FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0274, 109 aa 1>>>pF1KE0274 109 - 109 aa - 109 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0673+/-0.00034; mu= 12.2436+/- 0.021 mean_var=84.2401+/-16.496, 0's: 0 Z-trim(116.0): 101 B-trim: 69 in 3/51 Lambda= 0.139738 statistics sampled from 26625 (26806) to 26625 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.314), width: 16 Scan time: 4.500 The best scores are: opt bits E(85289) NP_001091091 (OMIM: 164795) oncomodulin-1 [Homo sa ( 109) 693 148.5 2e-36 XP_011513787 (OMIM: 164795) PREDICTED: oncomodulin ( 109) 693 148.5 2e-36 NP_001302461 (OMIM: 168890) parvalbumin alpha [Hom ( 110) 361 81.6 2.9e-16 NP_002845 (OMIM: 168890) parvalbumin alpha [Homo s ( 110) 361 81.6 2.9e-16 NP_001316853 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 149 38.8 0.0021 NP_001316852 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 149 38.8 0.0021 NP_001292555 (OMIM: 114182,616249) calmodulin isof ( 113) 149 38.8 0.0021 NP_001292554 (OMIM: 114182,616249) calmodulin isof ( 113) 149 38.8 0.0021 NP_001316854 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 149 38.8 0.0021 NP_001316855 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 149 38.8 0.0021 NP_001316850 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 149 38.8 0.0021 NP_003271 (OMIM: 191040,611879,613243) troponin C, ( 161) 150 39.2 0.0024 NP_008819 (OMIM: 114180,614916,616247) calmodulin ( 149) 149 38.9 0.0026 NP_001734 (OMIM: 114182,616249) calmodulin isoform ( 149) 149 38.9 0.0026 NP_001316851 (OMIM: 114183) calmodulin isoform 1 [ ( 149) 149 38.9 0.0026 NP_005175 (OMIM: 114183) calmodulin isoform 1 [Hom ( 149) 149 38.9 0.0026 XP_006720321 (OMIM: 114180,614916,616247) PREDICTE ( 150) 149 39.0 0.0026 NP_001292553 (OMIM: 114182,616249) calmodulin isof ( 197) 149 39.1 0.0032 NP_005176 (OMIM: 114184) calmodulin-like protein 3 ( 149) 143 37.7 0.006 XP_011527333 (OMIM: 191039) PREDICTED: troponin C, ( 145) 142 37.5 0.0068 NP_003270 (OMIM: 191039) troponin C, skeletal musc ( 160) 142 37.6 0.0073 NP_001317242 (OMIM: 610171) calmodulin-like protei ( 164) 141 37.4 0.0085 NP_619650 (OMIM: 610171) calmodulin-like protein 6 ( 181) 141 37.4 0.0092 XP_005244786 (OMIM: 610171) PREDICTED: calmodulin- ( 203) 141 37.5 0.0099 >>NP_001091091 (OMIM: 164795) oncomodulin-1 [Homo sapien (109 aa) initn: 693 init1: 693 opt: 693 Z-score: 774.8 bits: 148.5 E(85289): 2e-36 Smith-Waterman score: 693; 98.2% identity (100.0% similar) in 109 aa overlap (1-109:1-109) 10 20 30 40 50 60 pF1KE0 MSITDVLSADDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDVFRFIDNDQSGYLD :::::::::::::::::::.:::::::::::::::::::::.:::::::::::::::::: NP_001 MSITDVLSADDIAAALQECRDPDTFEPQKFFQTSGLSKMSANQVKDVFRFIDNDQSGYLD 10 20 30 40 50 60 70 80 90 100 pF1KE0 EEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVHS ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVHS 70 80 90 100 >>XP_011513787 (OMIM: 164795) PREDICTED: oncomodulin-1 i (109 aa) initn: 693 init1: 693 opt: 693 Z-score: 774.8 bits: 148.5 E(85289): 2e-36 Smith-Waterman score: 693; 98.2% identity (100.0% similar) in 109 aa overlap (1-109:1-109) 10 20 30 40 50 60 pF1KE0 MSITDVLSADDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDVFRFIDNDQSGYLD :::::::::::::::::::.:::::::::::::::::::::.:::::::::::::::::: XP_011 MSITDVLSADDIAAALQECRDPDTFEPQKFFQTSGLSKMSANQVKDVFRFIDNDQSGYLD 10 20 30 40 50 60 70 80 90 100 pF1KE0 EEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVHS ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVHS 70 80 90 100 >>NP_001302461 (OMIM: 168890) parvalbumin alpha [Homo sa (110 aa) initn: 422 init1: 361 opt: 361 Z-score: 413.1 bits: 81.6 E(85289): 2.9e-16 Smith-Waterman score: 361; 51.4% identity (81.3% similar) in 107 aa overlap (1-107:1-107) 10 20 30 40 50 60 pF1KE0 MSITDVLSADDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDVFRFIDNDQSGYLD ::.::.:.:.:: :. . :.:. .:::: ::.: ::..:: ::...:.:.::... NP_001 MSMTDLLNAEDIKKAVGAFSATDSFDHKKFFQMVGLKKKSADDVKKVFHMLDKDKSGFIE 10 20 30 40 50 60 70 80 90 100 pF1KE0 EEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVHS :.:: :.:. : ::.:. .::: ::::.:.:::::::..::. .: NP_001 EDELGFILKGFSPDARDLSAKETKMLMAAGDKDGDGKIGVDEFSTLVAES 70 80 90 100 110 >>NP_002845 (OMIM: 168890) parvalbumin alpha [Homo sapie (110 aa) initn: 422 init1: 361 opt: 361 Z-score: 413.1 bits: 81.6 E(85289): 2.9e-16 Smith-Waterman score: 361; 51.4% identity (81.3% similar) in 107 aa overlap (1-107:1-107) 10 20 30 40 50 60 pF1KE0 MSITDVLSADDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDVFRFIDNDQSGYLD ::.::.:.:.:: :. . :.:. .:::: ::.: ::..:: ::...:.:.::... NP_002 MSMTDLLNAEDIKKAVGAFSATDSFDHKKFFQMVGLKKKSADDVKKVFHMLDKDKSGFIE 10 20 30 40 50 60 70 80 90 100 pF1KE0 EEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVHS :.:: :.:. : ::.:. .::: ::::.:.:::::::..::. .: NP_002 EDELGFILKGFSPDARDLSAKETKMLMAAGDKDGDGKIGVDEFSTLVAES 70 80 90 100 110 >>NP_001316853 (OMIM: 114183) calmodulin isoform 2 [Homo (113 aa) initn: 173 init1: 90 opt: 149 Z-score: 181.9 bits: 38.8 E(85289): 0.0021 Smith-Waterman score: 149; 32.4% identity (70.6% similar) in 68 aa overlap (40-107:46-110) 10 20 30 40 50 60 pF1KE0 DDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDVFRFIDNDQSGYLDEEELKFFLQ : .....:: .:.: .::.. ::. . NP_001 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 20 30 40 50 60 70 70 80 90 100 pF1KE0 KFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVHS .. ...::. :. .. :: ::::... ::: .:. NP_001 NL---GEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 80 90 100 110 >>NP_001316852 (OMIM: 114183) calmodulin isoform 2 [Homo (113 aa) initn: 173 init1: 90 opt: 149 Z-score: 181.9 bits: 38.8 E(85289): 0.0021 Smith-Waterman score: 149; 32.4% identity (70.6% similar) in 68 aa overlap (40-107:46-110) 10 20 30 40 50 60 pF1KE0 DDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDVFRFIDNDQSGYLDEEELKFFLQ : .....:: .:.: .::.. ::. . NP_001 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 20 30 40 50 60 70 70 80 90 100 pF1KE0 KFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVHS .. ...::. :. .. :: ::::... ::: .:. NP_001 NL---GEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 80 90 100 110 >>NP_001292555 (OMIM: 114182,616249) calmodulin isoform (113 aa) initn: 173 init1: 90 opt: 149 Z-score: 181.9 bits: 38.8 E(85289): 0.0021 Smith-Waterman score: 149; 32.4% identity (70.6% similar) in 68 aa overlap (40-107:46-110) 10 20 30 40 50 60 pF1KE0 DDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDVFRFIDNDQSGYLDEEELKFFLQ : .....:: .:.: .::.. ::. . NP_001 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 20 30 40 50 60 70 70 80 90 100 pF1KE0 KFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVHS .. ...::. :. .. :: ::::... ::: .:. NP_001 NL---GEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 80 90 100 110 >>NP_001292554 (OMIM: 114182,616249) calmodulin isoform (113 aa) initn: 173 init1: 90 opt: 149 Z-score: 181.9 bits: 38.8 E(85289): 0.0021 Smith-Waterman score: 149; 32.4% identity (70.6% similar) in 68 aa overlap (40-107:46-110) 10 20 30 40 50 60 pF1KE0 DDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDVFRFIDNDQSGYLDEEELKFFLQ : .....:: .:.: .::.. ::. . NP_001 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 20 30 40 50 60 70 70 80 90 100 pF1KE0 KFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVHS .. ...::. :. .. :: ::::... ::: .:. NP_001 NL---GEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 80 90 100 110 >>NP_001316854 (OMIM: 114183) calmodulin isoform 2 [Homo (113 aa) initn: 173 init1: 90 opt: 149 Z-score: 181.9 bits: 38.8 E(85289): 0.0021 Smith-Waterman score: 149; 32.4% identity (70.6% similar) in 68 aa overlap (40-107:46-110) 10 20 30 40 50 60 pF1KE0 DDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDVFRFIDNDQSGYLDEEELKFFLQ : .....:: .:.: .::.. ::. . NP_001 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 20 30 40 50 60 70 70 80 90 100 pF1KE0 KFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVHS .. ...::. :. .. :: ::::... ::: .:. NP_001 NL---GEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 80 90 100 110 >>NP_001316855 (OMIM: 114183) calmodulin isoform 2 [Homo (113 aa) initn: 173 init1: 90 opt: 149 Z-score: 181.9 bits: 38.8 E(85289): 0.0021 Smith-Waterman score: 149; 32.4% identity (70.6% similar) in 68 aa overlap (40-107:46-110) 10 20 30 40 50 60 pF1KE0 DDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDVFRFIDNDQSGYLDEEELKFFLQ : .....:: .:.: .::.. ::. . NP_001 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 20 30 40 50 60 70 70 80 90 100 pF1KE0 KFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVHS .. ...::. :. .. :: ::::... ::: .:. NP_001 NL---GEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 80 90 100 110 109 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:02:55 2016 done: Thu Nov 3 18:02:56 2016 Total Scan time: 4.500 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]