM: 613921) PREDICTED: lipase memb ( 184) 692 172.5 7.6e-43 >>XP_011538379 (OMIM: 613922) PREDICTED: lipase member K (399 aa) initn: 2742 init1: 2742 opt: 2742 Z-score: 3509.4 bits: 658.2 E(85289): 9.7e-189 Smith-Waterman score: 2742; 100.0% identity (100.0% similar) in 399 aa overlap (1-399:1-399) 10 20 30 40 50 60 pF1KE0 MWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIISYWGYPYEEYDVTTKDGYILG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIISYWGYPYEEYDVTTKDGYILG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 NTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVGHSQGTTIAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVGHSQGTTIAFI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 AFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRRVVKVLFGDKMFHPHTLFDQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRRVVKVLFGDKMFHPHTLFDQF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 IATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNMLHWAQAVNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNMLHWAQAVNS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 GQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKDVENLLPQIAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKDVENLLPQIAN 310 320 330 340 350 360 370 380 390 pF1KE0 LIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN ::::::::::::::::::::::::::::::::::::::: XP_011 LIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN 370 380 390 >>NP_001073987 (OMIM: 613922) lipase member K precursor (399 aa) initn: 2742 init1: 2742 opt: 2742 Z-score: 3509.4 bits: 658.2 E(85289): 9.7e-189 Smith-Waterman score: 2742; 100.0% identity (100.0% similar) in 399 aa overlap (1-399:1-399) 10 20 30 40 50 60 pF1KE0 MWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIISYWGYPYEEYDVTTKDGYILG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIISYWGYPYEEYDVTTKDGYILG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 NTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVGHSQGTTIAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVGHSQGTTIAFI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 AFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRRVVKVLFGDKMFHPHTLFDQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRRVVKVLFGDKMFHPHTLFDQF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 IATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNMLHWAQAVNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNMLHWAQAVNS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 GQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKDVENLLPQIAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKDVENLLPQIAN 310 320 330 340 350 360 370 380 390 pF1KE0 LIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN ::::::::::::::::::::::::::::::::::::::: NP_001 LIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN 370 380 390 >>XP_011538377 (OMIM: 613922) PREDICTED: lipase member K (408 aa) initn: 2742 init1: 2742 opt: 2742 Z-score: 3509.3 bits: 658.2 E(85289): 9.9e-189 Smith-Waterman score: 2742; 100.0% identity (100.0% similar) in 399 aa overlap (1-399:10-408) 10 20 30 40 50 pF1KE0 MWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIISYWGYPYEEYDV ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MESLLGRSQMWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIISYWGYPYEEYDV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 TTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNNSLAFLLADSGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNNSLAFLLADSGY 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 DVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVGH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 SQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRRVVKVLFGDKMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRRVVKVLFGDKMF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 HPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNM 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE0 LHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKDV 310 320 330 340 350 360 360 370 380 390 pF1KE0 ENLLPQIANLIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENLLPQIANLIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN 370 380 390 400 >>XP_011538375 (OMIM: 613922) PREDICTED: lipase member K (419 aa) initn: 2742 init1: 2742 opt: 2742 Z-score: 3509.1 bits: 658.2 E(85289): 1e-188 Smith-Waterman score: 2742; 100.0% identity (100.0% similar) in 399 aa overlap (1-399:21-419) 10 20 30 40 pF1KE0 MWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIIS :::::::::::::::::::::::::::::::::::::::: XP_011 MHLKLPGLEDRPPKTWIRSQMWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIIS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 YWGYPYEEYDVTTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YWGYPYEEYDVTTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNN 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 SLAFLLADSGYDVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLAFLLADSGYDVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEK 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 TGQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRR 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE0 VVKVLFGDKMFHPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVKVLFGDKMFHPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE0 HNPAGTSVQNMLHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HNPAGTSVQNMLHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNG 310 320 330 340 350 360 350 360 370 380 390 pF1KE0 GQDIVADPKDVENLLPQIANLIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQDIVADPKDVENLLPQIANLIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN 370 380 390 400 410 >>XP_016872037 (OMIM: 613922) PREDICTED: lipase member K (358 aa) initn: 2057 init1: 2036 opt: 2039 Z-score: 2610.2 bits: 491.7 E(85289): 1.2e-138 Smith-Waterman score: 2039; 92.4% identity (94.8% similar) in 328 aa overlap (1-325:21-341) 10 20 30 40 pF1KE0 MWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIIS :::::::::::::::::::::::::::::::::::::::: XP_016 MHLKLPGLEDRPPKTWIRSQMWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIIS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 YWGYPYEEYDVTTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YWGYPYEEYDVTTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNN 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 SLAFLLADSGYDVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLAFLLADSGYDVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEK 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 TGQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRR 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE0 VVKVLFGDKMFHPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVKVLFGDKMFHPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLS 250 260 270 280 290 300 290 300 310 320 330 pF1KE0 HNPAGTSVQNMLHWAQAVNSGQLQAFDWGNSDQNMMHF---HQLTPPLYNITKMEVPTAI :::::::::::::::: : :.. . .:::. . . ::. XP_016 HNPAGTSVQNMLHWAQKVISSNRTLY-------KMMHLIPERAVHPPINIWGISECGNDA 310 320 330 340 350 340 350 360 370 380 390 pF1KE0 WNGGQDIVADPKDVENLLPQIANLIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYL XP_016 LFRED >>XP_016872034 (OMIM: 613922) PREDICTED: lipase member K (395 aa) initn: 2030 init1: 2030 opt: 2030 Z-score: 2598.1 bits: 489.6 E(85289): 5.6e-138 Smith-Waterman score: 2508; 94.0% identity (94.0% similar) in 399 aa overlap (1-399:21-395) 10 20 30 40 pF1KE0 MWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIIS :::::::::::::::::::::::::::::::::::::::: XP_016 MHLKLPGLEDRPPKTWIRSQMWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIIS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 YWGYPYEEYDVTTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YWGYPYEEYDVTTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNN 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 SLAFLLADSGYDVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLAFLLADSGYDVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEK 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 TGQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRR 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE0 VVKVLFGDKMFHPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVKVLFGDKMFHPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE0 HNPAGTSVQNMLHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNG :::::::::::::::: :::::::::::::::::::: XP_016 HNPAGTSVQNMLHWAQ------------------------LTPPLYNITKMEVPTAIWNG 310 320 330 350 360 370 380 390 pF1KE0 GQDIVADPKDVENLLPQIANLIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQDIVADPKDVENLLPQIANLIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN 340 350 360 370 380 390 >>XP_016872035 (OMIM: 613922) PREDICTED: lipase member K (386 aa) initn: 1984 init1: 1984 opt: 1984 Z-score: 2539.3 bits: 478.7 E(85289): 1.1e-134 Smith-Waterman score: 2443; 91.7% identity (91.7% similar) in 399 aa overlap (1-399:21-386) 10 20 30 40 pF1KE0 MWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIIS :::::::::::::::::::::::::::::::::::::::: XP_016 MHLKLPGLEDRPPKTWIRSQMWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIIS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 YWGYPYEEYDVTTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNN :::::::::::::::::::::::::::::::::: XP_016 YWGYPYEEYDVTTKDGYILGIYRIPHGRGCPGRT-------------------------- 70 80 90 110 120 130 140 150 160 pF1KE0 SLAFLLADSGYDVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEK ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 -------DSGYDVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEK 100 110 120 130 140 170 180 190 200 210 220 pF1KE0 TGQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRR 150 160 170 180 190 200 230 240 250 260 270 280 pF1KE0 VVKVLFGDKMFHPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVKVLFGDKMFHPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLS 210 220 230 240 250 260 290 300 310 320 330 340 pF1KE0 HNPAGTSVQNMLHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HNPAGTSVQNMLHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNG 270 280 290 300 310 320 350 360 370 380 390 pF1KE0 GQDIVADPKDVENLLPQIANLIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQDIVADPKDVENLLPQIANLIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN 330 340 350 360 370 380 >>NP_004181 (OMIM: 601980) gastric triacylglycerol lipas (398 aa) initn: 1825 init1: 1800 opt: 1800 Z-score: 2303.6 bits: 435.1 E(85289): 1.4e-121 Smith-Waterman score: 1800; 63.0% identity (85.1% similar) in 395 aa overlap (1-395:1-395) 10 20 30 40 50 60 pF1KE0 MWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIISYWGYPYEEYDVTTKDGYILG :: ::. : . .::. .: : . ..::..:::::.:.::::: :::.:.:.::::: NP_004 MWLLLTMASLISVLGTTHGLFGKLHPGSPEVTMNISQMITYWGYPNEEYEVVTEDGYILE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRG . :::.:. : :. .:.:.:::::.:::.::: :::::::::.:::.::::::::::: NP_004 VNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGNSRG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 NTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVGHSQGTTIAFI :::.:..: :: : :.::::.::::::::::::.::..:::::.:.::::::::::.:: NP_004 NTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQKQLHYVGHSQGTTIGFI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 AFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRRVVKVLFGDKMFHPHTLFDQF :::::: :::.:: :.:::::.:::::.: ..:: . . . : .::::.:.::..:::: NP_004 AFSTNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVPQSLFKFIFGDKIFYPHNFFDQF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 IATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNMLHWAQAVNS .::.::.:... .::: :: . ::: .:.: :::::::::::::::::::.::.:::.: NP_004 LATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAVKS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 GQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKDVENLLPQIAN :..::.:::. :: ::. : :: ::.: :.:: :.::::.:..:::.:: :::.. : NP_004 GKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPKLPN 310 320 330 340 350 360 370 380 390 pF1KE0 LIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN :::.: :: :::.:: . :::::.:.:.. .. : NP_004 LIYHKEIPFYNHLDFIWAMDAPQEVYNDIVSMISEDKK 370 380 390 >>XP_011538613 (OMIM: 601980) PREDICTED: gastric triacyl (398 aa) initn: 1825 init1: 1800 opt: 1800 Z-score: 2303.6 bits: 435.1 E(85289): 1.4e-121 Smith-Waterman score: 1800; 63.0% identity (85.1% similar) in 395 aa overlap (1-395:1-395) 10 20 30 40 50 60 pF1KE0 MWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIISYWGYPYEEYDVTTKDGYILG :: ::. : . .::. .: : . ..::..:::::.:.::::: :::.:.:.::::: XP_011 MWLLLTMASLISVLGTTHGLFGKLHPGSPEVTMNISQMITYWGYPNEEYEVVTEDGYILE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRG . :::.:. : :. .:.:.:::::.:::.::: :::::::::.:::.::::::::::: XP_011 VNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGNSRG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 NTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVGHSQGTTIAFI :::.:..: :: : :.::::.::::::::::::.::..:::::.:.::::::::::.:: XP_011 NTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQKQLHYVGHSQGTTIGFI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 AFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRRVVKVLFGDKMFHPHTLFDQF :::::: :::.:: :.:::::.:::::.: ..:: . . . : .::::.:.::..:::: XP_011 AFSTNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVPQSLFKFIFGDKIFYPHNFFDQF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 IATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNMLHWAQAVNS .::.::.:... .::: :: . ::: .:.: :::::::::::::::::::.::.:::.: XP_011 LATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAVKS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 GQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKDVENLLPQIAN :..::.:::. :: ::. : :: ::.: :.:: :.::::.:..:::.:: :::.. : XP_011 GKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPKLPN 310 320 330 340 350 360 370 380 390 pF1KE0 LIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN :::.: :: :::.:: . :::::.:.:.. .. : XP_011 LIYHKEIPFYNHLDFIWAMDAPQEVYNDIVSMISEDKK 370 380 390 >>NP_001185758 (OMIM: 601980) gastric triacylglycerol li (408 aa) initn: 1825 init1: 1800 opt: 1800 Z-score: 2303.5 bits: 435.1 E(85289): 1.5e-121 Smith-Waterman score: 1800; 63.0% identity (85.1% similar) in 395 aa overlap (1-395:11-405) 10 20 30 40 50 pF1KE0 MWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIISYWGYPYEEYD :: ::. : . .::. .: : . ..::..:::::.:.::::: :::. NP_001 MFSNANSRSKMWLLLTMASLISVLGTTHGLFGKLHPGSPEVTMNISQMITYWGYPNEEYE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 VTTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNNSLAFLLADSG :.:.::::: . :::.:. : :. .:.:.:::::.:::.::: :::::::::.:::.: NP_001 VVTEDGYILEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 YDVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVG :::::::::::::.:..: :: : :.::::.::::::::::::.::..:::::.:.::: NP_001 YDVWLGNSRGNTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQKQLHYVG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 HSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRRVVKVLFGDKM :::::::.:::::::: :::.:: :.:::::.:::::.: ..:: . . . : .::::. NP_001 HSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVPQSLFKFIFGDKI 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 FHPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQN :.::..::::.::.::.:... .::: :: . ::: .:.: :::::::::::::::::: NP_001 FYPHNFFDQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQN 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE0 MLHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKD :.::.:::.::..::.:::. :: ::. : :: ::.: :.:: :.::::.:..:::.: NP_001 MFHWTQAVKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQD 310 320 330 340 350 360 360 370 380 390 pF1KE0 VENLLPQIANLIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN : :::.. ::::.: :: :::.:: . :::::.:.:.. .. : NP_001 VGLLLPKLPNLIYHKEIPFYNHLDFIWAMDAPQEVYNDIVSMISEDKK 370 380 390 400 399 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:51:28 2016 done: Thu Nov 3 18:51:30 2016 Total Scan time: 7.760 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]