Result of FASTA (omim) for
pF1KE0297
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0297, 1586 aa
1>>>pF1KE0297 1586 - 1586 aa - 1586 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.4549+/-0.000494; mu= -20.3156+/- 0.031
mean_var=613.8238+/-132.810, 0's: 0 Z-trim(122.1): 1155 B-trim: 0 in 0/56
Lambda= 0.051767
statistics sampled from 38267 (39726) to 38267 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.466), width: 16
Scan time: 19.410
The best scores are: opt bits E(85289)
NP_005261 (OMIM: 165230,610829,615849) zinc finger (1586) 10843 826.6 0
XP_011509271 (OMIM: 165230,610829,615849) PREDICTE (1670) 10563 805.7 0
XP_011509272 (OMIM: 165230,610829,615849) PREDICTE (1539) 10551 804.7 0
XP_011509274 (OMIM: 165230,610829,615849) PREDICTE (1553) 10551 804.7 0
XP_011509273 (OMIM: 165230,610829,615849) PREDICTE (1521) 10428 795.5 0
XP_011509275 (OMIM: 165230,610829,615849) PREDICTE (1461) 9983 762.3 0
XP_011509276 (OMIM: 165230,610829,615849) PREDICTE (1444) 8138 624.5 2e-177
XP_006712485 (OMIM: 165230,610829,615849) PREDICTE (1569) 8139 624.6 2e-177
XP_016859307 (OMIM: 165230,610829,615849) PREDICTE (1653) 8139 624.6 2.1e-177
XP_011513576 (OMIM: 146510,165240,174200,174700,17 (1521) 2500 203.5 1.2e-50
XP_016867486 (OMIM: 146510,165240,174200,174700,17 (1579) 2500 203.5 1.2e-50
NP_000159 (OMIM: 146510,165240,174200,174700,17570 (1580) 2500 203.5 1.2e-50
NP_001153517 (OMIM: 165220) zinc finger protein GL ( 978) 1207 106.7 9.8e-22
NP_001161081 (OMIM: 165220) zinc finger protein GL (1065) 1207 106.8 1e-21
NP_005260 (OMIM: 165220) zinc finger protein GLI1 (1106) 1207 106.8 1.1e-21
XP_011536491 (OMIM: 165220) PREDICTED: zinc finger (1106) 1207 106.8 1.1e-21
XP_011516067 (OMIM: 610192,610199) PREDICTED: zinc ( 868) 991 90.6 6.5e-17
XP_011516066 (OMIM: 610192,610199) PREDICTED: zinc ( 930) 991 90.6 6.8e-17
NP_001035878 (OMIM: 610192,610199) zinc finger pro ( 930) 991 90.6 6.8e-17
XP_011516065 (OMIM: 610192,610199) PREDICTED: zinc ( 930) 991 90.6 6.8e-17
XP_005251443 (OMIM: 610192,610199) PREDICTED: zinc ( 775) 976 89.4 1.3e-16
XP_011516068 (OMIM: 610192,610199) PREDICTED: zinc ( 775) 976 89.4 1.3e-16
XP_016869850 (OMIM: 610192,610199) PREDICTED: zinc ( 775) 976 89.4 1.3e-16
NP_689842 (OMIM: 610192,610199) zinc finger protei ( 775) 976 89.4 1.3e-16
XP_005251445 (OMIM: 610192,610199) PREDICTED: zinc ( 708) 967 88.7 1.9e-16
XP_005251444 (OMIM: 610192,610199) PREDICTED: zinc ( 708) 967 88.7 1.9e-16
XP_011516069 (OMIM: 610192,610199) PREDICTED: zinc ( 708) 967 88.7 1.9e-16
XP_011536492 (OMIM: 165220) PREDICTED: zinc finger (1029) 887 82.8 1.6e-14
NP_671726 (OMIM: 610378) zinc finger protein GLIS1 ( 620) 775 74.3 3.6e-12
XP_016855900 (OMIM: 610378) PREDICTED: zinc finger ( 629) 775 74.3 3.6e-12
XP_016855897 (OMIM: 610378) PREDICTED: zinc finger ( 795) 775 74.4 4.3e-12
XP_016855899 (OMIM: 610378) PREDICTED: zinc finger ( 795) 775 74.4 4.3e-12
XP_016855898 (OMIM: 610378) PREDICTED: zinc finger ( 791) 768 73.9 6.2e-12
XP_005255698 (OMIM: 608539,611498) PREDICTED: zinc ( 524) 695 68.3 2e-10
NP_001305847 (OMIM: 608539,611498) zinc finger pro ( 524) 695 68.3 2e-10
NP_115964 (OMIM: 608539,611498) zinc finger protei ( 524) 695 68.3 2e-10
NP_115529 (OMIM: 608948) zinc finger protein ZIC 4 ( 334) 613 62.0 1e-08
NP_009060 (OMIM: 603073,609637) zinc finger protei ( 532) 619 62.6 1e-08
NP_001161851 (OMIM: 608948) zinc finger protein ZI ( 372) 613 62.0 1.1e-08
NP_001161850 (OMIM: 608948) zinc finger protein ZI ( 384) 613 62.0 1.1e-08
NP_003404 (OMIM: 300265,306955,314390) zinc finger ( 467) 603 61.3 2.1e-08
NP_001317590 (OMIM: 300265,306955,314390) zinc fin ( 457) 598 61.0 2.7e-08
XP_011519412 (OMIM: 603073,609637) PREDICTED: zinc ( 427) 597 60.9 2.7e-08
NP_003403 (OMIM: 600470,616602) zinc finger protei ( 447) 596 60.8 3e-08
XP_005253184 (OMIM: 603433) PREDICTED: zinc finger ( 435) 447 49.7 6.6e-05
XP_006716794 (OMIM: 610192,610199) PREDICTED: zinc ( 572) 448 49.8 7.6e-05
XP_005251446 (OMIM: 610192,610199) PREDICTED: zinc ( 583) 448 49.9 7.7e-05
XP_011516071 (OMIM: 610192,610199) PREDICTED: zinc ( 591) 448 49.9 7.8e-05
XP_016873745 (OMIM: 603433) PREDICTED: zinc finger ( 606) 447 49.8 8.4e-05
NP_001269586 (OMIM: 603433) zinc finger protein 14 ( 607) 447 49.8 8.4e-05
>>NP_005261 (OMIM: 165230,610829,615849) zinc finger pro (1586 aa)
initn: 10843 init1: 10843 opt: 10843 Z-score: 4397.7 bits: 826.6 E(85289): 0
Smith-Waterman score: 10843; 99.9% identity (100.0% similar) in 1586 aa overlap (1-1586:1-1586)
10 20 30 40 50 60
pF1KE0 METSASATASEKQEAKSGILEAAGFPDPGKKASPLVVAAAAAAAVAAQGVPQHLLPPFHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 METSASATASEKQEAKSGILEAAGFPDPGKKASPLVVAAAAAAAVAAQGVPQHLLPPFHA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVISDISLIRLSPHPAGPGESPFNAPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVISDISLIRLSPHPAGPGESPFNAPHP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 YVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 TLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDVSRFSSPRVTPRLSRKRALSISPLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDVSRFSSPRVTPRLSRKRALSISPLSD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQIL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQLSSSSNCLSDTNQNKQSSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQLSSSSNCLSDTNQNKQSSES
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 AVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKED
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTRE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 QKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 NKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 NDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 QSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAAPSAGGLQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAAPSAGGLQLR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 KHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 GLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 LGAGRPHNASSADSYDPISTDASRRSSEASQCSGGSGLLNLTPAQQYSLRAKYAAATGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LGAGRPHNASSADSYDPISTDASRRSSEASQCSGGSGLLNLTPAQQYSLRAKYAAATGGP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 PPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPLGPRRGSDGPTYGHGHAGAAPAFPHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPLGPRRGSDGPTYGHGHAGAAPAFPHE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 APGGGARRASDPVRRPDALSLPRVQRFHSTHNVNPGPLPPCADRRGLRLQSHPSTDGGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 APGGGARRASDPVRRPDALSLPRVQRFHSTHNVNPGPLPPCADRRGLRLQSHPSTDGGLA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 RGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGLPEDDLVLPDDVVQYIKAHASGALDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGLPEDDLVLPDDVVQYIKAHASGALDE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 GTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADSNVGPSAPMLGGCQLGFGAPSSLNKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADSNVGPSAPMLGGCQLGFGAPSSLNKN
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 NMPVQWNEVSSGTVDSLASQVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGLQASPGGLDS
:::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_005 NMPVQWNEVSSGTVDALASQVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGLQASPGGLDS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 TQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCPGMTTTMSPHACYGQVHPQLSPSTIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCPGMTTTMSPHACYGQVHPQLSPSTIS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE0 GALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTMGNRHRELGVPNSALAGVPPPHPVQS
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
NP_005 GALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTMGNRHRELGVPDSALAGVPPPHPVQS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE0 YPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPT
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE0 GRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAP
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE0 DHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTV
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE0 DSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGI
1510 1520 1530 1540 1550 1560
1570 1580
pF1KE0 SNMAVGDMSSMLTSLAEESKFLNMMT
::::::::::::::::::::::::::
NP_005 SNMAVGDMSSMLTSLAEESKFLNMMT
1570 1580
>>XP_011509271 (OMIM: 165230,610829,615849) PREDICTED: z (1670 aa)
initn: 10551 init1: 10551 opt: 10563 Z-score: 4284.4 bits: 805.7 E(85289): 0
Smith-Waterman score: 10563; 98.7% identity (99.0% similar) in 1565 aa overlap (22-1586:110-1670)
10 20 30 40 50
pF1KE0 METSASATASEKQEAKSGILEAAGFPDPGKKASPLVVAAAAAAAVAAQGVP
::: : . :.:: .::. ::
XP_011 SCSPASLGGHLMFPALQPGGPPPLLPLGSAAAG-QCPPRTAAPL---GAASLRPPRTLVP
80 90 100 110 120 130
60 70 80 90 100 110
pF1KE0 QHLLPPFHAPLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVISDISLIRLSPHPAGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHLLPPFHAPLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVISDISLIRLSPHPAGPG
140 150 160 170 180 190
120 130 140 150 160 170
pF1KE0 ESPFNAPHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQEHLKERGLFGLPAPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESPFNAPHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQEHLKERGLFGLPAPGT
200 210 220 230 240 250
180 190 200 210 220 230
pF1KE0 TPSDYYHQMTLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDVSRFSSPRVTPRLSRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPSDYYHQMTLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDVSRFSSPRVTPRLSRKR
260 270 280 290 300 310
240 250 260 270 280 290
pF1KE0 ALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHPI
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE0 NPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQLSSSSNCLSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQLSSSSNCLSDT
380 390 400 410 420 430
360 370 380 390 400 410
pF1KE0 NQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVSGHGSCGCALPLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVSGHGSCGCALPLSQ
440 450 460 470 480 490
420 430 440 450 460 470
pF1KE0 EQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFV
500 510 520 530 540 550
480 490 500 510 520 530
pF1KE0 CRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEK
560 570 580 590 600 610
540 550 560 570 580 590
pF1KE0 PYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGP
620 630 640 650 660 670
600 610 620 630 640 650
pF1KE0 DAHVTKKQRNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAHVTKKQRNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESS
680 690 700 710 720 730
660 670 680 690 700 710
pF1KE0 GLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAA
740 750 760 770 780 790
720 730 740 750 760 770
pF1KE0 PSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENF
800 810 820 830 840 850
780 790 800 810 820 830
pF1KE0 SGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFS
860 870 880 890 900 910
840 850 860 870 880 890
pF1KE0 SRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGGSGLLNLTPAQQYSLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGGSGLLNLTPAQQYSLRA
920 930 940 950 960 970
900 910 920 930 940 950
pF1KE0 KYAAATGGPPPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPLGPRRGSDGPTYGHGHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYAAATGGPPPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPLGPRRGSDGPTYGHGHA
980 990 1000 1010 1020 1030
960 970 980 990 1000 1010
pF1KE0 GAAPAFPHEAPGGGARRASDPVRRPDALSLPRVQRFHSTHNVNPGPLPPCADRRGLRLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAAPAFPHEAPGGGARRASDPVRRPDALSLPRVQRFHSTHNVNPGPLPPCADRRGLRLQS
1040 1050 1060 1070 1080 1090
1020 1030 1040 1050 1060 1070
pF1KE0 HPSTDGGLARGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGLPEDDLVLPDDVVQYIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPSTDGGLARGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGLPEDDLVLPDDVVQYIK
1100 1110 1120 1130 1140 1150
1080 1090 1100 1110 1120 1130
pF1KE0 AHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADSNVGPSAPMLGGCQLGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADSNVGPSAPMLGGCQLGF
1160 1170 1180 1190 1200 1210
1140 1150 1160 1170 1180 1190
pF1KE0 GAPSSLNKNNMPVQWNEVSSGTVDSLASQVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGL
::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
XP_011 GAPSSLNKNNMPVQWNEVSSGTVDALASQVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGL
1220 1230 1240 1250 1260 1270
1200 1210 1220 1230 1240 1250
pF1KE0 QASPGGLDSTQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCPGMTTTMSPHACYGQVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QASPGGLDSTQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCPGMTTTMSPHACYGQVH
1280 1290 1300 1310 1320 1330
1260 1270 1280 1290 1300 1310
pF1KE0 PQLSPSTISGALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTMGNRHRELGVPNSALAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
XP_011 PQLSPSTISGALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTMGNRHRELGVPDSALAG
1340 1350 1360 1370 1380 1390
1320 1330 1340 1350 1360 1370
pF1KE0 VPPPHPVQSYPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPPPHPVQSYPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQP
1400 1410 1420 1430 1440 1450
1380 1390 1400 1410 1420 1430
pF1KE0 RPPLEPSPTGRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPPLEPSPTGRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQP
1460 1470 1480 1490 1500 1510
1440 1450 1460 1470 1480 1490
pF1KE0 PPQDAGGAPDHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQPQACQDSIQPQPLPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPQDAGGAPDHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQPQACQDSIQPQPLPSP
1520 1530 1540 1550 1560 1570
1500 1510 1520 1530 1540 1550
pF1KE0 GVNQVSSTVDSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVNQVSSTVDSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSL
1580 1590 1600 1610 1620 1630
1560 1570 1580
pF1KE0 TLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT
:::::::::::::::::::::::::::::::::::
XP_011 TLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT
1640 1650 1660 1670
>>XP_011509272 (OMIM: 165230,610829,615849) PREDICTED: z (1539 aa)
initn: 10551 init1: 10551 opt: 10551 Z-score: 4280.0 bits: 804.7 E(85289): 0
Smith-Waterman score: 10551; 99.9% identity (100.0% similar) in 1537 aa overlap (50-1586:3-1539)
20 30 40 50 60 70
pF1KE0 LEAAGFPDPGKKASPLVVAAAAAAAVAAQGVPQHLLPPFHAPLPIDMRHQEGRYHYEPHS
::::::::::::::::::::::::::::::
XP_011 MLVPQHLLPPFHAPLPIDMRHQEGRYHYEPHS
10 20 30
80 90 100 110 120 130
pF1KE0 VHGVHGPPALSGSPVISDISLIRLSPHPAGPGESPFNAPHPYVNPHMEHYLRSVHSSPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHGVHGPPALSGSPVISDISLIRLSPHPAGPGESPFNAPHPYVNPHMEHYLRSVHSSPTL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE0 SMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQMTLVAGHPAPYGDLLMQSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQMTLVAGHPAPYGDLLMQSGG
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE0 AASAPHLHDYLNPVDVSRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AASAPHLHDYLNPVDVSRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAY
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE0 INNSRSSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQILSQQRGLGSAFGHTPPLIQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INNSRSSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQILSQQRGLGSAFGHTPPLIQP
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE0 SPTFLAQQPMALTSINATPTQLSSSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPTFLAQQPMALTSINATPTQLSSSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKT
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE0 EPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNC
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE0 HWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTG
400 410 420 430 440 450
500 510 520 530 540 550
pF1KE0 EKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHS
460 470 480 490 500 510
560 570 580 590 600 610
pF1KE0 NEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAG
520 530 540 550 560 570
620 630 640 650 660 670
pF1KE0 TEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDS
580 590 600 610 620 630
680 690 700 710 720 730
pF1KE0 GVEMPGTGPGSLGDLTALDDTPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVEMPGTGPGSLGDLTALDDTPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKS
640 650 660 670 680 690
740 750 760 770 780 790
pF1KE0 LKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTML
700 710 720 730 740 750
800 810 820 830 840 850
pF1KE0 SQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPIS
760 770 780 790 800 810
860 870 880 890 900 910
pF1KE0 TDASRRSSEASQCSGGSGLLNLTPAQQYSLRAKYAAATGGPPPTPLPGLERMSLRTRLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDASRRSSEASQCSGGSGLLNLTPAQQYSLRAKYAAATGGPPPTPLPGLERMSLRTRLAL
820 830 840 850 860 870
920 930 940 950 960 970
pF1KE0 LDAPERTLPAGCPRPLGPRRGSDGPTYGHGHAGAAPAFPHEAPGGGARRASDPVRRPDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDAPERTLPAGCPRPLGPRRGSDGPTYGHGHAGAAPAFPHEAPGGGARRASDPVRRPDAL
880 890 900 910 920 930
980 990 1000 1010 1020 1030
pF1KE0 SLPRVQRFHSTHNVNPGPLPPCADRRGLRLQSHPSTDGGLARGAYSPRPPSISENVAMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLPRVQRFHSTHNVNPGPLPPCADRRGLRLQSHPSTDGGLARGAYSPRPPSISENVAMEA
940 950 960 970 980 990
1040 1050 1060 1070 1080 1090
pF1KE0 VAAGVDGAGPEADLGLPEDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAAGVDGAGPEADLGLPEDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRL
1000 1010 1020 1030 1040 1050
1100 1110 1120 1130 1140 1150
pF1KE0 PSPGLHGQRRMVAADSNVGPSAPMLGGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDSLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
XP_011 PSPGLHGQRRMVAADSNVGPSAPMLGGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDALAS
1060 1070 1080 1090 1100 1110
1160 1170 1180 1190 1200 1210
pF1KE0 QVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGLQASPGGLDSTQPHLQPRSGAPSQGIPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGLQASPGGLDSTQPHLQPRSGAPSQGIPRV
1120 1130 1140 1150 1160 1170
1220 1230 1240 1250 1260 1270
pF1KE0 NYMQQLRQPVAGSQCPGMTTTMSPHACYGQVHPQLSPSTISGALNQFPQSCSNMPAKPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYMQQLRQPVAGSQCPGMTTTMSPHACYGQVHPQLSPSTISGALNQFPQSCSNMPAKPGH
1180 1190 1200 1210 1220 1230
1280 1290 1300 1310 1320 1330
pF1KE0 LGHPQQTEVAPDPTTMGNRHRELGVPNSALAGVPPPHPVQSYPQQSHHLAASMSQEGYHQ
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_011 LGHPQQTEVAPDPTTMGNRHRELGVPDSALAGVPPPHPVQSYPQQSHHLAASMSQEGYHQ
1240 1250 1260 1270 1280 1290
1340 1350 1360 1370 1380 1390
pF1KE0 VPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPTGRHRGVRAVQQQLAYARAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPTGRHRGVRAVQQQLAYARAT
1300 1310 1320 1330 1340 1350
1400 1410 1420 1430 1440 1450
pF1KE0 GHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHMYEQDGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHMYEQDGG
1360 1370 1380 1390 1400 1410
1460 1470 1480 1490 1500 1510
pF1KE0 LENLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFDAIMDDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LENLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFDAIMDDG
1420 1430 1440 1450 1460 1470
1520 1530 1540 1550 1560 1570
pF1KE0 DHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEES
1480 1490 1500 1510 1520 1530
1580
pF1KE0 KFLNMMT
:::::::
XP_011 KFLNMMT
>>XP_011509274 (OMIM: 165230,610829,615849) PREDICTED: z (1553 aa)
initn: 10551 init1: 10551 opt: 10551 Z-score: 4279.9 bits: 804.7 E(85289): 0
Smith-Waterman score: 10551; 99.9% identity (100.0% similar) in 1537 aa overlap (50-1586:17-1553)
20 30 40 50 60 70
pF1KE0 LEAAGFPDPGKKASPLVVAAAAAAAVAAQGVPQHLLPPFHAPLPIDMRHQEGRYHYEPHS
::::::::::::::::::::::::::::::
XP_011 MTEPWFTLRSVWIHGSVPQHLLPPFHAPLPIDMRHQEGRYHYEPHS
10 20 30 40
80 90 100 110 120 130
pF1KE0 VHGVHGPPALSGSPVISDISLIRLSPHPAGPGESPFNAPHPYVNPHMEHYLRSVHSSPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHGVHGPPALSGSPVISDISLIRLSPHPAGPGESPFNAPHPYVNPHMEHYLRSVHSSPTL
50 60 70 80 90 100
140 150 160 170 180 190
pF1KE0 SMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQMTLVAGHPAPYGDLLMQSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQMTLVAGHPAPYGDLLMQSGG
110 120 130 140 150 160
200 210 220 230 240 250
pF1KE0 AASAPHLHDYLNPVDVSRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AASAPHLHDYLNPVDVSRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAY
170 180 190 200 210 220
260 270 280 290 300 310
pF1KE0 INNSRSSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQILSQQRGLGSAFGHTPPLIQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INNSRSSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQILSQQRGLGSAFGHTPPLIQP
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE0 SPTFLAQQPMALTSINATPTQLSSSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPTFLAQQPMALTSINATPTQLSSSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKT
290 300 310 320 330 340
380 390 400 410 420 430
pF1KE0 EPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNC
350 360 370 380 390 400
440 450 460 470 480 490
pF1KE0 HWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTG
410 420 430 440 450 460
500 510 520 530 540 550
pF1KE0 EKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHS
470 480 490 500 510 520
560 570 580 590 600 610
pF1KE0 NEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAG
530 540 550 560 570 580
620 630 640 650 660 670
pF1KE0 TEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDS
590 600 610 620 630 640
680 690 700 710 720 730
pF1KE0 GVEMPGTGPGSLGDLTALDDTPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVEMPGTGPGSLGDLTALDDTPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKS
650 660 670 680 690 700
740 750 760 770 780 790
pF1KE0 LKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTML
710 720 730 740 750 760
800 810 820 830 840 850
pF1KE0 SQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPIS
770 780 790 800 810 820
860 870 880 890 900 910
pF1KE0 TDASRRSSEASQCSGGSGLLNLTPAQQYSLRAKYAAATGGPPPTPLPGLERMSLRTRLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDASRRSSEASQCSGGSGLLNLTPAQQYSLRAKYAAATGGPPPTPLPGLERMSLRTRLAL
830 840 850 860 870 880
920 930 940 950 960 970
pF1KE0 LDAPERTLPAGCPRPLGPRRGSDGPTYGHGHAGAAPAFPHEAPGGGARRASDPVRRPDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDAPERTLPAGCPRPLGPRRGSDGPTYGHGHAGAAPAFPHEAPGGGARRASDPVRRPDAL
890 900 910 920 930 940
980 990 1000 1010 1020 1030
pF1KE0 SLPRVQRFHSTHNVNPGPLPPCADRRGLRLQSHPSTDGGLARGAYSPRPPSISENVAMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLPRVQRFHSTHNVNPGPLPPCADRRGLRLQSHPSTDGGLARGAYSPRPPSISENVAMEA
950 960 970 980 990 1000
1040 1050 1060 1070 1080 1090
pF1KE0 VAAGVDGAGPEADLGLPEDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAAGVDGAGPEADLGLPEDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRL
1010 1020 1030 1040 1050 1060
1100 1110 1120 1130 1140 1150
pF1KE0 PSPGLHGQRRMVAADSNVGPSAPMLGGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDSLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
XP_011 PSPGLHGQRRMVAADSNVGPSAPMLGGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDALAS
1070 1080 1090 1100 1110 1120
1160 1170 1180 1190 1200 1210
pF1KE0 QVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGLQASPGGLDSTQPHLQPRSGAPSQGIPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGLQASPGGLDSTQPHLQPRSGAPSQGIPRV
1130 1140 1150 1160 1170 1180
1220 1230 1240 1250 1260 1270
pF1KE0 NYMQQLRQPVAGSQCPGMTTTMSPHACYGQVHPQLSPSTISGALNQFPQSCSNMPAKPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYMQQLRQPVAGSQCPGMTTTMSPHACYGQVHPQLSPSTISGALNQFPQSCSNMPAKPGH
1190 1200 1210 1220 1230 1240
1280 1290 1300 1310 1320 1330
pF1KE0 LGHPQQTEVAPDPTTMGNRHRELGVPNSALAGVPPPHPVQSYPQQSHHLAASMSQEGYHQ
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_011 LGHPQQTEVAPDPTTMGNRHRELGVPDSALAGVPPPHPVQSYPQQSHHLAASMSQEGYHQ
1250 1260 1270 1280 1290 1300
1340 1350 1360 1370 1380 1390
pF1KE0 VPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPTGRHRGVRAVQQQLAYARAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPTGRHRGVRAVQQQLAYARAT
1310 1320 1330 1340 1350 1360
1400 1410 1420 1430 1440 1450
pF1KE0 GHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHMYEQDGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHMYEQDGG
1370 1380 1390 1400 1410 1420
1460 1470 1480 1490 1500 1510
pF1KE0 LENLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFDAIMDDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LENLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFDAIMDDG
1430 1440 1450 1460 1470 1480
1520 1530 1540 1550 1560 1570
pF1KE0 DHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEES
1490 1500 1510 1520 1530 1540
1580
pF1KE0 KFLNMMT
:::::::
XP_011 KFLNMMT
1550
>>XP_011509273 (OMIM: 165230,610829,615849) PREDICTED: z (1521 aa)
initn: 10428 init1: 10428 opt: 10428 Z-score: 4230.4 bits: 795.5 E(85289): 0
Smith-Waterman score: 10428; 99.9% identity (100.0% similar) in 1521 aa overlap (66-1586:1-1521)
40 50 60 70 80 90
pF1KE0 VVAAAAAAAVAAQGVPQHLLPPFHAPLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVI
::::::::::::::::::::::::::::::
XP_011 MRHQEGRYHYEPHSVHGVHGPPALSGSPVI
10 20 30
100 110 120 130 140 150
pF1KE0 SDISLIRLSPHPAGPGESPFNAPHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDISLIRLSPHPAGPGESPFNAPHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQ
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE0 EHLKERGLFGLPAPGTTPSDYYHQMTLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHLKERGLFGLPAPGTTPSDYYHQMTLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDV
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE0 SRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGH
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE0 LSAGALSPAFTFPHPINPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAGALSPAFTFPHPINPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSIN
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE0 ATPTQLSSSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATPTQLSSSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQG
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE0 QVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLV
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE0 HHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYS
400 410 420 430 440 450
520 530 540 550 560 570
pF1KE0 RLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRY
460 470 480 490 500 510
580 590 600 610 620 630
pF1KE0 TDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQ
520 530 540 550 560 570
640 650 660 670 680 690
pF1KE0 AVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLT
580 590 600 610 620 630
700 710 720 730 740 750
pF1KE0 ALDDTPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALDDTPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRN
640 650 660 670 680 690
760 770 780 790 800 810
pF1KE0 TKLPPLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKLPPLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSS
700 710 720 730 740 750
820 830 840 850 860 870
pF1KE0 AYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGG
760 770 780 790 800 810
880 890 900 910 920 930
pF1KE0 SGLLNLTPAQQYSLRAKYAAATGGPPPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLLNLTPAQQYSLRAKYAAATGGPPPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPL
820 830 840 850 860 870
940 950 960 970 980 990
pF1KE0 GPRRGSDGPTYGHGHAGAAPAFPHEAPGGGARRASDPVRRPDALSLPRVQRFHSTHNVNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPRRGSDGPTYGHGHAGAAPAFPHEAPGGGARRASDPVRRPDALSLPRVQRFHSTHNVNP
880 890 900 910 920 930
1000 1010 1020 1030 1040 1050
pF1KE0 GPLPPCADRRGLRLQSHPSTDGGLARGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLPPCADRRGLRLQSHPSTDGGLARGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGL
940 950 960 970 980 990
1060 1070 1080 1090 1100 1110
pF1KE0 PEDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADS
1000 1010 1020 1030 1040 1050
1120 1130 1140 1150 1160 1170
pF1KE0 NVGPSAPMLGGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDSLASQVKPPPFPQGNLAVVQ
::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_011 NVGPSAPMLGGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDALASQVKPPPFPQGNLAVVQ
1060 1070 1080 1090 1100 1110
1180 1190 1200 1210 1220 1230
pF1KE0 QKPAFGQYPGYSPQGLQASPGGLDSTQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKPAFGQYPGYSPQGLQASPGGLDSTQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCP
1120 1130 1140 1150 1160 1170
1240 1250 1260 1270 1280 1290
pF1KE0 GMTTTMSPHACYGQVHPQLSPSTISGALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMTTTMSPHACYGQVHPQLSPSTISGALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTM
1180 1190 1200 1210 1220 1230
1300 1310 1320 1330 1340 1350
pF1KE0 GNRHRELGVPNSALAGVPPPHPVQSYPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQ
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNRHRELGVPDSALAGVPPPHPVQSYPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQ
1240 1250 1260 1270 1280 1290
1360 1370 1380 1390 1400 1410
pF1KE0 TGPMGVATAGFGLVQPRPPLEPSPTGRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGPMGVATAGFGLVQPRPPLEPSPTGRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEA
1300 1310 1320 1330 1340 1350
1420 1430 1440 1450 1460 1470
pF1KE0 VPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQ
1360 1370 1380 1390 1400 1410
1480 1490 1500 1510 1520 1530
pF1KE0 PQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLH
1420 1430 1440 1450 1460 1470
1540 1550 1560 1570 1580
pF1KE0 SLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT
1480 1490 1500 1510 1520
>>XP_011509275 (OMIM: 165230,610829,615849) PREDICTED: z (1461 aa)
initn: 9983 init1: 9983 opt: 9983 Z-score: 4051.0 bits: 762.3 E(85289): 0
Smith-Waterman score: 9983; 99.9% identity (100.0% similar) in 1461 aa overlap (126-1586:1-1461)
100 110 120 130 140 150
pF1KE0 SDISLIRLSPHPAGPGESPFNAPHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQ
::::::::::::::::::::::::::::::
XP_011 MEHYLRSVHSSPTLSMISAARGLSPADVAQ
10 20 30
160 170 180 190 200 210
pF1KE0 EHLKERGLFGLPAPGTTPSDYYHQMTLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHLKERGLFGLPAPGTTPSDYYHQMTLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDV
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE0 SRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGH
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE0 LSAGALSPAFTFPHPINPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAGALSPAFTFPHPINPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSIN
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE0 ATPTQLSSSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATPTQLSSSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQG
220 230 240 250 260 270
400 410 420 430 440 450
pF1KE0 QVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLV
280 290 300 310 320 330
460 470 480 490 500 510
pF1KE0 HHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYS
340 350 360 370 380 390
520 530 540 550 560 570
pF1KE0 RLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRY
400 410 420 430 440 450
580 590 600 610 620 630
pF1KE0 TDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQ
460 470 480 490 500 510
640 650 660 670 680 690
pF1KE0 AVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLT
520 530 540 550 560 570
700 710 720 730 740 750
pF1KE0 ALDDTPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALDDTPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRN
580 590 600 610 620 630
760 770 780 790 800 810
pF1KE0 TKLPPLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKLPPLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSS
640 650 660 670 680 690
820 830 840 850 860 870
pF1KE0 AYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGG
700 710 720 730 740 750
880 890 900 910 920 930
pF1KE0 SGLLNLTPAQQYSLRAKYAAATGGPPPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLLNLTPAQQYSLRAKYAAATGGPPPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPL
760 770 780 790 800 810
940 950 960 970 980 990
pF1KE0 GPRRGSDGPTYGHGHAGAAPAFPHEAPGGGARRASDPVRRPDALSLPRVQRFHSTHNVNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPRRGSDGPTYGHGHAGAAPAFPHEAPGGGARRASDPVRRPDALSLPRVQRFHSTHNVNP
820 830 840 850 860 870
1000 1010 1020 1030 1040 1050
pF1KE0 GPLPPCADRRGLRLQSHPSTDGGLARGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLPPCADRRGLRLQSHPSTDGGLARGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGL
880 890 900 910 920 930
1060 1070 1080 1090 1100 1110
pF1KE0 PEDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADS
940 950 960 970 980 990
1120 1130 1140 1150 1160 1170
pF1KE0 NVGPSAPMLGGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDSLASQVKPPPFPQGNLAVVQ
::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_011 NVGPSAPMLGGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDALASQVKPPPFPQGNLAVVQ
1000 1010 1020 1030 1040 1050
1180 1190 1200 1210 1220 1230
pF1KE0 QKPAFGQYPGYSPQGLQASPGGLDSTQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKPAFGQYPGYSPQGLQASPGGLDSTQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCP
1060 1070 1080 1090 1100 1110
1240 1250 1260 1270 1280 1290
pF1KE0 GMTTTMSPHACYGQVHPQLSPSTISGALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMTTTMSPHACYGQVHPQLSPSTISGALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTM
1120 1130 1140 1150 1160 1170
1300 1310 1320 1330 1340 1350
pF1KE0 GNRHRELGVPNSALAGVPPPHPVQSYPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQ
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNRHRELGVPDSALAGVPPPHPVQSYPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQ
1180 1190 1200 1210 1220 1230
1360 1370 1380 1390 1400 1410
pF1KE0 TGPMGVATAGFGLVQPRPPLEPSPTGRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGPMGVATAGFGLVQPRPPLEPSPTGRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEA
1240 1250 1260 1270 1280 1290
1420 1430 1440 1450 1460 1470
pF1KE0 VPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQ
1300 1310 1320 1330 1340 1350
1480 1490 1500 1510 1520 1530
pF1KE0 PQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLH
1360 1370 1380 1390 1400 1410
1540 1550 1560 1570 1580
pF1KE0 SLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT
1420 1430 1440 1450 1460
>>XP_011509276 (OMIM: 165230,610829,615849) PREDICTED: z (1444 aa)
initn: 8118 init1: 8118 opt: 8138 Z-score: 3306.4 bits: 624.5 E(85289): 2e-177
Smith-Waterman score: 9812; 98.7% identity (98.8% similar) in 1461 aa overlap (126-1586:1-1444)
100 110 120 130 140 150
pF1KE0 SDISLIRLSPHPAGPGESPFNAPHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQ
::::::::::::::::::::::::::::::
XP_011 MEHYLRSVHSSPTLSMISAARGLSPADVAQ
10 20 30
160 170 180 190 200 210
pF1KE0 EHLKERGLFGLPAPGTTPSDYYHQMTLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHLKERGLFGLPAPGTTPSDYYHQMTLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDV
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE0 SRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGH
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE0 LSAGALSPAFTFPHPINPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAGALSPAFTFPHPINPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSIN
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE0 ATPTQLSSSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATPTQLSSSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQ-
220 230 240 250 260
400 410 420 430 440 450
pF1KE0 QVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLV
::::::::::::::::::::::::::::::::::::::::::::
XP_011 ----------------EQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLV
270 280 290 300 310
460 470 480 490 500 510
pF1KE0 HHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYS
320 330 340 350 360 370
520 530 540 550 560 570
pF1KE0 RLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRY
380 390 400 410 420 430
580 590 600 610 620 630
pF1KE0 TDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQ
440 450 460 470 480 490
640 650 660 670 680 690
pF1KE0 AVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLT
500 510 520 530 540 550
700 710 720 730 740 750
pF1KE0 ALDDTPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALDDTPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRN
560 570 580 590 600 610
760 770 780 790 800 810
pF1KE0 TKLPPLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKLPPLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSS
620 630 640 650 660 670
820 830 840 850 860 870
pF1KE0 AYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGG
680 690 700 710 720 730
880 890 900 910 920 930
pF1KE0 SGLLNLTPAQQYSLRAKYAAATGGPPPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLLNLTPAQQYSLRAKYAAATGGPPPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPL
740 750 760 770 780 790
940 950 960 970 980 990
pF1KE0 GPRRGSDGPTYGHGHAGAAPAFPHEAPGGGARRASDPVRRPDALSLPRVQRFHSTHNVNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPRRGSDGPTYGHGHAGAAPAFPHEAPGGGARRASDPVRRPDALSLPRVQRFHSTHNVNP
800 810 820 830 840 850
1000 1010 1020 1030 1040 1050
pF1KE0 GPLPPCADRRGLRLQSHPSTDGGLARGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLPPCADRRGLRLQSHPSTDGGLARGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGL
860 870 880 890 900 910
1060 1070 1080 1090 1100 1110
pF1KE0 PEDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADS
920 930 940 950 960 970
1120 1130 1140 1150 1160 1170
pF1KE0 NVGPSAPMLGGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDSLASQVKPPPFPQGNLAVVQ
::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_011 NVGPSAPMLGGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDALASQVKPPPFPQGNLAVVQ
980 990 1000 1010 1020 1030
1180 1190 1200 1210 1220 1230
pF1KE0 QKPAFGQYPGYSPQGLQASPGGLDSTQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKPAFGQYPGYSPQGLQASPGGLDSTQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCP
1040 1050 1060 1070 1080 1090
1240 1250 1260 1270 1280 1290
pF1KE0 GMTTTMSPHACYGQVHPQLSPSTISGALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMTTTMSPHACYGQVHPQLSPSTISGALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTM
1100 1110 1120 1130 1140 1150
1300 1310 1320 1330 1340 1350
pF1KE0 GNRHRELGVPNSALAGVPPPHPVQSYPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQ
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNRHRELGVPDSALAGVPPPHPVQSYPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQ
1160 1170 1180 1190 1200 1210
1360 1370 1380 1390 1400 1410
pF1KE0 TGPMGVATAGFGLVQPRPPLEPSPTGRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGPMGVATAGFGLVQPRPPLEPSPTGRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEA
1220 1230 1240 1250 1260 1270
1420 1430 1440 1450 1460 1470
pF1KE0 VPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQ
1280 1290 1300 1310 1320 1330
1480 1490 1500 1510 1520 1530
pF1KE0 PQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLH
1340 1350 1360 1370 1380 1390
1540 1550 1560 1570 1580
pF1KE0 SLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT
1400 1410 1420 1430 1440
>>XP_006712485 (OMIM: 165230,610829,615849) PREDICTED: z (1569 aa)
initn: 8118 init1: 8118 opt: 8139 Z-score: 3306.3 bits: 624.6 E(85289): 2e-177
Smith-Waterman score: 10672; 98.8% identity (98.9% similar) in 1586 aa overlap (1-1586:1-1569)
10 20 30 40 50 60
pF1KE0 METSASATASEKQEAKSGILEAAGFPDPGKKASPLVVAAAAAAAVAAQGVPQHLLPPFHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 METSASATASEKQEAKSGILEAAGFPDPGKKASPLVVAAAAAAAVAAQGVPQHLLPPFHA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVISDISLIRLSPHPAGPGESPFNAPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVISDISLIRLSPHPAGPGESPFNAPHP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 YVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 TLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDVSRFSSPRVTPRLSRKRALSISPLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDVSRFSSPRVTPRLSRKRALSISPLSD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQIL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQLSSSSNCLSDTNQNKQSSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQLSSSSNCLSDTNQNKQSSES
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 AVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKED
:::::::::::::::::::::::::::::::::: :::::::::
XP_006 AVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQ-----------------EQLADLKED
370 380 390 400
430 440 450 460 470 480
pF1KE0 LDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTRE
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE0 QKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGC
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE0 NKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQR
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE0 NDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGA
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE0 QSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAAPSAGGLQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAAPSAGGLQLR
650 660 670 680 690 700
730 740 750 760 770 780
pF1KE0 KHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPA
710 720 730 740 750 760
790 800 810 820 830 840
pF1KE0 GLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASP
770 780 790 800 810 820
850 860 870 880 890 900
pF1KE0 LGAGRPHNASSADSYDPISTDASRRSSEASQCSGGSGLLNLTPAQQYSLRAKYAAATGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGAGRPHNASSADSYDPISTDASRRSSEASQCSGGSGLLNLTPAQQYSLRAKYAAATGGP
830 840 850 860 870 880
910 920 930 940 950 960
pF1KE0 PPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPLGPRRGSDGPTYGHGHAGAAPAFPHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPLGPRRGSDGPTYGHGHAGAAPAFPHE
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KE0 APGGGARRASDPVRRPDALSLPRVQRFHSTHNVNPGPLPPCADRRGLRLQSHPSTDGGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APGGGARRASDPVRRPDALSLPRVQRFHSTHNVNPGPLPPCADRRGLRLQSHPSTDGGLA
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE0 RGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGLPEDDLVLPDDVVQYIKAHASGALDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGLPEDDLVLPDDVVQYIKAHASGALDE
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE0 GTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADSNVGPSAPMLGGCQLGFGAPSSLNKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADSNVGPSAPMLGGCQLGFGAPSSLNKN
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE0 NMPVQWNEVSSGTVDSLASQVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGLQASPGGLDS
:::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
XP_006 NMPVQWNEVSSGTVDALASQVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGLQASPGGLDS
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE0 TQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCPGMTTTMSPHACYGQVHPQLSPSTIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCPGMTTTMSPHACYGQVHPQLSPSTIS
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE0 GALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTMGNRHRELGVPNSALAGVPPPHPVQS
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
XP_006 GALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTMGNRHRELGVPDSALAGVPPPHPVQS
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KE0 YPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPT
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
pF1KE0 GRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAP
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
pF1KE0 DHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTV
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
pF1KE0 DSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGI
1490 1500 1510 1520 1530 1540
1570 1580
pF1KE0 SNMAVGDMSSMLTSLAEESKFLNMMT
::::::::::::::::::::::::::
XP_006 SNMAVGDMSSMLTSLAEESKFLNMMT
1550 1560
>>XP_016859307 (OMIM: 165230,610829,615849) PREDICTED: z (1653 aa)
initn: 8118 init1: 8118 opt: 8139 Z-score: 3306.0 bits: 624.6 E(85289): 2.1e-177
Smith-Waterman score: 10392; 97.6% identity (98.0% similar) in 1565 aa overlap (22-1586:110-1653)
10 20 30 40 50
pF1KE0 METSASATASEKQEAKSGILEAAGFPDPGKKASPLVVAAAAAAAVAAQGVP
::: : . :.:: .::. ::
XP_016 SCSPASLGGHLMFPALQPGGPPPLLPLGSAAAG-QCPPRTAAPL---GAASLRPPRTLVP
80 90 100 110 120 130
60 70 80 90 100 110
pF1KE0 QHLLPPFHAPLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVISDISLIRLSPHPAGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHLLPPFHAPLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVISDISLIRLSPHPAGPG
140 150 160 170 180 190
120 130 140 150 160 170
pF1KE0 ESPFNAPHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQEHLKERGLFGLPAPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESPFNAPHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQEHLKERGLFGLPAPGT
200 210 220 230 240 250
180 190 200 210 220 230
pF1KE0 TPSDYYHQMTLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDVSRFSSPRVTPRLSRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSDYYHQMTLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDVSRFSSPRVTPRLSRKR
260 270 280 290 300 310
240 250 260 270 280 290
pF1KE0 ALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHPI
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE0 NPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQLSSSSNCLSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQLSSSSNCLSDT
380 390 400 410 420 430
360 370 380 390 400 410
pF1KE0 NQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVSGHGSCGCALPLSQ
:::::::::::::::::::::::::::::::::::::::::::
XP_016 NQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQ-----------------
440 450 460 470
420 430 440 450 460 470
pF1KE0 EQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFV
480 490 500 510 520 530
480 490 500 510 520 530
pF1KE0 CRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEK
540 550 560 570 580 590
540 550 560 570 580 590
pF1KE0 PYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGP
600 610 620 630 640 650
600 610 620 630 640 650
pF1KE0 DAHVTKKQRNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAHVTKKQRNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESS
660 670 680 690 700 710
660 670 680 690 700 710
pF1KE0 GLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAA
720 730 740 750 760 770
720 730 740 750 760 770
pF1KE0 PSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENF
780 790 800 810 820 830
780 790 800 810 820 830
pF1KE0 SGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFS
840 850 860 870 880 890
840 850 860 870 880 890
pF1KE0 SRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGGSGLLNLTPAQQYSLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGGSGLLNLTPAQQYSLRA
900 910 920 930 940 950
900 910 920 930 940 950
pF1KE0 KYAAATGGPPPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPLGPRRGSDGPTYGHGHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYAAATGGPPPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPLGPRRGSDGPTYGHGHA
960 970 980 990 1000 1010
960 970 980 990 1000 1010
pF1KE0 GAAPAFPHEAPGGGARRASDPVRRPDALSLPRVQRFHSTHNVNPGPLPPCADRRGLRLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAAPAFPHEAPGGGARRASDPVRRPDALSLPRVQRFHSTHNVNPGPLPPCADRRGLRLQS
1020 1030 1040 1050 1060 1070
1020 1030 1040 1050 1060 1070
pF1KE0 HPSTDGGLARGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGLPEDDLVLPDDVVQYIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPSTDGGLARGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGLPEDDLVLPDDVVQYIK
1080 1090 1100 1110 1120 1130
1080 1090 1100 1110 1120 1130
pF1KE0 AHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADSNVGPSAPMLGGCQLGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADSNVGPSAPMLGGCQLGF
1140 1150 1160 1170 1180 1190
1140 1150 1160 1170 1180 1190
pF1KE0 GAPSSLNKNNMPVQWNEVSSGTVDSLASQVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGL
::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
XP_016 GAPSSLNKNNMPVQWNEVSSGTVDALASQVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGL
1200 1210 1220 1230 1240 1250
1200 1210 1220 1230 1240 1250
pF1KE0 QASPGGLDSTQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCPGMTTTMSPHACYGQVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QASPGGLDSTQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCPGMTTTMSPHACYGQVH
1260 1270 1280 1290 1300 1310
1260 1270 1280 1290 1300 1310
pF1KE0 PQLSPSTISGALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTMGNRHRELGVPNSALAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
XP_016 PQLSPSTISGALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTMGNRHRELGVPDSALAG
1320 1330 1340 1350 1360 1370
1320 1330 1340 1350 1360 1370
pF1KE0 VPPPHPVQSYPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPPPHPVQSYPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQP
1380 1390 1400 1410 1420 1430
1380 1390 1400 1410 1420 1430
pF1KE0 RPPLEPSPTGRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPPLEPSPTGRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQP
1440 1450 1460 1470 1480 1490
1440 1450 1460 1470 1480 1490
pF1KE0 PPQDAGGAPDHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQPQACQDSIQPQPLPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPQDAGGAPDHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQPQACQDSIQPQPLPSP
1500 1510 1520 1530 1540 1550
1500 1510 1520 1530 1540 1550
pF1KE0 GVNQVSSTVDSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVNQVSSTVDSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSL
1560 1570 1580 1590 1600 1610
1560 1570 1580
pF1KE0 TLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT
:::::::::::::::::::::::::::::::::::
XP_016 TLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT
1620 1630 1640 1650
>>XP_011513576 (OMIM: 146510,165240,174200,174700,175700 (1521 aa)
initn: 3350 init1: 1220 opt: 2500 Z-score: 1030.5 bits: 203.5 E(85289): 1.2e-50
Smith-Waterman score: 4182; 48.3% identity (69.0% similar) in 1583 aa overlap (51-1585:65-1520)
30 40 50 60 70 80
pF1KE0 EAAGFPDPGKKASPLVVAAAAAAAVAAQGVPQHLLPPFHAPLPIDMRHQEGRYHYEPHSV
: ::.: :: :.::: ::.::::::.: .
XP_011 LPHVAEPSVPYRGTVFAMDPRNGYMEPHYHPPHLFPAFHPPVPIDARHHEGRYHYDPSPI
40 50 60 70 80 90
90 100 110 120 130
pF1KE0 HGVHGPPALSGSPVISDISLIRLSPH--PAGPGESPFNAPHPYVNPHMEHYLRSVHSSPT
.: :::.::. :. .::.::: :.. .::::. ::::.::.:. :.::.::::.
XP_011 PPLHMTSALSSSPTYPDLPFIRISPHRNPTAASESPFSPPHPYINPYMD-YIRSLHSSPS
100 110 120 130 140 150
140 150 160 170 180 190
pF1KE0 LSMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQMTLVAGHPAPYGDLLMQSG
::::::.:::::.:. : :..:..:::::.:..:. .::.:.. ...
XP_011 LSMISATRGLSPTDA-------------PHAGVSPAEYYHQMALLTGQRSPYADIIPSAA
160 170 180 190 200
200 210 220 230 240 250
pF1KE0 GAASAPHLHDYLNPVDVSRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVA
:... .::. .: .::::::.. : ::::.:::::::: :.::: ::::::::::.
XP_011 TAGTGAIHMEYLHAMDSTRFSSPRLSARPSRKRTLSISPLSDHSFDLQTMIRTSPNSLVT
210 220 230 240 250 260
260 270 280 290 300 310
pF1KE0 YINNSRSSSAASGSYGHLSAGALSPAFTFPHPINPVA---YQQILSQQRGLGSAFGHTPP
.:::::::.::::::::::.:.:::..: . ::. .:::::.:..:::::::.::
XP_011 ILNNSRSSSSASGSYGHLSASAISPALSFTYSSAPVSLHMHQQILSRQQSLGSAFGHSPP
270 280 290 300 310 320
320 330 340 350 360 370
pF1KE0 LIQPSPTFLAQQPMALTSINATPTQLSSSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRS
::.:.::: .:.:. .:.:.::. :...::: .:::::::: .:. .:::
XP_011 LIHPAPTFPTQRPIPGIPTVLNPVQVSSGP---SESSQNKPTSESAVSSTGDPMH-NKRS
330 340 350 360 370
380 390 400 410 420 430
pF1KE0 KVKTEPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIY
:.: :. : :: : .:: . : . .::. :.:. ::: :: ::
XP_011 KIK--PDEDLP-SPGA--RGQQE-----------QPEGTTLVKEEGDKDESKQEPEV-IY
380 390 400 410
440 450 460 470 480 490
pF1KE0 ETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMR
::::::: :..:.::::::::::::.::::::::::::: :.:::::::::::::::::
XP_011 ETNCHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMR
420 430 440 450 460 470
500 510 520 530 540 550
pF1KE0 RHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQN
:::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQN
480 490 500 510 520 530
560 570 580 590 600 610
pF1KE0 RTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGD
:::::::::.::::::::::::::::::::::::::.::::::::.:.: : : ...:.
XP_011 RTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGS
540 550 560 570 580 590
620 630 640 650 660
pF1KE0 SEAGTEPGGP------ESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPS
. :: : :. . :.:.. :.::.:...:.:. : :::.::::::. :
XP_011 HSQSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQS
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE0 PLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAAPSAGGLQLRKHMTTMHRF
:... : ::.:.: : ::.:::.:.:.:: :.. .: .: .:: :.. . . .
XP_011 PISNYSN--SGLELPLTDGGSIGDLSAIDETPI-MDSTISTATTALALQARRNPAGTKWM
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE0 EQLKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPAGLLPNPRLS
:..: :.::... .: . . :: :.:. .: . :: : :::. : :
XP_011 EHVKLERLKQVNGMFPRLNPILPPKAPAVSPLIGNGTQSNNTCSLGG--PMTLLPG-R-S
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE0 ELSASEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNA
.::. .::::..:. :::::.::.:::: ::::::::: :::::::::: . :::.:.
XP_011 DLSGVDVTMLNMLN-RRDSSASTISSAYLSSRRSSGISPCFSSRRSSEASQ-AEGRPQNV
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE0 SSADSYDPISTDASRRSSEASQCSGGSGLLNLTPAQQYSLRAKYAAATGGPPPTPLPGLE
: :::::::::::::::::::: .: .::.::::::: :.::::::::::::::::..:
XP_011 SVADSYDPISTDASRRSSEASQSDGLPSLLSLTPAQQYRLKAKYAAATGGPPPTPLPNME
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE0 RMSLRTRLALL-DA--PERTLPAGCPRPL-GPRRGSDGPTYGHGHAGAAPAFPHEAPGGG
::::.:::::: :: : .:: :. .::: ::: ..:.:. : :.::: :
XP_011 RMSLKTRLALLGDALEPGVALP-----PVHAPRRCSDGGAHGYGRRHLQP---HDAPGHG
900 910 920 930 940
970 980 990 1000 1010 1020
pF1KE0 ARRASDPVRR-PDALSLPRVQRFHSTHNVNPGPLPPCADRRGLRLQSHPSTDGGLARGAY
.:::::::: ..:.:::: :: : . :: . :..:.: ::.. .:: .:. .
XP_011 VRRASDPVRTGSEGLALPRVPRFSSLSSCNPPAMATSAEKRSLVLQNYTRPEGGQSRNFH
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE0 S-PRPPSISENVAMEAVAAGVDGAGPEADLGLPEDDLVLPDDVVQYIKAHASGALDEGTG
: : ::::.:::..:... .:: .: ..:. ::::::::.... .. :
XP_011 SSPCPPSITENVTLESLTM-------DADANLNDEDF-LPDDVVQYLNSQNQA----GYE
1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KE0 QVYPTESTGFSDNPRLP-SPGLHGQRRMVAADSNVGPSAPML-GGCQLGFGAPSSLNKNN
: .: ... :. ..: .:: . ::..: . : : : .:..
XP_011 QHFP---SALPDDSKVPHGPGDFDAPGL--PDSHAGQQFHALEQPCPEG-------SKTD
1060 1070 1080 1090
1150 1160 1170 1180 1190
pF1KE0 MPVQWNEVSSGTVDSLASQVK--P-PPFPQ-------GNLAVVQQKPAF-GQYPGYSPQG
.:.::::::::..: .:..: : : :: ....: :.: : ::. :
XP_011 LPIQWNEVSSGSADLSSSKLKCGPRPAVPQTRAFGFCNGMVVHPQNPLRSGPAGGYQTLG
1100 1110 1120 1130 1140 1150
1200 1210 1220 1230 1240
pF1KE0 LQASP-GGLDSTQPHLQPRSGAPS-----QGIPRVNYMQQL-RQPVAGSQCPGMTTTMSP
...: :: . . : .: ::. . : .: . : ::::: ::
XP_011 ENSNPYGGPEHLMLHNSPGSGTSGNAFHEQPCKAPQYGNCLNRQPVA----PGALD----
1160 1170 1180 1190 1200 1210
1250 1260 1270 1280 1290 1300
pF1KE0 HACYGQVHP-QLSPSTISGALNQFPQSCSNMPAKP-GHLGHPQQTEVAPDPTTMGN-RHR
:: . .. .:. . ..:. .:. . : . : . . .:.. ::. .: :.
XP_011 GACGAGIQASKLKSTPMQGSGGQLNFGLPVAPNESAGSMVNGMQNQ---DPVGQGYLAHQ
1220 1230 1240 1250 1260
1310 1320 1330 1340 1350
pF1KE0 ELGVPNSALAGVPPPHPVQSYP-QQSHHLAASMSQEGYHQVP-SLLPARQPGFMEPQTGP
:: .: :: . : :: .. :. . .: : : ::. . :
XP_011 LLG--DSM------QHPGAGRPGQQMLGQISATSHINIYQGPESCLPGAH--------G-
1270 1280 1290 1300 1310
1360 1370 1380 1390 1400 1410
pF1KE0 MGVATAGFGLVQPRPPLEPSPTGRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEAVPK
:: .....:. : : : .: :. : . :. :.: . .
XP_011 MGSQPSSLAVVRGYQPCA-SFGGSRRQ--------AMPRDS----LALQSGQLSDTSQTC
1320 1330 1340 1350
1420 1430 1440 1450 1460 1470
pF1KE0 GAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQPQA
. : . :: : .. ..: .: . . .:: . :: .. . .
XP_011 RVNGIKMEMKGQPHPL-CSNLQNYSGQFYDQTVGFSQQD---TKAGSFSI------SDAS
1360 1370 1380 1390 1400
1480 1490 1500 1510 1520 1530
pF1KE0 CQ---DSIQPQPLPSPGVNQVSSTVDS---QLLEAPQIDFDAIMDDGDHSSLFSGALSPS
: : . . : :::.:::.::::: . ::. :::::::.::::::::.:::::::
XP_011 CLLQGTSAKNSELLSPGANQVTSTVDSLDSHDLEGVQIDFDAIIDDGDHSSLMSGALSPS
1410 1420 1430 1440 1450 1460
1540 1550 1560 1570 1580
pF1KE0 LLHSLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT
....::..:::::::: :: .:.. . .:::.:::::.::::::::::: .:
XP_011 IIQNLSHSSSRLTTPRASLPFPALSMSTTNMAIGDMSSLLTSLAEESKFLAVMQ
1470 1480 1490 1500 1510 1520
1586 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 01:53:14 2016 done: Sat Nov 5 01:53:17 2016
Total Scan time: 19.410 Total Display time: 0.910
Function used was FASTA [36.3.4 Apr, 2011]