FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0286, 69 aa 1>>>pF1KE0286 69 - 69 aa - 69 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9719+/-0.000272; mu= 8.3636+/- 0.017 mean_var=55.8965+/-11.332, 0's: 0 Z-trim(120.0): 15 B-trim: 1451 in 1/49 Lambda= 0.171547 statistics sampled from 34788 (34803) to 34788 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.408), width: 16 Scan time: 3.590 The best scores are: opt bits E(85289) NP_001032588 (OMIM: 615243) beta-defensin 114 prec ( 69) 499 130.6 2e-31 NP_061131 (OMIM: 606611) beta-defensin 103 precurs ( 67) 122 37.3 0.0024 >>NP_001032588 (OMIM: 615243) beta-defensin 114 precurso (69 aa) initn: 499 init1: 499 opt: 499 Z-score: 685.1 bits: 130.6 E(85289): 2e-31 Smith-Waterman score: 499; 100.0% identity (100.0% similar) in 69 aa overlap (1-69:1-69) 10 20 30 40 50 60 pF1KE0 MRIFYYLHFLCYVTFILPATCTLVNADRCTKRYGRCKRDCLESEKQIDICSLPRKICCTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRIFYYLHFLCYVTFILPATCTLVNADRCTKRYGRCKRDCLESEKQIDICSLPRKICCTE 10 20 30 40 50 60 pF1KE0 KLYEEDDMF ::::::::: NP_001 KLYEEDDMF >>NP_061131 (OMIM: 606611) beta-defensin 103 precursor [ (67 aa) initn: 139 init1: 74 opt: 122 Z-score: 181.0 bits: 37.3 E(85289): 0.0024 Smith-Waterman score: 122; 34.8% identity (57.6% similar) in 66 aa overlap (1-61:1-66) 10 20 30 40 50 pF1KE0 MRIFYYLHFLCYVTFI-LPATCTLVNADR---CTKRYGRCKR-DCLESEKQIDICSLPRK ::: : : : .. .. .:. ..:. . : : ::: .:: .:.:: :: . NP_061 MRIHYLLFALLFLFLVPVPGHGGIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGR 10 20 30 40 50 60 60 pF1KE0 ICCTEKLYEEDDMF :: .: NP_061 KCCRRKK 69 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 17:41:18 2016 done: Thu Nov 3 17:41:19 2016 Total Scan time: 3.590 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]