FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0259, 250 aa 1>>>pF1KE0259 250 - 250 aa - 250 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8851+/-0.000378; mu= 13.7566+/- 0.023 mean_var=167.7009+/-35.526, 0's: 0 Z-trim(118.1): 192 B-trim: 1327 in 1/57 Lambda= 0.099039 statistics sampled from 30449 (30770) to 30449 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.361), width: 16 Scan time: 6.740 The best scores are: opt bits E(85289) NP_944606 (OMIM: 612549) tripartite motif-containi ( 250) 1739 260.1 2.7e-69 NP_001304744 (OMIM: 612550) tripartite motif-conta ( 250) 1729 258.7 7.2e-69 XP_011514489 (OMIM: 612550) PREDICTED: tripartite ( 250) 1729 258.7 7.2e-69 NP_942150 (OMIM: 612550) tripartite motif-containi ( 250) 1729 258.7 7.2e-69 XP_011514491 (OMIM: 612550) PREDICTED: tripartite ( 249) 1711 256.1 4.3e-68 XP_011514089 (OMIM: 612548) PREDICTED: E3 ubiquiti ( 304) 1578 237.2 2.5e-62 NP_001268380 (OMIM: 612548) E3 ubiquitin-protein l ( 487) 1578 237.5 3.3e-62 NP_835226 (OMIM: 612548) E3 ubiquitin-protein liga ( 487) 1578 237.5 3.3e-62 XP_011514091 (OMIM: 612548) PREDICTED: E3 ubiquiti ( 486) 1566 235.8 1.1e-61 NP_001268379 (OMIM: 612548) E3 ubiquitin-protein l ( 486) 1566 235.8 1.1e-61 XP_011514492 (OMIM: 612550) PREDICTED: tripartite ( 228) 1335 202.3 6.1e-52 NP_001008275 (OMIM: 613288) tripartite motif-conta ( 477) 387 67.3 5.6e-11 NP_006501 (OMIM: 602165) zinc finger protein RFP [ ( 513) 360 63.5 8.4e-10 XP_016873952 (OMIM: 608487) PREDICTED: tripartite ( 265) 344 60.8 2.8e-09 XP_006718421 (OMIM: 608487) PREDICTED: tripartite ( 265) 344 60.8 2.8e-09 XP_011518729 (OMIM: 608487) PREDICTED: tripartite ( 271) 344 60.8 2.8e-09 NP_742013 (OMIM: 605700) E3 ubiquitin-protein liga ( 488) 347 61.6 3e-09 XP_016873951 (OMIM: 608487) PREDICTED: tripartite ( 300) 344 60.9 3e-09 XP_016873950 (OMIM: 608487) PREDICTED: tripartite ( 310) 344 60.9 3.1e-09 XP_011518728 (OMIM: 608487) PREDICTED: tripartite ( 310) 344 60.9 3.1e-09 NP_067076 (OMIM: 605700) E3 ubiquitin-protein liga ( 518) 347 61.6 3.1e-09 XP_016873949 (OMIM: 608487) PREDICTED: tripartite ( 314) 344 60.9 3.1e-09 NP_149084 (OMIM: 608487) tripartite motif-containi ( 326) 344 60.9 3.1e-09 XP_005253241 (OMIM: 608487) PREDICTED: tripartite ( 326) 344 60.9 3.1e-09 NP_149083 (OMIM: 608487) tripartite motif-containi ( 347) 344 61.0 3.3e-09 XP_005253240 (OMIM: 608487) PREDICTED: tripartite ( 493) 344 61.2 4e-09 NP_149023 (OMIM: 608487) tripartite motif-containi ( 493) 344 61.2 4e-09 NP_741983 (OMIM: 617007) tripartite motif-containi ( 493) 332 59.5 1.3e-08 XP_005273509 (OMIM: 617007) PREDICTED: tripartite ( 298) 322 57.7 2.6e-08 NP_660215 (OMIM: 607868) E3 ubiquitin-protein liga ( 468) 315 57.0 6.9e-08 XP_016857901 (OMIM: 607868) PREDICTED: E3 ubiquiti ( 467) 307 55.9 1.5e-07 NP_003132 (OMIM: 109092) E3 ubiquitin-protein liga ( 475) 304 55.4 2.1e-07 NP_001291424 (OMIM: 617007) tripartite motif-conta ( 266) 299 54.4 2.4e-07 XP_016857118 (OMIM: 616755) PREDICTED: E3 ubiquiti ( 555) 297 54.5 4.5e-07 XP_011542587 (OMIM: 607868) PREDICTED: E3 ubiquiti ( 391) 294 53.9 4.9e-07 NP_060677 (OMIM: 616755) E3 ubiquitin-protein liga ( 475) 287 53.0 1.1e-06 XP_011514090 (OMIM: 612548) PREDICTED: E3 ubiquiti ( 278) 262 49.1 9.6e-06 XP_011512568 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 261) 260 48.8 1.1e-05 XP_011512567 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 421) 260 49.1 1.5e-05 XP_011512566 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 424) 260 49.1 1.5e-05 NP_008959 (OMIM: 609316) E3 ubiquitin-protein liga ( 425) 260 49.1 1.5e-05 NP_892030 (OMIM: 616017) E3 ubiquitin-protein liga ( 500) 250 47.8 4.5e-05 NP_065091 (OMIM: 606124) tripartite motif-containi ( 452) 248 47.4 5.1e-05 NP_569074 (OMIM: 605684) tripartite motif-containi ( 270) 241 46.1 7.6e-05 XP_016857120 (OMIM: 616755) PREDICTED: E3 ubiquiti ( 291) 241 46.2 7.9e-05 NP_067629 (OMIM: 605684) tripartite motif-containi ( 488) 241 46.5 0.00011 NP_001003827 (OMIM: 605684) tripartite motif-conta ( 488) 241 46.5 0.00011 NP_006065 (OMIM: 606559) E3 ubiquitin-protein liga ( 498) 241 46.5 0.00011 XP_016873516 (OMIM: 606124) PREDICTED: tripartite ( 375) 232 45.0 0.00022 NP_963921 (OMIM: 610530) E3 ubiquitin-protein liga ( 518) 233 45.4 0.00025 >>NP_944606 (OMIM: 612549) tripartite motif-containing p (250 aa) initn: 1739 init1: 1739 opt: 1739 Z-score: 1365.1 bits: 260.1 E(85289): 2.7e-69 Smith-Waterman score: 1739; 100.0% identity (100.0% similar) in 250 aa overlap (1-250:1-250) 10 20 30 40 50 60 pF1KE0 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_944 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_944 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_944 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_944 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF 190 200 210 220 230 240 250 pF1KE0 IWKFHSMASR :::::::::: NP_944 IWKFHSMASR 250 >>NP_001304744 (OMIM: 612550) tripartite motif-containin (250 aa) initn: 1729 init1: 1729 opt: 1729 Z-score: 1357.4 bits: 258.7 E(85289): 7.2e-69 Smith-Waterman score: 1729; 99.6% identity (99.6% similar) in 250 aa overlap (1-250:1-250) 10 20 30 40 50 60 pF1KE0 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAWQVSLLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF 190 200 210 220 230 240 250 pF1KE0 IWKFHSMASR :::::::::: NP_001 IWKFHSMASR 250 >>XP_011514489 (OMIM: 612550) PREDICTED: tripartite moti (250 aa) initn: 1729 init1: 1729 opt: 1729 Z-score: 1357.4 bits: 258.7 E(85289): 7.2e-69 Smith-Waterman score: 1729; 99.6% identity (99.6% similar) in 250 aa overlap (1-250:1-250) 10 20 30 40 50 60 pF1KE0 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAWQVSLLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF 190 200 210 220 230 240 250 pF1KE0 IWKFHSMASR :::::::::: XP_011 IWKFHSMASR 250 >>NP_942150 (OMIM: 612550) tripartite motif-containing p (250 aa) initn: 1729 init1: 1729 opt: 1729 Z-score: 1357.4 bits: 258.7 E(85289): 7.2e-69 Smith-Waterman score: 1729; 99.6% identity (99.6% similar) in 250 aa overlap (1-250:1-250) 10 20 30 40 50 60 pF1KE0 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: NP_942 MAWQVSLLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF 190 200 210 220 230 240 250 pF1KE0 IWKFHSMASR :::::::::: NP_942 IWKFHSMASR 250 >>XP_011514491 (OMIM: 612550) PREDICTED: tripartite moti (249 aa) initn: 1709 init1: 1676 opt: 1711 Z-score: 1343.5 bits: 256.1 E(85289): 4.3e-68 Smith-Waterman score: 1711; 99.2% identity (99.2% similar) in 250 aa overlap (1-250:1-249) 10 20 30 40 50 60 pF1KE0 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAWQVSLLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF 190 200 210 220 230 240 250 pF1KE0 IWKFHSMASR :: ::::::: XP_011 IW-FHSMASR >>XP_011514089 (OMIM: 612548) PREDICTED: E3 ubiquitin-pr (304 aa) initn: 1578 init1: 1578 opt: 1578 Z-score: 1239.9 bits: 237.2 E(85289): 2.5e-62 Smith-Waterman score: 1578; 93.2% identity (96.8% similar) in 250 aa overlap (1-250:1-250) 10 20 30 40 50 60 pF1KE0 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV ::::::: ::::::::::::::::: :::::::::::::::::: :::...:::.: :.: XP_011 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGSSSLPNVSLARVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ :::::::: ::::::::::.::::::::::::::::::.::::::::::::::::::::: XP_011 PVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF ::.: :::::::::::::::::::::::::::::::::::::::::::::::::::::.: XP_011 ELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHKF 190 200 210 220 230 240 250 pF1KE0 IWKFHSMASR : :::::::: XP_011 IRKFHSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPGSSPVLAPS 250 260 270 280 290 300 >>NP_001268380 (OMIM: 612548) E3 ubiquitin-protein ligas (487 aa) initn: 1578 init1: 1578 opt: 1578 Z-score: 1237.7 bits: 237.5 E(85289): 3.3e-62 Smith-Waterman score: 1578; 93.2% identity (96.8% similar) in 250 aa overlap (1-250:1-250) 10 20 30 40 50 60 pF1KE0 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV ::::::: ::::::::::::::::: :::::::::::::::::: :::...:::.: :.: NP_001 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGSSSLPNVSLARVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ :::::::: ::::::::::.::::::::::::::::::.::::::::::::::::::::: NP_001 PVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF ::.: :::::::::::::::::::::::::::::::::::::::::::::::::::::.: NP_001 ELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHKF 190 200 210 220 230 240 250 pF1KE0 IWKFHSMASR : :::::::: NP_001 IRKFHSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPEPLKLDP 250 260 270 280 290 300 >>NP_835226 (OMIM: 612548) E3 ubiquitin-protein ligase T (487 aa) initn: 1578 init1: 1578 opt: 1578 Z-score: 1237.7 bits: 237.5 E(85289): 3.3e-62 Smith-Waterman score: 1578; 93.2% identity (96.8% similar) in 250 aa overlap (1-250:1-250) 10 20 30 40 50 60 pF1KE0 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV ::::::: ::::::::::::::::: :::::::::::::::::: :::...:::.: :.: NP_835 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: NP_835 DGSSSLPNVSLARVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ :::::::: ::::::::::.::::::::::::::::::.::::::::::::::::::::: NP_835 PVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF ::.: :::::::::::::::::::::::::::::::::::::::::::::::::::::.: NP_835 ELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHKF 190 200 210 220 230 240 250 pF1KE0 IWKFHSMASR : :::::::: NP_835 IRKFHSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPEPLKLDP 250 260 270 280 290 300 >>XP_011514091 (OMIM: 612548) PREDICTED: E3 ubiquitin-pr (486 aa) initn: 1564 init1: 1528 opt: 1566 Z-score: 1228.5 bits: 235.8 E(85289): 1.1e-61 Smith-Waterman score: 1566; 92.8% identity (96.8% similar) in 250 aa overlap (1-250:1-249) 10 20 30 40 50 60 pF1KE0 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV ::::::: ::::::::::::::::: :::::::::::::::::: :::...:::.: :.: XP_011 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGSSSLPNVSLARVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ :::::::: ::::::::::.::::::::::::::::::.::::::::::::::::::::: XP_011 PVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF ::.: :::::::::::::::::::::::::::::::::::::::::::::::::::::.: XP_011 ELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHKF 190 200 210 220 230 240 250 pF1KE0 IWKFHSMASR : .::::::: XP_011 I-RFHSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPEPLKLDP 250 260 270 280 290 >>NP_001268379 (OMIM: 612548) E3 ubiquitin-protein ligas (486 aa) initn: 1564 init1: 1528 opt: 1566 Z-score: 1228.5 bits: 235.8 E(85289): 1.1e-61 Smith-Waterman score: 1566; 92.8% identity (96.8% similar) in 250 aa overlap (1-250:1-249) 10 20 30 40 50 60 pF1KE0 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV ::::::: ::::::::::::::::: :::::::::::::::::: :::...:::.: :.: NP_001 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGSSSLPNVSLARVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ :::::::: ::::::::::.::::::::::::::::::.::::::::::::::::::::: NP_001 PVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF ::.: :::::::::::::::::::::::::::::::::::::::::::::::::::::.: NP_001 ELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHKF 190 200 210 220 230 240 250 pF1KE0 IWKFHSMASR : .::::::: NP_001 I-RFHSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPEPLKLDP 250 260 270 280 290 250 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:44:16 2016 done: Thu Nov 3 18:44:17 2016 Total Scan time: 6.740 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]