FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0295, 236 aa 1>>>pF1KE0295 236 - 236 aa - 236 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0881+/-0.000701; mu= 15.1697+/- 0.042 mean_var=60.7294+/-12.310, 0's: 0 Z-trim(108.9): 22 B-trim: 0 in 0/51 Lambda= 0.164579 statistics sampled from 10536 (10552) to 10536 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.324), width: 16 Scan time: 2.430 The best scores are: opt bits E(32554) CCDS35437.1 TREX2 gene_id:11219|Hs108|chrX ( 236) 1592 386.0 1.1e-107 CCDS59451.1 TREX1 gene_id:11277|Hs108|chr3 ( 304) 605 151.7 4.9e-37 CCDS2769.1 TREX1 gene_id:11277|Hs108|chr3 ( 314) 605 151.7 5.1e-37 CCDS43086.1 TREX1 gene_id:11277|Hs108|chr3 ( 369) 605 151.8 5.8e-37 >>CCDS35437.1 TREX2 gene_id:11219|Hs108|chrX (236 aa) initn: 1592 init1: 1592 opt: 1592 Z-score: 2046.5 bits: 386.0 E(32554): 1.1e-107 Smith-Waterman score: 1592; 100.0% identity (100.0% similar) in 236 aa overlap (1-236:1-236) 10 20 30 40 50 60 pF1KE0 MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENPEHDESGALVLPRVLDKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENPEHDESGALVLPRVLDKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TLCMCPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRTLQAFLSRQAGPICLVAHNGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 TLCMCPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRTLQAFLSRQAGPICLVAHNGF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DYDFPLLCAELRRLGARLPRDTVCLDTLPALRGLDRAHSHGTRARGRQGYSLGSLFHRYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 DYDFPLLCAELRRLGARLPRDTVCLDTLPALRGLDRAHSHGTRARGRQGYSLGSLFHRYF 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 RAEPSAAHSAEGDVHTLLLIFLHRAAELLAWADEQARGWAHIEPMYLPPDDPSLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 RAEPSAAHSAEGDVHTLLLIFLHRAAELLAWADEQARGWAHIEPMYLPPDDPSLEA 190 200 210 220 230 >>CCDS59451.1 TREX1 gene_id:11277|Hs108|chr3 (304 aa) initn: 412 init1: 412 opt: 605 Z-score: 778.3 bits: 151.7 E(32554): 4.9e-37 Smith-Waterman score: 605; 46.2% identity (68.2% similar) in 223 aa overlap (8-226:2-223) 10 20 30 40 50 pF1KE0 MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENPEHDESGALVLP---RVL .:..:.:.:::::: .:...:: :.:::: .::.: ... ..: ::. CCDS59 MQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPPPRVV 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 DKLTLCMCPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRTLQAFLSRQAGPICLVAH :::.::. : . . ::::::::. :: . :: .. : ::: :: : ::::: CCDS59 DKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAH 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 NGFDYDFPLLCAELRRLGARLPRD-TVCLDTLPALRGLDRAHSHGTRARGRQGYSLGSLF :: :::::: ::: :: : . :.:.. ::..:.:: : . .. :..:::::.. CCDS59 NGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHG-PRKSYSLGSIY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 HRYFRAEPSAAHSAEGDVHTLLLIFLHRAAELLAWADEQARGWAHIEPMYLPPDDPSLEA : . : .:.::::: .:: : : :: :.: .:: .. :.::: CCDS59 TRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASARTKP 180 190 200 210 220 230 CCDS59 RPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDPGALSREGLLAPLGLLAILTLAVAT 240 250 260 270 280 290 >>CCDS2769.1 TREX1 gene_id:11277|Hs108|chr3 (314 aa) initn: 412 init1: 412 opt: 605 Z-score: 778.1 bits: 151.7 E(32554): 5.1e-37 Smith-Waterman score: 605; 46.2% identity (68.2% similar) in 223 aa overlap (8-226:12-233) 10 20 30 40 50 pF1KE0 MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENPEHDESGALVLP-- .:..:.:.:::::: .:...:: :.:::: .::.: ... ..: CCDS27 MGSQALPPGPMQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 -RVLDKLTLCMCPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRTLQAFLSRQAGPIC ::.:::.::. : . . ::::::::. :: . :: .. : ::: :: : : CCDS27 PRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWC 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 LVAHNGFDYDFPLLCAELRRLGARLPRD-TVCLDTLPALRGLDRAHSHGTRARGRQGYSL :::::: :::::: ::: :: : . :.:.. ::..:.:: : . .. :..::: CCDS27 LVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHG-PRKSYSL 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 GSLFHRYFRAEPSAAHSAEGDVHTLLLIFLHRAAELLAWADEQARGWAHIEPMYLPPDDP ::.. : . : .:.::::: .:: : : :: :.: .:: .. :.::: CCDS27 GSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASA 180 190 200 210 220 230 pF1KE0 SLEA CCDS27 RTKPRPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDPGALSREGLLAPLGLLAILTL 240 250 260 270 280 290 >>CCDS43086.1 TREX1 gene_id:11277|Hs108|chr3 (369 aa) initn: 412 init1: 412 opt: 605 Z-score: 777.1 bits: 151.8 E(32554): 5.8e-37 Smith-Waterman score: 605; 46.2% identity (68.2% similar) in 223 aa overlap (8-226:67-288) 10 20 30 pF1KE0 MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHR .:..:.:.:::::: .:...:: :.:::: CCDS43 THTPTPCSSPGSAAGTYPTMGSQALPPGPMQTLIFFDMEATGLPFSQPKVTELCLLAVHR 40 50 60 70 80 90 40 50 60 70 80 90 pF1KE0 SSLENPEHDESGALVLP---RVLDKLTLCMCPERPFTAKASEITGLSSEGLARCRKAGFD .::.: ... ..: ::.:::.::. : . . ::::::::. :: . :: CCDS43 CALESPPTSQGPPPTVPPPPRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFD 100 110 120 130 140 150 100 110 120 130 140 150 pF1KE0 GAVVRTLQAFLSRQAGPICLVAHNGFDYDFPLLCAELRRLGARLPRD-TVCLDTLPALRG .. : ::: :: : ::::::: :::::: ::: :: : . :.:.. ::.. CCDS43 DNLANLLLAFLRRQPQPWCLVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKA 160 170 180 190 200 210 160 170 180 190 200 210 pF1KE0 LDRAHSHGTRARGRQGYSLGSLFHRYFRAEPSAAHSAEGDVHTLLLIFLHRAAELLAWAD :.:: : . .. :..:::::.. : . : .:.::::: .:: : : :: :.: CCDS43 LERASSPSEHG-PRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVD 220 230 240 250 260 270 220 230 pF1KE0 EQARGWAHIEPMYLPPDDPSLEA .:: .. :.::: CCDS43 AHARPFGTIRPMYGVTASARTKPRPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDPG 280 290 300 310 320 330 236 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 17:28:40 2016 done: Thu Nov 3 17:28:41 2016 Total Scan time: 2.430 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]