Result of FASTA (ccds) for
pF1KE0269
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0269, 433 aa
1>>>pF1KE0269 433 - 433 aa - 433 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7234+/-0.000823; mu= 12.3038+/- 0.050
mean_var=119.8727+/-23.207, 0's: 0 Z-trim(111.7): 16 B-trim: 0 in 0/51
Lambda= 0.117142
statistics sampled from 12544 (12560) to 12544 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.386), width: 16
Scan time: 3.310
The best scores are: opt bits E(32554)
CCDS13920.1 APOL5 gene_id:80831|Hs108|chr22 ( 433) 2902 501.2 8.2e-142
CCDS13919.1 APOL6 gene_id:80830|Hs108|chr22 ( 343) 626 116.5 4.2e-26
CCDS43014.1 APOL2 gene_id:23780|Hs108|chr22 ( 337) 460 88.4 1.2e-17
CCDS13922.1 APOL3 gene_id:80833|Hs108|chr22 ( 402) 447 86.3 6.1e-17
CCDS46702.1 APOL1 gene_id:8542|Hs108|chr22 ( 380) 376 74.3 2.4e-13
CCDS13926.1 APOL1 gene_id:8542|Hs108|chr22 ( 398) 376 74.3 2.5e-13
CCDS13925.1 APOL1 gene_id:8542|Hs108|chr22 ( 414) 376 74.3 2.6e-13
CCDS74851.1 APOL4 gene_id:80832|Hs108|chr22 ( 348) 359 71.4 1.6e-12
CCDS74852.1 APOL4 gene_id:80832|Hs108|chr22 ( 351) 359 71.4 1.6e-12
CCDS13924.1 APOL3 gene_id:80833|Hs108|chr22 ( 202) 324 65.3 6.4e-11
>>CCDS13920.1 APOL5 gene_id:80831|Hs108|chr22 (433 aa)
initn: 2902 init1: 2902 opt: 2902 Z-score: 2659.5 bits: 501.2 E(32554): 8.2e-142
Smith-Waterman score: 2902; 100.0% identity (100.0% similar) in 433 aa overlap (1-433:1-433)
10 20 30 40 50 60
pF1KE0 MPCGKQGNLQVPGSKVLPGLGEGCKEMWLRKVIYGGEVWGKSPEPEFPSLVNLCQSWKIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MPCGKQGNLQVPGSKVLPGLGEGCKEMWLRKVIYGGEVWGKSPEPEFPSLVNLCQSWKIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 NLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFPLHKFELEQNIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFPLHKFELEQNIKEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 AITNIVTNVLENRSNSAARDKASRLGPLTTSHEAFGGINWSEIEAAGFCVNKCVKAIQGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 AITNIVTNVLENRSNSAARDKASRLGPLTTSHEAFGGINWSEIEAAGFCVNKCVKAIQGI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAGAG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 FLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQHHRHLPQKASQTCSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 FLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQHHRHLPQKASQTCSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 SRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPKRTVSAPRMLGHQPAPPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPKRTVSAPRMLGHQPAPPAP
370 380 390 400 410 420
430
pF1KE0 ARKGRQAPGRHRQ
:::::::::::::
CCDS13 ARKGRQAPGRHRQ
430
>>CCDS13919.1 APOL6 gene_id:80830|Hs108|chr22 (343 aa)
initn: 621 init1: 385 opt: 626 Z-score: 582.1 bits: 116.5 E(32554): 4.2e-26
Smith-Waterman score: 626; 39.5% identity (72.2% similar) in 281 aa overlap (85-363:25-302)
60 70 80 90 100 110
pF1KE0 QSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFPLHKFELE
:. . ::.:: :::.:: :: : .:.
CCDS13 MDNQAERESEAGVGLQRDEDDAPLCEDVELQDGDLSPEEKIFLREFPRLKEDLK
10 20 30 40 50
120 130 140 150 160 170
pF1KE0 QNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSLMLSATGT
:: .: .:::..: ::. .::...::.:....::::..:::::::.:.::::.::..:
CCDS13 GNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLSTAGQ
60 70 80 90 100 110
180 190 200 210 220 230
pF1KE0 GLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTSHEAFGGINWSE-IEAAGFCVNKC
::..::..:.::...:: .:. :. .: . : ... . .. . ::: . .
CCDS13 GLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKIIYNL
120 130 140 150 160 170
240 250 260 270 280 290
pF1KE0 VKAIQ-GIKDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAW
.... . :...:. ..: . .: ... .. . ::.:: :::::::..:
CCDS13 RNTLKYAKKNVRAFWKLRANPRLANATKRLLTTGQVSSRSRVQVQKAFAGTTLAMTKNAR
180 190 200 210 220 230
300 310 320 330 340 350
pF1KE0 VMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQHHRHLPQ
:.:.. ..: : :.... . ::::..::::. :::::: : .::..: .::: .. : :
CCDS13 VLGGVMSAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYKSLQQ
240 250 260 270 280 290
360 370 380 390 400 410
pF1KE0 KASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPKRTVSAPRMLG
:. : .::
CCDS13 KVR---SRARGVGKDLTGTCETEAYWKELREHVWMWLWLCVCLCVCVYVQFT
300 310 320 330 340
>>CCDS43014.1 APOL2 gene_id:23780|Hs108|chr22 (337 aa)
initn: 438 init1: 266 opt: 460 Z-score: 430.6 bits: 88.4 E(32554): 1.2e-17
Smith-Waterman score: 460; 33.9% identity (66.1% similar) in 289 aa overlap (73-356:59-337)
50 60 70 80 90 100
pF1KE0 PEPEFPSLVNLCQSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLF
. :...... : :::. .... :
CCDS43 LTDDEAWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQ-------QHRQWF
30 40 50 60 70 80
110 120 130 140 150 160
pF1KE0 LSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVT
:. :: : :::..:..: .::..:. .:. : ...:..: :..::....:::.::: :
CCDS43 LKEFPRLKRELEDHIRKLRALAEEVEQVHRGTTIANVVSNSVGTTSGILTLLGLGLAPFT
90 100 110 120 130 140
170 180 190 200 210
pF1KE0 AGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTS----HEAFGGI
: :..: :: :::::::...:. .:.: .. :: .: : :. . : :
CCDS43 EGISFVLLDTGMGLGAAAAVAGITCSVVELVNKLRARAQARNLDQSGTNVAKVMKEFVGG
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE0 NWSEIEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQ
: .. . :.. .. ::: ....: . :..: . :.. . .: .. :.
CCDS43 NTPNVLTL---VDNWYQVTQGIGRNIRAIRRARANPQLGAYAPPPHVIGRISAEGGEQVE
210 220 230 240 250
280 290 300 310 320 330
pF1KE0 RAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLE
:. :: . ::. :. ..::: .:.::. :. :. ::: .::..:.::::. :..::
CCDS43 RVVEGPAQAMSRGTMIVGAATGGILLLLDVVSLAYESKHLLEGAKSESAEELKKRAQELE
260 270 280 290 300 310
340 350 360 370 380 390
pF1KE0 QELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVA
.:. ::. :. : .:
CCDS43 GKLNFLTKIHEMLQPGQDQ
320 330
>>CCDS13922.1 APOL3 gene_id:80833|Hs108|chr22 (402 aa)
initn: 454 init1: 301 opt: 447 Z-score: 417.6 bits: 86.3 E(32554): 6.1e-17
Smith-Waterman score: 447; 32.0% identity (67.7% similar) in 300 aa overlap (55-350:104-396)
30 40 50 60 70 80
pF1KE0 KEMWLRKVIYGGEVWGKSPEPEFPSLVNLCQSWKINNLMSTVHSDEAGMLSYFLFEEL--
..:: . . ::: : : ...:
CCDS13 LEKKRFTEEATKYFRERVSPVHLQILLTNNEAWKRFVTAAELPRDEADAL-YEALKKLRT
80 90 100 110 120 130
90 100 110 120 130 140
pF1KE0 MRCDKDSMPDGNLSEEEKLFLSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVAS
. .: . . . . .. ::. :: : .....:..: .::. .. .:. : ...:.:
CCDS13 YAAIEDEYVQQKDEQFREWFLKEFPQVKRKIQESIEKLRALANGIEEVHRGCTISNVVSS
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE0 SSGAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKA
:.::.::.:.. ::.::: ::: :: :.:.:.:::::.:.:.:.:...:. .:.:. .:
CCDS13 STGAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEA
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE0 SRLGPLTTSH-EAFGGINWSEIEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVK
::: . .. ..: . . .:. .: : : ....: ..:. : ..
CCDS13 SRLTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQAR------ARAR
260 270 280 290 300
270 280 290 300 310 320
pF1KE0 NFVAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDG
:. .: .. ..:.. ::: :.. :: ...:. .:..: :. ... :::..:
CCDS13 LPVTTWRISAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEG
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE0 ARTETAEELRALAKKLEQELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSP
:.. .::::: :..::..: .::: ...:
CCDS13 AKSASAEELRRQAQELEENLMELTQIYQRLNPCHTH
370 380 390 400
>>CCDS46702.1 APOL1 gene_id:8542|Hs108|chr22 (380 aa)
initn: 327 init1: 227 opt: 376 Z-score: 353.1 bits: 74.3 E(32554): 2.4e-13
Smith-Waterman score: 376; 31.6% identity (64.5% similar) in 282 aa overlap (78-350:100-374)
50 60 70 80 90 100
pF1KE0 PSLVNLCQSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFP
: .... ::. :. . .. ::. ::
CCDS46 LTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQ--QYRNWFLKEFP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 LHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSL
: :::.::..: .::: :. .:. : ...:..: . ::.....:..::: : ::::
CCDS46 RLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEGGSL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 MLSATGTGLGAAAAITNIVTNVLENR----SNSAARDKASR-LGPLTTSHEAFGGINWSE
.: : :: .::.:.:...... ... :.: . . : : .: : : : :.
CCDS46 VLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVRE-FLGENISN
190 200 210 220 230 240
230 240 250 260 270
pF1KE0 -IEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARG--VQR
. :: . . .:: ::..: . :..: . .. . :. . : :.:
CCDS46 FLSLAG----NTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVER
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 AFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQ
. : . : :. :. . .: ..:.:. :. .. :::..::..::::::. .:..::.
CCDS46 VNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELEE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE0 ELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVAL
.:. :..... :
CCDS46 KLNILNNNYKILQADQEL
370 380
>>CCDS13926.1 APOL1 gene_id:8542|Hs108|chr22 (398 aa)
initn: 327 init1: 227 opt: 376 Z-score: 352.8 bits: 74.3 E(32554): 2.5e-13
Smith-Waterman score: 376; 31.6% identity (64.5% similar) in 282 aa overlap (78-350:118-392)
50 60 70 80 90 100
pF1KE0 PSLVNLCQSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFP
: .... ::. :. . .. ::. ::
CCDS13 LTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQ--QYRNWFLKEFP
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE0 LHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSL
: :::.::..: .::: :. .:. : ...:..: . ::.....:..::: : ::::
CCDS13 RLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEGGSL
150 160 170 180 190 200
170 180 190 200 210 220
pF1KE0 MLSATGTGLGAAAAITNIVTNVLENR----SNSAARDKASR-LGPLTTSHEAFGGINWSE
.: : :: .::.:.:...... ... :.: . . : : .: : : : :.
CCDS13 VLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVRE-FLGENISN
210 220 230 240 250 260
230 240 250 260 270
pF1KE0 -IEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARG--VQR
. :: . . .:: ::..: . :..: . .. . :. . : :.:
CCDS13 FLSLAG----NTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVER
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE0 AFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQ
. : . : :. :. . .: ..:.:. :. .. :::..::..::::::. .:..::.
CCDS13 VNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELEE
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE0 ELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVAL
.:. :..... :
CCDS13 KLNILNNNYKILQADQEL
390
>>CCDS13925.1 APOL1 gene_id:8542|Hs108|chr22 (414 aa)
initn: 327 init1: 227 opt: 376 Z-score: 352.6 bits: 74.3 E(32554): 2.6e-13
Smith-Waterman score: 376; 31.6% identity (64.5% similar) in 282 aa overlap (78-350:134-408)
50 60 70 80 90 100
pF1KE0 PSLVNLCQSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFP
: .... ::. :. . .. ::. ::
CCDS13 LTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQ--QYRNWFLKEFP
110 120 130 140 150 160
110 120 130 140 150 160
pF1KE0 LHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSL
: :::.::..: .::: :. .:. : ...:..: . ::.....:..::: : ::::
CCDS13 RLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEGGSL
170 180 190 200 210 220
170 180 190 200 210 220
pF1KE0 MLSATGTGLGAAAAITNIVTNVLENR----SNSAARDKASR-LGPLTTSHEAFGGINWSE
.: : :: .::.:.:...... ... :.: . . : : .: : : : :.
CCDS13 VLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVRE-FLGENISN
230 240 250 260 270 280
230 240 250 260 270
pF1KE0 -IEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARG--VQR
. :: . . .:: ::..: . :..: . .. . :. . : :.:
CCDS13 FLSLAG----NTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVER
290 300 310 320 330
280 290 300 310 320 330
pF1KE0 AFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQ
. : . : :. :. . .: ..:.:. :. .. :::..::..::::::. .:..::.
CCDS13 VNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELEE
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE0 ELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVAL
.:. :..... :
CCDS13 KLNILNNNYKILQADQEL
400 410
>>CCDS74851.1 APOL4 gene_id:80832|Hs108|chr22 (348 aa)
initn: 242 init1: 137 opt: 359 Z-score: 338.1 bits: 71.4 E(32554): 1.6e-12
Smith-Waterman score: 359; 26.4% identity (63.2% similar) in 348 aa overlap (12-350:18-345)
10 20 30 40 50
pF1KE0 MPCGKQGNLQVPGSKVLPGLGEGCKEMWLRKVIYGGEVWGKSPEP-EFPSLVNL
:: : . : :. . ..:: : . :. : .. :..
CCDS74 MGSWVQLITSVGVQQNHPGWTVAGQFQE--KKRFTEEVI---EYFQKKVSPVHLKILLTS
10 20 30 40 50
60 70 80 90 100
pF1KE0 CQSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLF----LSYFPLH
..:: .. . .:: : : ...: .. : .....:. : :. ::
CCDS74 DEAWKRFVRVAELPREEADAL-YEALKNL--TPYVAIEDKDMQQKEQQFREWFLKEFPQI
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 KFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSLML
.......:..: ..:.... .: . ..:. .. .:.....:. ::: ::: :: .
CCDS74 RWKIQESIERLRVIANEIEKVH----RGCVIANVVSGSTGILSVIGVMLAPFTAGLSLSI
120 130 140 150 160
170 180 190 200 210 220
pF1KE0 SATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTSH-EAFGGINWS---EIEA
.:.:.::: :.: ..:.....:: . .:. :::: .:.. ::. : . .. .
CCDS74 TAAGVGLGIASATAGIASSIVENTYTRSAELTASRLTATSTDQLEALRDILRDITPNVLS
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE0 AGFCVNKCVKAIQGIKDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEGTTL
.. .. .: : .:.:. . .:.. : . ..: :..:. ... . :. . :
CCDS74 FALDFDEATKMIA--NDVHTLRRSKATVG-----RPLIAWRYVPINVVETL-RTRGAPTR
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE0 AMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQ
. . : .: : .: :.. :. ...:. :. ::..:.:: :: :..::..:..::.
CCDS74 IVRKVARNLGKATSGVLVVLDVVNLVQDSLDLHKGAKSESAESLRQWAQELEENLNELTH
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE0 HHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPKRTV
:. :
CCDS74 IHQSLKAG
>>CCDS74852.1 APOL4 gene_id:80832|Hs108|chr22 (351 aa)
initn: 242 init1: 137 opt: 359 Z-score: 338.1 bits: 71.4 E(32554): 1.6e-12
Smith-Waterman score: 359; 26.4% identity (63.2% similar) in 348 aa overlap (12-350:21-348)
10 20 30 40 50
pF1KE0 MPCGKQGNLQVPGSKVLPGLGEGCKEMWLRKVIYGGEVWGKSPEP-EFPSL
:: : . : :. . ..:: : . :. : .. :
CCDS74 MEGAALLKIFVVCIWVQQNHPGWTVAGQFQE--KKRFTEEVI---EYFQKKVSPVHLKIL
10 20 30 40 50
60 70 80 90 100
pF1KE0 VNLCQSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLF----LSYF
.. ..:: .. . .:: : : ...: .. : .....:. : :. :
CCDS74 LTSDEAWKRFVRVAELPREEADAL-YEALKNL--TPYVAIEDKDMQQKEQQFREWFLKEF
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 PLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGS
: .......:..: ..:.... .: . ..:. .. .:.....:. ::: ::: :
CCDS74 PQIRWKIQESIERLRVIANEIEKVH----RGCVIANVVSGSTGILSVIGVMLAPFTAGLS
120 130 140 150 160
170 180 190 200 210 220
pF1KE0 LMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTSH-EAFGGINWS---E
: ..:.:.::: :.: ..:.....:: . .:. :::: .:.. ::. : . .
CCDS74 LSITAAGVGLGIASATAGIASSIVENTYTRSAELTASRLTATSTDQLEALRDILRDITPN
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE0 IEAAGFCVNKCVKAIQGIKDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEG
. . .. .. .: : .:.:. . .:.. : . ..: :..:. ... . :. .
CCDS74 VLSFALDFDEATKMIA--NDVHTLRRSKATVG-----RPLIAWRYVPINVVETL-RTRGA
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE0 TTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDR
: . . : .: : .: :.. :. ...:. :. ::..:.:: :: :..::..:..
CCDS74 PTRIVRKVARNLGKATSGVLVVLDVVNLVQDSLDLHKGAKSESAESLRQWAQELEENLNE
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE0 LTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPK
::. :. :
CCDS74 LTHIHQSLKAG
350
>>CCDS13924.1 APOL3 gene_id:80833|Hs108|chr22 (202 aa)
initn: 336 init1: 183 opt: 324 Z-score: 309.5 bits: 65.3 E(32554): 6.4e-11
Smith-Waterman score: 324; 34.2% identity (69.3% similar) in 202 aa overlap (151-350:1-196)
130 140 150 160 170 180
pF1KE0 NTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAA
:.. ::.::: ::: :: :.:.:.:::::.
CCDS13 MSLAGLVLAPFTAGTSLALTAAGVGLGAAS
10 20 30
190 200 210 220 230
pF1KE0 AITNIVTNVLENRSNSAARDKASRLGPLTTSH-EAFGGINWSEIEAAGFCVNKCVKAIQG
:.:.:.:...:. .:.:. .:::: . .. ..: . . .:. .: :
CCDS13 AVTGITTSIVEHSYTSSAEAEASRLTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQT
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE0 I-KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAG
: ....: ..:. : .. :. .: .. ..:.. ::: :.. :: ...:.
CCDS13 IGSEIRAIRQAR------ARARLPVTTWRISAGSGGQAERTIAGTTRAVSRGARILSATT
100 110 120 130 140
300 310 320 330 340 350
pF1KE0 AGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQHHRHLPQKASQTC
.:..: :. ... :::..::.. .::::: :..::..: .::: ...:
CCDS13 SGIFLALDVVNLVYESKHLHEGAKSASAEELRRQAQELEENLMELTQIYQRLNPCHTH
150 160 170 180 190 200
360 370 380 390 400 410
pF1KE0 SSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPKRTVSAPRMLGHQPAPP
433 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 18:12:35 2016 done: Thu Nov 3 18:12:36 2016
Total Scan time: 3.310 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]