Result of FASTA (omim) for
pF1KE0299
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0299, 5143 aa
1>>>pF1KE0299 5143 - 5143 aa - 5143 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 22.3207+/-0.000646; mu= -49.6098+/- 0.041
mean_var=1096.9992+/-226.206, 0's: 0 Z-trim(123.5): 289 B-trim: 0 in 0/60
Lambda= 0.038723
statistics sampled from 42937 (43327) to 42937 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.744), E-opt: 0.2 (0.508), width: 16
Scan time: 43.440
The best scores are: opt bits E(85289)
NP_149015 (OMIM: 604918,608027) protein piccolo is (5142) 33769 1905.1 0
NP_055325 (OMIM: 604918,608027) protein piccolo is (4935) 32373 1827.1 0
XP_016867496 (OMIM: 604918,608027) PREDICTED: prot (2561) 9206 532.7 4.8e-149
XP_016867495 (OMIM: 604918,608027) PREDICTED: prot (2838) 9206 532.8 5.2e-149
NP_003449 (OMIM: 604020) protein bassoon [Homo sap (3926) 1337 93.2 1.5e-16
XP_016860308 (OMIM: 188840,600334,603689,604145,60 (35622) 691 57.6 7.3e-05
NP_001121180 (OMIM: 208250,604283) proteoglycan 4 (1363) 596 51.6 0.00017
NP_005798 (OMIM: 208250,604283) proteoglycan 4 iso (1404) 596 51.6 0.00018
NP_001290161 (OMIM: 208250,604283) proteoglycan 4 (1361) 572 50.3 0.00044
XP_016860310 (OMIM: 188840,600334,603689,604145,60 (34087) 637 54.5 0.00057
XP_016860309 (OMIM: 188840,600334,603689,604145,60 (34088) 637 54.5 0.00057
NP_001121182 (OMIM: 208250,604283) proteoglycan 4 (1270) 554 49.3 0.00083
XP_016855492 (OMIM: 208250,604283) PREDICTED: prot (1270) 554 49.3 0.00083
NP_001121181 (OMIM: 208250,604283) proteoglycan 4 (1311) 554 49.3 0.00085
XP_016855491 (OMIM: 208250,604283) PREDICTED: prot (1311) 554 49.3 0.00085
NP_001254479 (OMIM: 188840,600334,603689,604145,60 (35991) 623 53.8 0.001
NP_061939 (OMIM: 176270,605283,615547) MAGE-like p (1249) 546 48.8 0.0011
NP_006239 (OMIM: 168810) basic salivary proline-ri ( 416) 518 47.0 0.0013
NP_940881 (OMIM: 611166) tetra-peptide repeat home ( 411) 488 45.4 0.004
XP_016869755 (OMIM: 120215,130000) PREDICTED: coll (1715) 500 46.3 0.0087
NP_001265003 (OMIM: 120215,130000) collagen alpha- (1838) 500 46.3 0.0092
NP_000084 (OMIM: 120215,130000) collagen alpha-1(V (1838) 500 46.3 0.0092
>>NP_149015 (OMIM: 604918,608027) protein piccolo isofor (5142 aa)
initn: 19311 init1: 19311 opt: 33769 Z-score: 10208.3 bits: 1905.1 E(85289): 0
Smith-Waterman score: 33769; 99.9% identity (100.0% similar) in 5143 aa overlap (1-5143:1-5142)
10 20 30 40 50 60
pF1KE0 MGNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 MGNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 ECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 ECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 TESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 TESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 EKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 EKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE0 KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE0 PQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 PQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE0 IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHE
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE0 VSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 VSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFV
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE0 DDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 DDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE0 IEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 IEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSID
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE0 EDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 EDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKY
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE0 SAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDED
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE0 SDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQR
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE0 KSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 KSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE0 PSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 PSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEE
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE0 MMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 MMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEE
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE0 NGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 NGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESH
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE0 EIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 EIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDR
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE0 MPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 MPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHE
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE0 SLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKF
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE0 EDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 EDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPK
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE0 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE0 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE0 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KE0 TLETTAVLRSNGLPITRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
NP_149 TLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KE0 TTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 TTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETY
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KE0 VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFY
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690 2700
pF1KE0 ISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 ISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPP
2650 2660 2670 2680 2690 2700
2710 2720 2730 2740 2750 2760
pF1KE0 EPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 EPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITA
2710 2720 2730 2740 2750 2760
2770 2780 2790 2800 2810 2820
pF1KE0 NEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASTSYTTGTESLVGAEHAM
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
NP_149 NEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAM
2770 2780 2790 2800 2810 2820
2830 2840 2850 2860 2870 2880
pF1KE0 TTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 TTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVT
2830 2840 2850 2860 2870 2880
2890 2900 2910 2920 2930 2940
pF1KE0 NGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKIIEDDEKPVDLTAGRRAV
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
NP_149 NGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKIIED-EKPVDLTAGRRAV
2890 2900 2910 2920 2930
2950 2960 2970 2980 2990 3000
pF1KE0 CCDVVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 CCDVVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNL
2940 2950 2960 2970 2980 2990
3010 3020 3030 3040 3050 3060
pF1KE0 AEAGHFFYKSKNAFDYSEGTDTAVDLTSGRVTTGEVMDYSSKTTGPYPETRQVISGAGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 AEAGHFFYKSKNAFDYSEGTDTAVDLTSGRVTTGEVMDYSSKTTGPYPETRQVISGAGIS
3000 3010 3020 3030 3040 3050
3070 3080 3090 3100 3110 3120
pF1KE0 TPQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVRDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 TPQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVRDLS
3060 3070 3080 3090 3100 3110
3130 3140 3150 3160 3170 3180
pF1KE0 GIHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTGIDISASLQTITMESLTAETID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 GIHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTGIDISASLQTITMESLTAETID
3120 3130 3140 3150 3160 3170
3190 3200 3210 3220 3230 3240
pF1KE0 SVPTLTTASEVFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SVPTLTTASEVFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWER
3180 3190 3200 3210 3220 3230
3250 3260 3270 3280 3290 3300
pF1KE0 QEIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 QEIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQL
3240 3250 3260 3270 3280 3290
3310 3320 3330 3340 3350 3360
pF1KE0 QQQLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 QQQLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTA
3300 3310 3320 3330 3340 3350
3370 3380 3390 3400 3410 3420
pF1KE0 SAVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SAVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKV
3360 3370 3380 3390 3400 3410
3430 3440 3450 3460 3470 3480
pF1KE0 RGQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 RGQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQ
3420 3430 3440 3450 3460 3470
3490 3500 3510 3520 3530 3540
pF1KE0 DEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 DEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSI
3480 3490 3500 3510 3520 3530
3550 3560 3570 3580 3590 3600
pF1KE0 RARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 RARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIG
3540 3550 3560 3570 3580 3590
3610 3620 3630 3640 3650 3660
pF1KE0 YSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 YSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHP
3600 3610 3620 3630 3640 3650
3670 3680 3690 3700 3710 3720
pF1KE0 DMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 DMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKK
3660 3670 3680 3690 3700 3710
3730 3740 3750 3760 3770 3780
pF1KE0 VKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 VKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAK
3720 3730 3740 3750 3760 3770
3790 3800 3810 3820 3830 3840
pF1KE0 LRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 LRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEV
3780 3790 3800 3810 3820 3830
3850 3860 3870 3880 3890 3900
pF1KE0 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA
3840 3850 3860 3870 3880 3890
3910 3920 3930 3940 3950 3960
pF1KE0 PTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 PTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVI
3900 3910 3920 3930 3940 3950
3970 3980 3990 4000 4010 4020
pF1KE0 QQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 QQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERS
3960 3970 3980 3990 4000 4010
4030 4040 4050 4060 4070 4080
pF1KE0 SMASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SMASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRL
4020 4030 4040 4050 4060 4070
4090 4100 4110 4120 4130 4140
pF1KE0 LRTTETRRSQEVTDFLAPLQSSSRLHSYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 LRTTETRRSQEVTDFLAPLQSSSRLHSYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESL
4080 4090 4100 4110 4120 4130
4150 4160 4170 4180 4190 4200
pF1KE0 DHLAGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 DHLAGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPK
4140 4150 4160 4170 4180 4190
4210 4220 4230 4240 4250 4260
pF1KE0 MSKFSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 MSKFSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSS
4200 4210 4220 4230 4240 4250
4270 4280 4290 4300 4310 4320
pF1KE0 LGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 LGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQ
4260 4270 4280 4290 4300 4310
4330 4340 4350 4360 4370 4380
pF1KE0 EAEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 EAEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAG
4320 4330 4340 4350 4360 4370
4390 4400 4410 4420 4430 4440
pF1KE0 PLPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 PLPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRR
4380 4390 4400 4410 4420 4430
4450 4460 4470 4480 4490 4500
pF1KE0 EETDWFDKPRESRLENGHGLDRKLPERLVHSRPLSQHQEQIIQMNGKTMHYIFPHARIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 EETDWFDKPRESRLENGHGLDRKLPERLVHSRPLSQHQEQIIQMNGKTMHYIFPHARIKI
4440 4450 4460 4470 4480 4490
4510 4520 4530 4540 4550 4560
pF1KE0 TRDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 TRDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWN
4500 4510 4520 4530 4540 4550
4570 4580 4590 4600 4610 4620
pF1KE0 GIPLTSKTYEEVQSIISQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKAVDKAKSPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 GIPLTSKTYEEVQSIISQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKAVDKAKSPGV
4560 4570 4580 4590 4600 4610
4630 4640 4650 4660 4670 4680
pF1KE0 DPKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 DPKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHG
4620 4630 4640 4650 4660 4670
4690 4700 4710 4720 4730 4740
pF1KE0 SSKPTDGTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SSKPTDGTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPG
4680 4690 4700 4710 4720 4730
4750 4760 4770 4780 4790 4800
pF1KE0 RGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 RGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSS
4740 4750 4760 4770 4780 4790
4810 4820 4830 4840 4850 4860
pF1KE0 NDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 NDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGI
4800 4810 4820 4830 4840 4850
4870 4880 4890 4900 4910 4920
pF1KE0 FPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 FPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAA
4860 4870 4880 4890 4900 4910
4930 4940 4950 4960 4970 4980
pF1KE0 EAAVQQLRIQPTKPPNHRPAESSVSTGSSGSSFGSGYSVDSEGSSSTAGETNLFPIPRIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 EAAVQQLRIQPTKPPNHRPAESSVSTGSSGSSFGSGYSVDSEGSSSTAGETNLFPIPRIG
4920 4930 4940 4950 4960 4970
4990 5000 5010 5020 5030 5040
pF1KE0 KMGQNGQEPVKQPGVGVGLADTEAKTQVMGEIKIALKKEMKTDGEQLIVEILQCRNITYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 KMGQNGQEPVKQPGVGVGLADTEAKTQVMGEIKIALKKEMKTDGEQLIVEILQCRNITYK
4980 4990 5000 5010 5020 5030
5050 5060 5070 5080 5090 5100
pF1KE0 FKSPDHLPDLYVKIYVMNISTQKKVIKKKTRVCRHDREPSFNETFRFSLSPAGHSLQILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 FKSPDHLPDLYVKIYVMNISTQKKVIKKKTRVCRHDREPSFNETFRFSLSPAGHSLQILL
5040 5050 5060 5070 5080 5090
5110 5120 5130 5140
pF1KE0 FSNGGKFMKKTLIGEACIWLDKVDLRKRIVNWHKLLVSPTQTH
:::::::::::::::::::::::::::::::::::::::::::
NP_149 FSNGGKFMKKTLIGEACIWLDKVDLRKRIVNWHKLLVSPTQTH
5100 5110 5120 5130 5140
>>NP_055325 (OMIM: 604918,608027) protein piccolo isofor (4935 aa)
initn: 32394 init1: 19311 opt: 32373 Z-score: 9787.1 bits: 1827.1 E(85289): 0
Smith-Waterman score: 32373; 99.9% identity (100.0% similar) in 4933 aa overlap (1-4933:1-4932)
10 20 30 40 50 60
pF1KE0 MGNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MGNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 ECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 TESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 EKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE0 KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE0 PQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE0 IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHE
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE0 VSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFV
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE0 DDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE0 IEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSID
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE0 EDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKY
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE0 SAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDED
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE0 SDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQR
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE0 KSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE0 PSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEE
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE0 MMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEE
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE0 NGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESH
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE0 EIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDR
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE0 MPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHE
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE0 SLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKF
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE0 EDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPK
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE0 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE0 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE0 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KE0 TLETTAVLRSNGLPITRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
NP_055 TLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KE0 TTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETY
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KE0 VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFY
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690 2700
pF1KE0 ISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPP
2650 2660 2670 2680 2690 2700
2710 2720 2730 2740 2750 2760
pF1KE0 EPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITA
2710 2720 2730 2740 2750 2760
2770 2780 2790 2800 2810 2820
pF1KE0 NEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASTSYTTGTESLVGAEHAM
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
NP_055 NEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAM
2770 2780 2790 2800 2810 2820
2830 2840 2850 2860 2870 2880
pF1KE0 TTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVT
2830 2840 2850 2860 2870 2880
2890 2900 2910 2920 2930 2940
pF1KE0 NGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKIIEDDEKPVDLTAGRRAV
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
NP_055 NGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKIIED-EKPVDLTAGRRAV
2890 2900 2910 2920 2930
2950 2960 2970 2980 2990 3000
pF1KE0 CCDVVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CCDVVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNL
2940 2950 2960 2970 2980 2990
3010 3020 3030 3040 3050 3060
pF1KE0 AEAGHFFYKSKNAFDYSEGTDTAVDLTSGRVTTGEVMDYSSKTTGPYPETRQVISGAGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AEAGHFFYKSKNAFDYSEGTDTAVDLTSGRVTTGEVMDYSSKTTGPYPETRQVISGAGIS
3000 3010 3020 3030 3040 3050
3070 3080 3090 3100 3110 3120
pF1KE0 TPQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVRDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TPQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVRDLS
3060 3070 3080 3090 3100 3110
3130 3140 3150 3160 3170 3180
pF1KE0 GIHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTGIDISASLQTITMESLTAETID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GIHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTGIDISASLQTITMESLTAETID
3120 3130 3140 3150 3160 3170
3190 3200 3210 3220 3230 3240
pF1KE0 SVPTLTTASEVFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVPTLTTASEVFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWER
3180 3190 3200 3210 3220 3230
3250 3260 3270 3280 3290 3300
pF1KE0 QEIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QEIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQL
3240 3250 3260 3270 3280 3290
3310 3320 3330 3340 3350 3360
pF1KE0 QQQLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QQQLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTA
3300 3310 3320 3330 3340 3350
3370 3380 3390 3400 3410 3420
pF1KE0 SAVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SAVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKV
3360 3370 3380 3390 3400 3410
3430 3440 3450 3460 3470 3480
pF1KE0 RGQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RGQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQ
3420 3430 3440 3450 3460 3470
3490 3500 3510 3520 3530 3540
pF1KE0 DEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSI
3480 3490 3500 3510 3520 3530
3550 3560 3570 3580 3590 3600
pF1KE0 RARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIG
3540 3550 3560 3570 3580 3590
3610 3620 3630 3640 3650 3660
pF1KE0 YSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHP
3600 3610 3620 3630 3640 3650
3670 3680 3690 3700 3710 3720
pF1KE0 DMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKK
3660 3670 3680 3690 3700 3710
3730 3740 3750 3760 3770 3780
pF1KE0 VKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAK
3720 3730 3740 3750 3760 3770
3790 3800 3810 3820 3830 3840
pF1KE0 LRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEV
3780 3790 3800 3810 3820 3830
3850 3860 3870 3880 3890 3900
pF1KE0 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA
3840 3850 3860 3870 3880 3890
3910 3920 3930 3940 3950 3960
pF1KE0 PTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVI
3900 3910 3920 3930 3940 3950
3970 3980 3990 4000 4010 4020
pF1KE0 QQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERS
3960 3970 3980 3990 4000 4010
4030 4040 4050 4060 4070 4080
pF1KE0 SMASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SMASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRL
4020 4030 4040 4050 4060 4070
4090 4100 4110 4120 4130 4140
pF1KE0 LRTTETRRSQEVTDFLAPLQSSSRLHSYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LRTTETRRSQEVTDFLAPLQSSSRLHSYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESL
4080 4090 4100 4110 4120 4130
4150 4160 4170 4180 4190 4200
pF1KE0 DHLAGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DHLAGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPK
4140 4150 4160 4170 4180 4190
4210 4220 4230 4240 4250 4260
pF1KE0 MSKFSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MSKFSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSS
4200 4210 4220 4230 4240 4250
4270 4280 4290 4300 4310 4320
pF1KE0 LGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQ
4260 4270 4280 4290 4300 4310
4330 4340 4350 4360 4370 4380
pF1KE0 EAEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EAEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAG
4320 4330 4340 4350 4360 4370
4390 4400 4410 4420 4430 4440
pF1KE0 PLPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PLPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRR
4380 4390 4400 4410 4420 4430
4450 4460 4470 4480 4490 4500
pF1KE0 EETDWFDKPRESRLENGHGLDRKLPERLVHSRPLSQHQEQIIQMNGKTMHYIFPHARIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EETDWFDKPRESRLENGHGLDRKLPERLVHSRPLSQHQEQIIQMNGKTMHYIFPHARIKI
4440 4450 4460 4470 4480 4490
4510 4520 4530 4540 4550 4560
pF1KE0 TRDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TRDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWN
4500 4510 4520 4530 4540 4550
4570 4580 4590 4600 4610 4620
pF1KE0 GIPLTSKTYEEVQSIISQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKAVDKAKSPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GIPLTSKTYEEVQSIISQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKAVDKAKSPGV
4560 4570 4580 4590 4600 4610
4630 4640 4650 4660 4670 4680
pF1KE0 DPKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DPKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHG
4620 4630 4640 4650 4660 4670
4690 4700 4710 4720 4730 4740
pF1KE0 SSKPTDGTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SSKPTDGTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPG
4680 4690 4700 4710 4720 4730
4750 4760 4770 4780 4790 4800
pF1KE0 RGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSS
4740 4750 4760 4770 4780 4790
4810 4820 4830 4840 4850 4860
pF1KE0 NDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGI
4800 4810 4820 4830 4840 4850
4870 4880 4890 4900 4910 4920
pF1KE0 FPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAA
4860 4870 4880 4890 4900 4910
4930 4940 4950 4960 4970 4980
pF1KE0 EAAVQQLRIQPTKPPNHRPAESSVSTGSSGSSFGSGYSVDSEGSSSTAGETNLFPIPRIG
:::::::::::.:
NP_055 EAAVQQLRIQPSKRRK
4920 4930
>>XP_016867496 (OMIM: 604918,608027) PREDICTED: protein (2561 aa)
initn: 10357 init1: 9184 opt: 9206 Z-score: 2796.9 bits: 532.7 E(85289): 4.8e-149
Smith-Waterman score: 12337; 51.8% identity (51.9% similar) in 4933 aa overlap (1-4933:1-2558)
10 20 30 40 50 60
pF1KE0 MGNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 ECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 TESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 EKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE0 KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE0 PQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL
:::::::::::::::::::
XP_016 PQPPCTAKPDQVEPGKEKT-----------------------------------------
1330
1390 1400 1410 1420 1430 1440
pF1KE0 IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHE
XP_016 ------------------------------------------------------------
1450 1460 1470 1480 1490 1500
pF1KE0 VSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFV
XP_016 ------------------------------------------------------------
1510 1520 1530 1540 1550 1560
pF1KE0 DDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI
XP_016 ------------------------------------------------------------
1570 1580 1590 1600 1610 1620
pF1KE0 IEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSID
XP_016 ------------------------------------------------------------
1630 1640 1650 1660 1670 1680
pF1KE0 EDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKY
XP_016 ------------------------------------------------------------
1690 1700 1710 1720 1730 1740
pF1KE0 SAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDED
XP_016 ------------------------------------------------------------
1750 1760 1770 1780 1790 1800
pF1KE0 SDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQR
XP_016 ------------------------------------------------------------
1810 1820 1830 1840 1850 1860
pF1KE0 KSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
XP_016 ------------------------------------------------------------
1870 1880 1890 1900 1910 1920
pF1KE0 PSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEE
XP_016 ------------------------------------------------------------
1930 1940 1950 1960 1970 1980
pF1KE0 MMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEE
XP_016 ------------------------------------------------------------
1990 2000 2010 2020 2030 2040
pF1KE0 NGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESH
XP_016 ------------------------------------------------------------
2050 2060 2070 2080 2090 2100
pF1KE0 EIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDR
XP_016 ------------------------------------------------------------
2110 2120 2130 2140 2150 2160
pF1KE0 MPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHE
XP_016 ------------------------------------------------------------
2170 2180 2190 2200 2210 2220
pF1KE0 SLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKF
XP_016 ------------------------------------------------------------
2230 2240 2250 2260 2270 2280
pF1KE0 EDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPK
XP_016 ------------------------------------------------------------
2290 2300 2310 2320 2330 2340
pF1KE0 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF
XP_016 ------------------------------------------------------------
2350 2360 2370 2380 2390 2400
pF1KE0 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD
XP_016 ------------------------------------------------------------
2410 2420 2430 2440 2450 2460
pF1KE0 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT
XP_016 ------------------------------------------------------------
2470 2480 2490 2500 2510 2520
pF1KE0 TLETTAVLRSNGLPITRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP
XP_016 ------------------------------------------------------------
2530 2540 2550 2560 2570 2580
pF1KE0 TTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETY
XP_016 ------------------------------------------------------------
2590 2600 2610 2620 2630 2640
pF1KE0 VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFY
XP_016 ------------------------------------------------------------
2650 2660 2670 2680 2690 2700
pF1KE0 ISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPP
XP_016 ------------------------------------------------------------
2710 2720 2730 2740 2750 2760
pF1KE0 EPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITA
XP_016 ------------------------------------------------------------
2770 2780 2790 2800 2810 2820
pF1KE0 NEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASTSYTTGTESLVGAEHAM
XP_016 ------------------------------------------------------------
2830 2840 2850 2860 2870 2880
pF1KE0 TTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVT
XP_016 ------------------------------------------------------------
2890 2900 2910 2920 2930 2940
pF1KE0 NGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKIIEDDEKPVDLTAGRRAV
XP_016 ------------------------------------------------------------
2950 2960 2970 2980 2990 3000
pF1KE0 CCDVVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNL
XP_016 ------------------------------------------------------------
3010 3020 3030 3040 3050 3060
pF1KE0 AEAGHFFYKSKNAFDYSEGTDTAVDLTSGRVTTGEVMDYSSKTTGPYPETRQVISGAGIS
XP_016 ------------------------------------------------------------
3070 3080 3090 3100 3110 3120
pF1KE0 TPQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVRDLS
XP_016 ------------------------------------------------------------
3130 3140 3150 3160 3170 3180
pF1KE0 GIHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTGIDISASLQTITMESLTAETID
XP_016 ------------------------------------------------------------
3190 3200 3210 3220 3230 3240
pF1KE0 SVPTLTTASEVFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWER
XP_016 ------------------------------------------------------------
3250 3260 3270 3280 3290 3300
pF1KE0 QEIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQL
XP_016 ------------------------------------------------------------
3310 3320 3330 3340 3350 3360
pF1KE0 QQQLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTA
XP_016 ------------------------------------------------------------
3370 3380 3390 3400 3410 3420
pF1KE0 SAVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKV
XP_016 ------------------------------------------------------------
3430 3440 3450 3460 3470 3480
pF1KE0 RGQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQ
XP_016 ------------------------------------------------------------
3490 3500 3510 3520 3530 3540
pF1KE0 DEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSI
XP_016 ------------------------------------------------------------
3550 3560 3570 3580 3590 3600
pF1KE0 RARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIG
XP_016 ------------------------------------------------------------
3610 3620 3630 3640 3650 3660
pF1KE0 YSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHP
XP_016 ------------------------------------------------------------
3670 3680 3690 3700 3710 3720
pF1KE0 DMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKK
:::::::::::::::
XP_016 ---------------------------------------------TKGSQTMTSSGAQKK
1340 1350
3730 3740 3750 3760 3770 3780
pF1KE0 VKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAK
1360 1370 1380 1390 1400 1410
3790 3800 3810 3820 3830 3840
pF1KE0 LRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEV
1420 1430 1440 1450 1460 1470
3850 3860 3870 3880 3890 3900
pF1KE0 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA
1480 1490 1500 1510 1520 1530
3910 3920 3930 3940 3950 3960
pF1KE0 PTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVI
1540 1550 1560 1570 1580 1590
3970 3980 3990 4000 4010 4020
pF1KE0 QQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERS
1600 1610 1620 1630 1640 1650
4030 4040 4050 4060 4070 4080
pF1KE0 SMASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRL
1660 1670 1680 1690 1700 1710
4090 4100 4110 4120 4130 4140
pF1KE0 LRTTETRRSQEVTDFLAPLQSSSRLHSYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRTTETRRSQEVTDFLAPLQSSSRLHSYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESL
1720 1730 1740 1750 1760 1770
4150 4160 4170 4180 4190 4200
pF1KE0 DHLAGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHLAGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPK
1780 1790 1800 1810 1820 1830
4210 4220 4230 4240 4250 4260
pF1KE0 MSKFSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSKFSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSS
1840 1850 1860 1870 1880 1890
4270 4280 4290 4300 4310 4320
pF1KE0 LGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQ
1900 1910 1920 1930 1940 1950
4330 4340 4350 4360 4370 4380
pF1KE0 EAEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAG
1960 1970 1980 1990 2000 2010
4390 4400 4410 4420 4430 4440
pF1KE0 PLPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRR
2020 2030 2040 2050 2060 2070
4450 4460 4470 4480 4490 4500
pF1KE0 EETDWFDKPRESRLENGHGLDRKLPERLVHSRPLSQHQEQIIQMNGKTMHYIFPHARIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EETDWFDKPRESRLENGHGLDRKLPERLVHSRPLSQHQEQIIQMNGKTMHYIFPHARIKI
2080 2090 2100 2110 2120 2130
4510 4520 4530 4540 4550 4560
pF1KE0 TRDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWN
2140 2150 2160 2170 2180 2190
4570 4580 4590 4600 4610 4620
pF1KE0 GIPLTSKTYEEVQSIISQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKAVDKAKSPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIPLTSKTYEEVQSIISQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKAVDKAKSPGV
2200 2210 2220 2230 2240 2250
4630 4640 4650 4660 4670 4680
pF1KE0 DPKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHG
2260 2270 2280 2290 2300 2310
4690 4700 4710 4720 4730 4740
pF1KE0 SSKPTDGTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSKPTDGTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPG
2320 2330 2340 2350 2360 2370
4750 4760 4770 4780 4790 4800
pF1KE0 RGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSS
:: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RG---------AEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSS
2380 2390 2400 2410 2420
4810 4820 4830 4840 4850 4860
pF1KE0 NDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGI
2430 2440 2450 2460 2470 2480
4870 4880 4890 4900 4910 4920
pF1KE0 FPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAA
2490 2500 2510 2520 2530 2540
4930 4940 4950 4960 4970 4980
pF1KE0 EAAVQQLRIQPTKPPNHRPAESSVSTGSSGSSFGSGYSVDSEGSSSTAGETNLFPIPRIG
:::::::::::.:
XP_016 EAAVQQLRIQPSKRRK
2550 2560
>>XP_016867495 (OMIM: 604918,608027) PREDICTED: protein (2838 aa)
initn: 10570 init1: 9184 opt: 9206 Z-score: 2796.2 bits: 532.8 E(85289): 5.2e-149
Smith-Waterman score: 13682; 53.4% identity (53.4% similar) in 5204 aa overlap (1-5143:1-2838)
10 20 30 40 50 60
pF1KE0 MGNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 ECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 TESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 EKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE0 KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE0 PQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL
:::::::::::::::::::
XP_016 PQPPCTAKPDQVEPGKEKT-----------------------------------------
1330
1390 1400 1410 1420 1430 1440
pF1KE0 IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHE
XP_016 ------------------------------------------------------------
1450 1460 1470 1480 1490 1500
pF1KE0 VSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFV
XP_016 ------------------------------------------------------------
1510 1520 1530 1540 1550 1560
pF1KE0 DDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI
XP_016 ------------------------------------------------------------
1570 1580 1590 1600 1610 1620
pF1KE0 IEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSID
XP_016 ------------------------------------------------------------
1630 1640 1650 1660 1670 1680
pF1KE0 EDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKY
XP_016 ------------------------------------------------------------
1690 1700 1710 1720 1730 1740
pF1KE0 SAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDED
XP_016 ------------------------------------------------------------
1750 1760 1770 1780 1790 1800
pF1KE0 SDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQR
XP_016 ------------------------------------------------------------
1810 1820 1830 1840 1850 1860
pF1KE0 KSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
XP_016 ------------------------------------------------------------
1870 1880 1890 1900 1910 1920
pF1KE0 PSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEE
XP_016 ------------------------------------------------------------
1930 1940 1950 1960 1970 1980
pF1KE0 MMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEE
XP_016 ------------------------------------------------------------
1990 2000 2010 2020 2030 2040
pF1KE0 NGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESH
XP_016 ------------------------------------------------------------
2050 2060 2070 2080 2090 2100
pF1KE0 EIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDR
XP_016 ------------------------------------------------------------
2110 2120 2130 2140 2150 2160
pF1KE0 MPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHE
XP_016 ------------------------------------------------------------
2170 2180 2190 2200 2210 2220
pF1KE0 SLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKF
XP_016 ------------------------------------------------------------
2230 2240 2250 2260 2270 2280
pF1KE0 EDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPK
XP_016 ------------------------------------------------------------
2290 2300 2310 2320 2330 2340
pF1KE0 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF
XP_016 ------------------------------------------------------------
2350 2360 2370 2380 2390 2400
pF1KE0 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD
XP_016 ------------------------------------------------------------
2410 2420 2430 2440 2450 2460
pF1KE0 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT
XP_016 ------------------------------------------------------------
2470 2480 2490 2500 2510 2520
pF1KE0 TLETTAVLRSNGLPITRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP
XP_016 ------------------------------------------------------------
2530 2540 2550 2560 2570 2580
pF1KE0 TTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETY
XP_016 ------------------------------------------------------------
2590 2600 2610 2620 2630 2640
pF1KE0 VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFY
XP_016 ------------------------------------------------------------
2650 2660 2670 2680 2690 2700
pF1KE0 ISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPP
XP_016 ------------------------------------------------------------
2710 2720 2730 2740 2750 2760
pF1KE0 EPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITA
XP_016 ------------------------------------------------------------
2770 2780 2790 2800 2810 2820
pF1KE0 NEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASTSYTTGTESLVGAEHAM
XP_016 ------------------------------------------------------------
2830 2840 2850 2860 2870 2880
pF1KE0 TTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVT
XP_016 ------------------------------------------------------------
2890 2900 2910 2920 2930 2940
pF1KE0 NGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKIIEDDEKPVDLTAGRRAV
XP_016 ------------------------------------------------------------
2950 2960 2970 2980 2990 3000
pF1KE0 CCDVVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNL
XP_016 ------------------------------------------------------------
3010 3020 3030 3040 3050 3060
pF1KE0 AEAGHFFYKSKNAFDYSEGTDTAVDLTSGRVTTGEVMDYSSKTTGPYPETRQVISGAGIS
XP_016 ------------------------------------------------------------
3070 3080 3090 3100 3110 3120
pF1KE0 TPQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVRDLS
XP_016 ------------------------------------------------------------
3130 3140 3150 3160 3170 3180
pF1KE0 GIHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTGIDISASLQTITMESLTAETID
XP_016 ------------------------------------------------------------
3190 3200 3210 3220 3230 3240
pF1KE0 SVPTLTTASEVFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWER
XP_016 ------------------------------------------------------------
3250 3260 3270 3280 3290 3300
pF1KE0 QEIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQL
XP_016 ------------------------------------------------------------
3310 3320 3330 3340 3350 3360
pF1KE0 QQQLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTA
XP_016 ------------------------------------------------------------
3370 3380 3390 3400 3410 3420
pF1KE0 SAVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKV
XP_016 ------------------------------------------------------------
3430 3440 3450 3460 3470 3480
pF1KE0 RGQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQ
XP_016 ------------------------------------------------------------
3490 3500 3510 3520 3530 3540
pF1KE0 DEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSI
XP_016 ------------------------------------------------------------
3550 3560 3570 3580 3590 3600
pF1KE0 RARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIG
XP_016 ------------------------------------------------------------
3610 3620 3630 3640 3650 3660
pF1KE0 YSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHP
XP_016 ------------------------------------------------------------
3670 3680 3690 3700 3710 3720
pF1KE0 DMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKK
:::::::::::::::
XP_016 ---------------------------------------------TKGSQTMTSSGAQKK
1340 1350
3730 3740 3750 3760 3770 3780
pF1KE0 VKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAK
1360 1370 1380 1390 1400 1410
3790 3800 3810 3820 3830 3840
pF1KE0 LRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEV
1420 1430 1440 1450 1460 1470
3850 3860 3870 3880 3890 3900
pF1KE0 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA
1480 1490 1500 1510 1520 1530
3910 3920 3930 3940 3950 3960
pF1KE0 PTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVI
1540 1550 1560 1570 1580 1590
3970 3980 3990 4000 4010 4020
pF1KE0 QQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERS
1600 1610 1620 1630 1640 1650
4030 4040 4050 4060 4070 4080
pF1KE0 SMASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRL
1660 1670 1680 1690 1700 1710
4090 4100 4110 4120 4130 4140
pF1KE0 LRTTETRRSQEVTDFLAPLQSSSRLHSYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRTTETRRSQEVTDFLAPLQSSSRLHSYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESL
1720 1730 1740 1750 1760 1770
4150 4160 4170 4180 4190 4200
pF1KE0 DHLAGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHLAGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPK
1780 1790 1800 1810 1820 1830
4210 4220 4230 4240 4250 4260
pF1KE0 MSKFSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSKFSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSS
1840 1850 1860 1870 1880 1890
4270 4280 4290 4300 4310 4320
pF1KE0 LGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQ
1900 1910 1920 1930 1940 1950
4330 4340 4350 4360 4370 4380
pF1KE0 EAEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAG
1960 1970 1980 1990 2000 2010
4390 4400 4410 4420 4430 4440
pF1KE0 PLPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRR
2020 2030 2040 2050 2060 2070
4450 4460 4470 4480 4490 4500
pF1KE0 EETDWFDKPRESRLENGHGLDRKLPERLVHSRPLSQHQEQIIQMNGKTMHYIFPHARIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EETDWFDKPRESRLENGHGLDRKLPERLVHSRPLSQHQEQIIQMNGKTMHYIFPHARIKI
2080 2090 2100 2110 2120 2130
4510 4520 4530 4540 4550 4560
pF1KE0 TRDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWN
2140 2150 2160 2170 2180 2190
4570 4580 4590 4600 4610 4620
pF1KE0 GIPLTSKTYEEVQSIISQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKAVDKAKSPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIPLTSKTYEEVQSIISQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKAVDKAKSPGV
2200 2210 2220 2230 2240 2250
4630 4640 4650 4660 4670 4680
pF1KE0 DPKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHG
2260 2270 2280 2290 2300 2310
4690 4700 4710 4720 4730 4740
pF1KE0 SSKPTDGTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSKPTDGTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPG
2320 2330 2340 2350 2360 2370
4750 4760 4770 4780 4790 4800
pF1KE0 RGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSS
2380 2390 2400 2410 2420 2430
4810 4820 4830 4840 4850 4860
pF1KE0 NDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGI
2440 2450 2460 2470 2480 2490
4870 4880 4890 4900 4910 4920
pF1KE0 FPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAA
2500 2510 2520 2530 2540 2550
4930
pF1KE0 EAAVQQLRIQPT------------------------------------------------
::::::::::::
XP_016 EAAVQQLRIQPTAHKSGQSNHARKQHRHSIAGVLPIQRTQSDNLPPPANGNQDQSQLALR
2560 2570 2580 2590 2600 2610
4940 4950 4960 4970
pF1KE0 -------------KPPNHRPAESSVSTGSSGSSFGSGYSVDSEGSSSTAGETNLFPIPRI
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVMSDGPVKPEGAKPPNHRPAESSVSTGSSGSSFGSGYSVDSEGSSSTAGETNLFPIPRI
2620 2630 2640 2650 2660 2670
4980 4990 5000 5010 5020 5030
pF1KE0 GKMGQNGQEPVKQPGVGVGLADTEAKTQVMGEIKIALKKEMKTDGEQLIVEILQCRNITY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKMGQNGQEPVKQPGVGVGLADTEAKTQVMGEIKIALKKEMKTDGEQLIVEILQCRNITY
2680 2690 2700 2710 2720 2730
5040 5050 5060 5070 5080 5090
pF1KE0 KFKSPDHLPDLYVKIYVMNISTQKKVIKKKTRVCRHDREPSFNETFRFSLSPAGHSLQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFKSPDHLPDLYVKIYVMNISTQKKVIKKKTRVCRHDREPSFNETFRFSLSPAGHSLQIL
2740 2750 2760 2770 2780 2790
5100 5110 5120 5130 5140
pF1KE0 LFSNGGKFMKKTLIGEACIWLDKVDLRKRIVNWHKLLVSPTQTH
::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSNGGKFMKKTLIGEACIWLDKVDLRKRIVNWHKLLVSPTQTH
2800 2810 2820 2830
>>NP_003449 (OMIM: 604020) protein bassoon [Homo sapiens (3926 aa)
initn: 2915 init1: 670 opt: 1337 Z-score: 418.2 bits: 93.2 E(85289): 1.5e-16
Smith-Waterman score: 4929; 31.2% identity (54.0% similar) in 4478 aa overlap (445-4697:12-3865)
420 430 440 450 460 470
pF1KE0 VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP
: : .: :::: . : ::::
NP_003 MGNEVSLEGGAGDGPLPPGGAGPGPGPGPGPGAGKPPSAPA
10 20 30 40
480 490 500 510 520
pF1KE0 GPAKPPPQQPG--PAKPPPQQPGSAKPPSQQPGST--KPPPQQP-G---PAKPSPQQPGS
: .. : . : :: :: . :. :::: . :..: : :.:.:.: ..
NP_003 GGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASA
50 60 70 80 90 100
530 540 550 560 570 580
pF1KE0 TKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ--GL
: : ..: .. :: :. . .. . : :.. . . . :.:::. . :.. ..
NP_003 TTPGHESPRETR--AQGPAGQEADGPRRTLQVDSR-TQRSGRSPSVSPDRGSTPTSPYSV
110 120 130 140 150
590 600 610 620 630
pF1KE0 PK-------TICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLC
:. :.::.:.:..: .: . ::::::.:.. ::. ::::::::::.::::::
NP_003 PQIAPLPSSTLCPICKTSDLT-STPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLC
160 170 180 190 200 210
640 650 660 670 680 690
pF1KE0 LNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKA
:::::.:::: :.. ::: .:. : : :: :: :
NP_003 LNCQMQRALGMDMT-----------TAP--------RSKSQQQLHSPA--------LSPA
220 230 240 250
700 710 720 730 740 750
pF1KE0 PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP
: :::: :.:: .:... : :
NP_003 HSP-------------------AKQP-----LGKP----------DQERS----RGPGGP
260 270
760 770 780 790 800 810
pF1KE0 KMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD
. :.:. ::: .:. .
NP_003 Q--------------------PGSR---QAE----------TARAT--------------
280
820 830 840 850 860 870
pF1KE0 SKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPT
: :::. : :. . ..::.: :.: .:.
NP_003 --------------SVPGPA------------QAAAPPEVG--RVSPQP---PQPT-KPS
290 300 310
880 890 900 910 920 930
pF1KE0 PPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGAS
::: ::.. :. . . : .::. .. : :: .::::::.:::
NP_003 TAEPRPPAGEA-PAKSATAVPA--------GLGA------TEQT--QEGLTGKLFGLGAS
320 330 340 350
940 950 960 970 980 990
pF1KE0 IFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPS-QPPTSQGPPKSTGQAP-PAPAKSIP
...:::.:.:. :: .:. : :: : .: . .... :: :..: :.::
NP_003 LLTQASTLMSV--QPEADTQGQP-APSKGTPKIVFNDASKEAGPKPLGSGPGPGPA----
360 370 380 390 400
1000 1010 1020 1030 1040 1050
pF1KE0 VKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKS-PK
:.: : :: :...: . . : . : :: : : . :. ::
NP_003 -------PGA-KTEPGARMGPG-SGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPK
410 420 430 440 450 460
1060 1070 1080 1090 1100 1110
pF1KE0 PESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRA
.. ::::..:::.:::.: :.:::: :. ::::::::::::::.: :::::::::.:
NP_003 ERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRL
470 480 490 500 510 520
1120 1130 1140 1150 1160 1170
pF1KE0 ISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILE
. :.::. : :.: .:.:
NP_003 LEGSLGE--------------PTPLPPPTSQQ----------------------------
530
1180 1190 1200 1210 1220 1230
pF1KE0 KVKETLSMEKIPPMVTTDQKQEESKLEKDKASAL-QEKKPLPEEKKLIPEEEKIRSEEKK
::. . . . : :.. ..: : . ::: . .
NP_003 -----------PPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKAS--------------
540 550 560 570
1240 1250 1260 1270 1280 1290
pF1KE0 PLLEEKKPTPEDKKLLPEAKT-SAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGK-QP
:: . .: : .: :.:: : : .: .:..::: : .
NP_003 PLSTKASPLP--SKASPQAKPLRASEPSK-------------------TPSSVQEKKTRV
580 590 600 610
1300 1310 1320 1330 1340
pF1KE0 QTKMEGLPSGTPQSLPKEDDKTTKTI--KEQPQPPCT-AKPDQVEPGKEKTEKEDDKSDT
:: : .:. :.. : .:. . .: : . : :. . : : :: .
NP_003 PTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGG----EAEDLVGKP
620 630 640 650 660
1350 1360 1370 1380 1390 1400
pF1KE0 SSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESS-PSSPS
:.. .:::.:::::::::::::: .:: ... . ... :: . . : :::
NP_003 YSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQL------DSAGVTGPHPPSPS
670 680 690 700 710 720
1410 1420 1430 1440 1450 1460
pF1KE0 DLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEE
.. :. :.. .:.::. :: ::. ..: : ..... .::: : : :.::
NP_003 EIHKVGSSMRPLLQAQG--LAP--SER-SKPLS-SGTGEEQKQRPHSLSITPEAFDSDEE
730 740 750 760 770
1470 1480 1490 1500 1510 1520
pF1KE0 IKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQR
... :: .:. . . ..... .: ::. .. . .: ::.:::. ::.: .
NP_003 LEDILEEDEDSAEWRRR------REQQDTAESSDDFGSQLR-HDYVEDSSEGGLSPLPPQ
780 790 800 810 820
1530 1540 1550 1560 1570 1580
pF1KE0 KRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISS
. .. .:: ::.:.::.::::.:: . ::: .. .
NP_003 P--PARAAELTDE-------------DFMRRQILEMSAEED-NLEEDDTATSGRGLAKHG
830 840 850 860 870
1590 1600 1610 1620 1630 1640
pF1KE0 STESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRE
. .. . . . . . .: .::: ....:. .: . : :: : : :.
NP_003 TQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGS-----AEATDGSGTLQ---
880 890 900 910 920
1650 1660 1670 1680 1690 1700
pF1KE0 TKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDS
:::::::::::::: . . . .: .:.:::::::::: :
NP_003 --------------GGLRRFKTIELNSTGSYGHELDLGQGPDP-SLDREPELEMESLTGS
930 940 950 960 970
1710 1720 1730 1740 1750 1760
pF1KE0 PEDRSRGEGSSSLHAS--SFTPGTSPTSVSSLDEDSDSSPSHKKG--ESKQQRKARHRPH
:::::::: ::.: :: :.: ::::::.:::.::::::::... :.::::::::: :
NP_003 PEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSH
980 990 1000 1010 1020 1030
1770 1780 1790 1800 1810 1820
pF1KE0 GPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERP
:::::::::::::::::::::::.::::.::.:::. .:...:...::.::::::::::
NP_003 GPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERS
1040 1050 1060 1070 1080 1090
1830 1840 1850 1860 1870 1880
pF1KE0 KTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPS--IESDPEGFEISPEKIIEVQ
::::::::::::::::::::::::::::::::::::::: ..:. :... .: .. .
NP_003 KTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSG
1100 1110 1120 1130 1140 1150
1890 1900 1910 1920 1930
pF1KE0 KVYKLPTAVSLYSPTDEQSIMQKEGSQ-KALKSAEEMYEEMMHKTH--KYKAFPAANERD
. :.::: .::::::. : . :. . :::::: :::::.:.. . . ::. :
NP_003 SEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARG
1160 1170 1180 1190 1200 1210
1940 1950 1960 1970 1980 1990
pF1KE0 EVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEENGFMQQKGRE-QKIRLSE
: .:: . ..: :. ..: .: : : . : :.
NP_003 ------P-HGGPS-QPTGPRGLGSFEYQDTTD--------REYGQAAQPAAEGTPASLGA
1220 1230 1240 1250
2000 2010 2020 2030 2040 2050
pF1KE0 QIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESHEIVDLGTMVTSTEEERK
.::. .: . .:.: ... : .. . :... .:..
NP_003 AVYEEILQ-------------TSQSIVRMRQASSRDLAFAEDKK------------KEKQ
1260 1270 1280
2060 2070 2080 2090 2100 2110
pF1KE0 LLDADAAYEELMKRQQMQLTPGSSPTQ--APIGEDMTESTMDFDRMPDASLTSSVLSGAS
.:.:..:: . ::.. ::::.:::: ::. : ..
NP_003 FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPV------------------------SFST
1290 1300 1310 1320
2120 2130 2140 2150 2160 2170
pF1KE0 LTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATS
:.: ::. ::::..::::. .: :. . .: . : :. .
NP_003 PTSSDSSGGRVIPDVRVTQHFA-------------KETQDPLKLHSSPASPSSASKEI-G
1330 1340 1350 1360 1370
2180 2190 2200 2210 2220 2230
pF1KE0 VPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGS
.: :. :. : ....: .. : : :.. . : : ::... :
NP_003 MPFSQGPG-TPATTAVAPCPAGLP--------RGYMTPASPAGS-ERSPSPSSTAHSYGH
1380 1390 1400 1410 1420
2240 2250 2260 2270 2280 2290
pF1KE0 IIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLI
. : . : :.: :.: . . . ...: :. .:.: . .:.. .
NP_003 SPTTANYGSQTEDLPQAPSGLAAAGRAA-REKPLSASDGEGGTPQPSRAYSYFASSSPPL
1430 1440 1450 1460 1470 1480
2300 2310 2320 2330 2340 2350
pF1KE0 SEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQ
: ..: .. :. . : :. . .: : . . . :.. :: :
NP_003 SPSSPSESPTFSPGK-------MGPRATAEF-STQTPSPAPASDMPRSPGAPTPSPMVAQ
1490 1500 1510 1520 1530
2360 2370 2380 2390 2400 2410
pF1KE0 -LSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPP
.: . : . .. ... : ...: :. . . .: . : : :
NP_003 GTQTPHRPSTPRLVWQESSQEAPFMVITLAS-DASSQTRMVHASASTSPLCSPTETQPTT
1540 1550 1560 1570 1580 1590
2420 2430 2440 2450 2460 2470
pF1KE0 PPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLP
:: :: : : .:. : . : :. .: ..: ....
NP_003 HGYSQTTPPSVSQLPPEPPGPPGFPR------VPSAGA----DGPLALYGWGALPAENIS
1600 1610 1620 1630 1640
2480 2490 2500 2510 2520 2530
pF1KE0 ITRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPT
. :: ::.:. : : ::. : .: .. .: :.. ::: :
NP_003 LCRI------------SSVPG----TSRVEPG--PRTPGTAVVDLRTAV-KPTPIILTDQ
1650 1660 1670 1680
2540 2550 2560 2570 2580 2590
pF1KE0 GLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTD
:..::: : . : : :.: ...: . .::.: .. :
NP_003 GMDLTSLA----VEARKYGLA-----LDPIPGRQSTAVQP------LVINLNAQEHTFLA
1690 1700 1710 1720
2600 2610 2620 2630 2640
pF1KE0 SSASQAIT---SWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQT--FS
.... .:: : ... .. .: .: : . . :. :. . :.:: .
NP_003 TATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYR
1730 1740 1750 1760 1770 1780
2650 2660 2670 2680 2690 2700
pF1KE0 ATPVTAPSSFQAA----PTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLAL
. : : . : :..:. . .: :... :: :.::. . ::: :
NP_003 SGPRGRPREAKFARYNLPNQVAPLARRDVLITQMG----TAQSIGLKPGPV---PEPGA-
1790 1800 1810 1820 1830
2710 2720 2730 2740 2750 2760
pF1KE0 DNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANEVYG
.:. ..:. ...: .. : .... .: . . .: :
NP_003 ------EPHRATPAELRS-------HALPGAR-KPHTVVVQMGEGTAGTVTTLLPEEPAG
1840 1850 1860 1870 1880
2770 2780 2790 2800 2810 2820
pF1KE0 K-QISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTAS--TSYTTGTESLVGAEHAMTT
......: . . ..: . ... .::.. . .. .:.. : .
NP_003 ALDLTGMRPE--SQLACCDMVYKLPFGS------SCTGTFHPAPSVPEKSMADAAPPGQS
1890 1900 1910 1920 1930
2830 2840 2850 2860 2870
pF1KE0 PLQLTTSKHAEPP----YRIPSDQVFPIAREEA-PINLSLGTPAHAVTLAITKPVTVPPV
. . ::: :: . : : .:: : : :.. . . ... .
NP_003 SSPFYGPRDPEPPEPPTYRA-QGVVGPGPHEEQRPY--PQGLPGRLYSS--MSDTNLAEA
1940 1950 1960 1970 1980 1990
2880 2890 2900 2910 2920 2930
pF1KE0 GVT-NGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDEST--SSVMTKIIEDDEKPVDLT
:.. .. . . :: ..:::. : .. : .... . : ..:.::
NP_003 GLNYHAQRIGQLFQGPGRDSAMDLSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLL
2000 2010 2020 2030 2040 2050
2940 2950 2960 2970
pF1KE0 AG----RRAVCCDVVYK----------LPFGRSCTAQQPATTLPE-DRFGYRDDHYQYDR
: :: . .:. . : .. :: ::: : .:. . ..:.
NP_003 AHPLPMRRYSSVSNIYSDHRYGPRGDAVGFQEASLAQYSATTAREISRMCAALN--SMDQ
2060 2070 2080 2090 2100 2110
2980 2990 3000 3010 3020 3030
pF1KE0 SGPYGYRGIGGMKPSMSDTNLAEAGHFFYKSKNAFDYSEGTDTAVDLTSGRVTTGEVMDY
: : .: :: :.. . . . : . .. : . :. . :.. .:
NP_003 YG--GRHGSGGGGPDLVQYQ-PQHGPGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQY
2120 2130 2140 2150 2160
3040 3050 3060 3070 3080 3090
pF1KE0 SSKTTGPYPETRQVISGAGISTPQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTP
:: .: : .. : . : ...:...:..::.. ::
NP_003 -----GP-------AAGQGTAVRQ-----LLPST-------ATVRAADGMIYSTINTPIA
2170 2180 2190 2200
3100 3110 3120 3130 3140
pF1KE0 STFAITTQPGSIFSTTVRD------LSGIHTADAVTSL-------------PAMHHSQPM
.:. :::::.:.. :: :: :: .::: :. . :
NP_003 ATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPA
2210 2220 2230 2240 2250 2260
3150 3160 3170 3180 3190
pF1KE0 PRSYFITTGASETDIAV-TGIDISASLQTITMESLTAETIDSV---PTLTTASEVFPEVV
: . :.... .. : : .:. : . .. : ::. .. :..
NP_003 PSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAA
2270 2280 2290 2300 2310 2320
3200 3210 3220
pF1KE0 GDE-------------------SALLIVP--------EEDKQQQQ----LDLERELLELE
: :. : : .:..:..: :.:::: .:::
NP_003 GAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEASQEERQRKQQEQLLQLERERVELE
2330 2340 2350 2360 2370 2380
3230 3240 3250 3260 3270 3280
pF1KE0 KIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQE
:..: :. :::: :: :.:: ::.:...::..:.:::..:.:.: ::.::::::: ...:
NP_003 KLRQLRLQEELERERVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQRE
2390 2400 2410 2420 2430 2440
3290 3300 3310 3320 3330 3340
pF1KE0 TLAQQQLQLEQIQQLQQQLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAAL
::::.:::::::::::::.::::::: :: . :.. .: : : :
NP_003 QLAQQRLQLEQIQQLQQQLQQQLEEQKQRQKAPF---PAACEAPGRGPPLAAAE---LAQ
2450 2460 2470 2480 2490
3350 3360 3370 3380 3390 3400
pF1KE0 EGSQFWATEDATTTASAVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVV
.: :.: : .: .:. :.. : . . :. :..:.. :
NP_003 NG-QYWPP----LTHAAFIAMAGPEGLGQPR-------EPVLHRGLPSSASDMSL-----
2500 2510 2520 2530 2540
3410 3420 3430 3440 3450 3460
pF1KE0 KEEKQPKKRSSGAKVRGQYD---DMGENMTD-DPRSFKKIVDSGVQTDDEDATDRSYVSR
. :.: . :: : : .. : : . .: ..:.::.:::::::. .: .::
NP_003 QTEEQWEASRSGIKKRHSMPRLRDACELESGTEPCVVRRIADSSVQTDDEDGESRYLLSR
2550 2560 2570 2580 2590 2600
3470 3480 3490 3500 3510
pF1KE0 RRRTKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEA--DKTKPLSK------
:::...:.: ::::::::. ::..:.: ::..:. ...:: ... : : :.
NP_003 RRRARRSADCSVQTDDEDSAEWEQPVR-RRRSRLPRHSDSGSDSKHDATASSSSAAATVR
2610 2620 2630 2640 2650
3520 3530 3540 3550 3560
pF1KE0 -VSSIAVQTVAEISVQTEPVGTIR-TPSIR--ARVDAKVEIIKHISAPEKTYKGGSLGCQ
.::...::... :::::: : .:.:. : .: ::::...::::::: .: ::.::
NP_003 AMSSVGIQTISDCSVQTEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQ
2660 2670 2680 2690 2700 2710
3570 3580 3590 3600 3610
pF1KE0 TEADSDTQS---PQYL--SATSP--PK------------DKKRPTPLEIGYSSHLRADST
:: :...:. :: . .: :: : .::.: ::::::..:: .:
NP_003 TEPDGQAQGVAGPQLVGPTAISPYLPGIQIVTPGPLGRFEKKKPDPLEIGYQAHLPPESL
2720 2730 2740 2750 2760 2770
3620 3630 3640 3650 3660
pF1KE0 VQLAP-SPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPAS
::. .:::::.:::::.::::: . :...:. :. .:::: . : : .
NP_003 SQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTL
2780 2790 2800 2810 2820 2830
3670 3680 3690 3700 3710 3720
pF1KE0 PKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQT--MTSSGAQKKVKRTLPN
:. : .:::.::::::::::.::.. :. . :::. . .. .:::::::.
NP_003 PRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPS
2840 2850 2860 2870 2880 2890
3730 3740 3750 3760 3770 3780
pF1KE0 PPPEEIS---TGTQSTFSTMGTVSRRRICRTNTM--ARAKILQDIDRELDLVERESAKLR
::::: .: : ... .: . .:. ..:..:...::.: :::.::.:::
NP_003 PPPEEAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKASLLRELDRDLRLVEHESTKLR
2900 2910 2920 2930 2940 2950
3790 3800 3810 3820 3830 3840
pF1KE0 KKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSS
:::::::::::::::::.:::.::..:::.: :.: :. :.:..: :::.::::...
NP_003 KKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRDYPPLRGLGEHRDYLSDSELNQ
2960 2970 2980 2990 3000 3010
3850 3860 3870 3880 3890
pF1KE0 TRPTRIESQHG--IERPRTA-----PQ--TEFSQ--FIPPQTQTESQLVPPTSPYTQYQY
: . : .. : :: :. : :.: : :: : . :: :
NP_003 LRLQGCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPT------QN
3020 3030 3040 3050 3060 3070
3900 3910 3920 3930 3940 3950
pF1KE0 SSPALPTQAPTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPS
. :: :::: : : . .. : . :. :: . : :: : .
NP_003 GFPA--HQAPT-YPGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQST
3080 3090 3100 3110 3120 3130
3960 3970 3980 3990 4000
pF1KE0 -YQLPSQMMVIQQKPRQTTLY-LEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYN
. .:.. . ::::::.: :: :. .::::: . . .. . ...... ..: :.
NP_003 LFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYE
3140 3150 3160 3170 3180 3190
4010 4020 4030 4040 4050 4060
pF1KE0 SLDL----RIGLEERSSMASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALS
. . : : .:.:...:: . .:: :.......:::::.::::.:.:: .. :
NP_003 QGKVPEVPRAG--DRGSVSQSPAPTYPSDSHYTSLEQNVPRNYVMIDDISELTKDST--S
3200 3210 3220 3230 3240
4070 4080 4090 4100 4110 4120
pF1KE0 TAFSLHEKDLSKTDRLLRTTETRRSQEVTDFLAPLQSSSRLHSYVKAEEDPMEDPYELKL
:: : .. . : . : ..: . . :.. . :...::. :: :. .
NP_003 TA-----PDSQRLEPLGPGSSGRPGKEPGEP-GVLDGPTLPCCYARGEEESEEDSYDPRG
3250 3260 3270 3280 3290 3300
4130 4140 4150 4160 4170 4180
pF1KE0 LKHQIKQEFRRGTESLDHLAGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAI
: :. :: . :. .::: .:..::: . :::. . . :. .:.: :
NP_003 -----KGGHLRSMESNGRPAS-THYY-GDSDYRHGARVEKYGPGPMG-PKHPSKSLAPAA
3310 3320 3330 3340 3350
4190 4200 4210 4220 4230 4240
pF1KE0 LYQKQSKHKKSLIDPKMSKFSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITF
. .:.:::.:. .. :.::::::.:..:.: : .:: ..:: .. ::.: .::.::.
NP_003 ISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPAVSS--SLVSRGRKFQDEITY
3360 3370 3380 3390 3400 3410
4250 4260 4270 4280 4290 4300
pF1KE0 GLRKNITDQQKFMGSSLGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDL
::.::. .:::..: : :.:..: :. :...:::: ::. : :
NP_003 GLKKNVYEQQKYYGMSS-----------RDAVED--DRIYGGSSRSRA---PSAYSGEKL
3420 3430 3440 3450
4310 4320 4330 4340 4350 4360
pF1KE0 SIKRDSSSSSLRLKAQEAEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESP
: ..: :. . . .: ::.. ..: ::.:: ...:: : :. .: ::::::
NP_003 S-SHDFSGWG-KGYEREREAVE-----RLQKAGPKPSSLSMAHSRVRPPMRSQASEEESP
3460 3470 3480 3490 3500
4370 4380 4390 4400 4410 4420
pF1KE0 LSPVGQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMD
.::.:.: : :.::::: ..:: :: ::::.:.::.:... :...: :. ..:.:
NP_003 VSPLGRP----RPAGGPLPP-GGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILD
3510 3520 3530 3540 3550 3560
4430 4440 4450 4460 4470
pF1KE0 DFQHAMSDSEAYHLRREETDWFDKPRESRLE-----NGHGLDRKLPERLVHSRPLSQHQE
: . ..:::::::: .::::::::::..: . .::... . .: . : :.
NP_003 DSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARH--SYHDY
3570 3580 3590 3600 3610 3620
4480 4490 4500 4510 4520 4530
pF1KE0 QIIQMNGKTMH-YIFP--HARIKITRDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIA
. .: : : :: : : . :: : . : . :. ..: . :
NP_003 DEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEP-GRRAAKPHARDLGRHEA
3630 3640 3650 3660 3670
4540 4550 4560 4570 4580 4590
pF1KE0 KI--LPGGSAEQTGKLMEGM-QVLEWNGIPLTSKTYEEVQSIISQQSGEAEICVRLDLNM
. :... . : . :. . :.. .:..:..... :..... :.
NP_003 RPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASD--SKKGSRQAHSGPAALQS
3680 3690 3700 3710 3720 3730
4600 4610 4620 4630 4640
pF1KE0 LSDSENSQHLELHEPPKAVDKAKSPGVD--PKQLAAELQKVSLQQSPLVLS----SVVEK
.. . . .:. .. . ....::. :. :.. ... ::. : :. ....
NP_003 KAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQA
3740 3750 3760 3770 3780 3790
4650 4660 4670 4680
pF1KE0 GSHVHSGPTSAGSSSV-------PSPG-------QPGSPSVSKKKHGSS----KPTDGTK
. .: ::. ::. . :.:: ::..: ... .::. : .:
NP_003 RLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRA
3800 3810 3820 3830 3840 3850
4690 4700 4710 4720 4730 4740
pF1KE0 VVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQN
..: :
NP_003 PQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSA
3860 3870 3880 3890 3900 3910
>>XP_016860308 (OMIM: 188840,600334,603689,604145,608807 (35622 aa)
initn: 410 init1: 124 opt: 691 Z-score: 208.3 bits: 57.6 E(85289): 7.3e-05
Smith-Waterman score: 994; 24.8% identity (46.0% similar) in 1582 aa overlap (73-1530:11636-13130)
50 60 70 80 90
pF1KE0 ADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRK---QELDSSHP-PKQSGR
: :.: :. ::. .. :... .
XP_016 PIVKRRKTPSPTAPEAMKEVVPEMKIFEDVPEEPETPRMKTPEAPQEIIPAKTVPSKKRE
11610 11620 11630 11640 11650 11660
100 110 120 130 140 150
pF1KE0 PPDPGRPA--QPGLSKSRTTDT-FRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPG
::. : : . ...: . .:. . :: . : .:.: . .. ... ..:
XP_016 PPSVKVPEALQEIVPEKKTLVVPLRKPEVLPDEVPE--ALREVVPEKKVHPPQRAEVVPV
11670 11680 11690 11700 11710 11720
160 170 180 190 200 210
pF1KE0 FL----SEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPL
. .:. . :: : : .. :::.: . ...:: .:: ::.
XP_016 KVHEAPKEIIPEKKVSVVPPKKPEVPPVKVPEASKE-VIREEKVPLAPPKEPE---VPPV
11730 11740 11750 11760 11770
220 230 240 250 260
pF1KE0 Q-QQPPKPI-PKQQGPGRDPLQQDGTPKSISSQQ----PEKIKSQPPGTGKPIQGPTQTP
. .::: . :....: : . . : .. ::: :: :: ::..:
XP_016 KVPEPPKEVVPEKKAPVAPPKEPEVPPVKVPEAPKEVVPEKKVPVPPPK-KPEVPPTKVP
11780 11790 11800 11810 11820 11830
270 280 290 300 310
pF1KE0 QTDHAKLPLQR--DASRPQTKQADIVRGESVKPSLPSPSK----PPIQQPTPGKPPAQQP
.. .: .: .. .: :. .. : . :. : : :: ..: :: . :
XP_016 EVPKAAVPEKKLPEAIPPKPESPPPEVPEVLPPKEVVPEKKVPVPPAKKPEA--PPPKVP
11840 11850 11860 11870 11880 11890
320 330 340 350 360 370
pF1KE0 GHEKSQPGPAKPP-AQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ-PLGPAK--PPAQQ
: : : :. : :. : ... : : : . : .:: : . :
XP_016 EAPKEVVLEKKASVAVPKKPEAPRAKVPEAAQEVVPEKKIPKAPIKKPEAPAVTVPEVPQ
11900 11910 11920 11930 11940 11950
380 390 400 410 420 430
pF1KE0 TGSEK--PSSEQPGPKALAQP-PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK
..:: : . :.: : : . .. .. : :::. . : . . : : :
XP_016 EATEKEIPVAPPKKPEAPIVPVPEAQEVVPEKKVPKAPPTKPEAPPATVPEVPQEIVPEK
11960 11970 11980 11990 12000 12010
440 450 460 470
pF1KE0 A----PG-PTKTPVQQP-GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG------PAK--
: : :: : .: .. .. : :: : :: ..: : :
XP_016 KTLVLPKKPEVPPVTVPEAPKEVVLEKKVP---SAPPKKPEVPPVKVPEAPKEVVPEKKV
12020 12030 12040 12050 12060 12070
480 490 500 510 520 530
pF1KE0 --PPPQQPG-PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP-
:::..: : :. : .: : .. : . : :..: : : : . : .. :
XP_016 PVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEVLPPKEVVPEKKVPV
12080 12090 12100 12110 12120 12130
540 550 560 570 580 590
pF1KE0 -GSAKPSAQQPS-PAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQP--PSQGLPKTICP
. :: : :. : :. : .: . :: : . : : : : . .::. :
XP_016 PPAKKPEAPPPKVPEAPKEVVLEKKASVAVPKKPEAPRAKVPEAAQEVVPEKKIPKA--P
12140 12150 12160 12170 12180 12190
600 610 620 630 640 650
pF1KE0 LCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDL
. . . ::: . . : .. : . :..: . . :
XP_016 IKKPEAPAVTVPEVPQEAAEKEIPVAP-PKKPEAPIVPVPEAQEVVPEKKVPKAPPTKPE
12200 12210 12220 12230 12240 12250
660 670 680 690 700
pF1KE0 APVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL--SKAPE--PKKP--P
:: . :. . .: : .. :. : : :. :::. . .:.: :::: :
XP_016 APPATVPEVPQEIVPEKKTLVLPKKPEVPPVTVPE---APKEVVLEKKVPSTPPKKPEVP
12260 12270 12280 12290 12300
710 720 730 740 750
pF1KE0 PLVKQPTLHGS--PSAKAKQPPEADSLSKP-APP-KEPSVPSE---QDKAPVA-DDKPKQ
: :: : : :. :: .:: .:: : : ::. . :.: : ::..
XP_016 P-VKVPEAPKEVVPEKKVPVPPP----KKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPES
12310 12320 12330 12340 12350 12360
760 770 780 790 800
pF1KE0 PK----MVKPTTDLVSSSSATT----KPDIPSSKVQSQAEE-----KTTPPLKTDSAKPS
: : : ..: ... . ::. : :: .: :.. . :
XP_016 PPPEVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVLEKKVSVAVPKKPEAPR
12370 12380 12390 12400 12410 12420
810 820 830 840 850 860
pF1KE0 QSFPPTGEKVSPFDSKAIPR-PAS--DSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQT
. : ....: : : ::. : . .. .. : .:. ..:.. :: ::: ..
XP_016 AKVPEAAQEVVP--EKKIPKAPIKKPEAPAVTVPEVPQEA-AEKEI-PVAP---PKKPEA
12430 12440 12450 12460 12470
870 880 890 900 910
pF1KE0 KMSPKPDA------KPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQS----RRFSLNLG
. : :.: : .::. :: : :. ::: : :.... .. .
XP_016 PIVPVPEAQEVVPEKKVPKAPPTKPEAPPA---TVPEVPQEIVPEKKTLVLPKKPEVPPV
12480 12490 12500 12510 12520 12530
920 930 940 950 960
pF1KE0 SITDAPK------SQPTTPQ---ETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG
.. .::: . : .: :. :. . . . .. .: . :
XP_016 TVPEAPKEVVLEKKVPLAPPKKPEVPPVKVPEAPKEVVPEKKVPVTPPKKPEVPPVKVPE
12540 12550 12560 12570 12580 12590
970 980 990 1000 1010
pF1KE0 APMKQAPA---PSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTV
::.. .: : :: . : ..: :: . .: :: .:: :: ..: :
XP_016 APIEVVPEKKMPLAPP--KKPEVPPVKVPEAPKEVVPEKKVPSAP------PKKPEVPPV
12600 12610 12620 12630 12640
1020 1030 1040 1050 1060 1070
pF1KE0 KRTETEKKPPPIKDSKSLTAEPQKA-VLPTKLEKSPK---PESTCPL---CKTELNIGSK
: :. :. : : : .: :.: : :.:. ..:: ::. :. : :. .:
XP_016 KVPEAPKEVVPEK--KVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVP-PTK
12650 12660 12670 12680 12690 12700
1080 1090 1100 1110 1120
pF1KE0 DP--PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAP
: :. . . .. .: :.. : : . :. ... : :
XP_016 VPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVE---------EPEP
12710 12720 12730 12740 12750
1130 1140 1150 1160 1170 1180
pF1KE0 SGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMV
..: .: : . .: : : : : . :: . : ::.. .:.: .:
XP_016 AAPPQVTVP-PKKPVPEKKA--PAVVAKKPELPPVK------VPEVPKEVVPEKKVPLVV
12760 12770 12780 12790 12800
1190 1200 1210 1220 1230 1240
pF1KE0 TTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLL
. .:. . .. ::: .: .: :. :::.:::: .: .
XP_016 PKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPA-KVPEVPKKPVLEEKPAVP-----V
12810 12820 12830 12840 12850
1250 1260 1270 1280 1290 1300
pF1KE0 PEAKTSAPEE--QKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLP
:: : : : .. . . . .:: :. . : : : ..:.. ..: . .:
XP_016 PERAESPPPEVYEEPEEIAPEEEIAPEEEK----PVPVAEEEEPEVPPPAVPEEPKKIIP
12860 12870 12880 12890 12900 12910
1310 1320 1330 1340 1350 1360
pF1KE0 KEDDKTTKTIK--EQPQPPCTAKPDQVEPGKE-KTEKEDDKSDTSSSQQPKSPQGLSDTG
.: . .:: : : : : .: : :. : : : .: ... :. :. : .
XP_016 ---EKKVPVIKKPEAPPPKEPEMPKKVVPVKKVPTVK---KPETPAAKVPEVPKKLVPVK
12920 12930 12940 12950 12960
1370 1380 1390 1400 1410 1420
pF1KE0 YSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSIL-EAQ
.... .: .: . :. :. : . : : :..: : :. : .
XP_016 KEPVPVTKKPEVLPEKVPKVPEKIIPE-KEVSVPIPAEPEVPP--AEVEETPEEIIYEEK
12970 12980 12990 13000 13010 13020
1430 1440 1450 1460 1470
pF1KE0 ASTLADEKSEKKTQPHEV----SPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTF
:: .: .. .:. .::.:. . . . :: ..: : .. :. :
XP_016 ASITIGRKETPPVEEREIEKYIKPEEPEPEPQPE------EIPVKEPEPEKVIEKPKLKP
13030 13040 13050 13060 13070
1480 1490 1500 1510 1520 1530
pF1KE0 KKDSQQDIPSSKDHKEKSEFVDDITTRREPYD-SVEESSESENSPVPQRKRRTSVGSSSS
. : ..: ::: . : .. : .: :. : :: ...
XP_016 RPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPER
13080 13090 13100 13110 13120 13130
1540 1550 1560 1570 1580 1590
pF1KE0 DEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETK
XP_016 KPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRER
13140 13150 13160 13170 13180 13190
>>NP_001121180 (OMIM: 208250,604283) proteoglycan 4 isof (1363 aa)
initn: 249 init1: 151 opt: 596 Z-score: 201.6 bits: 51.6 E(85289): 0.00017
Smith-Waterman score: 832; 24.4% identity (48.1% similar) in 1116 aa overlap (88-1102:68-1117)
60 70 80 90 100 110
pF1KE0 AVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTD
. . ::... :: : ...
NP_001 ERGRECDCDAQCKKYDKCCPDYESFCAEVHNPTSPPSSKKAPPPSG-----------ASQ
40 50 60 70 80
120 130 140 150 160 170
pF1KE0 TFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFD
:..: : . :. . :. .. :::. : : .. :. ::.. :..
NP_001 TIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQES-SSSSSSSSSSSTIRKIKS--
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE0 LISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPK
: . :...: :: :: :.. : . :: : :. . : : : . :
NP_001 --SKNSAANRELQKKLKV--KDNKKNRTKKKP----TPKPPVVDEAGSGLDNGDFKVTTP
150 160 170 180 190
240 250 260 270 280
pF1KE0 SISSQQPEKIKSQPP-GTGKPIQG-PTQTPQTDHAK---LPLQRDAS---------RPQT
. :. : .:....: :.:::. :. :..: .: : ...... ::
NP_001 DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT
200 210 220 230 240 250
290 300 310 320
pF1KE0 -----------KQADIVRGESVKPSLPSP---SKPPIQQPTPGKPPAQQPGHEKSQPGPA
:... .. :.: :. .:: . : : :: .: . :
NP_001 STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK
260 270 280 290 300 310
330 340 350 360 370
pF1KE0 KP----PAQP------SGLTKPLAQQPGTVK--P--PVQP-PGTTKPPAQPLGPAKPPAQ
.: : .: :. : : : :.: : : .: : ::: :: : : .:
NP_001 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA-PTTPKEPAPT
320 330 340 350 360 370
380 390 400 410 420
pF1KE0 QTGSEKPSSEQPGPKALAQP-PGVGKTPA----QQPGPAKPPTQQVGTPK---PLAQQPG
: :.. . .: . .: : . : :: ..:.:. : ::: : ...:.
NP_001 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA
380 390 400 410 420 430
430 440 450 460 470 480
pF1KE0 LQSPAKAPGPTKTPVQQPGPGKIPAQQAG--PGKTSAQQTGPTKPPSQLPGPAKPPP---
.: : :.:: : : :: . :. :.... .:: : : .: :
NP_001 PTTP-KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT
440 450 460 470 480 490
490 500 510 520 530
pF1KE0 QQPGPAKPPPQQPGSAKPPSQQPGSTKPP----PQQPGPAKP------SPQQPGSTKPPS
..:.:. . : . : :: : .:: : :..:.:. : .:..:. : :
NP_001 KEPAPTTTK-SAPTTPKEPS--PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE
500 510 520 530 540 550
540 550 560 570 580 590
pF1KE0 QQPGSAK-PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICP
: ..: :. :. :.. . : :.. . : : ..:.. . :. :. . :
NP_001 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTPEELAP
560 570 580 590 600
600 610 620 630 640
pF1KE0 LCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN-PN-PHLTEVKEWLCLNCQMKRALGG
:: ::. . .: : :. . . : :. : : :: :
NP_001 ---TT------PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE---------PAPTT
610 620 630 640 650
650 660 670 680 690 700
pF1KE0 DLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ---DLSKAPEPK---K
:.:..:. .:::.: ... . .: :.::: : ::. .: : :
NP_001 PKEPAPTTPK---ETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTSDK
660 670 680 690 700
710 720 730 740 750 760
pF1KE0 PPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP
: : . . : .:. : :. . :. :: . . .. ::.. :: :: . :
NP_001 PAPTTPKGTAPTTPKEPAPTTPKEPA---PTTPKGTAPTTLKEPAPTTPKKPA-PKELAP
710 720 730 740 750 760
770 780 790 800 810 820
pF1KE0 TTDLVSSSSATTKPDIPSSKVQSQAEEKTTP--PLKTDSAKPSQSFPPTGEKVSPFDSKA
:: .:... :: :.. .. ::: : : ::. :: .. : ..
NP_001 TTTKGPTSTTSDKP-APTTPKET---APTTPKEPAPTTPKKPA----PTTPETPPPTTSE
770 780 790 800 810
830 840 850 860 870
pF1KE0 IPRPASDSKIIS-HPGPSSESKGQKQVDPVQKKEE--PKK-----AQTKMSPKPDAKPMP
. :.. .. . : .:. :: . ...:. : : ::. ..: . ::.
NP_001 VSTPTTTKEPTTIHKSPD-ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA
820 830 840 850 860 870
880 890 900 910 920
pF1KE0 KGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITD----APKSQPTTPQETVT
: . : : : :. .:... . ... . . . : . .: ::: . .:
NP_001 KDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT
880 890 900 910 920 930
930 940 950 960 970 980
pF1KE0 GKLFGFGASIFSQASNLISTAGQPGPHSQSGPG--APMKQAPAPSQPPTSQGPPKSTGQA
: .. .. . ... .: . :. . : : ..: .:. ...: : :.
NP_001 LKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK
940 950 960 970 980 990
990 1000 1010 1020 1030 1040
pF1KE0 PPAPAKSIP-VKKETKAPAAEKLEPKA-EQAPTVKRTE----TEKKPPPIKDSKSLTAEP
: :..: :.: .:. .:. : :: . .: : .: .:: . ..:
NP_001 KP---KTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNP
1000 1010 1020 1030 1040 1050
1050 1060 1070 1080 1090
pF1KE0 QKAVLPTKLEKSP----KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTP
.. ..: .:. : ... . : . . .. :.:. .:.
NP_001 KSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVD
1060 1070 1080 1090 1100 1110
1100 1110 1120 1130 1140 1150
pF1KE0 HLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKL
:: ..
NP_001 GLTTLRNGTLVAFRGHYFWMLSPFSPPSPARRITEVWGIPSPIDTVFTRCNCEGKTFFFK
1120 1130 1140 1150 1160 1170
>>NP_005798 (OMIM: 208250,604283) proteoglycan 4 isoform (1404 aa)
initn: 249 init1: 151 opt: 596 Z-score: 201.4 bits: 51.6 E(85289): 0.00018
Smith-Waterman score: 832; 24.4% identity (48.1% similar) in 1116 aa overlap (88-1102:109-1158)
60 70 80 90 100 110
pF1KE0 AVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTD
. . ::... :: : ...
NP_005 ERGRECDCDAQCKKYDKCCPDYESFCAEVHNPTSPPSSKKAPPPSG-----------ASQ
80 90 100 110 120
120 130 140 150 160 170
pF1KE0 TFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFD
:..: : . :. . :. .. :::. : : .. :. ::.. :..
NP_005 TIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQES-SSSSSSSSSSSTIRKIKS--
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 LISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPK
: . :...: :: :: :.. : . :: : :. . : : : . :
NP_005 --SKNSAANRELQKKLKV--KDNKKNRTKKKP----TPKPPVVDEAGSGLDNGDFKVTTP
190 200 210 220 230
240 250 260 270 280
pF1KE0 SISSQQPEKIKSQPP-GTGKPIQG-PTQTPQTDHAK---LPLQRDAS---------RPQT
. :. : .:....: :.:::. :. :..: .: : ...... ::
NP_005 DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT
240 250 260 270 280 290
290 300 310 320
pF1KE0 -----------KQADIVRGESVKPSLPSP---SKPPIQQPTPGKPPAQQPGHEKSQPGPA
:... .. :.: :. .:: . : : :: .: . :
NP_005 STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK
300 310 320 330 340 350
330 340 350 360 370
pF1KE0 KP----PAQP------SGLTKPLAQQPGTVK--P--PVQP-PGTTKPPAQPLGPAKPPAQ
.: : .: :. : : : :.: : : .: : ::: :: : : .:
NP_005 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA-PTTPKEPAPT
360 370 380 390 400 410
380 390 400 410 420
pF1KE0 QTGSEKPSSEQPGPKALAQP-PGVGKTPA----QQPGPAKPPTQQVGTPK---PLAQQPG
: :.. . .: . .: : . : :: ..:.:. : ::: : ...:.
NP_005 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA
420 430 440 450 460 470
430 440 450 460 470 480
pF1KE0 LQSPAKAPGPTKTPVQQPGPGKIPAQQAG--PGKTSAQQTGPTKPPSQLPGPAKPPP---
.: : :.:: : : :: . :. :.... .:: : : .: :
NP_005 PTTP-KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT
480 490 500 510 520 530
490 500 510 520 530
pF1KE0 QQPGPAKPPPQQPGSAKPPSQQPGSTKPP----PQQPGPAKP------SPQQPGSTKPPS
..:.:. . : . : :: : .:: : :..:.:. : .:..:. : :
NP_005 KEPAPTTTK-SAPTTPKEPS--PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE
540 550 560 570 580 590
540 550 560 570 580 590
pF1KE0 QQPGSAK-PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICP
: ..: :. :. :.. . : :.. . : : ..:.. . :. :. . :
NP_005 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTPEELAP
600 610 620 630 640 650
600 610 620 630 640
pF1KE0 LCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN-PN-PHLTEVKEWLCLNCQMKRALGG
:: ::. . .: : :. . . : :. : : :: :
NP_005 ---TT------PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE---------PAPTT
660 670 680 690
650 660 670 680 690 700
pF1KE0 DLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ---DLSKAPEPK---K
:.:..:. .:::.: ... . .: :.::: : ::. .: : :
NP_005 PKEPAPTTPK---ETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTSDK
700 710 720 730 740
710 720 730 740 750 760
pF1KE0 PPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP
: : . . : .:. : :. . :. :: . . .. ::.. :: :: . :
NP_005 PAPTTPKGTAPTTPKEPAPTTPKEPA---PTTPKGTAPTTLKEPAPTTPKKPA-PKELAP
750 760 770 780 790 800
770 780 790 800 810 820
pF1KE0 TTDLVSSSSATTKPDIPSSKVQSQAEEKTTP--PLKTDSAKPSQSFPPTGEKVSPFDSKA
:: .:... :: :.. .. ::: : : ::. :: .. : ..
NP_005 TTTKGPTSTTSDKP-APTTPKET---APTTPKEPAPTTPKKPA----PTTPETPPPTTSE
810 820 830 840 850
830 840 850 860 870
pF1KE0 IPRPASDSKIIS-HPGPSSESKGQKQVDPVQKKEE--PKK-----AQTKMSPKPDAKPMP
. :.. .. . : .:. :: . ...:. : : ::. ..: . ::.
NP_005 VSTPTTTKEPTTIHKSPD-ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA
860 870 880 890 900 910
880 890 900 910 920
pF1KE0 KGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITD----APKSQPTTPQETVT
: . : : : :. .:... . ... . . . : . .: ::: . .:
NP_005 KDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT
920 930 940 950 960 970
930 940 950 960 970 980
pF1KE0 GKLFGFGASIFSQASNLISTAGQPGPHSQSGPG--APMKQAPAPSQPPTSQGPPKSTGQA
: .. .. . ... .: . :. . : : ..: .:. ...: : :.
NP_005 LKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK
980 990 1000 1010 1020 1030
990 1000 1010 1020 1030 1040
pF1KE0 PPAPAKSIP-VKKETKAPAAEKLEPKA-EQAPTVKRTE----TEKKPPPIKDSKSLTAEP
: :..: :.: .:. .:. : :: . .: : .: .:: . ..:
NP_005 KP---KTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNP
1040 1050 1060 1070 1080 1090
1050 1060 1070 1080 1090
pF1KE0 QKAVLPTKLEKSP----KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTP
.. ..: .:. : ... . : . . .. :.:. .:.
NP_005 KSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVD
1100 1110 1120 1130 1140 1150
1100 1110 1120 1130 1140 1150
pF1KE0 HLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKL
:: ..
NP_005 GLTTLRNGTLVAFRGHYFWMLSPFSPPSPARRITEVWGIPSPIDTVFTRCNCEGKTFFFK
1160 1170 1180 1190 1200 1210
>>NP_001290161 (OMIM: 208250,604283) proteoglycan 4 isof (1361 aa)
initn: 249 init1: 151 opt: 572 Z-score: 194.3 bits: 50.3 E(85289): 0.00044
Smith-Waterman score: 832; 25.5% identity (48.2% similar) in 954 aa overlap (59-931:129-1044)
30 40 50 60 70 80
pF1KE0 AGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELD
. : .. :: :: .. .. ...:.
NP_001 DYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPK---PPNKKKTKKVIESEEIT
100 110 120 130 140 150
90 100 110 120 130
pF1KE0 SSHPPKQ--SGRPPDPGRP----AQPGLS----KSRTTDTFRSEQKLPGRSPSTISLKES
. :. . . : : : : ::. : : :: .... . ::. . :
NP_001 EVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI
160 170 180 190 200 210
140 150 160 170 180 190
pF1KE0 KSRTDLKEEHKSSMMPGFL--SEVNALSAVSSVVNKFNPFD----LISDSEA-SQEETTK
. : .: . .: .. .:... . ....:: . : : .:. : :.:.
NP_001 NPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA
220 230 240 250 260 270
200 210 220 230 240
pF1KE0 KQ-----KVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ---
:. ::. : : : : : : .: : . .. :: .:.:
NP_001 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP
280 290 300 310 320 330
250 260 270 280 290
pF1KE0 ----PEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQ---TKQADIVRGESVK-
: :: : .: :. : : : ...: ::.: . : .
NP_001 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT
340 350 360 370 380 390
300 310 320 330 340
pF1KE0 -PSLPSPSKPPIQQPTPGKPPA----QQPGHEKSQPGPAKP--PAQPSGLTKPLAQQPGT
:. :.:. : :: : :. ..:. ..:.:. : :: :.. :: :
NP_001 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA-PTAPKKPAPTTPKE
400 410 420 430 440 450
350 360 370 380 390 400
pF1KE0 VKP--PVQP-PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPA---
: : .: : ::: :. : : .: : : ....:.: . . : . : :.
NP_001 PAPTTPKEPAPTTTKEPS-PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT
460 470 480 490 500 510
410 420 430 440 450 460
pF1KE0 -QQPGPAKPPTQQVGTPK-PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTS
..:.:. : ::: : : .:. :. : ...:.: : . :. :.
NP_001 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP-TTPKE---PAPTT
520 530 540 550 560
470 480 490 500 510
pF1KE0 AQQTGPTKPPSQLPG-PAKPPPQQPGPAKPPPQQPGSAKPPS-QQPGSTKPPPQQPGPAK
..:.:: : . : : : : : :: : : : . ..: : :..:.:.
NP_001 PKETAPTTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPEEP--TPTTPEEPAPTT
570 580 590 600 610 620
520 530 540 550 560 570
pF1KE0 PSPQQPGSTKPPSQQPGSAK-PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAK
:. :.. : :. : . : :. :. :.. . : :.. :.. : :.. :
NP_001 PKAAAPNTPKEPA--PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA----PTTLKEPAP
630 640 650 660 670
580 590 600 610 620 630
pF1KE0 QPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLC
:.. :: . : .: : . .: .: :. . .: : .
NP_001 TTPKKPAPKELAPT-TTKEPTSTTSDKPAPTTPKGTAPTTPK----EPAPTTPKEPAPTT
680 690 700 710 720 730
640 650 660 670 680 690
pF1KE0 LNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDA--APKQDLS
. .: .:..: :: . ::.:: . .: .: .: :.::. : .::.
NP_001 PKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP
740 750 760 770 780 790
700 710 720 730
pF1KE0 KAPE------PKKPPPL---VKQPTLHGSPSAKAKQPPEADS-LS-KPAP------PKEP
.:. :. ::: :. :: :.. :.: :. :: .:.: ::::
NP_001 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP
800 810 820 830 840 850
740 750 760 770 780 790
pF1KE0 SVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD
.::. :.:.: .:.:. . : .. . : :. .. . : :: :.
NP_001 GVPTT--KTPAAT----KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTE
860 870 880 890 900
800 810 820 830 840 850
pF1KE0 S---AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEP
: : .: : . ..:: .. . :. .. .: .. ..: ::
NP_001 SKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKV------TTTKKTITTTEIMNKPEET
910 920 930 940 950 960
860 870 880 890 900
pF1KE0 KKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ---TVPT---PQQSPKPQEQSRRFS-LN
: . . . . . : :. .:: .::. . :.: :. .: :.... . ::
NP_001 AKPKDRATNSKATTPKPQ-KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELN
970 980 990 1000 1010 1020
910 920 930 940 950 960
pF1KE0 LGS-ITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA
: :..: . : :..: ..::
NP_001 PTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMD
1030 1040 1050 1060 1070 1080
>>XP_016860310 (OMIM: 188840,600334,603689,604145,608807 (34087 aa)
initn: 410 init1: 124 opt: 637 Z-score: 192.3 bits: 54.5 E(85289): 0.00057
Smith-Waterman score: 907; 23.4% identity (45.9% similar) in 1718 aa overlap (35-1578:10282-11915)
10 20 30 40 50 60
pF1KE0 ASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQ
: .: .:: ...:.. .. . : . .
XP_016 PEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKK
10260 10270 10280 10290 10300 10310
70 80 90 100 110 120
pF1KE0 GLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQK
: ..:: . . : .:. : ::. . :: :: . . ... .::.:
XP_016 EAPPAKVPEVPKKVP---EKKVL----VPKKEAVPPAKGRTVL----EEKVSVAFRQEVV
10320 10330 10340 10350 10360
130 140 150 160 170
pF1KE0 LPGRSPSTISLKESKSRTDLKEEHKSSMM--PGFLSEVNALSAVSS-VVNKFNPFD----
. : . : . . .: :. . : . ::. . . . :.. . .
XP_016 VKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHR
10370 10380 10390 10400 10410 10420
180 190 200 210 220 230
pF1KE0 LISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPK
.: :: . :. .: :. : : :: :: .. : : .:... :.. : .::
XP_016 VIEVFEAEEVEVFEKPKAPPKGPEISEKII-PP-KKPPTKVVPRKEPPAKVP----EVPK
10430 10440 10450 10460 10470
240 250 260 270 280 290
pF1KE0 SISSQQPEKIKSQP--PGTGKP-IQGPTQTPQTDHAKLPLQR--DASRPQTKQADIVRGE
.: .. .. .: : : : . : .. .. .: . .: :.. .:
XP_016 KIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVP
10480 10490 10500 10510 10520 10530
300 310 320 330 340
pF1KE0 SVKPSLPSPSKPPIQQPT--PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQ-----
: .: :.:: . :: : : : : .. . : :: . : . . : .
XP_016 EKKVPVPPPKKPEVP-PTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEVLPPKEVVPE
10540 10550 10560 10570 10580 10590
350 360 370 380
pF1KE0 -----PGTVKPPVQPPGTTK-P-------------PAQPLGP-AKPP--AQQTGSEK--P
: . :: . :: . . : : .: .: :: : ::.. :: :
XP_016 KKVPVPPAKKPEAPPPKVPEAPKEVVLEKKASVAVPKKPEAPRAKVPEAAQEVVPEKKIP
10600 10610 10620 10630 10640 10650
390 400 410 420 430
pF1KE0 SSEQPGPKALAQP-PGVGKTPAQQPGPAKPPTQQVG--TPKPLAQQ--PGLQSPAKAPGP
.. :.: : : : . :.. :. :: . . .: : ::. : . : ::: :
XP_016 KAPIKKPEAPAVTVPEVPQEAAEKEIPVAPPKKPEAPIVPVPEAQEVVPEKKVP-KAP-P
10660 10670 10680 10690 10700 10710
440 450 460 470 480
pF1KE0 TKTPVQQPGP-GKIPAQQAGPGKTSAQQTGPTKPPSQLP-GPA-----KPPPQQPG--PA
:: : :. ..: . . :: . : :: .: .: : :. : :
XP_016 TK-PEAPPATVPEVPQEIVPEKKTLVLPKKPEVPPVTVPEAPKEVVLEKKVPSTPPKKPE
10720 10730 10740 10750 10760 10770
490 500 510 520 530 540
pF1KE0 KPP---PQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSPQQPGSTKPPSQQPGSAKPSAQQ
:: :. : . : .. : :::..: : :. : .. : .. : . :. ..
XP_016 VPPVKVPEAPKEVVPEKKVP---VPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPES
10780 10790 10800 10810 10820
550 560 570 580 590 600
pF1KE0 PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPE
: : : . . : . . :. ::. .: : : :: . ... . . ::
XP_016 PPPEVPEVLPPKEVVPE--KKVPV-PPAKKPEAPPPKVPEAPKEVVLEKKVSVAVPKKPE
10830 10840 10850 10860 10870 10880
610 620 630 640 650
pF1KE0 KANFNTCTECQTTV-CSLCGFNP-----NPHLT--EVKEWLC---LNCQMKRALGGDLAP
.. : .: . : : .: :: . . . . ..:
XP_016 APRAKVPEAAQEVVPEKKIPKAPIKKPEAPAVTVPEVPQEAAEKEIPVAPPKKPEAPIVP
10890 10900 10910 10920 10930 10940
660 670 680 690 700
pF1KE0 VPSS----PQPKLKTAPVTTTSAVSKSSPQ-PQQTSPKKDAA--PKQ-DLSKAPEPKKPP
:: . :. :. :: : : . :. ::. :.: . ::. .. . :. :
XP_016 VPEAQEVVPEKKVPKAPPTKPEAPPATVPEVPQEIVPEKKTLVLPKKPEVPPVTVPEAPK
10950 10960 10970 10980 10990 11000
710 720 730 740 750
pF1KE0 PLVKQPTLHGSPSAKAKQPP----EADSLSKP------APPKEPSVPSEQ-DKAPVADDK
.: . . .: : . :: :: . : .:::.: :: . .::.
XP_016 EVVLEKKVPLAPPKKPEVPPVKVPEAPKEVVPEKKVPVTPPKKPEVPPVKVPEAPIEVVP
11010 11020 11030 11040 11050 11060
760 770 780 790 800
pF1KE0 PKQPKMVKPTTDLVSSSSATTKPD--IPSSKVQSQAEEKT-TPPLKTDSA-------KPS
:. .. : : .. : .: .:: : .: .::.:. : :
XP_016 EKKMPLAPPKKPEVPPVKVPEAPKEVVPEKKVPSAPPKKPEVPPVKVPEAPKEVVPEKKV
11070 11080 11090 11100 11110 11120
810 820 830 840 850 860
pF1KE0 QSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEP-KKAQTKM
. :: .:.: :. . : . : :.. .: : : : ::. .
XP_016 PAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAI
11130 11140 11150 11160 11170 11180
870 880 890 900 910
pF1KE0 SPKPDAKP-----MPK--GSPTPPG-----PRPTAGQTVPTPQQSPKPQEQSRRFSLNLG
:::.. : :. . ::. :.:.: : .: ..: :.... .
XP_016 PPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKP
11190 11200 11210 11220 11230 11240
920 930 940 950 960 970
pF1KE0 SITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAP
. : . : .:.:.: : . . .: : : .. .: :.. .:
XP_016 EL--PPVKVPEVPKEVVPEKKVPLVVPKKPEAP----PAKVPEVPKEV---VPEKKVAVP
11250 11260 11270 11280 11290
980 990 1000 1010 1020
pF1KE0 SQPPTSQGPPKSTGQAPPAPA----KSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKK
..: . :: .. ..: :. ..:: .....: : : : :: . . :.:
XP_016 KKPEV---PPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEK
11300 11310 11320 11330 11340 11350
1030 1040 1050 1060 1070 1080
pF1KE0 PPPIKDSKSLTAEPQKAVLPTKLEKSPK---PESTCPLCKTELNIGSKDPPNFNTCTECK
: :. . . ::. : : . . :: ::. :. : :.: . . :
XP_016 PVPVAEEE----EPE--VPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEMPKKVVPVK
11360 11370 11380 11390 11400
1090 1100 1110 1120 1130 1140
pF1KE0 NQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP-PAPSGPKASPMPVPTE
. .:. .. :. . .: ..: : :. . :.. : ::
XP_016 KVPTVKKPETPAAKVPEVPK--------------KLVPVKKEPVPVTKKPEVLPEKVPKV
11410 11420 11430 11440 11450
1150 1160 1170 1180 1190
pF1KE0 SSS----QKTAVP-PQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEE
. ....:: : : : : .: : . ::.. :.. .. ::. ::
XP_016 PEKIIPEKEVSVPIPAEPEVPPAEVE-ETPEEIIYEEKASITIGRKETPPV-------EE
11460 11470 11480 11490 11500
1200 1210 1220 1230 1240
pF1KE0 SKLEKDKASALQEKKPLPEEKKLI-PEEEKIRSEEK-KPLLEEKKPTP--ED--------
..:: : .: ::: . :: ::. . : :: :.: ::
XP_016 REIEKYIKPEEPEPEPQPEEIPVKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQL
11510 11520 11530 11540 11550 11560
1250 1260 1270 1280 1290
pF1KE0 ----KKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQP---QTKMEGL
:: .:: : ..:: : .: .: .:.:.. .. :. : :. .. ..
XP_016 KAIPKKKVPE-KPQVPE--KVELTPLKVPGGEKKVR-KLLPERKPEPKEEVVLKSVLRKR
11570 11580 11590 11600 11610 11620
1300 1310 1320 1330 1340 1350
pF1KE0 PSGT-PQSLPKEDDKTTKTIKEQPQPPCTAKP-DQVE-PGKEKTEKEDDKSDTSSSQQPK
: :. ::. .:. : .: :: :: ..:: : : :.. . .:
XP_016 PEEEEPKVEPKKLEKVKKPAVPEPPPP---KPVEEVEVPTVTKRERKIPEPTKVPEIKPA
11630 11640 11650 11660 11670
1360 1370 1380 1390 1400 1410
pF1KE0 SPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSD-LAKLES
: . . .. ... : . . : . .... ..:.. :: ..
XP_016 IPLPAPEPKPKPEAEVKTIKPPP--VEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKG
11680 11690 11700 11710 11720 11730
1420 1430 1440 1450 1460
pF1KE0 TVLSILEAQASTLADEKSEKKTQPHEVSPEQPKD------QEKTQSLS---ETLEITISE
. .. . : . :. .: .: . :.: : : :. :. : .: ..:
XP_016 PIKGVPKKTPSPIEAER--RKLRPGS-GGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTE
11740 11750 11760 11770 11780 11790
1470 1480 1490 1500 1510
pF1KE0 EE------IKE---SQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEES
: : : : :. ::.. .: : :. :. : :. .:. :
XP_016 SEFVGSSAIFECLVSPSTAITTWMKDGS-NIRESPKHR----FIADGKDRKLHIIDVQLS
11800 11810 11820 11830 11840
1520 1530 1540 1550 1560 1570
pF1KE0 SESENSPVPQ--RKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQII----EMSADEDAS
. .: . : . :..::... .: . . :: .. : . :.. ..:.
XP_016 DAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDVV
11850 11860 11870 11880 11890 11900
1580 1590 1600 1610 1620 1630
pF1KE0 GSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWH
.: ...
XP_016 WRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEV
11910 11920 11930 11940 11950 11960
5143 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 20:09:18 2016 done: Sun Nov 6 20:09:25 2016
Total Scan time: 43.440 Total Display time: 4.420
Function used was FASTA [36.3.4 Apr, 2011]