FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0264, 415 aa 1>>>pF1KE0264 415 - 415 aa - 415 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0773+/-0.000363; mu= 18.3119+/- 0.023 mean_var=65.1900+/-13.187, 0's: 0 Z-trim(113.8): 229 B-trim: 821 in 1/51 Lambda= 0.158849 statistics sampled from 23044 (23294) to 23044 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.273), width: 16 Scan time: 8.800 The best scores are: opt bits E(85289) NP_037495 (OMIM: 607064) procollagen C-endopeptida ( 415) 2848 661.6 1e-189 NP_002584 (OMIM: 600270) procollagen C-endopeptida ( 449) 1034 245.9 1.5e-64 XP_011518058 (OMIM: 602069) PREDICTED: neuropilin- ( 628) 514 126.8 1.5e-28 XP_011518057 (OMIM: 602069) PREDICTED: neuropilin- ( 656) 514 126.8 1.6e-28 XP_006717589 (OMIM: 602069) PREDICTED: neuropilin- ( 663) 514 126.8 1.6e-28 XP_006717588 (OMIM: 602069) PREDICTED: neuropilin- ( 888) 514 126.9 2e-28 XP_006717587 (OMIM: 602069) PREDICTED: neuropilin- ( 889) 514 126.9 2e-28 XP_016872354 (OMIM: 602069) PREDICTED: neuropilin- ( 899) 514 126.9 2e-28 XP_006717585 (OMIM: 602069) PREDICTED: neuropilin- ( 907) 514 126.9 2e-28 XP_006717584 (OMIM: 602069) PREDICTED: neuropilin- ( 924) 514 126.9 2.1e-28 NP_963840 (OMIM: 612320) CUB domain-containing pro ( 449) 494 122.1 2.7e-27 XP_011518013 (OMIM: 261100,602997) PREDICTED: cubi (2237) 384 97.4 3.9e-19 XP_011518012 (OMIM: 261100,602997) PREDICTED: cubi (2277) 384 97.4 3.9e-19 XP_011518011 (OMIM: 261100,602997) PREDICTED: cubi (2285) 384 97.4 4e-19 XP_011518010 (OMIM: 261100,602997) PREDICTED: cubi (2867) 384 97.4 4.8e-19 NP_001072 (OMIM: 261100,602997) cubilin precursor (3623) 384 97.5 5.7e-19 XP_006716449 (OMIM: 112264,614856) PREDICTED: bone ( 813) 323 83.1 2.8e-15 XP_016869227 (OMIM: 112264,614856) PREDICTED: bone ( 717) 319 82.1 4.7e-15 NP_001190 (OMIM: 112264,614856) bone morphogenetic ( 730) 318 81.9 5.6e-15 NP_006120 (OMIM: 112264,614856) bone morphogenetic ( 986) 317 81.8 8.4e-15 XP_011530516 (OMIM: 606742,613087) PREDICTED: toll ( 837) 311 80.4 1.9e-14 XP_016864059 (OMIM: 606742,613087) PREDICTED: toll ( 964) 311 80.4 2.1e-14 NP_036596 (OMIM: 606742,613087) tolloid-like prote (1013) 311 80.4 2.2e-14 NP_036597 (OMIM: 606743) tolloid-like protein 2 pr (1015) 307 79.5 4.2e-14 NP_009046 (OMIM: 600410) tumor necrosis factor-ind ( 277) 293 75.9 1.4e-13 NP_113621 (OMIM: 606227,609549,611040) membrane fr ( 579) 291 75.7 3.4e-13 XP_011542919 (OMIM: 112264,614856) PREDICTED: bone ( 622) 285 74.3 9.4e-13 XP_016855682 (OMIM: 608398) PREDICTED: CUB and sus (2294) 283 74.2 3.7e-12 XP_016855681 (OMIM: 608398) PREDICTED: CUB and sus (2315) 283 74.2 3.7e-12 XP_016855680 (OMIM: 608398) PREDICTED: CUB and sus (2973) 283 74.3 4.5e-12 XP_016855679 (OMIM: 608398) PREDICTED: CUB and sus (3362) 283 74.3 5e-12 NP_443128 (OMIM: 608398) CUB and sushi domain-cont (3487) 283 74.3 5.2e-12 XP_016855678 (OMIM: 608398) PREDICTED: CUB and sus (3506) 283 74.3 5.2e-12 XP_016855683 (OMIM: 608398) PREDICTED: CUB and sus (3566) 283 74.3 5.3e-12 XP_016855677 (OMIM: 608398) PREDICTED: CUB and sus (3567) 283 74.3 5.3e-12 XP_016855676 (OMIM: 608398) PREDICTED: CUB and sus (3606) 283 74.3 5.3e-12 XP_016855674 (OMIM: 608398) PREDICTED: CUB and sus (3607) 283 74.3 5.3e-12 XP_016855675 (OMIM: 608398) PREDICTED: CUB and sus (3607) 283 74.3 5.3e-12 NP_001268885 (OMIM: 608398) CUB and sushi domain-c (3631) 283 74.3 5.3e-12 XP_011537717 (OMIM: 601969) PREDICTED: deleted in (1766) 276 72.5 9.1e-12 XP_011537716 (OMIM: 601969) PREDICTED: deleted in (1783) 276 72.5 9.2e-12 NP_004397 (OMIM: 601969) deleted in malignant brai (1785) 276 72.5 9.2e-12 NP_957716 (OMIM: 602070) neuropilin-2 isoform 6 pr ( 555) 270 70.8 9.3e-12 NP_001019800 (OMIM: 602069) neuropilin-1 isoform c ( 609) 270 70.9 1e-11 XP_016871287 (OMIM: 601969) PREDICTED: deleted in (1990) 276 72.6 1e-11 NP_001019799 (OMIM: 602069) neuropilin-1 isoform b ( 644) 270 70.9 1e-11 XP_011537715 (OMIM: 601969) PREDICTED: deleted in (2282) 276 72.6 1.1e-11 NP_060049 (OMIM: 601969) deleted in malignant brai (2403) 276 72.6 1.2e-11 XP_011537713 (OMIM: 601969) PREDICTED: deleted in (2403) 276 72.6 1.2e-11 XP_011537711 (OMIM: 601969) PREDICTED: deleted in (2411) 276 72.6 1.2e-11 >>NP_037495 (OMIM: 607064) procollagen C-endopeptidase e (415 aa) initn: 2848 init1: 2848 opt: 2848 Z-score: 3526.9 bits: 661.6 E(85289): 1e-189 Smith-Waterman score: 2848; 100.0% identity (100.0% similar) in 415 aa overlap (1-415:1-415) 10 20 30 40 50 60 pF1KE0 MRGANAWAPLCLLLAAATQLSRQQSPERPVFTCGGILTGESGFIGSEGFPGVYPPNSKCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 MRGANAWAPLCLLLAAATQLSRQQSPERPVFTCGGILTGESGFIGSEGFPGVYPPNSKCT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WKITVPEGKVVVLNFRFIDLESDNLCRYDFVDVYNGHANGQRIGRFCGTFRPGALVSSGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 WKITVPEGKVVVLNFRFIDLESDNLCRYDFVDVYNGHANGQRIGRFCGTFRPGALVSSGN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 KMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAGVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 KMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAGVT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 CVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYCGDSPPAPIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 CVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYCGDSPPAPIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 SERNELLIQFLSDLSLTADGFIGHYIFRPKKLPTTTEQPVTTTFPVTTGLKPTVALCQQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 SERNELLIQFLSDLSLTADGFIGHYIFRPKKLPTTTEQPVTTTFPVTTGLKPTVALCQQK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 CRRTGTLEGNYCSSDFVLAGTVITTITRDGSLHATVSIINIYKEGNLAIQQAGKNMSARL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 CRRTGTLEGNYCSSDFVLAGTVITTITRDGSLHATVSIINIYKEGNLAIQQAGKNMSARL 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 TVVCKQCPLLRRGLNYIIMGQVGEDGRGKIMPNSFIMMFKTKNQKLLDALKNKQC ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 TVVCKQCPLLRRGLNYIIMGQVGEDGRGKIMPNSFIMMFKTKNQKLLDALKNKQC 370 380 390 400 410 >>NP_002584 (OMIM: 600270) procollagen C-endopeptidase e (449 aa) initn: 1324 init1: 711 opt: 1034 Z-score: 1279.7 bits: 245.9 E(85289): 1.5e-64 Smith-Waterman score: 1328; 44.5% identity (71.6% similar) in 436 aa overlap (4-415:7-437) 10 20 30 40 50 pF1KE0 MRGANAWAPLCLLLAAATQLSRQQSPE--RPVFTCGGILTGESGFIGSEGFPGVYPP :. .:: : : ... :.:. :::: ::: . ::::...:::::..::: NP_002 MLPAATASLLGPL-LTACALLPFAQGQTPNYTRPVFLCGGDVKGESGYVASEGFPNLYPP 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 NSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVDVYNGHA-NGQRIGRFCGTFRPGA :..: : ::::::..: :.:: .::: :::: ..:. : . .:::.:::::::::. NP_002 NKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 LVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRD ::. ::.. ..: .: .:.: ::. .:. . :.::: :.. .:.. :::::. : NP_002 LVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESD 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 YPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYCGDS :: :..: :::.:: .:.: : :::::.: :.::::: :.::::. .:.::.::.:::. NP_002 YPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDA 180 190 200 210 220 230 240 250 260 270 pF1KE0 PPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRPK-------------------KLPTT :. : :: ::::.::.::::.::::: . : :. ::: NP_002 VPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPGPKRGTEPKVKLPPK 240 250 260 270 280 290 280 290 300 310 320 330 pF1KE0 TEQPVTTTFPVTTGLKPTVALCQQKCRRTGTLEGNYCSSDFVLAGTVITTITRDG-SLHA .. : : .. :: : ..:::::::..:.:.:..:...:: . . . : .: . NP_002 SQPPEKTEESPSAPDAPT---CPKQCRRTGTLQSNFCASSLVVTATVKSMVREPGEGLAV 300 310 320 330 340 350 340 350 360 370 380 390 pF1KE0 TVSIINIYKEGNLAIQQAGKNMSARLTVVCKQCPLLRRGLNYIIMGQVGEDGRGKIMP-N :::.:. :: :.: . . . : .. : ::::: ...:..:..:::: :..:: ..: . NP_002 TVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQCPPMKKGVSYLLMGQV-EENRGPVLPPE 360 370 380 390 400 410 400 410 pF1KE0 SFIMMFKTKNQKLLDALKNKQC ::... . .....: :....: NP_002 SFVVLHRPNQDQILTNLSKRKCPSQPVRAAASQD 420 430 440 >>XP_011518058 (OMIM: 602069) PREDICTED: neuropilin-1 is (628 aa) initn: 317 init1: 129 opt: 514 Z-score: 633.5 bits: 126.8 E(85289): 1.5e-28 Smith-Waterman score: 514; 35.4% identity (64.6% similar) in 243 aa overlap (33-265:27-262) 10 20 30 40 50 60 pF1KE0 GANAWAPLCLLLAAATQLSRQQSPERPVFTCGGILTGES-GFIGSEGFPGVYPPNSKCTW :: . :: :.. : :.: : :. :: : XP_011 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEW 10 20 30 40 50 70 80 90 100 110 pF1KE0 KITVPEG-KVVVLNFR-FIDLESDNLCRYDFVDVYNG-HANGQRIGRFCGTFRPGALVSS : .:. . ...:: .::: : :.::.:.:..: . ::. :.::: . : .::: XP_011 LIQAPDPYQRIMINFNPHFDLE-DRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 GNKMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAG : ......:: .: : :: . : .:: . :. ::: .:.:..:.. :: . XP_011 GPFLFIKFVSDYETHGAGFSIRY---EIFKRGPE-CSQNYTTPSGVIKSPGFPEK-YPNS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 VTCVWHIVAPKNQLIELKFEKFDVERDN------YCRYDYVAVFNGGEVNDARRIGKYCG . :.. . .:: . : :.::.::.: :. .:::: . ...: . . .::.::: XP_011 LECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFP-DVGPHIGRYCG 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 DSPPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRPKKLPTTTEQPVTTTFPVTTGLKP .. :. : : . : . : .: ... .:: ..: XP_011 QKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSD 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE0 TVALCQQKCRRTGTLEGNYCSSDFVLAGTVITTITRDGSLHATVSIINIYKEGNLAIQQA XP_011 QITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKET 290 300 310 320 330 340 >>XP_011518057 (OMIM: 602069) PREDICTED: neuropilin-1 is (656 aa) initn: 317 init1: 129 opt: 514 Z-score: 633.3 bits: 126.8 E(85289): 1.6e-28 Smith-Waterman score: 514; 35.4% identity (64.6% similar) in 243 aa overlap (33-265:27-262) 10 20 30 40 50 60 pF1KE0 GANAWAPLCLLLAAATQLSRQQSPERPVFTCGGILTGES-GFIGSEGFPGVYPPNSKCTW :: . :: :.. : :.: : :. :: : XP_011 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEW 10 20 30 40 50 70 80 90 100 110 pF1KE0 KITVPEG-KVVVLNFR-FIDLESDNLCRYDFVDVYNG-HANGQRIGRFCGTFRPGALVSS : .:. . ...:: .::: : :.::.:.:..: . ::. :.::: . : .::: XP_011 LIQAPDPYQRIMINFNPHFDLE-DRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 GNKMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAG : ......:: .: : :: . : .:: . :. ::: .:.:..:.. :: . XP_011 GPFLFIKFVSDYETHGAGFSIRY---EIFKRGPE-CSQNYTTPSGVIKSPGFPEK-YPNS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 VTCVWHIVAPKNQLIELKFEKFDVERDN------YCRYDYVAVFNGGEVNDARRIGKYCG . :.. . .:: . : :.::.::.: :. .:::: . ...: . . .::.::: XP_011 LECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFP-DVGPHIGRYCG 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 DSPPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRPKKLPTTTEQPVTTTFPVTTGLKP .. :. : : . : . : .: ... .:: ..: XP_011 QKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSD 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE0 TVALCQQKCRRTGTLEGNYCSSDFVLAGTVITTITRDGSLHATVSIINIYKEGNLAIQQA XP_011 QITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKET 290 300 310 320 330 340 >>XP_006717589 (OMIM: 602069) PREDICTED: neuropilin-1 is (663 aa) initn: 317 init1: 129 opt: 514 Z-score: 633.2 bits: 126.8 E(85289): 1.6e-28 Smith-Waterman score: 514; 35.4% identity (64.6% similar) in 243 aa overlap (33-265:27-262) 10 20 30 40 50 60 pF1KE0 GANAWAPLCLLLAAATQLSRQQSPERPVFTCGGILTGES-GFIGSEGFPGVYPPNSKCTW :: . :: :.. : :.: : :. :: : XP_006 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEW 10 20 30 40 50 70 80 90 100 110 pF1KE0 KITVPEG-KVVVLNFR-FIDLESDNLCRYDFVDVYNG-HANGQRIGRFCGTFRPGALVSS : .:. . ...:: .::: : :.::.:.:..: . ::. :.::: . : .::: XP_006 LIQAPDPYQRIMINFNPHFDLE-DRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 GNKMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAG : ......:: .: : :: . : .:: . :. ::: .:.:..:.. :: . XP_006 GPFLFIKFVSDYETHGAGFSIRY---EIFKRGPE-CSQNYTTPSGVIKSPGFPEK-YPNS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 VTCVWHIVAPKNQLIELKFEKFDVERDN------YCRYDYVAVFNGGEVNDARRIGKYCG . :.. . .:: . : :.::.::.: :. .:::: . ...: . . .::.::: XP_006 LECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFP-DVGPHIGRYCG 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 DSPPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRPKKLPTTTEQPVTTTFPVTTGLKP .. :. : : . : . : .: ... .:: ..: XP_006 QKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSD 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE0 TVALCQQKCRRTGTLEGNYCSSDFVLAGTVITTITRDGSLHATVSIINIYKEGNLAIQQA XP_006 QITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKET 290 300 310 320 330 340 >>XP_006717588 (OMIM: 602069) PREDICTED: neuropilin-1 is (888 aa) initn: 317 init1: 129 opt: 514 Z-score: 631.4 bits: 126.9 E(85289): 2e-28 Smith-Waterman score: 514; 35.4% identity (64.6% similar) in 243 aa overlap (33-265:27-262) 10 20 30 40 50 60 pF1KE0 GANAWAPLCLLLAAATQLSRQQSPERPVFTCGGILTGES-GFIGSEGFPGVYPPNSKCTW :: . :: :.. : :.: : :. :: : XP_006 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEW 10 20 30 40 50 70 80 90 100 110 pF1KE0 KITVPEG-KVVVLNFR-FIDLESDNLCRYDFVDVYNG-HANGQRIGRFCGTFRPGALVSS : .:. . ...:: .::: : :.::.:.:..: . ::. :.::: . : .::: XP_006 LIQAPDPYQRIMINFNPHFDLE-DRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 GNKMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAG : ......:: .: : :: . : .:: . :. ::: .:.:..:.. :: . XP_006 GPFLFIKFVSDYETHGAGFSIRY---EIFKRGPE-CSQNYTTPSGVIKSPGFPEK-YPNS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 VTCVWHIVAPKNQLIELKFEKFDVERDN------YCRYDYVAVFNGGEVNDARRIGKYCG . :.. . .:: . : :.::.::.: :. .:::: . ...: . . .::.::: XP_006 LECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFP-DVGPHIGRYCG 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 DSPPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRPKKLPTTTEQPVTTTFPVTTGLKP .. :. : : . : . : .: ... .:: ..: XP_006 QKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSD 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE0 TVALCQQKCRRTGTLEGNYCSSDFVLAGTVITTITRDGSLHATVSIINIYKEGNLAIQQA XP_006 QITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKET 290 300 310 320 330 340 >>XP_006717587 (OMIM: 602069) PREDICTED: neuropilin-1 is (889 aa) initn: 317 init1: 129 opt: 514 Z-score: 631.3 bits: 126.9 E(85289): 2e-28 Smith-Waterman score: 514; 35.4% identity (64.6% similar) in 243 aa overlap (33-265:27-262) 10 20 30 40 50 60 pF1KE0 GANAWAPLCLLLAAATQLSRQQSPERPVFTCGGILTGES-GFIGSEGFPGVYPPNSKCTW :: . :: :.. : :.: : :. :: : XP_006 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEW 10 20 30 40 50 70 80 90 100 110 pF1KE0 KITVPEG-KVVVLNFR-FIDLESDNLCRYDFVDVYNG-HANGQRIGRFCGTFRPGALVSS : .:. . ...:: .::: : :.::.:.:..: . ::. :.::: . : .::: XP_006 LIQAPDPYQRIMINFNPHFDLE-DRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 GNKMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAG : ......:: .: : :: . : .:: . :. ::: .:.:..:.. :: . XP_006 GPFLFIKFVSDYETHGAGFSIRY---EIFKRGPE-CSQNYTTPSGVIKSPGFPEK-YPNS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 VTCVWHIVAPKNQLIELKFEKFDVERDN------YCRYDYVAVFNGGEVNDARRIGKYCG . :.. . .:: . : :.::.::.: :. .:::: . ...: . . .::.::: XP_006 LECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFP-DVGPHIGRYCG 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 DSPPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRPKKLPTTTEQPVTTTFPVTTGLKP .. :. : : . : . : .: ... .:: ..: XP_006 QKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSD 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE0 TVALCQQKCRRTGTLEGNYCSSDFVLAGTVITTITRDGSLHATVSIINIYKEGNLAIQQA XP_006 QITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKET 290 300 310 320 330 340 >>XP_016872354 (OMIM: 602069) PREDICTED: neuropilin-1 is (899 aa) initn: 317 init1: 129 opt: 514 Z-score: 631.3 bits: 126.9 E(85289): 2e-28 Smith-Waterman score: 514; 35.4% identity (64.6% similar) in 243 aa overlap (33-265:27-262) 10 20 30 40 50 60 pF1KE0 GANAWAPLCLLLAAATQLSRQQSPERPVFTCGGILTGES-GFIGSEGFPGVYPPNSKCTW :: . :: :.. : :.: : :. :: : XP_016 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEW 10 20 30 40 50 70 80 90 100 110 pF1KE0 KITVPEG-KVVVLNFR-FIDLESDNLCRYDFVDVYNG-HANGQRIGRFCGTFRPGALVSS : .:. . ...:: .::: : :.::.:.:..: . ::. :.::: . : .::: XP_016 LIQAPDPYQRIMINFNPHFDLE-DRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 GNKMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAG : ......:: .: : :: . : .:: . :. ::: .:.:..:.. :: . XP_016 GPFLFIKFVSDYETHGAGFSIRY---EIFKRGPE-CSQNYTTPSGVIKSPGFPEK-YPNS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 VTCVWHIVAPKNQLIELKFEKFDVERDN------YCRYDYVAVFNGGEVNDARRIGKYCG . :.. . .:: . : :.::.::.: :. .:::: . ...: . . .::.::: XP_016 LECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFP-DVGPHIGRYCG 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 DSPPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRPKKLPTTTEQPVTTTFPVTTGLKP .. :. : : . : . : .: ... .:: ..: XP_016 QKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSD 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE0 TVALCQQKCRRTGTLEGNYCSSDFVLAGTVITTITRDGSLHATVSIINIYKEGNLAIQQA XP_016 QITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKET 290 300 310 320 330 340 >>XP_006717585 (OMIM: 602069) PREDICTED: neuropilin-1 is (907 aa) initn: 317 init1: 129 opt: 514 Z-score: 631.2 bits: 126.9 E(85289): 2e-28 Smith-Waterman score: 514; 35.4% identity (64.6% similar) in 243 aa overlap (33-265:27-262) 10 20 30 40 50 60 pF1KE0 GANAWAPLCLLLAAATQLSRQQSPERPVFTCGGILTGES-GFIGSEGFPGVYPPNSKCTW :: . :: :.. : :.: : :. :: : XP_006 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEW 10 20 30 40 50 70 80 90 100 110 pF1KE0 KITVPEG-KVVVLNFR-FIDLESDNLCRYDFVDVYNG-HANGQRIGRFCGTFRPGALVSS : .:. . ...:: .::: : :.::.:.:..: . ::. :.::: . : .::: XP_006 LIQAPDPYQRIMINFNPHFDLE-DRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 GNKMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAG : ......:: .: : :: . : .:: . :. ::: .:.:..:.. :: . XP_006 GPFLFIKFVSDYETHGAGFSIRY---EIFKRGPE-CSQNYTTPSGVIKSPGFPEK-YPNS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 VTCVWHIVAPKNQLIELKFEKFDVERDN------YCRYDYVAVFNGGEVNDARRIGKYCG . :.. . .:: . : :.::.::.: :. .:::: . ...: . . .::.::: XP_006 LECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFP-DVGPHIGRYCG 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 DSPPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRPKKLPTTTEQPVTTTFPVTTGLKP .. :. : : . : . : .: ... .:: ..: XP_006 QKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSD 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE0 TVALCQQKCRRTGTLEGNYCSSDFVLAGTVITTITRDGSLHATVSIINIYKEGNLAIQQA XP_006 QITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKET 290 300 310 320 330 340 >>XP_006717584 (OMIM: 602069) PREDICTED: neuropilin-1 is (924 aa) initn: 317 init1: 129 opt: 514 Z-score: 631.1 bits: 126.9 E(85289): 2.1e-28 Smith-Waterman score: 514; 35.4% identity (64.6% similar) in 243 aa overlap (33-265:27-262) 10 20 30 40 50 60 pF1KE0 GANAWAPLCLLLAAATQLSRQQSPERPVFTCGGILTGES-GFIGSEGFPGVYPPNSKCTW :: . :: :.. : :.: : :. :: : XP_006 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEW 10 20 30 40 50 70 80 90 100 110 pF1KE0 KITVPEG-KVVVLNFR-FIDLESDNLCRYDFVDVYNG-HANGQRIGRFCGTFRPGALVSS : .:. . ...:: .::: : :.::.:.:..: . ::. :.::: . : .::: XP_006 LIQAPDPYQRIMINFNPHFDLE-DRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 GNKMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAG : ......:: .: : :: . : .:: . :. ::: .:.:..:.. :: . XP_006 GPFLFIKFVSDYETHGAGFSIRY---EIFKRGPE-CSQNYTTPSGVIKSPGFPEK-YPNS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 VTCVWHIVAPKNQLIELKFEKFDVERDN------YCRYDYVAVFNGGEVNDARRIGKYCG . :.. . .:: . : :.::.::.: :. .:::: . ...: . . .::.::: XP_006 LECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFP-DVGPHIGRYCG 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 DSPPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRPKKLPTTTEQPVTTTFPVTTGLKP .. :. : : . : . : .: ... .:: ..: XP_006 QKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSD 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE0 TVALCQQKCRRTGTLEGNYCSSDFVLAGTVITTITRDGSLHATVSIINIYKEGNLAIQQA XP_006 QITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKET 290 300 310 320 330 340 415 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:28:59 2016 done: Thu Nov 3 18:29:01 2016 Total Scan time: 8.800 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]