FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0302, 476 aa 1>>>pF1KE0302 476 - 476 aa - 476 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0430+/-0.000412; mu= 19.4890+/- 0.025 mean_var=69.2424+/-14.580, 0's: 0 Z-trim(110.2): 90 B-trim: 1269 in 1/53 Lambda= 0.154130 statistics sampled from 18437 (18536) to 18437 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.58), E-opt: 0.2 (0.217), width: 16 Scan time: 8.920 The best scores are: opt bits E(85289) XP_016864705 (OMIM: 606561) PREDICTED: proton-coup ( 476) 3147 709.4 5.6e-204 XP_011535886 (OMIM: 606561) PREDICTED: proton-coup ( 476) 3147 709.4 5.6e-204 XP_011535893 (OMIM: 606561) PREDICTED: proton-coup ( 476) 3147 709.4 5.6e-204 NP_510968 (OMIM: 606561) proton-coupled amino acid ( 476) 3147 709.4 5.6e-204 XP_011535892 (OMIM: 606561) PREDICTED: proton-coup ( 476) 3147 709.4 5.6e-204 XP_011535885 (OMIM: 606561) PREDICTED: proton-coup ( 476) 3147 709.4 5.6e-204 XP_011535883 (OMIM: 606561) PREDICTED: proton-coup ( 476) 3147 709.4 5.6e-204 XP_011535891 (OMIM: 606561) PREDICTED: proton-coup ( 476) 3147 709.4 5.6e-204 XP_011535889 (OMIM: 606561) PREDICTED: proton-coup ( 476) 3147 709.4 5.6e-204 XP_011535887 (OMIM: 606561) PREDICTED: proton-coup ( 476) 3147 709.4 5.6e-204 XP_005268443 (OMIM: 606561) PREDICTED: proton-coup ( 476) 3147 709.4 5.6e-204 XP_011535894 (OMIM: 606561) PREDICTED: proton-coup ( 476) 3147 709.4 5.6e-204 XP_011535888 (OMIM: 606561) PREDICTED: proton-coup ( 476) 3147 709.4 5.6e-204 XP_011535890 (OMIM: 606561) PREDICTED: proton-coup ( 476) 3147 709.4 5.6e-204 XP_011535882 (OMIM: 606561) PREDICTED: proton-coup ( 482) 3147 709.4 5.7e-204 XP_006714822 (OMIM: 606561) PREDICTED: proton-coup ( 398) 2635 595.4 9.1e-170 XP_011535895 (OMIM: 606561) PREDICTED: proton-coup ( 448) 2635 595.5 1e-169 XP_011535896 (OMIM: 606561) PREDICTED: proton-coup ( 448) 2635 595.5 1e-169 XP_016864706 (OMIM: 606561) PREDICTED: proton-coup ( 418) 2593 586.1 6.2e-167 XP_011535897 (OMIM: 606561) PREDICTED: proton-coup ( 422) 2593 586.1 6.2e-167 NP_001295079 (OMIM: 606561) proton-coupled amino a ( 386) 2588 585.0 1.3e-166 XP_016864707 (OMIM: 606561) PREDICTED: proton-coup ( 362) 2209 500.7 2.8e-141 NP_861441 (OMIM: 138500,242600,608331) proton-coup ( 483) 2199 498.6 1.6e-140 XP_016864708 (OMIM: 606561) PREDICTED: proton-coup ( 323) 2081 472.2 9.4e-133 NP_861439 (OMIM: 608332) proton-coupled amino acid ( 470) 1921 436.7 6.5e-122 XP_005268434 (OMIM: 138500,242600,608331) PREDICTE ( 393) 1759 400.7 3.9e-111 NP_001295080 (OMIM: 606561) proton-coupled amino a ( 243) 1605 366.3 5.5e-101 XP_016864709 (OMIM: 606561) PREDICTED: proton-coup ( 243) 1605 366.3 5.5e-101 XP_011535898 (OMIM: 606561) PREDICTED: proton-coup ( 298) 1605 366.3 6.5e-101 NP_689526 (OMIM: 613760) proton-coupled amino acid ( 504) 1603 366.0 1.3e-100 XP_011535933 (OMIM: 608332) PREDICTED: proton-coup ( 355) 1552 354.6 2.6e-97 XP_011535932 (OMIM: 608332) PREDICTED: proton-coup ( 355) 1552 354.6 2.6e-97 NP_001138489 (OMIM: 608332) proton-coupled amino a ( 511) 1451 332.2 2e-90 XP_016864573 (OMIM: 138500,242600,608331) PREDICTE ( 285) 1382 316.7 5.3e-86 XP_016872664 (OMIM: 613760) PREDICTED: proton-coup ( 398) 1342 307.9 3.3e-83 XP_016872663 (OMIM: 613760) PREDICTED: proton-coup ( 407) 1336 306.6 8.3e-83 XP_011535931 (OMIM: 608332) PREDICTED: proton-coup ( 364) 1315 301.9 1.9e-81 XP_011535935 (OMIM: 608332) PREDICTED: proton-coup ( 307) 1306 299.8 6.8e-81 XP_016864572 (OMIM: 138500,242600,608331) PREDICTE ( 310) 1265 290.7 3.8e-78 NP_001273068 (OMIM: 613760) proton-coupled amino a ( 369) 1240 285.2 2.1e-76 XP_016872665 (OMIM: 613760) PREDICTED: proton-coup ( 369) 1240 285.2 2.1e-76 XP_006714819 (OMIM: 138500,242600,608331) PREDICTE ( 450) 1100 254.2 5.7e-67 XP_011535929 (OMIM: 608332) PREDICTED: proton-coup ( 444) 1063 245.9 1.7e-64 XP_016872666 (OMIM: 613760) PREDICTED: proton-coup ( 272) 973 225.8 1.2e-58 XP_011535936 (OMIM: 608332) PREDICTED: proton-coup ( 249) 615 146.1 1e-34 XP_016878882 (OMIM: 614236) PREDICTED: putative so ( 462) 194 52.7 2.6e-06 NP_060701 (OMIM: 614236) putative sodium-coupled n ( 462) 194 52.7 2.6e-06 NP_542119 (OMIM: 616440) vesicular inhibitory amin ( 525) 193 52.5 3.3e-06 XP_016858952 (OMIM: 616526) PREDICTED: putative so ( 340) 180 49.5 1.7e-05 NP_775783 (OMIM: 616526) putative sodium-coupled n ( 384) 180 49.5 1.9e-05 >>XP_016864705 (OMIM: 606561) PREDICTED: proton-coupled (476 aa) initn: 3147 init1: 3147 opt: 3147 Z-score: 3783.0 bits: 709.4 E(85289): 5.6e-204 Smith-Waterman score: 3147; 99.8% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KE0 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLASLVMIYQFIV :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: XP_016 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI 430 440 450 460 470 >>XP_011535886 (OMIM: 606561) PREDICTED: proton-coupled (476 aa) initn: 3147 init1: 3147 opt: 3147 Z-score: 3783.0 bits: 709.4 E(85289): 5.6e-204 Smith-Waterman score: 3147; 99.8% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KE0 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLASLVMIYQFIV :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: XP_011 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI 430 440 450 460 470 >>XP_011535893 (OMIM: 606561) PREDICTED: proton-coupled (476 aa) initn: 3147 init1: 3147 opt: 3147 Z-score: 3783.0 bits: 709.4 E(85289): 5.6e-204 Smith-Waterman score: 3147; 99.8% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KE0 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLASLVMIYQFIV :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: XP_011 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI 430 440 450 460 470 >>NP_510968 (OMIM: 606561) proton-coupled amino acid tra (476 aa) initn: 3147 init1: 3147 opt: 3147 Z-score: 3783.0 bits: 709.4 E(85289): 5.6e-204 Smith-Waterman score: 3147; 99.8% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KE0 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_510 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_510 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_510 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLASLVMIYQFIV :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: NP_510 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_510 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_510 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_510 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_510 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI 430 440 450 460 470 >>XP_011535892 (OMIM: 606561) PREDICTED: proton-coupled (476 aa) initn: 3147 init1: 3147 opt: 3147 Z-score: 3783.0 bits: 709.4 E(85289): 5.6e-204 Smith-Waterman score: 3147; 99.8% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KE0 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLASLVMIYQFIV :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: XP_011 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI 430 440 450 460 470 >>XP_011535885 (OMIM: 606561) PREDICTED: proton-coupled (476 aa) initn: 3147 init1: 3147 opt: 3147 Z-score: 3783.0 bits: 709.4 E(85289): 5.6e-204 Smith-Waterman score: 3147; 99.8% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KE0 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLASLVMIYQFIV :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: XP_011 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI 430 440 450 460 470 >>XP_011535883 (OMIM: 606561) PREDICTED: proton-coupled (476 aa) initn: 3147 init1: 3147 opt: 3147 Z-score: 3783.0 bits: 709.4 E(85289): 5.6e-204 Smith-Waterman score: 3147; 99.8% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KE0 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLASLVMIYQFIV :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: XP_011 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI 430 440 450 460 470 >>XP_011535891 (OMIM: 606561) PREDICTED: proton-coupled (476 aa) initn: 3147 init1: 3147 opt: 3147 Z-score: 3783.0 bits: 709.4 E(85289): 5.6e-204 Smith-Waterman score: 3147; 99.8% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KE0 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLASLVMIYQFIV :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: XP_011 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI 430 440 450 460 470 >>XP_011535889 (OMIM: 606561) PREDICTED: proton-coupled (476 aa) initn: 3147 init1: 3147 opt: 3147 Z-score: 3783.0 bits: 709.4 E(85289): 5.6e-204 Smith-Waterman score: 3147; 99.8% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KE0 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLASLVMIYQFIV :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: XP_011 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI 430 440 450 460 470 >>XP_011535887 (OMIM: 606561) PREDICTED: proton-coupled (476 aa) initn: 3147 init1: 3147 opt: 3147 Z-score: 3783.0 bits: 709.4 E(85289): 5.6e-204 Smith-Waterman score: 3147; 99.8% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KE0 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLASLVMIYQFIV :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: XP_011 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI 430 440 450 460 470 476 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 17:20:00 2016 done: Thu Nov 3 17:20:02 2016 Total Scan time: 8.920 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]