FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0268, 220 aa 1>>>pF1KE0268 220 - 220 aa - 220 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1112+/-0.000716; mu= 13.2333+/- 0.044 mean_var=133.5771+/-25.758, 0's: 0 Z-trim(114.9): 75 B-trim: 0 in 0/53 Lambda= 0.110971 statistics sampled from 15336 (15416) to 15336 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.806), E-opt: 0.2 (0.474), width: 16 Scan time: 2.480 The best scores are: opt bits E(32554) CCDS8170.1 CABP2 gene_id:51475|Hs108|chr11 ( 220) 1500 250.2 7.5e-67 CCDS9205.1 CABP1 gene_id:9478|Hs108|chr12 ( 227) 893 153.1 1.4e-37 CCDS31913.1 CABP1 gene_id:9478|Hs108|chr12 ( 370) 827 142.7 2.9e-34 CCDS9204.1 CABP1 gene_id:9478|Hs108|chr12 ( 167) 794 137.1 6.6e-33 CCDS12709.1 CABP5 gene_id:56344|Hs108|chr19 ( 173) 767 132.8 1.3e-31 CCDS8166.1 CABP4 gene_id:57010|Hs108|chr11 ( 275) 722 125.8 2.7e-29 CCDS73333.1 CABP4 gene_id:57010|Hs108|chr11 ( 170) 703 122.5 1.6e-28 CCDS1832.1 CALM2 gene_id:805|Hs108|chr2 ( 149) 403 74.4 4.2e-14 CCDS33061.1 CALM3 gene_id:808|Hs108|chr19 ( 149) 403 74.4 4.2e-14 CCDS9892.1 CALM1 gene_id:801|Hs108|chr14 ( 149) 403 74.4 4.2e-14 CCDS7069.1 CALML3 gene_id:810|Hs108|chr10 ( 149) 391 72.5 1.6e-13 >>CCDS8170.1 CABP2 gene_id:51475|Hs108|chr11 (220 aa) initn: 1500 init1: 1500 opt: 1500 Z-score: 1313.7 bits: 250.2 E(32554): 7.5e-67 Smith-Waterman score: 1500; 100.0% identity (100.0% similar) in 220 aa overlap (1-220:1-220) 10 20 30 40 50 60 pF1KE0 MGNCAKRPWRRGPKDPLQWLGSPPRGSCPSPSSSPKEQGDPAPGVQGYSVLNSLVGPACI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MGNCAKRPWRRGPKDPLQWLGSPPRGSCPSPSSSPKEQGDPAPGVQGYSVLNSLVGPACI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 FLRPSIAATQLDRELRPEEIEELQVAFQEFDRDRDGYIGCRELGACMRTLGYMPTEMELI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 FLRPSIAATQLDRELRPEEIEELQVAFQEFDRDRDGYIGCRELGACMRTLGYMPTEMELI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EISQQISGGKVDFEDFVELMGPKLLAETADMIGVRELRDAFREFDTNGDGRISVGELRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 EISQQISGGKVDFEDFVELMGPKLLAETADMIGVRELRDAFREFDTNGDGRISVGELRAA 130 140 150 160 170 180 190 200 210 220 pF1KE0 LKALLGERLSQREVDEILQDVDLNGDGLVDFEEFVRMMSR :::::::::::::::::::::::::::::::::::::::: CCDS81 LKALLGERLSQREVDEILQDVDLNGDGLVDFEEFVRMMSR 190 200 210 220 >>CCDS9205.1 CABP1 gene_id:9478|Hs108|chr12 (227 aa) initn: 585 init1: 493 opt: 893 Z-score: 788.3 bits: 153.1 E(32554): 1.4e-37 Smith-Waterman score: 893; 61.7% identity (80.6% similar) in 227 aa overlap (1-220:1-227) 10 20 30 40 50 pF1KE0 MGNCAKRPWRRGPKDPLQWLGSPPRGSCPSPSSSPKEQGDPAPGV---QGYSVLNSLVGP ::::.: : : . : . : . . :.: . :. .:...:.:: CCDS92 MGNCVKYPLRNLSRKMCQEEQTSYMVVQTSEEGLAADAELPGPLLMLAQNCAVMHNLLGP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 ACIFLRPSIAAT-QLDRELRPEEIEELQVAFQEFDRDRDGYIGCRELGACMRTLGYMPTE :::::: ..: . : :: :::::::::. ::.:::.:.::::.::.:: ::::.:::::: CCDS92 ACIFLRKGFAENRQPDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 MELIEISQQIS---GGKVDFEDFVELMGPKLLAETADMIGVRELRDAFREFDTNGDGRIS :::::.::::. ::.:::.::::::::::::::::::::.:::::::::::::::.:: CCDS92 MELIELSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEIS 130 140 150 160 170 180 180 190 200 210 220 pF1KE0 VGELRAALKALLGERLSQREVDEILQDVDLNGDGLVDFEEFVRMMSR ..::: :.. :::.....:...::..:::::::: :::::::::::: CCDS92 TSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR 190 200 210 220 >>CCDS31913.1 CABP1 gene_id:9478|Hs108|chr12 (370 aa) initn: 519 init1: 493 opt: 827 Z-score: 728.7 bits: 142.7 E(32554): 2.9e-34 Smith-Waterman score: 827; 59.8% identity (77.7% similar) in 224 aa overlap (5-220:153-370) 10 20 30 pF1KE0 MGNCAKRPWRRGPKDPLQWLGSPPRGSCPS---- :.:: .: : . . :: :. CCDS31 RPAPREEGARGSQRVLPQAHCRPREALPAAASRPSPSSPLPPARGRDGEERGLSPALGLR 130 140 150 160 170 180 40 50 60 70 80 pF1KE0 PSSSPKEQGDPAPGVQGYSVLNSLVGPACIFLRPSIA-ATQLDRELRPEEIEELQVAFQE : . .:: .:.. : . : ::: .. : :: :::::::::. ::.: CCDS31 GSLRARGRGDSVPAA------ASEADPFLHRLRPMLSSAFGQDRSLRPEEIEELREAFRE 190 200 210 220 230 90 100 110 120 130 140 pF1KE0 FDRDRDGYIGCRELGACMRTLGYMPTEMELIEISQQIS---GGKVDFEDFVELMGPKLLA ::.:.::::.::.:: ::::.:::::::::::.::::. ::.:::.:::::::::::: CCDS31 FDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELMGPKLLA 240 250 260 270 280 290 150 160 170 180 190 200 pF1KE0 ETADMIGVRELRDAFREFDTNGDGRISVGELRAALKALLGERLSQREVDEILQDVDLNGD ::::::::.:::::::::::::::.::..::: :.. :::.....:...::..::::::: CCDS31 ETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGD 300 310 320 330 340 350 210 220 pF1KE0 GLVDFEEFVRMMSR : :::::::::::: CCDS31 GRVDFEEFVRMMSR 360 370 >>CCDS9204.1 CABP1 gene_id:9478|Hs108|chr12 (167 aa) initn: 534 init1: 493 opt: 794 Z-score: 704.3 bits: 137.1 E(32554): 6.6e-33 Smith-Waterman score: 794; 71.5% identity (89.7% similar) in 165 aa overlap (59-220:4-167) 30 40 50 60 70 80 pF1KE0 PSPSSSPKEQGDPAPGVQGYSVLNSLVGPACIFLRPSIAATQLDRELRPEEIEELQVAFQ :. : .. :: :::::::::. ::. CCDS92 MGNCV-KYPLRNLSRKDRSLRPEEIEELREAFR 10 20 30 90 100 110 120 130 140 pF1KE0 EFDRDRDGYIGCRELGACMRTLGYMPTEMELIEISQQIS---GGKVDFEDFVELMGPKLL :::.:.::::.::.:: ::::.:::::::::::.::::. ::.:::.::::::::::: CCDS92 EFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELMGPKLL 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE0 AETADMIGVRELRDAFREFDTNGDGRISVGELRAALKALLGERLSQREVDEILQDVDLNG :::::::::.:::::::::::::::.::..::: :.. :::.....:...::..:::::: CCDS92 AETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNG 100 110 120 130 140 150 210 220 pF1KE0 DGLVDFEEFVRMMSR :: :::::::::::: CCDS92 DGRVDFEEFVRMMSR 160 >>CCDS12709.1 CABP5 gene_id:56344|Hs108|chr19 (173 aa) initn: 770 init1: 454 opt: 767 Z-score: 680.8 bits: 132.8 E(32554): 1.3e-31 Smith-Waterman score: 767; 66.9% identity (87.0% similar) in 169 aa overlap (55-220:5-173) 30 40 50 60 70 80 pF1KE0 RGSCPSPSSSPKEQGDPAPGVQGYSVLNSLVGPACIFLRPSIAATQLDRELRPEEIEELQ .:::::::: .:: : .: : .:::::. CCDS12 MQFPMGPACIFLRKGIAEKQRERPLGQDEIEELR 10 20 30 90 100 110 120 130 140 pF1KE0 VAFQEFDRDRDGYIGCRELGACMRTLGYMPTEMELIEISQQIS---GGKVDFEDFVELMG :: :::.::::.:.:..:: :::.:::::::::::..::: ::.:::.:::::: CCDS12 EAFLEFDKDRDGFISCKDLGNLMRTMGYMPTEMELIELGQQIRMNLGGRVDFDDFVELMT 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE0 PKLLAETADMIGVRELRDAFREFDTNGDGRISVGELRAALKALLGERLSQREVDEILQDV :::::::: ::::.:.::::.::::::::.:.. ::. :.. ::::::. ::..:..... CCDS12 PKLLAETAGMIGVQEMRDAFKEFDTNGDGEITLVELQQAMQRLLGERLTPREISEVVREA 100 110 120 130 140 150 210 220 pF1KE0 DLNGDGLVDFEEFVRMMSR :.:::: :::::::.:::: CCDS12 DVNGDGTVDFEEFVKMMSR 160 170 >>CCDS8166.1 CABP4 gene_id:57010|Hs108|chr11 (275 aa) initn: 743 init1: 422 opt: 722 Z-score: 639.4 bits: 125.8 E(32554): 2.7e-29 Smith-Waterman score: 722; 57.0% identity (76.2% similar) in 214 aa overlap (12-220:63-274) 10 20 30 40 pF1KE0 MGNCAKRPWRRGPKDPLQWLGSPPRGSCPSPSSSPKEQGDP ::. : . ..:: .. .:...: . : CCDS81 EEPPLTRKRSKKERGLRGSRKRTGSSGEQTGPEAPGS-SNNPP-STGEGPAGAPPASPGP 40 50 60 70 80 90 50 60 70 80 90 pF1KE0 APGVQGYSVL-NSLVGPACIFLRPSIAAT-QLDRELRPEEIEELQVAFQEFDRDRDGYIG : . :.. .:: : : . . :::: :::..:::.::.::: ::::::. CCDS81 ASSRQSHRHRPDSLHDAAQRTYGPLLNRVFGKDRELGPEELDELQAAFEEFDTDRDGYIS 100 110 120 130 140 150 100 110 120 130 140 150 pF1KE0 CRELGACMRTLGYMPTEMELIEISQQIS---GGKVDFEDFVELMGPKLLAETADMIGVRE :::: ::::::::::::::.:.::.:. ::.::::.::::.:::: ::: :.:::: CCDS81 HRELGDCMRTLGYMPTEMELLEVSQHIKMRMGGRVDFEEFVELIGPKLREETAHMLGVRE 160 170 180 190 200 210 160 170 180 190 200 210 pF1KE0 LRDAFREFDTNGDGRISVGELRAALKALLGERLSQREVDEILQDVDLNGDGLVDFEEFVR :: :::::: . ::::.:.::: :. ::::: :. :.::.:..::::::: :::.::: CCDS81 LRIAFREFDRDRDGRITVAELREAVPALLGEPLAGPELDEMLREVDLNGDGTVDFDEFVM 220 230 240 250 260 270 220 pF1KE0 MMSR :.:: CCDS81 MLSRH >>CCDS73333.1 CABP4 gene_id:57010|Hs108|chr11 (170 aa) initn: 705 init1: 422 opt: 703 Z-score: 625.5 bits: 122.5 E(32554): 1.6e-28 Smith-Waterman score: 703; 71.1% identity (86.8% similar) in 152 aa overlap (72-220:18-169) 50 60 70 80 90 100 pF1KE0 APGVQGYSVLNSLVGPACIFLRPSIAATQLDRELRPEEIEELQVAFQEFDRDRDGYIGCR :::: :::..:::.::.::: ::::::. : CCDS73 MTEPWLALGTSWTLPLQDRELGPEELDELQAAFEEFDTDRDGYISHR 10 20 30 40 110 120 130 140 150 pF1KE0 ELGACMRTLGYMPTEMELIEISQQIS---GGKVDFEDFVELMGPKLLAETADMIGVRELR ::: ::::::::::::::.:.::.:. ::.::::.::::.:::: ::: :.:::::: CCDS73 ELGDCMRTLGYMPTEMELLEVSQHIKMRMGGRVDFEEFVELIGPKLREETAHMLGVRELR 50 60 70 80 90 100 160 170 180 190 200 210 pF1KE0 DAFREFDTNGDGRISVGELRAALKALLGERLSQREVDEILQDVDLNGDGLVDFEEFVRMM :::::: . ::::.:.::: :. ::::: :. :.::.:..::::::: :::.::: :. CCDS73 IAFREFDRDRDGRITVAELREAVPALLGEPLAGPELDEMLREVDLNGDGTVDFDEFVMML 110 120 130 140 150 160 220 pF1KE0 SR :: CCDS73 SRH 170 >>CCDS1832.1 CALM2 gene_id:805|Hs108|chr2 (149 aa) initn: 374 init1: 148 opt: 403 Z-score: 366.6 bits: 74.4 E(32554): 4.2e-14 Smith-Waterman score: 403; 43.0% identity (74.5% similar) in 149 aa overlap (74-219:4-147) 50 60 70 80 90 100 pF1KE0 GVQGYSVLNSLVGPACIFLRPSIAATQLDRELRPEEIEELQVAFQEFDRDRDGYIGCREL .: :.: :.. ::. ::.: :: : .:: CCDS18 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKEL 10 20 30 110 120 130 140 150 160 pF1KE0 GACMRTLGYMPTEMELIEISQQISG---GKVDFEDFVELMGPKLLAETADMIGVRELRDA :. ::.:: ::: :: .. ..... : .:: .:. .:. :. : . .:.:.: CCDS18 GTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKM----KDTDSEEEIREA 40 50 60 70 80 170 180 190 200 210 220 pF1KE0 FREFDTNGDGRISVGELRAALKALLGERLSQREVDEILQDVDLNGDGLVDFEEFVRMMSR :: :: .:.: ::..::: .. : ::.:...::::.....:..::: :..::::.::. CCDS18 FRVFDKDGNGYISAAELRHVMTNL-GEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 90 100 110 120 130 140 CCDS18 K >>CCDS33061.1 CALM3 gene_id:808|Hs108|chr19 (149 aa) initn: 374 init1: 148 opt: 403 Z-score: 366.6 bits: 74.4 E(32554): 4.2e-14 Smith-Waterman score: 403; 43.0% identity (74.5% similar) in 149 aa overlap (74-219:4-147) 50 60 70 80 90 100 pF1KE0 GVQGYSVLNSLVGPACIFLRPSIAATQLDRELRPEEIEELQVAFQEFDRDRDGYIGCREL .: :.: :.. ::. ::.: :: : .:: CCDS33 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKEL 10 20 30 110 120 130 140 150 160 pF1KE0 GACMRTLGYMPTEMELIEISQQISG---GKVDFEDFVELMGPKLLAETADMIGVRELRDA :. ::.:: ::: :: .. ..... : .:: .:. .:. :. : . .:.:.: CCDS33 GTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKM----KDTDSEEEIREA 40 50 60 70 80 170 180 190 200 210 220 pF1KE0 FREFDTNGDGRISVGELRAALKALLGERLSQREVDEILQDVDLNGDGLVDFEEFVRMMSR :: :: .:.: ::..::: .. : ::.:...::::.....:..::: :..::::.::. CCDS33 FRVFDKDGNGYISAAELRHVMTNL-GEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 90 100 110 120 130 140 CCDS33 K >>CCDS9892.1 CALM1 gene_id:801|Hs108|chr14 (149 aa) initn: 374 init1: 148 opt: 403 Z-score: 366.6 bits: 74.4 E(32554): 4.2e-14 Smith-Waterman score: 403; 43.0% identity (74.5% similar) in 149 aa overlap (74-219:4-147) 50 60 70 80 90 100 pF1KE0 GVQGYSVLNSLVGPACIFLRPSIAATQLDRELRPEEIEELQVAFQEFDRDRDGYIGCREL .: :.: :.. ::. ::.: :: : .:: CCDS98 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKEL 10 20 30 110 120 130 140 150 160 pF1KE0 GACMRTLGYMPTEMELIEISQQISG---GKVDFEDFVELMGPKLLAETADMIGVRELRDA :. ::.:: ::: :: .. ..... : .:: .:. .:. :. : . .:.:.: CCDS98 GTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKM----KDTDSEEEIREA 40 50 60 70 80 170 180 190 200 210 220 pF1KE0 FREFDTNGDGRISVGELRAALKALLGERLSQREVDEILQDVDLNGDGLVDFEEFVRMMSR :: :: .:.: ::..::: .. : ::.:...::::.....:..::: :..::::.::. CCDS98 FRVFDKDGNGYISAAELRHVMTNL-GEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 90 100 110 120 130 140 CCDS98 K 220 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:13:54 2016 done: Thu Nov 3 18:13:54 2016 Total Scan time: 2.480 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]