Result of FASTA (ccds) for
pF1KE0267
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0267, 315 aa
1>>>pF1KE0267 315 - 315 aa - 315 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9713+/-0.000799; mu= 13.4132+/- 0.048
mean_var=91.6416+/-18.188, 0's: 0 Z-trim(109.9): 62 B-trim: 0 in 0/52
Lambda= 0.133976
statistics sampled from 11123 (11185) to 11123 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.704), E-opt: 0.2 (0.344), width: 16
Scan time: 2.380
The best scores are: opt bits E(32554)
CCDS45931.1 HSD11B1L gene_id:374875|Hs108|chr19 ( 315) 2082 412.2 2.7e-115
CCDS12145.1 HSD11B1L gene_id:374875|Hs108|chr19 ( 286) 1439 287.9 6.5e-78
CCDS74266.1 HSD11B1L gene_id:374875|Hs108|chr19 ( 333) 1439 287.9 7.4e-78
CCDS58641.1 HSD11B1L gene_id:374875|Hs108|chr19 ( 234) 1400 280.3 1e-75
CCDS45932.1 HSD11B1L gene_id:374875|Hs108|chr19 ( 181) 1199 241.3 4.2e-64
CCDS12146.1 HSD11B1L gene_id:374875|Hs108|chr19 ( 199) 870 177.8 6.3e-45
CCDS12144.1 HSD11B1L gene_id:374875|Hs108|chr19 ( 205) 757 155.9 2.4e-38
CCDS1489.1 HSD11B1 gene_id:3290|Hs108|chr1 ( 292) 640 133.4 2.1e-31
CCDS58642.1 HSD11B1L gene_id:374875|Hs108|chr19 ( 152) 556 117.0 9.4e-27
CCDS9743.1 DHRS7 gene_id:51635|Hs108|chr14 ( 339) 306 68.9 6.3e-12
CCDS81810.1 DHRS7 gene_id:51635|Hs108|chr14 ( 289) 301 67.9 1.1e-11
>>CCDS45931.1 HSD11B1L gene_id:374875|Hs108|chr19 (315 aa)
initn: 2082 init1: 2082 opt: 2082 Z-score: 2183.3 bits: 412.2 E(32554): 2.7e-115
Smith-Waterman score: 2082; 100.0% identity (100.0% similar) in 315 aa overlap (1-315:1-315)
10 20 30 40 50 60
pF1KE0 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVR
250 260 270 280 290 300
310
pF1KE0 RLCRGLARPHLFGHD
:::::::::::::::
CCDS45 RLCRGLARPHLFGHD
310
>>CCDS12145.1 HSD11B1L gene_id:374875|Hs108|chr19 (286 aa)
initn: 1437 init1: 1437 opt: 1439 Z-score: 1512.2 bits: 287.9 E(32554): 6.5e-78
Smith-Waterman score: 1439; 97.0% identity (97.4% similar) in 232 aa overlap (1-232:1-232)
10 20 30 40 50 60
pF1KE0 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 AGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQ
:::::::::::::::::::::::::::::::::::::::::::. : :
CCDS12 AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVR
CCDS12 IRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA
250 260 270 280
>>CCDS74266.1 HSD11B1L gene_id:374875|Hs108|chr19 (333 aa)
initn: 1437 init1: 1437 opt: 1439 Z-score: 1511.3 bits: 287.9 E(32554): 7.4e-78
Smith-Waterman score: 1439; 97.0% identity (97.4% similar) in 232 aa overlap (1-232:48-279)
10 20 30
pF1KE0 MKVLLLTGLGALFFAYYWDDNFDPASLQGA
::::::::::::::::::::::::::::::
CCDS74 SCLSLPNIWITGMPVPATSVPCPSAGPHRTMKVLLLTGLGALFFAYYWDDNFDPASLQGA
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE0 RVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 RVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMAS
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE0 PEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRAL
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE0 PSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVL
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE0 GLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGARTLTETPLRGWPQPKM
:::::::::::::. : :
CCDS74 GLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRP
260 270 280 290 300 310
>>CCDS58641.1 HSD11B1L gene_id:374875|Hs108|chr19 (234 aa)
initn: 1400 init1: 1400 opt: 1400 Z-score: 1472.7 bits: 280.3 E(32554): 1e-75
Smith-Waterman score: 1400; 100.0% identity (100.0% similar) in 210 aa overlap (106-315:25-234)
80 90 100 110 120 130
pF1KE0 LGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLM
::::::::::::::::::::::::::::::
CCDS58 MKVLLLTGLGALFFAYYWDDNFDPGGLDYLVLNHIGGAPAGTRARSPQATRWLM
10 20 30 40 50
140 150 160 170 180 190
pF1KE0 QVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 QVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRE
60 70 80 90 100 110
200 210 220 230 240 250
pF1KE0 LDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 LDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGAR
120 130 140 150 160 170
260 270 280 290 300 310
pF1KE0 TLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 TLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGHD
180 190 200 210 220 230
>>CCDS45932.1 HSD11B1L gene_id:374875|Hs108|chr19 (181 aa)
initn: 1199 init1: 1199 opt: 1199 Z-score: 1264.4 bits: 241.3 E(32554): 4.2e-64
Smith-Waterman score: 1199; 100.0% identity (100.0% similar) in 181 aa overlap (135-315:1-181)
110 120 130 140 150 160
pF1KE0 LGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVS
::::::::::::::::::::::::::::::
CCDS45 MQVNFVSYVQLTSRALPSLTDSKGSLVVVS
10 20 30
170 180 190 200 210 220
pF1KE0 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRS
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE0 STSRPRQPEHRGVPLQSQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 STSRPRQPEHRGVPLQSQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDG
100 110 120 130 140 150
290 300 310
pF1KE0 HLEPVTAWEVQVPRVRRLCRGLARPHLFGHD
:::::::::::::::::::::::::::::::
CCDS45 HLEPVTAWEVQVPRVRRLCRGLARPHLFGHD
160 170 180
>>CCDS12146.1 HSD11B1L gene_id:374875|Hs108|chr19 (199 aa)
initn: 895 init1: 868 opt: 870 Z-score: 920.1 bits: 177.8 E(32554): 6.3e-45
Smith-Waterman score: 870; 95.2% identity (95.9% similar) in 145 aa overlap (88-232:1-145)
60 70 80 90 100 110
pF1KE0 LTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIG
::::::::::::::::::::::::::::::
CCDS12 MASPEAPESVVQFALDKLGGLDYLVLNHIG
10 20 30
120 130 140 150 160 170
pF1KE0 GAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 GAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTP
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE0 YSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGV
::::::::::::::::::::::::::::::::::::::::::::::. : :
CCDS12 YSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAA
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE0 PLQSQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVP
CCDS12 LAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA
160 170 180 190
>>CCDS12144.1 HSD11B1L gene_id:374875|Hs108|chr19 (205 aa)
initn: 943 init1: 755 opt: 757 Z-score: 801.9 bits: 155.9 E(32554): 2.4e-38
Smith-Waterman score: 757; 94.5% identity (95.3% similar) in 127 aa overlap (106-232:25-151)
80 90 100 110 120 130
pF1KE0 LGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLM
::::::::::::::::::::::::::::::
CCDS12 MKVLLLTGLGALFFAYYWDDNFDPGGLDYLVLNHIGGAPAGTRARSPQATRWLM
10 20 30 40 50
140 150 160 170 180 190
pF1KE0 QVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 QVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRE
60 70 80 90 100 110
200 210 220 230 240 250
pF1KE0 LDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGAR
::::::::::::::::::::::::::::. : :
CCDS12 LDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYPW
120 130 140 150 160 170
260 270 280 290 300 310
pF1KE0 TLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGHD
CCDS12 RFRLLCLLRRWLPRPRAWFIRQELNVTAAAA
180 190 200
>>CCDS1489.1 HSD11B1 gene_id:3290|Hs108|chr1 (292 aa)
initn: 623 init1: 623 opt: 640 Z-score: 677.5 bits: 133.4 E(32554): 2.1e-31
Smith-Waterman score: 640; 49.3% identity (73.8% similar) in 225 aa overlap (1-222:4-227)
10 20 30 40 50
pF1KE0 MKVLLLTGLGALFFAYYW---DDNFDPASLQGARVLLTGANAGVGEELAYHYARLGS
:: :: :: ::.:::. ...: : ::: .:..:::. :.:.:.::: :..:.
CCDS14 MAFMKKYLLPILG-LFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGA
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 HLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLN
:.:.::... :::::..: .::: .. :::. : . :. : : .::::.:.::
CCDS14 HVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 HIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSF
:: .. . . . .: :.:::.::: :: ::: : .:.::.:::::: :.: .
CCDS14 HITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPM
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 STPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEH
. :::.::::::::.:.:.: .:. :::.::.::::: : .: .::
CCDS14 VAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 RGVPLQSQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEV
CCDS14 ECALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINK
240 250 260 270 280 290
>>CCDS58642.1 HSD11B1L gene_id:374875|Hs108|chr19 (152 aa)
initn: 581 init1: 554 opt: 556 Z-score: 593.8 bits: 117.0 E(32554): 9.4e-27
Smith-Waterman score: 556; 92.9% identity (93.9% similar) in 98 aa overlap (135-232:1-98)
110 120 130 140 150 160
pF1KE0 LGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVS
::::::::::::::::::::::::::::::
CCDS58 MQVNFVSYVQLTSRALPSLTDSKGSLVVVS
10 20 30
170 180 190 200 210 220
pF1KE0 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
CCDS58 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRG
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE0 STSRPRQPEHRGVPLQSQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDG
: :
CCDS58 VTRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAA
100 110 120 130 140 150
>>CCDS9743.1 DHRS7 gene_id:51635|Hs108|chr14 (339 aa)
initn: 208 init1: 116 opt: 306 Z-score: 327.6 bits: 68.9 E(32554): 6.3e-12
Smith-Waterman score: 306; 31.8% identity (61.7% similar) in 214 aa overlap (1-208:23-233)
10 20 30
pF1KE0 MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGAN
.. : : .:..: :. : : .:::.
CCDS97 MNWELLLWLLVLCALLLLLVQLLRFLRADGDLTLLWAE-WQGRRPEWELTDMVVWVTGAS
10 20 30 40 50
40 50 60 70 80 90
pF1KE0 AGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPK---VFYIAADMASPEAPE
.:.::::::. ..:: :::.:. :..: : . : : .. . :... . :
CCDS97 SGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHE
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE0 SVVQFALDKLGGLDYLVLNHIGGAPAGTRA--RSPQATRWLMQVNFVSYVQLTSRALPSL
.... .:...: .: :: : :: . : .. : :...:... :.::. .:: .
CCDS97 AATKAVLQEFGRIDILVNN--GGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHM
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE0 TDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGL
. : :..:.:.:.:: . . .: : :.: :: :::..:: :: . .. ..:
CCDS97 IERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPV
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE0 RDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGARTLTETPLRGWPQPKMKS
CCDS97 QSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYL
240 250 260 270 280 290
315 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 18:18:14 2016 done: Thu Nov 3 18:18:14 2016
Total Scan time: 2.380 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]