FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0265, 130 aa 1>>>pF1KE0265 130 - 130 aa - 130 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9756+/-0.000328; mu= 12.5317+/- 0.020 mean_var=57.7312+/-11.606, 0's: 0 Z-trim(115.5): 45 B-trim: 575 in 2/51 Lambda= 0.168799 statistics sampled from 25999 (26054) to 25999 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.305), width: 16 Scan time: 5.010 The best scores are: opt bits E(85289) NP_003507 (OMIM: 142720) histone H2A type 2-A [Hom ( 130) 826 208.8 2e-54 NP_003505 (OMIM: 602796) histone H2A type 1 [Homo ( 130) 819 207.1 6.6e-54 NP_003503 (OMIM: 602794) histone H2A type 1-C [Hom ( 130) 819 207.1 6.6e-54 NP_003500 (OMIM: 602787) histone H2A type 1 [Homo ( 130) 819 207.1 6.6e-54 NP_003502 (OMIM: 602793) histone H2A type 1 [Homo ( 130) 819 207.1 6.6e-54 NP_066408 (OMIM: 615012) histone H2A type 1 [Homo ( 130) 819 207.1 6.6e-54 NP_003501 (OMIM: 602788) histone H2A type 1 [Homo ( 130) 819 207.1 6.6e-54 NP_254280 (OMIM: 615015) histone H2A type 3 [Homo ( 130) 815 206.1 1.3e-53 NP_066409 (OMIM: 602792) histone H2A type 1-D [Hom ( 130) 815 206.1 1.3e-53 NP_003504 (OMIM: 602795) histone H2A type 1-B/E [H ( 130) 812 205.4 2.2e-53 NP_066390 (OMIM: 602786) histone H2A type 1-B/E [H ( 130) 812 205.4 2.2e-53 NP_542163 (OMIM: 615013) histone H2A type 1-H [Hom ( 128) 805 203.7 6.9e-53 NP_066544 (OMIM: 602791) histone cluster 1, H2aj [ ( 128) 800 202.5 1.6e-52 NP_003508 (OMIM: 602797) histone H2A type 2-C [Hom ( 129) 796 201.5 3.2e-52 NP_778235 (OMIM: 615014) histone H2A type 2-B [Hom ( 130) 783 198.3 2.9e-51 NP_734466 (OMIM: 613499) histone H2A type 1-A [Hom ( 131) 780 197.6 4.8e-51 NP_002096 (OMIM: 601772) histone H2AX [Homo sapien ( 143) 738 187.4 6.2e-48 XP_011542037 (OMIM: 610054) PREDICTED: core histon ( 195) 500 129.5 2.3e-30 XP_011542036 (OMIM: 610054) PREDICTED: core histon ( 196) 500 129.5 2.3e-30 XP_005272192 (OMIM: 610054) PREDICTED: core histon ( 198) 500 129.5 2.3e-30 XP_005272191 (OMIM: 610054) PREDICTED: core histon ( 199) 500 129.5 2.3e-30 XP_016865558 (OMIM: 610054) PREDICTED: core histon ( 222) 500 129.5 2.5e-30 XP_016865557 (OMIM: 610054) PREDICTED: core histon ( 235) 500 129.5 2.6e-30 XP_016865556 (OMIM: 610054) PREDICTED: core histon ( 251) 500 129.6 2.8e-30 XP_011542035 (OMIM: 610054) PREDICTED: core histon ( 252) 500 129.6 2.8e-30 XP_011542034 (OMIM: 610054) PREDICTED: core histon ( 269) 500 129.6 3e-30 XP_011542033 (OMIM: 610054) PREDICTED: core histon ( 270) 500 129.6 3e-30 XP_005272189 (OMIM: 610054) PREDICTED: core histon ( 368) 500 129.6 3.8e-30 NP_613075 (OMIM: 610054) core histone macro-H2A.1 ( 369) 500 129.6 3.9e-30 NP_004884 (OMIM: 610054) core histone macro-H2A.1 ( 371) 500 129.6 3.9e-30 NP_001035248 (OMIM: 610054) core histone macro-H2A ( 371) 500 129.6 3.9e-30 XP_011542032 (OMIM: 610054) PREDICTED: core histon ( 371) 500 129.6 3.9e-30 XP_011542031 (OMIM: 610054) PREDICTED: core histon ( 372) 500 129.6 3.9e-30 NP_613258 (OMIM: 610054) core histone macro-H2A.1 ( 372) 500 129.6 3.9e-30 NP_061119 (OMIM: 616141) core histone macro-H2A.2 ( 372) 490 127.2 2.1e-29 NP_002097 (OMIM: 142763) histone H2A.Z [Homo sapie ( 128) 455 118.4 3.2e-27 NP_542451 (OMIM: 300445) histone H2A-Bbd type 2/3 ( 115) 300 80.7 6.6e-16 XP_011531366 (OMIM: 135300,182530,610733) PREDICTE (1276) 158 46.6 0.00013 XP_005264572 (OMIM: 135300,182530,610733) PREDICTE (1318) 158 46.7 0.00013 XP_011531364 (OMIM: 135300,182530,610733) PREDICTE (1326) 158 46.7 0.00013 NP_005624 (OMIM: 135300,182530,610733) son of seve (1333) 158 46.7 0.00013 NP_008870 (OMIM: 601247,616559) son of sevenless h (1332) 137 41.5 0.0046 >>NP_003507 (OMIM: 142720) histone H2A type 2-A [Homo sa (130 aa) initn: 826 init1: 826 opt: 826 Z-score: 1098.0 bits: 208.8 E(85289): 2e-54 Smith-Waterman score: 826; 100.0% identity (100.0% similar) in 130 aa overlap (1-130:1-130) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 130 pF1KE0 TESHHKAKGK :::::::::: NP_003 TESHHKAKGK 130 >>NP_003505 (OMIM: 602796) histone H2A type 1 [Homo sapi (130 aa) initn: 819 init1: 819 opt: 819 Z-score: 1088.8 bits: 207.1 E(85289): 6.6e-54 Smith-Waterman score: 819; 98.5% identity (100.0% similar) in 130 aa overlap (1-130:1-130) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLT ::::::::::::::::.::::::::::::::::::::::::::::::::::.:::::::: NP_003 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 130 pF1KE0 TESHHKAKGK :::::::::: NP_003 TESHHKAKGK 130 >>NP_003503 (OMIM: 602794) histone H2A type 1-C [Homo sa (130 aa) initn: 819 init1: 819 opt: 819 Z-score: 1088.8 bits: 207.1 E(85289): 6.6e-54 Smith-Waterman score: 819; 98.5% identity (100.0% similar) in 130 aa overlap (1-130:1-130) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLT :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: NP_003 MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: NP_003 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 130 pF1KE0 TESHHKAKGK :::::::::: NP_003 TESHHKAKGK 130 >>NP_003500 (OMIM: 602787) histone H2A type 1 [Homo sapi (130 aa) initn: 819 init1: 819 opt: 819 Z-score: 1088.8 bits: 207.1 E(85289): 6.6e-54 Smith-Waterman score: 819; 98.5% identity (100.0% similar) in 130 aa overlap (1-130:1-130) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLT ::::::::::::::::.::::::::::::::::::::::::::::::::::.:::::::: NP_003 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 130 pF1KE0 TESHHKAKGK :::::::::: NP_003 TESHHKAKGK 130 >>NP_003502 (OMIM: 602793) histone H2A type 1 [Homo sapi (130 aa) initn: 819 init1: 819 opt: 819 Z-score: 1088.8 bits: 207.1 E(85289): 6.6e-54 Smith-Waterman score: 819; 98.5% identity (100.0% similar) in 130 aa overlap (1-130:1-130) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLT ::::::::::::::::.::::::::::::::::::::::::::::::::::.:::::::: NP_003 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 130 pF1KE0 TESHHKAKGK :::::::::: NP_003 TESHHKAKGK 130 >>NP_066408 (OMIM: 615012) histone H2A type 1 [Homo sapi (130 aa) initn: 819 init1: 819 opt: 819 Z-score: 1088.8 bits: 207.1 E(85289): 6.6e-54 Smith-Waterman score: 819; 98.5% identity (100.0% similar) in 130 aa overlap (1-130:1-130) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLT ::::::::::::::::.::::::::::::::::::::::::::::::::::.:::::::: NP_066 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 130 pF1KE0 TESHHKAKGK :::::::::: NP_066 TESHHKAKGK 130 >>NP_003501 (OMIM: 602788) histone H2A type 1 [Homo sapi (130 aa) initn: 819 init1: 819 opt: 819 Z-score: 1088.8 bits: 207.1 E(85289): 6.6e-54 Smith-Waterman score: 819; 98.5% identity (100.0% similar) in 130 aa overlap (1-130:1-130) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLT ::::::::::::::::.::::::::::::::::::::::::::::::::::.:::::::: NP_003 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 130 pF1KE0 TESHHKAKGK :::::::::: NP_003 TESHHKAKGK 130 >>NP_254280 (OMIM: 615015) histone H2A type 3 [Homo sapi (130 aa) initn: 815 init1: 815 opt: 815 Z-score: 1083.5 bits: 206.1 E(85289): 1.3e-53 Smith-Waterman score: 815; 97.7% identity (100.0% similar) in 130 aa overlap (1-130:1-130) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLT ::::::::::::::::::::::::::::::::::::::::.::::::::::.:::::::: NP_254 MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: NP_254 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 130 pF1KE0 TESHHKAKGK :::::::::: NP_254 TESHHKAKGK 130 >>NP_066409 (OMIM: 602792) histone H2A type 1-D [Homo sa (130 aa) initn: 815 init1: 815 opt: 815 Z-score: 1083.5 bits: 206.1 E(85289): 1.3e-53 Smith-Waterman score: 815; 97.7% identity (100.0% similar) in 130 aa overlap (1-130:1-130) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLT ::::::::::::::::.:::::::::::::::::::::::.::::::::::.:::::::: NP_066 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 130 pF1KE0 TESHHKAKGK :::::::::: NP_066 TESHHKAKGK 130 >>NP_003504 (OMIM: 602795) histone H2A type 1-B/E [Homo (130 aa) initn: 812 init1: 812 opt: 812 Z-score: 1079.6 bits: 205.4 E(85289): 2.2e-53 Smith-Waterman score: 812; 96.9% identity (100.0% similar) in 130 aa overlap (1-130:1-130) 10 20 30 40 50 60 pF1KE0 MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLT ::::::::::::::::.:::::::::::::::::::::::.::::::::::.:::::::: NP_003 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: NP_003 AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKK 70 80 90 100 110 120 130 pF1KE0 TESHHKAKGK :::::::::: NP_003 TESHHKAKGK 130 130 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:21:07 2016 done: Thu Nov 3 18:21:08 2016 Total Scan time: 5.010 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]