FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0321, 886 aa 1>>>pF1KE0321 886 - 886 aa - 886 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.4367+/-0.000352; mu= 2.3881+/- 0.022 mean_var=233.0026+/-47.415, 0's: 0 Z-trim(121.5): 58 B-trim: 0 in 0/59 Lambda= 0.084022 statistics sampled from 38130 (38195) to 38130 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.754), E-opt: 0.2 (0.448), width: 16 Scan time: 16.190 The best scores are: opt bits E(85289) XP_011531313 (OMIM: 615900,617023) PREDICTED: cyto ( 886) 6102 753.2 1.2e-216 XP_011531315 (OMIM: 615900,617023) PREDICTED: cyto ( 886) 6102 753.2 1.2e-216 XP_011531314 (OMIM: 615900,617023) PREDICTED: cyto ( 886) 6102 753.2 1.2e-216 NP_068603 (OMIM: 615900,617023) cytosolic carboxyp ( 886) 6102 753.2 1.2e-216 XP_005264534 (OMIM: 615900,617023) PREDICTED: cyto ( 805) 5386 666.4 1.5e-190 NP_001030584 (OMIM: 615900,617023) cytosolic carbo ( 717) 4767 591.3 5.4e-168 XP_011540610 (OMIM: 616476) PREDICTED: cytosolic c ( 531) 438 66.5 3.9e-10 XP_011516722 (OMIM: 606830) PREDICTED: cytosolic c ( 871) 414 63.7 4.4e-09 XP_016870038 (OMIM: 606830) PREDICTED: cytosolic c ( 917) 414 63.7 4.6e-09 XP_016870037 (OMIM: 606830) PREDICTED: cytosolic c ( 961) 414 63.7 4.7e-09 XP_016870036 (OMIM: 606830) PREDICTED: cytosolic c (1064) 414 63.8 5.1e-09 XP_016870035 (OMIM: 606830) PREDICTED: cytosolic c (1068) 414 63.8 5.2e-09 XP_005251906 (OMIM: 606830) PREDICTED: cytosolic c (1108) 414 63.8 5.3e-09 XP_016870034 (OMIM: 606830) PREDICTED: cytosolic c (1142) 414 63.8 5.4e-09 XP_011516720 (OMIM: 606830) PREDICTED: cytosolic c (1182) 414 63.8 5.6e-09 NP_056054 (OMIM: 606830) cytosolic carboxypeptidas (1186) 414 63.8 5.6e-09 XP_005251905 (OMIM: 606830) PREDICTED: cytosolic c (1226) 414 63.8 5.8e-09 XP_016870033 (OMIM: 606830) PREDICTED: cytosolic c (1226) 414 63.8 5.8e-09 NP_001317630 (OMIM: 606830) cytosolic carboxypepti (1226) 414 63.8 5.8e-09 NP_001273646 (OMIM: 606830) cytosolic carboxypepti (1238) 414 63.8 5.8e-09 NP_001273644 (OMIM: 606830) cytosolic carboxypepti (1278) 414 63.8 6e-09 XP_011519529 (OMIM: 615496,615523) PREDICTED: cyto (1057) 384 60.1 6.4e-08 XP_016877408 (OMIM: 615496,615523) PREDICTED: cyto (1093) 384 60.1 6.5e-08 XP_016877407 (OMIM: 615496,615523) PREDICTED: cyto (1110) 384 60.1 6.6e-08 NP_689549 (OMIM: 615496,615523) cytosolic carboxyp (1112) 384 60.1 6.6e-08 XP_011519528 (OMIM: 615496,615523) PREDICTED: cyto (1121) 384 60.1 6.7e-08 XP_016858086 (OMIM: 616476) PREDICTED: cytosolic c ( 464) 319 52.0 7.8e-06 XP_016858085 (OMIM: 616476) PREDICTED: cytosolic c ( 490) 319 52.0 8.1e-06 XP_016858084 (OMIM: 616476) PREDICTED: cytosolic c ( 491) 319 52.0 8.2e-06 NP_001310504 (OMIM: 616476) cytosolic carboxypepti ( 494) 319 52.0 8.2e-06 NP_116174 (OMIM: 616476) cytosolic carboxypeptidas ( 503) 319 52.0 8.3e-06 NP_001310502 (OMIM: 616476) cytosolic carboxypepti ( 506) 319 52.0 8.4e-06 NP_001310503 (OMIM: 616476) cytosolic carboxypepti ( 515) 319 52.0 8.5e-06 XP_016877409 (OMIM: 615496,615523) PREDICTED: cyto ( 862) 279 47.3 0.00037 XP_016858087 (OMIM: 616476) PREDICTED: cytosolic c ( 258) 245 42.9 0.0025 >>XP_011531313 (OMIM: 615900,617023) PREDICTED: cytosoli (886 aa) initn: 6102 init1: 6102 opt: 6102 Z-score: 4010.3 bits: 753.2 E(85289): 1.2e-216 Smith-Waterman score: 6102; 99.9% identity (99.9% similar) in 886 aa overlap (1-886:1-886) 10 20 30 40 50 60 pF1KE0 MELRCGGLLFSSRFDSGNLAHVEKVESLSSDGEGVGGGASALTSGIASSPDYESNVWTRP ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: XP_011 MELRCGGLLFSSRFDSGNLAHVEKVESLSSDGEGVGGGASALTSGIASSPDYEFNVWTRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DCAETEFENGNRSWFYFSVRGGMPGKLIKINIMNMNKQSKLYSQGMAPFVRTLPTRPRWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DCAETEFENGNRSWFYFSVRGGMPGKLIKINIMNMNKQSKLYSQGMAPFVRTLPTRPRWE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RIRDRPTFEMTETQFVLSFVHRFVEGRGATTFFAFCYPFSYSDCQELLNQLDQRFPENHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RIRDRPTFEMTETQFVLSFVHRFVEGRGATTFFAFCYPFSYSDCQELLNQLDQRFPENHP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 THSSPLDTIYYHRELLCYSLDGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPFRFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THSSPLDTIYYHRELLCYSLDGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPFRFA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GKRIFFLSSRVHPGETPSSFVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKRIFFLSSRVHPGETPSSFVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 HYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPSSCLPPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPSSCLPPDA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 PVSDLEKANNLQNEAQCGHSADRHNAEAWKQTEPAEQKLNSVWIMPQQSAGLEESAPDTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVSDLEKANNLQNEAQCGHSADRHNAEAWKQTEPAEQKLNSVWIMPQQSAGLEESAPDTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 PPKESGVAYYVDLHGHASKRGCFMYGNSFSDESTQVENMLYPKLISLNSAHFDFQGCNFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPKESGVAYYVDLHGHASKRGCFMYGNSFSDESTQVENMLYPKLISLNSAHFDFQGCNFS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 EKNMYARDRRDGQSKEGSGRVAIYKASGIIHSYTLECNYNTGRSVNSIPAACHDNGRASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKNMYARDRRDGQSKEGSGRVAIYKASGIIHSYTLECNYNTGRSVNSIPAACHDNGRASP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 PPPPAFPSRYTVELFEQVGRAMAIAALDMAECNPWPRIVLSEHSSLTNLRAWMLKHVRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPPAFPSRYTVELFEQVGRAMAIAALDMAECNPWPRIVLSEHSSLTNLRAWMLKHVRNS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 RGLSSTLNVGVNKKRGLRTPPKSHNGLPVSCSENTLSRARSFSTGTSAGGSSSSQQNSPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGLSSTLNVGVNKKRGLRTPPKSHNGLPVSCSENTLSRARSFSTGTSAGGSSSSQQNSPQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 MKNSPSFPFHGSRPAGLPGLGSSTQKVTHRVLGPVREPRSQDRRRQQQPLNHRPAGSLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKNSPSFPFHGSRPAGLPGLGSSTQKVTHRVLGPVREPRSQDRRRQQQPLNHRPAGSLAP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 SPAPTSSGPASSHKLGSCLLPDSFNIPGSSCSLLSSGDKPEAVMVIGKGLLGTGARMPCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPAPTSSGPASSHKLGSCLLPDSFNIPGSSCSLLSSGDKPEAVMVIGKGLLGTGARMPCI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 KTRLQARPRLGRGSPPTRRGMKGSSGPTSPTPRTRESSELELGSCSATPGLPQARPPRPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTRLQARPRLGRGSPPTRRGMKGSSGPTSPTPRTRESSELELGSCSATPGLPQARPPRPR 790 800 810 820 830 840 850 860 870 880 pF1KE0 SAPAFSPISCSLSDSPSWNCYSRGPLGQPEVCFVPKSPPLTVSPRV :::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAPAFSPISCSLSDSPSWNCYSRGPLGQPEVCFVPKSPPLTVSPRV 850 860 870 880 >>XP_011531315 (OMIM: 615900,617023) PREDICTED: cytosoli (886 aa) initn: 6102 init1: 6102 opt: 6102 Z-score: 4010.3 bits: 753.2 E(85289): 1.2e-216 Smith-Waterman score: 6102; 99.9% identity (99.9% similar) in 886 aa overlap (1-886:1-886) 10 20 30 40 50 60 pF1KE0 MELRCGGLLFSSRFDSGNLAHVEKVESLSSDGEGVGGGASALTSGIASSPDYESNVWTRP ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: XP_011 MELRCGGLLFSSRFDSGNLAHVEKVESLSSDGEGVGGGASALTSGIASSPDYEFNVWTRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DCAETEFENGNRSWFYFSVRGGMPGKLIKINIMNMNKQSKLYSQGMAPFVRTLPTRPRWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DCAETEFENGNRSWFYFSVRGGMPGKLIKINIMNMNKQSKLYSQGMAPFVRTLPTRPRWE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RIRDRPTFEMTETQFVLSFVHRFVEGRGATTFFAFCYPFSYSDCQELLNQLDQRFPENHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RIRDRPTFEMTETQFVLSFVHRFVEGRGATTFFAFCYPFSYSDCQELLNQLDQRFPENHP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 THSSPLDTIYYHRELLCYSLDGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPFRFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THSSPLDTIYYHRELLCYSLDGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPFRFA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GKRIFFLSSRVHPGETPSSFVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKRIFFLSSRVHPGETPSSFVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 HYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPSSCLPPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPSSCLPPDA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 PVSDLEKANNLQNEAQCGHSADRHNAEAWKQTEPAEQKLNSVWIMPQQSAGLEESAPDTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVSDLEKANNLQNEAQCGHSADRHNAEAWKQTEPAEQKLNSVWIMPQQSAGLEESAPDTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 PPKESGVAYYVDLHGHASKRGCFMYGNSFSDESTQVENMLYPKLISLNSAHFDFQGCNFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPKESGVAYYVDLHGHASKRGCFMYGNSFSDESTQVENMLYPKLISLNSAHFDFQGCNFS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 EKNMYARDRRDGQSKEGSGRVAIYKASGIIHSYTLECNYNTGRSVNSIPAACHDNGRASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKNMYARDRRDGQSKEGSGRVAIYKASGIIHSYTLECNYNTGRSVNSIPAACHDNGRASP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 PPPPAFPSRYTVELFEQVGRAMAIAALDMAECNPWPRIVLSEHSSLTNLRAWMLKHVRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPPAFPSRYTVELFEQVGRAMAIAALDMAECNPWPRIVLSEHSSLTNLRAWMLKHVRNS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 RGLSSTLNVGVNKKRGLRTPPKSHNGLPVSCSENTLSRARSFSTGTSAGGSSSSQQNSPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGLSSTLNVGVNKKRGLRTPPKSHNGLPVSCSENTLSRARSFSTGTSAGGSSSSQQNSPQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 MKNSPSFPFHGSRPAGLPGLGSSTQKVTHRVLGPVREPRSQDRRRQQQPLNHRPAGSLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKNSPSFPFHGSRPAGLPGLGSSTQKVTHRVLGPVREPRSQDRRRQQQPLNHRPAGSLAP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 SPAPTSSGPASSHKLGSCLLPDSFNIPGSSCSLLSSGDKPEAVMVIGKGLLGTGARMPCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPAPTSSGPASSHKLGSCLLPDSFNIPGSSCSLLSSGDKPEAVMVIGKGLLGTGARMPCI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 KTRLQARPRLGRGSPPTRRGMKGSSGPTSPTPRTRESSELELGSCSATPGLPQARPPRPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTRLQARPRLGRGSPPTRRGMKGSSGPTSPTPRTRESSELELGSCSATPGLPQARPPRPR 790 800 810 820 830 840 850 860 870 880 pF1KE0 SAPAFSPISCSLSDSPSWNCYSRGPLGQPEVCFVPKSPPLTVSPRV :::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAPAFSPISCSLSDSPSWNCYSRGPLGQPEVCFVPKSPPLTVSPRV 850 860 870 880 >>XP_011531314 (OMIM: 615900,617023) PREDICTED: cytosoli (886 aa) initn: 6102 init1: 6102 opt: 6102 Z-score: 4010.3 bits: 753.2 E(85289): 1.2e-216 Smith-Waterman score: 6102; 99.9% identity (99.9% similar) in 886 aa overlap (1-886:1-886) 10 20 30 40 50 60 pF1KE0 MELRCGGLLFSSRFDSGNLAHVEKVESLSSDGEGVGGGASALTSGIASSPDYESNVWTRP ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: XP_011 MELRCGGLLFSSRFDSGNLAHVEKVESLSSDGEGVGGGASALTSGIASSPDYEFNVWTRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DCAETEFENGNRSWFYFSVRGGMPGKLIKINIMNMNKQSKLYSQGMAPFVRTLPTRPRWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DCAETEFENGNRSWFYFSVRGGMPGKLIKINIMNMNKQSKLYSQGMAPFVRTLPTRPRWE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RIRDRPTFEMTETQFVLSFVHRFVEGRGATTFFAFCYPFSYSDCQELLNQLDQRFPENHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RIRDRPTFEMTETQFVLSFVHRFVEGRGATTFFAFCYPFSYSDCQELLNQLDQRFPENHP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 THSSPLDTIYYHRELLCYSLDGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPFRFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THSSPLDTIYYHRELLCYSLDGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPFRFA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GKRIFFLSSRVHPGETPSSFVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKRIFFLSSRVHPGETPSSFVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 HYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPSSCLPPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPSSCLPPDA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 PVSDLEKANNLQNEAQCGHSADRHNAEAWKQTEPAEQKLNSVWIMPQQSAGLEESAPDTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVSDLEKANNLQNEAQCGHSADRHNAEAWKQTEPAEQKLNSVWIMPQQSAGLEESAPDTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 PPKESGVAYYVDLHGHASKRGCFMYGNSFSDESTQVENMLYPKLISLNSAHFDFQGCNFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPKESGVAYYVDLHGHASKRGCFMYGNSFSDESTQVENMLYPKLISLNSAHFDFQGCNFS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 EKNMYARDRRDGQSKEGSGRVAIYKASGIIHSYTLECNYNTGRSVNSIPAACHDNGRASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKNMYARDRRDGQSKEGSGRVAIYKASGIIHSYTLECNYNTGRSVNSIPAACHDNGRASP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 PPPPAFPSRYTVELFEQVGRAMAIAALDMAECNPWPRIVLSEHSSLTNLRAWMLKHVRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPPAFPSRYTVELFEQVGRAMAIAALDMAECNPWPRIVLSEHSSLTNLRAWMLKHVRNS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 RGLSSTLNVGVNKKRGLRTPPKSHNGLPVSCSENTLSRARSFSTGTSAGGSSSSQQNSPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGLSSTLNVGVNKKRGLRTPPKSHNGLPVSCSENTLSRARSFSTGTSAGGSSSSQQNSPQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 MKNSPSFPFHGSRPAGLPGLGSSTQKVTHRVLGPVREPRSQDRRRQQQPLNHRPAGSLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKNSPSFPFHGSRPAGLPGLGSSTQKVTHRVLGPVREPRSQDRRRQQQPLNHRPAGSLAP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 SPAPTSSGPASSHKLGSCLLPDSFNIPGSSCSLLSSGDKPEAVMVIGKGLLGTGARMPCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPAPTSSGPASSHKLGSCLLPDSFNIPGSSCSLLSSGDKPEAVMVIGKGLLGTGARMPCI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 KTRLQARPRLGRGSPPTRRGMKGSSGPTSPTPRTRESSELELGSCSATPGLPQARPPRPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTRLQARPRLGRGSPPTRRGMKGSSGPTSPTPRTRESSELELGSCSATPGLPQARPPRPR 790 800 810 820 830 840 850 860 870 880 pF1KE0 SAPAFSPISCSLSDSPSWNCYSRGPLGQPEVCFVPKSPPLTVSPRV :::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAPAFSPISCSLSDSPSWNCYSRGPLGQPEVCFVPKSPPLTVSPRV 850 860 870 880 >>NP_068603 (OMIM: 615900,617023) cytosolic carboxypepti (886 aa) initn: 6102 init1: 6102 opt: 6102 Z-score: 4010.3 bits: 753.2 E(85289): 1.2e-216 Smith-Waterman score: 6102; 99.9% identity (99.9% similar) in 886 aa overlap (1-886:1-886) 10 20 30 40 50 60 pF1KE0 MELRCGGLLFSSRFDSGNLAHVEKVESLSSDGEGVGGGASALTSGIASSPDYESNVWTRP ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: NP_068 MELRCGGLLFSSRFDSGNLAHVEKVESLSSDGEGVGGGASALTSGIASSPDYEFNVWTRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DCAETEFENGNRSWFYFSVRGGMPGKLIKINIMNMNKQSKLYSQGMAPFVRTLPTRPRWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 DCAETEFENGNRSWFYFSVRGGMPGKLIKINIMNMNKQSKLYSQGMAPFVRTLPTRPRWE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RIRDRPTFEMTETQFVLSFVHRFVEGRGATTFFAFCYPFSYSDCQELLNQLDQRFPENHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 RIRDRPTFEMTETQFVLSFVHRFVEGRGATTFFAFCYPFSYSDCQELLNQLDQRFPENHP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 THSSPLDTIYYHRELLCYSLDGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPFRFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 THSSPLDTIYYHRELLCYSLDGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPFRFA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GKRIFFLSSRVHPGETPSSFVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 GKRIFFLSSRVHPGETPSSFVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 HYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPSSCLPPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 HYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPSSCLPPDA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 PVSDLEKANNLQNEAQCGHSADRHNAEAWKQTEPAEQKLNSVWIMPQQSAGLEESAPDTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 PVSDLEKANNLQNEAQCGHSADRHNAEAWKQTEPAEQKLNSVWIMPQQSAGLEESAPDTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 PPKESGVAYYVDLHGHASKRGCFMYGNSFSDESTQVENMLYPKLISLNSAHFDFQGCNFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 PPKESGVAYYVDLHGHASKRGCFMYGNSFSDESTQVENMLYPKLISLNSAHFDFQGCNFS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 EKNMYARDRRDGQSKEGSGRVAIYKASGIIHSYTLECNYNTGRSVNSIPAACHDNGRASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 EKNMYARDRRDGQSKEGSGRVAIYKASGIIHSYTLECNYNTGRSVNSIPAACHDNGRASP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 PPPPAFPSRYTVELFEQVGRAMAIAALDMAECNPWPRIVLSEHSSLTNLRAWMLKHVRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 PPPPAFPSRYTVELFEQVGRAMAIAALDMAECNPWPRIVLSEHSSLTNLRAWMLKHVRNS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 RGLSSTLNVGVNKKRGLRTPPKSHNGLPVSCSENTLSRARSFSTGTSAGGSSSSQQNSPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 RGLSSTLNVGVNKKRGLRTPPKSHNGLPVSCSENTLSRARSFSTGTSAGGSSSSQQNSPQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 MKNSPSFPFHGSRPAGLPGLGSSTQKVTHRVLGPVREPRSQDRRRQQQPLNHRPAGSLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 MKNSPSFPFHGSRPAGLPGLGSSTQKVTHRVLGPVREPRSQDRRRQQQPLNHRPAGSLAP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 SPAPTSSGPASSHKLGSCLLPDSFNIPGSSCSLLSSGDKPEAVMVIGKGLLGTGARMPCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 SPAPTSSGPASSHKLGSCLLPDSFNIPGSSCSLLSSGDKPEAVMVIGKGLLGTGARMPCI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 KTRLQARPRLGRGSPPTRRGMKGSSGPTSPTPRTRESSELELGSCSATPGLPQARPPRPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 KTRLQARPRLGRGSPPTRRGMKGSSGPTSPTPRTRESSELELGSCSATPGLPQARPPRPR 790 800 810 820 830 840 850 860 870 880 pF1KE0 SAPAFSPISCSLSDSPSWNCYSRGPLGQPEVCFVPKSPPLTVSPRV :::::::::::::::::::::::::::::::::::::::::::::: NP_068 SAPAFSPISCSLSDSPSWNCYSRGPLGQPEVCFVPKSPPLTVSPRV 850 860 870 880 >>XP_005264534 (OMIM: 615900,617023) PREDICTED: cytosoli (805 aa) initn: 5383 init1: 5383 opt: 5386 Z-score: 3541.8 bits: 666.4 E(85289): 1.5e-190 Smith-Waterman score: 5386; 98.9% identity (99.1% similar) in 797 aa overlap (1-797:1-793) 10 20 30 40 50 60 pF1KE0 MELRCGGLLFSSRFDSGNLAHVEKVESLSSDGEGVGGGASALTSGIASSPDYESNVWTRP ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: XP_005 MELRCGGLLFSSRFDSGNLAHVEKVESLSSDGEGVGGGASALTSGIASSPDYEFNVWTRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DCAETEFENGNRSWFYFSVRGGMPGKLIKINIMNMNKQSKLYSQGMAPFVRTLPTRPRWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DCAETEFENGNRSWFYFSVRGGMPGKLIKINIMNMNKQSKLYSQGMAPFVRTLPTRPRWE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RIRDRPTFEMTETQFVLSFVHRFVEGRGATTFFAFCYPFSYSDCQELLNQLDQRFPENHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RIRDRPTFEMTETQFVLSFVHRFVEGRGATTFFAFCYPFSYSDCQELLNQLDQRFPENHP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 THSSPLDTIYYHRELLCYSLDGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPFRFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 THSSPLDTIYYHRELLCYSLDGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPFRFA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GKRIFFLSSRVHPGETPSSFVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKRIFFLSSRVHPGETPSSFVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 HYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPSSCLPPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPSSCLPPDA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 PVSDLEKANNLQNEAQCGHSADRHNAEAWKQTEPAEQKLNSVWIMPQQSAGLEESAPDTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVSDLEKANNLQNEAQCGHSADRHNAEAWKQTEPAEQKLNSVWIMPQQSAGLEESAPDTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 PPKESGVAYYVDLHGHASKRGCFMYGNSFSDESTQVENMLYPKLISLNSAHFDFQGCNFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPKESGVAYYVDLHGHASKRGCFMYGNSFSDESTQVENMLYPKLISLNSAHFDFQGCNFS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 EKNMYARDRRDGQSKEGSGRVAIYKASGIIHSYTLECNYNTGRSVNSIPAACHDNGRASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKNMYARDRRDGQSKEGSGRVAIYKASGIIHSYTLECNYNTGRSVNSIPAACHDNGRASP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 PPPPAFPSRYTVELFEQVGRAMAIAALDMAECNPWPRIVLSEHSSLTNLRAWMLKHVRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPPPAFPSRYTVELFEQVGRAMAIAALDMAECNPWPRIVLSEHSSLTNLRAWMLKHVRNS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 RGLSSTLNVGVNKKRGLRTPPKSHNGLPVSCSENTLSRARSFSTGTSAGGSSSSQQNSPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGLSSTLNVGVNKKRGLRTPPKSHNGLPVSCSENTLSRARSFSTGTSAGGSSSSQQNSPQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 MKNSPSFPFHGSRPAGLPGLGSSTQKVTHRVLGPVREPRSQDRRRQQQPLNHRPAGSLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKNSPSFPFHGSRPAGLPGLGSSTQKVTHRVLGPVREPRSQDRRRQQQPLNHRPAGSLAP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 SPAPTSSGPASSHKLGSCLLPDSFNIPGSSCSLLSSGDKPEAVMVIGKGLLGTGARMPCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPAPTSSGPASSHKLGSCLLPDSFNIPGSSCSLLSSGDKPEAVMVIGKGLLGTGARMPCI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 KTRLQARPRLGRGSPPTRRGMKGSSGPTSPTPRTRESSELELGSCSATPGLPQARPPRPR :::::: . :. :: XP_005 KTRLQA----ASGQAPTAPLCPCLFSYIL 790 800 >>NP_001030584 (OMIM: 615900,617023) cytosolic carboxype (717 aa) initn: 4767 init1: 4767 opt: 4767 Z-score: 3137.0 bits: 591.3 E(85289): 5.4e-168 Smith-Waterman score: 4767; 99.9% identity (99.9% similar) in 696 aa overlap (1-696:1-696) 10 20 30 40 50 60 pF1KE0 MELRCGGLLFSSRFDSGNLAHVEKVESLSSDGEGVGGGASALTSGIASSPDYESNVWTRP ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: NP_001 MELRCGGLLFSSRFDSGNLAHVEKVESLSSDGEGVGGGASALTSGIASSPDYEFNVWTRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DCAETEFENGNRSWFYFSVRGGMPGKLIKINIMNMNKQSKLYSQGMAPFVRTLPTRPRWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DCAETEFENGNRSWFYFSVRGGMPGKLIKINIMNMNKQSKLYSQGMAPFVRTLPTRPRWE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RIRDRPTFEMTETQFVLSFVHRFVEGRGATTFFAFCYPFSYSDCQELLNQLDQRFPENHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIRDRPTFEMTETQFVLSFVHRFVEGRGATTFFAFCYPFSYSDCQELLNQLDQRFPENHP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 THSSPLDTIYYHRELLCYSLDGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPFRFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THSSPLDTIYYHRELLCYSLDGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPFRFA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GKRIFFLSSRVHPGETPSSFVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKRIFFLSSRVHPGETPSSFVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 HYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPSSCLPPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPSSCLPPDA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 PVSDLEKANNLQNEAQCGHSADRHNAEAWKQTEPAEQKLNSVWIMPQQSAGLEESAPDTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVSDLEKANNLQNEAQCGHSADRHNAEAWKQTEPAEQKLNSVWIMPQQSAGLEESAPDTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 PPKESGVAYYVDLHGHASKRGCFMYGNSFSDESTQVENMLYPKLISLNSAHFDFQGCNFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPKESGVAYYVDLHGHASKRGCFMYGNSFSDESTQVENMLYPKLISLNSAHFDFQGCNFS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 EKNMYARDRRDGQSKEGSGRVAIYKASGIIHSYTLECNYNTGRSVNSIPAACHDNGRASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKNMYARDRRDGQSKEGSGRVAIYKASGIIHSYTLECNYNTGRSVNSIPAACHDNGRASP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 PPPPAFPSRYTVELFEQVGRAMAIAALDMAECNPWPRIVLSEHSSLTNLRAWMLKHVRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPPAFPSRYTVELFEQVGRAMAIAALDMAECNPWPRIVLSEHSSLTNLRAWMLKHVRNS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 RGLSSTLNVGVNKKRGLRTPPKSHNGLPVSCSENTLSRARSFSTGTSAGGSSSSQQNSPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGLSSTLNVGVNKKRGLRTPPKSHNGLPVSCSENTLSRARSFSTGTSAGGSSSSQQNSPQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 MKNSPSFPFHGSRPAGLPGLGSSTQKVTHRVLGPVREPRSQDRRRQQQPLNHRPAGSLAP :::::::::::::::::::::::::::::::::::: NP_001 MKNSPSFPFHGSRPAGLPGLGSSTQKVTHRVLGPVRGKPVWEPLQHVFGCLGHCWGK 670 680 690 700 710 730 740 750 760 770 780 pF1KE0 SPAPTSSGPASSHKLGSCLLPDSFNIPGSSCSLLSSGDKPEAVMVIGKGLLGTGARMPCI >>XP_011540610 (OMIM: 616476) PREDICTED: cytosolic carbo (531 aa) initn: 564 init1: 197 opt: 438 Z-score: 302.8 bits: 66.5 E(85289): 3.9e-10 Smith-Waterman score: 475; 30.2% identity (54.7% similar) in 371 aa overlap (6-334:42-348) 10 20 30 pF1KE0 MELRCGGLLFSSRFDSGNLAHVEKVESLSSDGEGV : :.:.. :.::::..:..: XP_011 GNDMGNDDAIGGNVSKYIVLPTGYCGQPKKGHLIFDACFESGNLGRVDQVS--------- 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 GGGASALTSGIASSPDYESNVWTRPDCAETEFENGNRSWFYFSVRGGMPGKLIKI----- ..: ... ::: . .: : :: :.:.. ... .: XP_011 ---------------EFEYDLFIRPDTCNPRF----RVWFNFTVENVKESQVREIVDTFR 70 80 90 100 100 110 120 130 pF1KE0 -------NIMNMNKQSKLYSQGMAPFVRTLPTRPRWERIRDRPTFEMT----ETQFVLSF ::.:..: ..:: .::::.:.. .::.:.:. . .. . . ..:.:: XP_011 VVLRVIFNIVNFSKTKSLYRDGMAPMVKST-SRPKWQRLPPKNVYYYRCPDHRKNYVMSF 110 120 130 140 150 160 140 150 160 170 180 190 pF1KE0 VHRFVEGRGATTF-FAFCYPFSYSDCQELLNQLDQRFPENHPTHSSPLDTIYYHRELLCY . : : . ::.:::..:. :. :..:..: .: :. :: : XP_011 A--FCFDREEDIYQFAYCYPYTYTRFQHYLDSLQKR----------NMD--YFFREQLGQ 170 180 190 200 200 210 220 230 240 250 pF1KE0 SLDGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPFRFAGKRIFFLSSRVHPGETPS :.. ..::::::: .::: : ... :...::::::::: XP_011 SVQQRKLDLLTITSPDNLREGAE--------------------QKVVFITGRVHPGETPS 210 220 230 240 260 270 280 290 pF1KE0 SFVFNGF-------------------------LDFILRPDDPRAQTLRRLFVFKLIPMLN ::: .:. .::.. . : : .::. .:::. :::: XP_011 SFVCQGIPPGHWAALSSSFQNSPGIHWMSPGIIDFLVS-QHPIACVLREYLVFKIAPMLN 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE0 PDGVVRGHYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPS :::: :.:: . : .:::..: :. .::...:.: ... XP_011 PDGVYLGNYRCSLMGFDLNRHWLDPSPWVHPTLHGVKQLIVQMYNDPKTSLEFYIDIHAH 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE0 SCLPPDAPVSDLEKANNLQNEAQCGHSADRHNAEAWKQTEPAEQKLNSVWIMPQQSAGLE XP_011 STMMNGFMYGNIFEDEERFQRQAIFPKLLCQNAEDFSYSSTSFNRDAVKAGTGRRFLGGL 370 380 390 400 410 420 >>XP_011516722 (OMIM: 606830) PREDICTED: cytosolic carbo (871 aa) initn: 559 init1: 242 opt: 414 Z-score: 284.1 bits: 63.7 E(85289): 4.4e-09 Smith-Waterman score: 496; 32.4% identity (61.8% similar) in 293 aa overlap (69-342:388-654) 40 50 60 70 80 90 pF1KE0 ASALTSGIASSPDYESNVWTRPDCAETEFENGNRSWFYFSVRGGMPGKLIKINIMNMNKQ : ..:::: : : :: ..::.: .:. XP_011 NSKFESGNLRKVIQIRKNEYDLILNSDINSNHYHQWFYFEVSGMRPGVAYRFNIINCEKS 360 370 380 390 400 410 100 110 120 130 140 pF1KE0 SKLYSQGMAPFVRT----LPTRPRWERI-RD----RPTFEMT---------ETQFVLSFV .. .. :: :.. . : .:: : :. : . : . .. ....:. XP_011 NSQFNYGMQPLMYSVQEALNARPWWIRMGTDICYYKNHFSRSSVAAGGQKGKSYYTITFT 420 430 440 450 460 470 150 160 170 180 190 200 pF1KE0 HRFVEGRGATTFFAFCYPFSYSDCQELLNQLDQRFPENHPTHSSPLDTIYYHRELLCYSL : . . .::. ::..:: : :..:.. ..: . ::.....:: .: XP_011 VNF-PHKDDVCYFAYHYPYTYSTLQMHLQKLES---AHNPQQ------IYFRKDVLCETL 480 490 500 510 520 210 220 230 240 250 pF1KE0 DGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPF-RFAGKRIFFLSSRVHPGETPSS .: :.:::. .:... . . .: .. :::.::::::: .: XP_011 SGNSCPLVTITA---------------MPESNYYEHICHFRNRPYVFLSARVHPGETNAS 530 540 550 560 570 260 270 280 290 300 310 pF1KE0 FVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRGHYRTDSRGVNLNRQYLKPD .:..: :.... ..: ::.::. ..::..::::::::. :..: . : .::::. .:. XP_011 WVMKGTLEYLMS-NNPTAQSLRESYIFKIVPMLNPDGVINGNHRCSLSGEDLNRQWQSPS 580 590 600 610 620 630 320 330 340 350 360 370 pF1KE0 AVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPSSCLPPDAPVSDLEKANNLQNEAQCGH :::.:: ::..: : . .:: XP_011 PDLHPTIYHAKGLLQYLAAVKRLPLVYCDYHGHSRKKNVFMYGCSIKETVWHTNDNATSC 640 650 660 670 680 690 >>XP_016870038 (OMIM: 606830) PREDICTED: cytosolic carbo (917 aa) initn: 559 init1: 242 opt: 414 Z-score: 283.7 bits: 63.7 E(85289): 4.6e-09 Smith-Waterman score: 496; 32.4% identity (61.8% similar) in 293 aa overlap (69-342:478-744) 40 50 60 70 80 90 pF1KE0 ASALTSGIASSPDYESNVWTRPDCAETEFENGNRSWFYFSVRGGMPGKLIKINIMNMNKQ : ..:::: : : :: ..::.: .:. XP_016 NSKFESGNLRKVIQIRKNEYDLILNSDINSNHYHQWFYFEVSGMRPGVAYRFNIINCEKS 450 460 470 480 490 500 100 110 120 130 140 pF1KE0 SKLYSQGMAPFVRT----LPTRPRWERI-RD----RPTFEMT---------ETQFVLSFV .. .. :: :.. . : .:: : :. : . : . .. ....:. XP_016 NSQFNYGMQPLMYSVQEALNARPWWIRMGTDICYYKNHFSRSSVAAGGQKGKSYYTITFT 510 520 530 540 550 560 150 160 170 180 190 200 pF1KE0 HRFVEGRGATTFFAFCYPFSYSDCQELLNQLDQRFPENHPTHSSPLDTIYYHRELLCYSL : . . .::. ::..:: : :..:.. ..: . ::.....:: .: XP_016 VNF-PHKDDVCYFAYHYPYTYSTLQMHLQKLES---AHNPQQ------IYFRKDVLCETL 570 580 590 600 610 210 220 230 240 250 pF1KE0 DGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPF-RFAGKRIFFLSSRVHPGETPSS .: :.:::. .:... . . .: .. :::.::::::: .: XP_016 SGNSCPLVTITA---------------MPESNYYEHICHFRNRPYVFLSARVHPGETNAS 620 630 640 650 660 260 270 280 290 300 310 pF1KE0 FVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRGHYRTDSRGVNLNRQYLKPD .:..: :.... ..: ::.::. ..::..::::::::. :..: . : .::::. .:. XP_016 WVMKGTLEYLMS-NNPTAQSLRESYIFKIVPMLNPDGVINGNHRCSLSGEDLNRQWQSPS 670 680 690 700 710 720 320 330 340 350 360 370 pF1KE0 AVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPSSCLPPDAPVSDLEKANNLQNEAQCGH :::.:: ::..: : . .:: XP_016 PDLHPTIYHAKGLLQYLAAVKRLPLVYCDYHGHSRKKNVFMYGCSIKETVWHTNDNATSC 730 740 750 760 770 780 >>XP_016870037 (OMIM: 606830) PREDICTED: cytosolic carbo (961 aa) initn: 559 init1: 242 opt: 414 Z-score: 283.5 bits: 63.7 E(85289): 4.7e-09 Smith-Waterman score: 496; 32.4% identity (61.8% similar) in 293 aa overlap (69-342:478-744) 40 50 60 70 80 90 pF1KE0 ASALTSGIASSPDYESNVWTRPDCAETEFENGNRSWFYFSVRGGMPGKLIKINIMNMNKQ : ..:::: : : :: ..::.: .:. XP_016 NSKFESGNLRKVIQIRKNEYDLILNSDINSNHYHQWFYFEVSGMRPGVAYRFNIINCEKS 450 460 470 480 490 500 100 110 120 130 140 pF1KE0 SKLYSQGMAPFVRT----LPTRPRWERI-RD----RPTFEMT---------ETQFVLSFV .. .. :: :.. . : .:: : :. : . : . .. ....:. XP_016 NSQFNYGMQPLMYSVQEALNARPWWIRMGTDICYYKNHFSRSSVAAGGQKGKSYYTITFT 510 520 530 540 550 560 150 160 170 180 190 200 pF1KE0 HRFVEGRGATTFFAFCYPFSYSDCQELLNQLDQRFPENHPTHSSPLDTIYYHRELLCYSL : . . .::. ::..:: : :..:.. ..: . ::.....:: .: XP_016 VNF-PHKDDVCYFAYHYPYTYSTLQMHLQKLES---AHNPQQ------IYFRKDVLCETL 570 580 590 600 610 210 220 230 240 250 pF1KE0 DGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPF-RFAGKRIFFLSSRVHPGETPSS .: :.:::. .:... . . .: .. :::.::::::: .: XP_016 SGNSCPLVTITA---------------MPESNYYEHICHFRNRPYVFLSARVHPGETNAS 620 630 640 650 660 260 270 280 290 300 310 pF1KE0 FVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRGHYRTDSRGVNLNRQYLKPD .:..: :.... ..: ::.::. ..::..::::::::. :..: . : .::::. .:. XP_016 WVMKGTLEYLMS-NNPTAQSLRESYIFKIVPMLNPDGVINGNHRCSLSGEDLNRQWQSPS 670 680 690 700 710 720 320 330 340 350 360 370 pF1KE0 AVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPSSCLPPDAPVSDLEKANNLQNEAQCGH :::.:: ::..: : . .:: XP_016 PDLHPTIYHAKGLLQYLAAVKRLPLVYCDYHGHSRKKNVFMYGCSIKETVWHTNDNATSC 730 740 750 760 770 780 886 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 16:04:52 2016 done: Thu Nov 3 16:04:55 2016 Total Scan time: 16.190 Total Display time: 0.240 Function used was FASTA [36.3.4 Apr, 2011]