FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0305, 652 aa 1>>>pF1KE0305 652 - 652 aa - 652 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8275+/-0.000919; mu= 10.4036+/- 0.055 mean_var=242.8910+/-47.275, 0's: 0 Z-trim(114.5): 183 B-trim: 47 in 1/53 Lambda= 0.082294 statistics sampled from 14824 (15021) to 14824 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.461), width: 16 Scan time: 4.490 The best scores are: opt bits E(32554) CCDS13149.1 CD93 gene_id:22918|Hs108|chr20 ( 652) 4648 565.2 9.8e-161 CCDS74370.1 LTBP4 gene_id:8425|Hs108|chr19 (1557) 549 79.0 5.4e-14 CCDS74368.1 LTBP4 gene_id:8425|Hs108|chr19 (1587) 549 79.0 5.5e-14 CCDS74369.1 LTBP4 gene_id:8425|Hs108|chr19 (1624) 549 79.0 5.6e-14 CCDS54345.1 LTBP1 gene_id:4052|Hs108|chr2 (1342) 540 77.9 1e-13 CCDS54344.1 LTBP1 gene_id:4052|Hs108|chr2 (1353) 540 77.9 1e-13 CCDS33178.2 LTBP1 gene_id:4052|Hs108|chr2 (1395) 540 77.9 1.1e-13 CCDS33177.2 LTBP1 gene_id:4052|Hs108|chr2 (1721) 540 78.0 1.2e-13 CCDS8103.1 LTBP3 gene_id:4054|Hs108|chr11 (1256) 537 77.5 1.3e-13 CCDS44647.1 LTBP3 gene_id:4054|Hs108|chr11 (1303) 537 77.5 1.3e-13 CCDS8134.1 CD248 gene_id:57124|Hs108|chr11 ( 757) 526 75.9 2.3e-13 CCDS8002.1 VWCE gene_id:220001|Hs108|chr11 ( 955) 522 75.6 3.6e-13 CCDS43028.1 FBLN1 gene_id:2192|Hs108|chr22 ( 566) 504 73.2 1.1e-12 CCDS8116.1 EFEMP2 gene_id:30008|Hs108|chr11 ( 443) 502 72.8 1.2e-12 CCDS14068.1 FBLN1 gene_id:2192|Hs108|chr22 ( 601) 504 73.2 1.2e-12 CCDS14069.1 FBLN1 gene_id:2192|Hs108|chr22 ( 683) 504 73.3 1.3e-12 CCDS14067.1 FBLN1 gene_id:2192|Hs108|chr22 ( 703) 504 73.3 1.3e-12 CCDS12196.1 FBN3 gene_id:84467|Hs108|chr19 (2809) 506 74.2 2.7e-12 CCDS30956.1 HMCN1 gene_id:83872|Hs108|chr1 (5635) 511 75.2 2.8e-12 CCDS41237.1 MEGF6 gene_id:1953|Hs108|chr1 (1541) 486 71.5 9.6e-12 CCDS55265.1 MATN2 gene_id:4147|Hs108|chr8 ( 937) 466 68.9 3.6e-11 CCDS55264.1 MATN2 gene_id:4147|Hs108|chr8 ( 956) 466 68.9 3.7e-11 CCDS9898.1 FBLN5 gene_id:10516|Hs108|chr14 ( 448) 455 67.2 5.5e-11 CCDS34222.1 FBN2 gene_id:2201|Hs108|chr5 (2912) 469 69.8 5.9e-11 CCDS1857.1 EFEMP1 gene_id:2202|Hs108|chr2 ( 493) 455 67.3 5.9e-11 CCDS83309.1 MATN2 gene_id:4147|Hs108|chr8 ( 915) 459 68.1 6.3e-11 CCDS14048.1 SCUBE1 gene_id:80274|Hs108|chr22 ( 988) 457 67.9 7.8e-11 CCDS46762.1 FBLN2 gene_id:2199|Hs108|chr3 (1184) 458 68.1 8.1e-11 CCDS46761.1 FBLN2 gene_id:2199|Hs108|chr3 (1231) 458 68.1 8.3e-11 >>CCDS13149.1 CD93 gene_id:22918|Hs108|chr20 (652 aa) initn: 4648 init1: 4648 opt: 4648 Z-score: 2999.2 bits: 565.2 E(32554): 9.8e-161 Smith-Waterman score: 4648; 99.8% identity (99.8% similar) in 652 aa overlap (1-652:1-652) 10 20 30 40 50 60 pF1KE0 MATSMGLLLLLLLLLTQPGAGTGADTEAVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MATSMGLLLLLLLLLTQPGAGTGADTEAVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ATVKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 ATVKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 EDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 KFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 KFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFLC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 KEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 ASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 ASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 TPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 TPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 DGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 DGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 PDEEDKGEKEGSTVPRAATASPTRGPEGTLKATPTTSRPSLSSDAPITSAPLKMLAPSGS ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: CCDS13 PDEEDKGEKEGSTVPRAATASPTRGPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 PGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLLLFYILGTVVAILLLLALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLLLFYILGTVVAILLLLALA 550 560 570 580 590 600 610 620 630 640 650 pF1KE0 LGLLVYRKRRAKREEKKEKKPQNAADSYSWVPERAESRAMENQYSPTPGTDC :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LGLLVYRKRRAKREEKKEKKPQNAADSYSWVPERAESRAMENQYSPTPGTDC 610 620 630 640 650 >>CCDS74370.1 LTBP4 gene_id:8425|Hs108|chr19 (1557 aa) initn: 260 init1: 260 opt: 549 Z-score: 364.7 bits: 79.0 E(32554): 5.4e-14 Smith-Waterman score: 566; 33.2% identity (51.1% similar) in 407 aa overlap (107-467:457-851) 80 90 100 110 120 130 pF1KE0 AQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGF-SWVGG--GEDTPYSNWHKELR : ::: .. .:.: :. : :. .. CCDS74 LPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNP 430 440 450 460 470 480 140 150 160 170 pF1KE0 NSCISKRCVS------LLLDLSQPLLP--SRLPKWSE-----GPCGSPG----SPGSNIE . : ::.: : . : : .: .: :: .:: :::: CCDS74 QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGS--F 490 500 510 520 530 540 180 190 200 210 220 pF1KE0 GFVCKFSFKGMCRPLALGGPGQVTYTTP-------FQTTSSSLEAVPFA-SAANVACGEG :: .:.. : . . : .: .: : . : . .:: . . CCDS74 RCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ 550 560 570 580 590 600 230 240 250 260 270 280 pF1KE0 DKDETQSHYFLCKEKA----PDVF----DWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGD : :: . :: . : : : : : : : . : .. CCDS74 DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTA 610 620 630 640 650 660 290 300 310 320 330 pF1KE0 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDS ::: :.: ::: . : . . :. :: : : : . .: .. : ::.:.: .. CCDS74 GSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCE-NTEG-SFQCVCPMGFQPNT 670 680 690 700 710 720 340 350 360 370 380 390 pF1KE0 SQLDCVDVDECQDS-PC-AQECVNTPGGFRCE-CWVGYEPGGPGEGACQDVDECALGRSP . .: :::::.. : .:::::.::.:.:. : :.. .: : :::::. : : CCDS74 AGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLH---RGRCTDVDECSSGAPP 730 740 750 760 770 400 410 420 430 440 450 pF1KE0 CA-QG-CTNTDGSFHCSCEEGY-VLAGEDGTQCQDVDECVGPGGPLC--DSLCFNTQGSF :. .: ::::.:::.::: :: . .:. : : ::.::. : .: . :.::.::: CCDS74 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADVNECLE--GDFCFPHGECLNTDGSF 780 790 800 810 820 830 460 470 480 490 500 510 pF1KE0 HCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTL : : ::. .: :.:: CCDS74 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD 840 850 860 870 880 890 >-- initn: 211 init1: 185 opt: 510 Z-score: 339.7 bits: 74.4 E(32554): 1.3e-12 Smith-Waterman score: 510; 37.0% identity (54.0% similar) in 289 aa overlap (271-541:863-1123) 250 260 270 280 290 300 pF1KE0 KEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC :.. . :::: : : :: : ::..: CCDS74 SFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC 840 850 860 870 880 890 310 320 330 340 350 pF1KE0 ASRNPCSS-SP--CRGGATCVLGPHGKNYTC--RCPQGYQLDSSQLDCVDVDECQD-SP- . . : .: : :. : .: .: : : ::. . . : ::::::. .: CCDS74 LDVDECRERGPALC-GSQRCENSPG--SYRCVRDCDPGYHA-GPEGTCDDVDECQEYGPE 900 910 920 930 940 360 370 380 390 400 pF1KE0 -C-AQECVNTPGGFRCE--CWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSF : ::.: ::::..:: : ::.: :: :.::::::: .:: :. : : ::: CCDS74 ICGAQRCENTPGSYRCTPACDPGYQPT-PG-GGCQDVDECR-NRSFCGAHAVCQNLPGSF 950 960 970 980 990 1000 410 420 430 440 450 460 pF1KE0 HCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC .: :..:: : .:: .: ::.:: : .:: :..::: : : ::. CCDS74 QCLCDQGYEGA-RDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC-------PNS--- 1010 1020 1030 1040 1050 470 480 490 500 510 520 pF1KE0 TMGPVSLGPPSG---PPDEEDKGEKEGSTVPRAATAS--PTRGPEGTLKATPTTSRPSLS : . : .: :: . . : :: :.: .. :.: : : ::: CCDS74 ---PEEFDPMTGRCVPP-RTSAGTFPGSQ-PQAPASPVLPARPPP-----PPLPRRPSTP 1060 1070 1080 1090 1100 530 540 550 560 570 580 pF1KE0 SDAPITSAPLKMLAPSGSPGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLL ..:. :. . ...: CCDS74 RQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEY 1110 1120 1130 1140 1150 1160 >>CCDS74368.1 LTBP4 gene_id:8425|Hs108|chr19 (1587 aa) initn: 260 init1: 260 opt: 549 Z-score: 364.6 bits: 79.0 E(32554): 5.5e-14 Smith-Waterman score: 566; 33.2% identity (51.1% similar) in 407 aa overlap (107-467:487-881) 80 90 100 110 120 130 pF1KE0 AQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGF-SWVGG--GEDTPYSNWHKELR : ::: .. .:.: :. : :. .. CCDS74 LPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNP 460 470 480 490 500 510 140 150 160 170 pF1KE0 NSCISKRCVS------LLLDLSQPLLP--SRLPKWSE-----GPCGSPG----SPGSNIE . : ::.: : . : : .: .: :: .:: :::: CCDS74 QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGS--F 520 530 540 550 560 570 180 190 200 210 220 pF1KE0 GFVCKFSFKGMCRPLALGGPGQVTYTTP-------FQTTSSSLEAVPFA-SAANVACGEG :: .:.. : . . : .: .: : . : . .:: . . CCDS74 RCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ 580 590 600 610 620 630 230 240 250 260 270 280 pF1KE0 DKDETQSHYFLCKEKA----PDVF----DWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGD : :: . :: . : : : : : : : . : .. CCDS74 DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTA 640 650 660 670 680 690 290 300 310 320 330 pF1KE0 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDS ::: :.: ::: . : . . :. :: : : : . .: .. : ::.:.: .. CCDS74 GSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCE-NTEG-SFQCVCPMGFQPNT 700 710 720 730 740 750 340 350 360 370 380 390 pF1KE0 SQLDCVDVDECQDS-PC-AQECVNTPGGFRCE-CWVGYEPGGPGEGACQDVDECALGRSP . .: :::::.. : .:::::.::.:.:. : :.. .: : :::::. : : CCDS74 AGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLH---RGRCTDVDECSSGAPP 760 770 780 790 800 400 410 420 430 440 450 pF1KE0 CA-QG-CTNTDGSFHCSCEEGY-VLAGEDGTQCQDVDECVGPGGPLC--DSLCFNTQGSF :. .: ::::.:::.::: :: . .:. : : ::.::. : .: . :.::.::: CCDS74 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADVNECLE--GDFCFPHGECLNTDGSF 810 820 830 840 850 860 460 470 480 490 500 510 pF1KE0 HCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTL : : ::. .: :.:: CCDS74 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD 870 880 890 900 910 920 >-- initn: 211 init1: 185 opt: 510 Z-score: 339.6 bits: 74.4 E(32554): 1.4e-12 Smith-Waterman score: 510; 37.0% identity (54.0% similar) in 289 aa overlap (271-541:893-1153) 250 260 270 280 290 300 pF1KE0 KEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC :.. . :::: : : :: : ::..: CCDS74 SFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC 870 880 890 900 910 920 310 320 330 340 350 pF1KE0 ASRNPCSS-SP--CRGGATCVLGPHGKNYTC--RCPQGYQLDSSQLDCVDVDECQD-SP- . . : .: : :. : .: .: : : ::. . . : ::::::. .: CCDS74 LDVDECRERGPALC-GSQRCENSPG--SYRCVRDCDPGYHA-GPEGTCDDVDECQEYGPE 930 940 950 960 970 360 370 380 390 400 pF1KE0 -C-AQECVNTPGGFRCE--CWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSF : ::.: ::::..:: : ::.: :: :.::::::: .:: :. : : ::: CCDS74 ICGAQRCENTPGSYRCTPACDPGYQPT-PG-GGCQDVDECR-NRSFCGAHAVCQNLPGSF 980 990 1000 1010 1020 1030 410 420 430 440 450 460 pF1KE0 HCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC .: :..:: : .:: .: ::.:: : .:: :..::: : : ::. CCDS74 QCLCDQGYEGA-RDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC-------PNS--- 1040 1050 1060 1070 1080 470 480 490 500 510 520 pF1KE0 TMGPVSLGPPSG---PPDEEDKGEKEGSTVPRAATAS--PTRGPEGTLKATPTTSRPSLS : . : .: :: . . : :: :.: .. :.: : : ::: CCDS74 ---PEEFDPMTGRCVPP-RTSAGTFPGSQ-PQAPASPVLPARPPP-----PPLPRRPSTP 1090 1100 1110 1120 1130 530 540 550 560 570 580 pF1KE0 SDAPITSAPLKMLAPSGSPGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLL ..:. :. . ...: CCDS74 RQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEY 1140 1150 1160 1170 1180 1190 >>CCDS74369.1 LTBP4 gene_id:8425|Hs108|chr19 (1624 aa) initn: 260 init1: 260 opt: 549 Z-score: 364.5 bits: 79.0 E(32554): 5.6e-14 Smith-Waterman score: 566; 33.2% identity (51.1% similar) in 407 aa overlap (107-467:524-918) 80 90 100 110 120 130 pF1KE0 AQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGF-SWVGG--GEDTPYSNWHKELR : ::: .. .:.: :. : :. .. CCDS74 LPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNP 500 510 520 530 540 550 140 150 160 170 pF1KE0 NSCISKRCVS------LLLDLSQPLLP--SRLPKWSE-----GPCGSPG----SPGSNIE . : ::.: : . : : .: .: :: .:: :::: CCDS74 QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGS--F 560 570 580 590 600 610 180 190 200 210 220 pF1KE0 GFVCKFSFKGMCRPLALGGPGQVTYTTP-------FQTTSSSLEAVPFA-SAANVACGEG :: .:.. : . . : .: .: : . : . .:: . . CCDS74 RCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ 620 630 640 650 660 670 230 240 250 260 270 280 pF1KE0 DKDETQSHYFLCKEKA----PDVF----DWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGD : :: . :: . : : : : : : : . : .. CCDS74 DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTA 680 690 700 710 720 730 290 300 310 320 330 pF1KE0 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDS ::: :.: ::: . : . . :. :: : : : . .: .. : ::.:.: .. CCDS74 GSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCE-NTEG-SFQCVCPMGFQPNT 740 750 760 770 780 340 350 360 370 380 390 pF1KE0 SQLDCVDVDECQDS-PC-AQECVNTPGGFRCE-CWVGYEPGGPGEGACQDVDECALGRSP . .: :::::.. : .:::::.::.:.:. : :.. .: : :::::. : : CCDS74 AGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLH---RGRCTDVDECSSGAPP 790 800 810 820 830 840 400 410 420 430 440 450 pF1KE0 CA-QG-CTNTDGSFHCSCEEGY-VLAGEDGTQCQDVDECVGPGGPLC--DSLCFNTQGSF :. .: ::::.:::.::: :: . .:. : : ::.::. : .: . :.::.::: CCDS74 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADVNECLE--GDFCFPHGECLNTDGSF 850 860 870 880 890 900 460 470 480 490 500 510 pF1KE0 HCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTL : : ::. .: :.:: CCDS74 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD 910 920 930 940 950 960 >-- initn: 211 init1: 185 opt: 510 Z-score: 339.5 bits: 74.4 E(32554): 1.4e-12 Smith-Waterman score: 510; 37.0% identity (54.0% similar) in 289 aa overlap (271-541:930-1190) 250 260 270 280 290 300 pF1KE0 KEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC :.. . :::: : : :: : ::..: CCDS74 SFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC 900 910 920 930 940 950 310 320 330 340 350 pF1KE0 ASRNPCSS-SP--CRGGATCVLGPHGKNYTC--RCPQGYQLDSSQLDCVDVDECQD-SP- . . : .: : :. : .: .: : : ::. . . : ::::::. .: CCDS74 LDVDECRERGPALC-GSQRCENSPG--SYRCVRDCDPGYHA-GPEGTCDDVDECQEYGPE 960 970 980 990 1000 1010 360 370 380 390 400 pF1KE0 -C-AQECVNTPGGFRCE--CWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSF : ::.: ::::..:: : ::.: :: :.::::::: .:: :. : : ::: CCDS74 ICGAQRCENTPGSYRCTPACDPGYQPT-PG-GGCQDVDECR-NRSFCGAHAVCQNLPGSF 1020 1030 1040 1050 1060 1070 410 420 430 440 450 460 pF1KE0 HCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC .: :..:: : .:: .: ::.:: : .:: :..::: : : ::. CCDS74 QCLCDQGYEGA-RDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC-------PNS--- 1080 1090 1100 1110 1120 470 480 490 500 510 520 pF1KE0 TMGPVSLGPPSG---PPDEEDKGEKEGSTVPRAATAS--PTRGPEGTLKATPTTSRPSLS : . : .: :: . . : :: :.: .. :.: : : ::: CCDS74 ---PEEFDPMTGRCVPP-RTSAGTFPGSQ-PQAPASPVLPARPPP-----PPLPRRPSTP 1130 1140 1150 1160 1170 530 540 550 560 570 580 pF1KE0 SDAPITSAPLKMLAPSGSPGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLL ..:. :. . ...: CCDS74 RQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEY 1180 1190 1200 1210 1220 1230 >>CCDS54345.1 LTBP1 gene_id:4052|Hs108|chr2 (1342 aa) initn: 491 init1: 201 opt: 540 Z-score: 359.7 bits: 77.9 E(32554): 1e-13 Smith-Waterman score: 548; 37.6% identity (58.4% similar) in 245 aa overlap (245-467:630-863) 220 230 240 250 260 270 pF1KE0 VPFASAANVACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPL-CVSPKYGCNFNNGGCHQ :: .: : :: : :: : . CCDS54 FRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLD 600 610 620 630 640 650 280 290 300 310 320 pF1KE0 --DCFE-----GGD-----GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGP .:.: .:: ::..:.:. :. : : . . :.. : :: : CCDS54 VDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQ-----GNLCVNG- 660 670 680 690 700 710 330 340 350 360 370 pF1KE0 HGKN----YTCRCPQGYQLDSSQLDCVDVDECQDSP-CAQ-ECVNTPGGFRCECWVGYEP . :: . : : :::::.... .: :.:::: ::. .: :: :.:.: : ::. CCDS54 QCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRA 720 730 740 750 760 770 380 390 400 410 420 430 pF1KE0 GGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGP .: :. :.:..:: .: : .: : :: ::. :.: .:. : .:. :::..:: : CCDS54 SGLGDH-CEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL--DDNKTCQDINECEHP 780 790 800 810 820 830 440 450 460 470 480 490 pF1KE0 GGPLC--DSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGS : :: .. :.::.::::: : :. .. .: .: CCDS54 G--LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSF 840 850 860 870 880 500 510 520 530 540 550 pF1KE0 TVPRAATASPTRGPEGTLKATPTTSRPSLSSDAPITSAPLKMLAPSGSPGVWREPSIHHA CCDS54 RCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQC 890 900 910 920 930 940 >>CCDS54344.1 LTBP1 gene_id:4052|Hs108|chr2 (1353 aa) initn: 308 init1: 228 opt: 540 Z-score: 359.6 bits: 77.9 E(32554): 1e-13 Smith-Waterman score: 548; 37.6% identity (58.4% similar) in 245 aa overlap (245-467:683-916) 220 230 240 250 260 270 pF1KE0 VPFASAANVACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPL-CVSPKYGCNFNNGGCHQ :: .: : :: : :: : . CCDS54 FRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLD 660 670 680 690 700 710 280 290 300 310 320 pF1KE0 --DCFE-----GGD-----GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGP .:.: .:: ::..:.:. :. : : . . :.. : :: : CCDS54 VDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQ-----GNLCVNG- 720 730 740 750 760 330 340 350 360 370 pF1KE0 HGKN----YTCRCPQGYQLDSSQLDCVDVDECQDSP-CAQ-ECVNTPGGFRCECWVGYEP . :: . : : :::::.... .: :.:::: ::. .: :: :.:.: : ::. CCDS54 QCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRA 770 780 790 800 810 820 380 390 400 410 420 430 pF1KE0 GGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGP .: :. :.:..:: .: : .: : :: ::. :.: .:. : .:. :::..:: : CCDS54 SGLGDH-CEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL--DDNKTCQDINECEHP 830 840 850 860 870 880 440 450 460 470 480 490 pF1KE0 GGPLC--DSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGS : :: .. :.::.::::: : :. .. .: .: CCDS54 G--LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDVNECELLSGVCGEAFCENVEGSF 890 900 910 920 930 940 500 510 520 530 540 550 pF1KE0 TVPRAATASPTRGPEGTLKATPTTSRPSLSSDAPITSAPLKMLAPSGSPGVWREPSIHHA CCDS54 LCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTK 950 960 970 980 990 1000 >>CCDS33178.2 LTBP1 gene_id:4052|Hs108|chr2 (1395 aa) initn: 491 init1: 201 opt: 540 Z-score: 359.5 bits: 77.9 E(32554): 1.1e-13 Smith-Waterman score: 548; 37.6% identity (58.4% similar) in 245 aa overlap (245-467:683-916) 220 230 240 250 260 270 pF1KE0 VPFASAANVACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPL-CVSPKYGCNFNNGGCHQ :: .: : :: : :: : . CCDS33 FRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLD 660 670 680 690 700 710 280 290 300 310 320 pF1KE0 --DCFE-----GGD-----GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGP .:.: .:: ::..:.:. :. : : . . :.. : :: : CCDS33 VDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQ-----GNLCVNG- 720 730 740 750 760 330 340 350 360 370 pF1KE0 HGKN----YTCRCPQGYQLDSSQLDCVDVDECQDSP-CAQ-ECVNTPGGFRCECWVGYEP . :: . : : :::::.... .: :.:::: ::. .: :: :.:.: : ::. CCDS33 QCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRA 770 780 790 800 810 820 380 390 400 410 420 430 pF1KE0 GGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGP .: :. :.:..:: .: : .: : :: ::. :.: .:. : .:. :::..:: : CCDS33 SGLGDH-CEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL--DDNKTCQDINECEHP 830 840 850 860 870 880 440 450 460 470 480 490 pF1KE0 GGPLC--DSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGS : :: .. :.::.::::: : :. .. .: .: CCDS33 G--LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSF 890 900 910 920 930 940 500 510 520 530 540 550 pF1KE0 TVPRAATASPTRGPEGTLKATPTTSRPSLSSDAPITSAPLKMLAPSGSPGVWREPSIHHA CCDS33 RCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQC 950 960 970 980 990 1000 >>CCDS33177.2 LTBP1 gene_id:4052|Hs108|chr2 (1721 aa) initn: 491 init1: 201 opt: 540 Z-score: 358.4 bits: 78.0 E(32554): 1.2e-13 Smith-Waterman score: 548; 37.6% identity (58.4% similar) in 245 aa overlap (245-467:1009-1242) 220 230 240 250 260 270 pF1KE0 VPFASAANVACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPL-CVSPKYGCNFNNGGCHQ :: .: : :: : :: : . CCDS33 FRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLD 980 990 1000 1010 1020 1030 280 290 300 310 320 pF1KE0 --DCFE-----GGD-----GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGP .:.: .:: ::..:.:. :. : : . . :.. : :: : CCDS33 VDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQ-----GNLCVNG- 1040 1050 1060 1070 1080 1090 330 340 350 360 370 pF1KE0 HGKN----YTCRCPQGYQLDSSQLDCVDVDECQDSP-CAQ-ECVNTPGGFRCECWVGYEP . :: . : : :::::.... .: :.:::: ::. .: :: :.:.: : ::. CCDS33 QCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRA 1100 1110 1120 1130 1140 1150 380 390 400 410 420 430 pF1KE0 GGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGP .: :. :.:..:: .: : .: : :: ::. :.: .:. : .:. :::..:: : CCDS33 SGLGDH-CEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL--DDNKTCQDINECEHP 1160 1170 1180 1190 1200 440 450 460 470 480 490 pF1KE0 GGPLC--DSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGS : :: .. :.::.::::: : :. .. .: .: CCDS33 G--LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSF 1210 1220 1230 1240 1250 1260 500 510 520 530 540 550 pF1KE0 TVPRAATASPTRGPEGTLKATPTTSRPSLSSDAPITSAPLKMLAPSGSPGVWREPSIHHA CCDS33 RCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQC 1270 1280 1290 1300 1310 1320 >>CCDS8103.1 LTBP3 gene_id:4054|Hs108|chr11 (1256 aa) initn: 483 init1: 142 opt: 537 Z-score: 358.1 bits: 77.5 E(32554): 1.3e-13 Smith-Waterman score: 544; 37.7% identity (55.3% similar) in 284 aa overlap (196-467:569-824) 170 180 190 200 210 220 pF1KE0 GSPGSPGSNIEGFVCKFSFKGMCRPLALGGPGQVTYTTPF---QTTSSSLEAVPFASAAN : ::: : :. . : :: . CCDS81 YPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYS 540 550 560 570 580 590 230 240 250 260 270 280 pF1KE0 VACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGS :. : ... : .: : :: . . : : .: : .:.: :: CCDS81 CHCNPGYRSHPQHRY--CV----DV-NECEAEP-C-GPGRGICMNTG-----------GS 600 610 620 630 290 300 310 320 330 pF1KE0 FLCGCRPGFRLLDDL--VTCASRNPCSSSP-CRGGATCVLGPHGKNYTCRCPQGYQLDSS . : : :.:: .:.. : :.. : :. :. : .: : : ::.: .: CCDS81 YNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPG--HYKCNCYPGYRLKAS 640 650 660 670 680 690 340 350 360 370 380 390 pF1KE0 QLD-CVDVDECQD-SPCAQ-ECVNTPGGFRC-ECWVGYEPGGPGEGACQDVDECALGRSP . : :.:::.: : : . .: : ::.:.: : ::. . : :::.::.::: : :: CCDS81 RPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYR--SQGGGACRDVNECAEG-SP 700 710 720 730 740 750 400 410 420 430 440 450 pF1KE0 CAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS-LCFNTQGSFHCG :. : : : :::.:.: .::. : :: .: ::::: .: .::. .: :: :::.: CCDS81 CSPGWCENLPGSFRCTCAQGYAPA-PDGRSCLDVDEC--EAGDVCDNGICSNTPGSFQCQ 760 770 780 790 800 810 460 470 480 490 500 510 pF1KE0 CLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTLKAT :: :. :. . : CCDS81 CLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDEC 820 830 840 850 860 870 >>CCDS44647.1 LTBP3 gene_id:4054|Hs108|chr11 (1303 aa) initn: 483 init1: 142 opt: 537 Z-score: 357.9 bits: 77.5 E(32554): 1.3e-13 Smith-Waterman score: 544; 37.7% identity (55.3% similar) in 284 aa overlap (196-467:569-824) 170 180 190 200 210 220 pF1KE0 GSPGSPGSNIEGFVCKFSFKGMCRPLALGGPGQVTYTTPF---QTTSSSLEAVPFASAAN : ::: : :. . : :: . CCDS44 YPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYS 540 550 560 570 580 590 230 240 250 260 270 280 pF1KE0 VACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGS :. : ... : .: : :: . . : : .: : .:.: :: CCDS44 CHCNPGYRSHPQHRY--CV----DV-NECEAEP-C-GPGRGICMNTG-----------GS 600 610 620 630 290 300 310 320 330 pF1KE0 FLCGCRPGFRLLDDL--VTCASRNPCSSSP-CRGGATCVLGPHGKNYTCRCPQGYQLDSS . : : :.:: .:.. : :.. : :. :. : .: : : ::.: .: CCDS44 YNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPG--HYKCNCYPGYRLKAS 640 650 660 670 680 690 340 350 360 370 380 390 pF1KE0 QLD-CVDVDECQD-SPCAQ-ECVNTPGGFRC-ECWVGYEPGGPGEGACQDVDECALGRSP . : :.:::.: : : . .: : ::.:.: : ::. . : :::.::.::: : :: CCDS44 RPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYR--SQGGGACRDVNECAEG-SP 700 710 720 730 740 750 400 410 420 430 440 450 pF1KE0 CAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS-LCFNTQGSFHCG :. : : : :::.:.: .::. : :: .: ::::: .: .::. .: :: :::.: CCDS44 CSPGWCENLPGSFRCTCAQGYAPA-PDGRSCLDVDEC--EAGDVCDNGICSNTPGSFQCQ 760 770 780 790 800 810 460 470 480 490 500 510 pF1KE0 CLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTLKAT :: :. :. . : CCDS44 CLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDEC 820 830 840 850 860 870 652 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 16:28:32 2016 done: Thu Nov 3 16:28:33 2016 Total Scan time: 4.490 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]