FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0301, 509 aa 1>>>pF1KE0301 509 - 509 aa - 509 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7866+/-0.000505; mu= 15.5236+/- 0.031 mean_var=75.6707+/-15.972, 0's: 0 Z-trim(108.8): 134 B-trim: 330 in 1/48 Lambda= 0.147438 statistics sampled from 16815 (16960) to 16815 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.551), E-opt: 0.2 (0.199), width: 16 Scan time: 9.300 The best scores are: opt bits E(85289) NP_036575 (OMIM: 605730) sperm-associated antigen ( 509) 3251 701.7 1.3e-201 XP_005252702 (OMIM: 605730) PREDICTED: sperm-assoc ( 506) 3101 669.8 5.2e-192 NP_001240783 (OMIM: 605730) sperm-associated antig ( 484) 3006 649.6 6.1e-186 NP_001240784 (OMIM: 605730) sperm-associated antig ( 484) 2960 639.8 5.4e-183 NP_758442 (OMIM: 605730) sperm-associated antigen ( 458) 2793 604.2 2.5e-172 XP_005252703 (OMIM: 605730) PREDICTED: sperm-assoc ( 451) 1467 322.2 2e-87 XP_016866329 (OMIM: 604545) PREDICTED: importin su ( 536) 289 71.7 6.3e-12 XP_016866328 (OMIM: 604545) PREDICTED: importin su ( 539) 289 71.7 6.3e-12 NP_002260 (OMIM: 604545) importin subunit alpha-6 ( 539) 289 71.7 6.3e-12 XP_011534107 (OMIM: 604545) PREDICTED: importin su ( 559) 289 71.7 6.5e-12 XP_016866327 (OMIM: 604545) PREDICTED: importin su ( 559) 289 71.7 6.5e-12 NP_002259 (OMIM: 602970) importin subunit alpha-3 ( 521) 283 70.4 1.5e-11 XP_011511097 (OMIM: 600686) PREDICTED: importin su ( 477) 281 69.9 1.8e-11 XP_005247494 (OMIM: 600686) PREDICTED: importin su ( 538) 281 70.0 2e-11 NP_002255 (OMIM: 600686) importin subunit alpha-5 ( 538) 281 70.0 2e-11 XP_016867704 (OMIM: 614107) PREDICTED: importin su ( 487) 280 69.7 2.2e-11 NP_036448 (OMIM: 610563) importin subunit alpha-7 ( 536) 269 67.4 1.2e-10 XP_005270768 (OMIM: 610563) PREDICTED: importin su ( 566) 269 67.4 1.2e-10 XP_016861854 (OMIM: 600686) PREDICTED: importin su ( 337) 241 61.3 5e-09 XP_016861852 (OMIM: 600686) PREDICTED: importin su ( 337) 241 61.3 5e-09 XP_005247496 (OMIM: 600686) PREDICTED: importin su ( 337) 241 61.3 5e-09 XP_011511099 (OMIM: 600686) PREDICTED: importin su ( 337) 241 61.3 5e-09 XP_016861853 (OMIM: 600686) PREDICTED: importin su ( 337) 241 61.3 5e-09 NP_002257 (OMIM: 600685) importin subunit alpha-1 ( 529) 228 58.7 5e-08 NP_001307540 (OMIM: 600685) importin subunit alpha ( 529) 228 58.7 5e-08 XP_016866330 (OMIM: 604545) PREDICTED: importin su ( 332) 210 54.8 4.8e-07 XP_016867705 (OMIM: 614107) PREDICTED: importin su ( 425) 209 54.6 6.8e-07 XP_016866331 (OMIM: 604545) PREDICTED: importin su ( 327) 207 54.1 7.3e-07 XP_016866332 (OMIM: 604545) PREDICTED: importin su ( 327) 207 54.1 7.3e-07 NP_001139187 (OMIM: 614107) importin subunit alpha ( 516) 209 54.6 8e-07 XP_016867703 (OMIM: 614107) PREDICTED: importin su ( 521) 209 54.6 8.1e-07 XP_016867702 (OMIM: 614107) PREDICTED: importin su ( 521) 209 54.6 8.1e-07 XP_016867701 (OMIM: 614107) PREDICTED: importin su ( 521) 209 54.6 8.1e-07 XP_016867700 (OMIM: 614107) PREDICTED: importin su ( 522) 209 54.6 8.1e-07 XP_016867699 (OMIM: 614107) PREDICTED: importin su ( 537) 209 54.6 8.3e-07 XP_011514517 (OMIM: 614107) PREDICTED: importin su ( 543) 209 54.6 8.4e-07 XP_016867697 (OMIM: 614107) PREDICTED: importin su ( 548) 209 54.6 8.4e-07 XP_016867698 (OMIM: 614107) PREDICTED: importin su ( 544) 193 51.2 8.9e-06 XP_016876050 (OMIM: 601892) PREDICTED: importin su ( 497) 184 49.3 3.1e-05 NP_002258 (OMIM: 601892) importin subunit alpha-4 ( 521) 184 49.3 3.2e-05 XP_016858908 (OMIM: 609803) PREDICTED: ankyrin and ( 898) 183 49.2 6e-05 XP_011508976 (OMIM: 609803) PREDICTED: ankyrin and (1434) 183 49.3 8.9e-05 NP_653309 (OMIM: 609803) ankyrin and armadillo rep (1434) 183 49.3 8.9e-05 XP_016858909 (OMIM: 609803) PREDICTED: ankyrin and ( 738) 150 42.2 0.0065 XP_016871860 (OMIM: 615408,615451) PREDICTED: arma ( 701) 149 41.9 0.0072 XP_011517837 (OMIM: 615408,615451) PREDICTED: arma ( 702) 149 41.9 0.0073 NP_001299618 (OMIM: 615408,615451) armadillo repea ( 736) 149 41.9 0.0076 XP_011517836 (OMIM: 615408,615451) PREDICTED: arma ( 756) 149 42.0 0.0077 XP_011517835 (OMIM: 615408,615451) PREDICTED: arma ( 756) 149 42.0 0.0077 XP_016858907 (OMIM: 609803) PREDICTED: ankyrin and ( 909) 150 42.2 0.0078 >>NP_036575 (OMIM: 605730) sperm-associated antigen 6 is (509 aa) initn: 3251 init1: 3251 opt: 3251 Z-score: 3740.5 bits: 701.7 E(85289): 1.3e-201 Smith-Waterman score: 3251; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:1-509) 10 20 30 40 50 60 pF1KE0 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC 430 440 450 460 470 480 490 500 pF1KE0 YPEEIVRYYSPGYSDTLLQRVDSYQPLNN ::::::::::::::::::::::::::::: NP_036 YPEEIVRYYSPGYSDTLLQRVDSYQPLNN 490 500 >>XP_005252702 (OMIM: 605730) PREDICTED: sperm-associate (506 aa) initn: 3773 init1: 3101 opt: 3101 Z-score: 3568.2 bits: 669.8 E(85289): 5.2e-192 Smith-Waterman score: 3101; 99.2% identity (99.4% similar) in 491 aa overlap (1-491:1-491) 10 20 30 40 50 60 pF1KE0 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC 430 440 450 460 470 480 490 500 pF1KE0 YPEEIVRYYSPGYSDTLLQRVDSYQPLNN :::::: . : XP_005 YPEEIVSKFFPELQVCALFRKFMRTP 490 500 >>NP_001240783 (OMIM: 605730) sperm-associated antigen 6 (484 aa) initn: 3006 init1: 3006 opt: 3006 Z-score: 3459.2 bits: 649.6 E(85289): 6.1e-186 Smith-Waterman score: 3006; 100.0% identity (100.0% similar) in 470 aa overlap (40-509:15-484) 10 20 30 40 50 60 pF1KE0 FEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLA :::::::::::::::::::::::::::::: NP_001 MHSLTMDLWIPNGQAGVMSLLRTLLLDVVPTIQQTAALALGRLA 10 20 30 40 70 80 90 100 110 120 pF1KE0 NYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDT 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 LVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAAS 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 ALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVE 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 AEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNT 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE0 RLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPE 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE0 HARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPFLYDAPPNIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPFLYDAPPNIL 350 360 370 380 390 400 430 440 450 460 470 480 pF1KE0 KHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSCYPEEIVRYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSCYPEEIVRYY 410 420 430 440 450 460 490 500 pF1KE0 SPGYSDTLLQRVDSYQPLNN :::::::::::::::::::: NP_001 SPGYSDTLLQRVDSYQPLNN 470 480 >>NP_001240784 (OMIM: 605730) sperm-associated antigen 6 (484 aa) initn: 3632 init1: 2960 opt: 2960 Z-score: 3406.4 bits: 639.8 E(85289): 5.4e-183 Smith-Waterman score: 2960; 99.1% identity (99.4% similar) in 469 aa overlap (23-491:1-469) 10 20 30 40 50 60 pF1KE0 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT :::::::::::::::::::::::::::::::::::::: NP_001 MVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT 10 20 30 70 80 90 100 110 120 pF1KE0 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE0 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE0 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC 400 410 420 430 440 450 490 500 pF1KE0 YPEEIVRYYSPGYSDTLLQRVDSYQPLNN :::::: . : NP_001 YPEEIVSKFFPELQVCALFRKFMRTP 460 470 480 >>NP_758442 (OMIM: 605730) sperm-associated antigen 6 is (458 aa) initn: 2793 init1: 2793 opt: 2793 Z-score: 3214.7 bits: 604.2 E(85289): 2.5e-172 Smith-Waterman score: 2793; 100.0% identity (100.0% similar) in 440 aa overlap (1-440:1-440) 10 20 30 40 50 60 pF1KE0 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC :::::::::::::::::::: NP_758 LYDAPPNILKHVVGQFSKVLFPWIFRYTSAEGGQLSTT 430 440 450 >>XP_005252703 (OMIM: 605730) PREDICTED: sperm-associate (451 aa) initn: 1467 init1: 1467 opt: 1467 Z-score: 1690.5 bits: 322.2 E(85289): 2e-87 Smith-Waterman score: 2765; 88.6% identity (88.6% similar) in 509 aa overlap (1-509:1-451) 10 20 30 40 50 60 pF1KE0 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS :::::::::::::::::::::::::::::::::::::::::::::: XP_005 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLK-------------- 190 200 210 220 250 260 270 280 290 300 pF1KE0 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID :::::::::::::::: XP_005 --------------------------------------------LSQLVVNAGGVAAVID 230 240 310 320 330 340 350 360 pF1KE0 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL 250 260 270 280 290 300 370 380 390 400 410 420 pF1KE0 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF 310 320 330 340 350 360 430 440 450 460 470 480 pF1KE0 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC 370 380 390 400 410 420 490 500 pF1KE0 YPEEIVRYYSPGYSDTLLQRVDSYQPLNN ::::::::::::::::::::::::::::: XP_005 YPEEIVRYYSPGYSDTLLQRVDSYQPLNN 430 440 450 >>XP_016866329 (OMIM: 604545) PREDICTED: importin subuni (536 aa) initn: 333 init1: 169 opt: 289 Z-score: 335.2 bits: 71.7 E(85289): 6.3e-12 Smith-Waterman score: 289; 25.0% identity (58.7% similar) in 264 aa overlap (41-300:167-428) 20 30 40 50 60 70 pF1KE0 EQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLAN :.. .. :: . .:. :. ::: .:. XP_016 ENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAG 140 150 160 170 180 190 80 90 100 110 120 pF1KE0 YNDDLAEAVVKCDILPQLVYSLAEQNRFYK-KAAAFVLRAV--GKHSPQLAQAIVDCGAL : . . :..:.::: :. :...::. . :...: . ::. : . . : : XP_016 DNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPC--L 200 210 220 230 240 250 130 140 150 160 170 180 pF1KE0 DTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIA ..: : . :: : . ::: :.. . :::.:.:. :: ... . . : XP_016 NVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPA 260 270 280 290 300 310 190 200 210 220 230 240 pF1KE0 ASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMV :...:. . .:.... .:. : ... .: ..... ..:... . . : XP_016 LRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAV 320 330 340 350 360 370 250 260 270 280 290 300 pF1KE0 VEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKH-TPELSQLVVNAGGVAAVIDCIGSCK ..:.::::.. :. . ..:.:. : . .. ::: . .: : . . : XP_016 IDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMD 380 390 400 410 420 430 310 320 330 340 350 360 pF1KE0 GNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQIGRH XP_016 SKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQSHENQEIYQKA 440 450 460 470 480 490 >>XP_016866328 (OMIM: 604545) PREDICTED: importin subuni (539 aa) initn: 262 init1: 169 opt: 289 Z-score: 335.1 bits: 71.7 E(85289): 6.3e-12 Smith-Waterman score: 289; 25.0% identity (58.7% similar) in 264 aa overlap (41-300:170-431) 20 30 40 50 60 70 pF1KE0 EQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLAN :.. .. :: . .:. :. ::: .:. XP_016 ENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAG 140 150 160 170 180 190 80 90 100 110 120 pF1KE0 YNDDLAEAVVKCDILPQLVYSLAEQNRFYK-KAAAFVLRAV--GKHSPQLAQAIVDCGAL : . . :..:.::: :. :...::. . :...: . ::. : . . : : XP_016 DNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPC--L 200 210 220 230 240 250 130 140 150 160 170 180 pF1KE0 DTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIA ..: : . :: : . ::: :.. . :::.:.:. :: ... . . : XP_016 NVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPA 260 270 280 290 300 310 190 200 210 220 230 240 pF1KE0 ASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMV :...:. . .:.... .:. : ... .: ..... ..:... . . : XP_016 LRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAV 320 330 340 350 360 370 250 260 270 280 290 300 pF1KE0 VEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKH-TPELSQLVVNAGGVAAVIDCIGSCK ..:.::::.. :. . ..:.:. : . .. ::: . .: : . . : XP_016 IDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMD 380 390 400 410 420 430 310 320 330 340 350 360 pF1KE0 GNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQIGRH XP_016 SKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQSHENQEIYQKA 440 450 460 470 480 490 >>NP_002260 (OMIM: 604545) importin subunit alpha-6 [Hom (539 aa) initn: 262 init1: 169 opt: 289 Z-score: 335.1 bits: 71.7 E(85289): 6.3e-12 Smith-Waterman score: 289; 25.0% identity (58.7% similar) in 264 aa overlap (41-300:170-431) 20 30 40 50 60 70 pF1KE0 EQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLAN :.. .. :: . .:. :. ::: .:. NP_002 ENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAG 140 150 160 170 180 190 80 90 100 110 120 pF1KE0 YNDDLAEAVVKCDILPQLVYSLAEQNRFYK-KAAAFVLRAV--GKHSPQLAQAIVDCGAL : . . :..:.::: :. :...::. . :...: . ::. : . . : : NP_002 DNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPC--L 200 210 220 230 240 250 130 140 150 160 170 180 pF1KE0 DTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIA ..: : . :: : . ::: :.. . :::.:.:. :: ... . . : NP_002 NVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPA 260 270 280 290 300 310 190 200 210 220 230 240 pF1KE0 ASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMV :...:. . .:.... .:. : ... .: ..... ..:... . . : NP_002 LRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAV 320 330 340 350 360 370 250 260 270 280 290 300 pF1KE0 VEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKH-TPELSQLVVNAGGVAAVIDCIGSCK ..:.::::.. :. . ..:.:. : . .. ::: . .: : . . : NP_002 IDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMD 380 390 400 410 420 430 310 320 330 340 350 360 pF1KE0 GNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQIGRH NP_002 SKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQSHENQEIYQKA 440 450 460 470 480 490 >>XP_011534107 (OMIM: 604545) PREDICTED: importin subuni (559 aa) initn: 333 init1: 169 opt: 289 Z-score: 334.9 bits: 71.7 E(85289): 6.5e-12 Smith-Waterman score: 289; 25.0% identity (58.7% similar) in 264 aa overlap (41-300:190-451) 20 30 40 50 60 70 pF1KE0 EQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLAN :.. .. :: . .:. :. ::: .:. XP_011 ENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAG 160 170 180 190 200 210 80 90 100 110 120 pF1KE0 YNDDLAEAVVKCDILPQLVYSLAEQNRFYK-KAAAFVLRAV--GKHSPQLAQAIVDCGAL : . . :..:.::: :. :...::. . :...: . ::. : . . : : XP_011 DNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPC--L 220 230 240 250 260 270 130 140 150 160 170 180 pF1KE0 DTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIA ..: : . :: : . ::: :.. . :::.:.:. :: ... . . : XP_011 NVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPA 280 290 300 310 320 330 190 200 210 220 230 240 pF1KE0 ASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMV :...:. . .:.... .:. : ... .: ..... ..:... . . : XP_011 LRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAV 340 350 360 370 380 390 250 260 270 280 290 300 pF1KE0 VEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKH-TPELSQLVVNAGGVAAVIDCIGSCK ..:.::::.. :. . ..:.:. : . .. ::: . .: : . . : XP_011 IDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMD 400 410 420 430 440 450 310 320 330 340 350 360 pF1KE0 GNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQIGRH XP_011 SKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQSHENQEIYQKA 460 470 480 490 500 510 509 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 17:26:39 2016 done: Thu Nov 3 17:26:40 2016 Total Scan time: 9.300 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]