FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0327, 618 aa 1>>>pF1KE0327 618 - 618 aa - 618 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6715+/-0.000453; mu= 23.1094+/- 0.028 mean_var=74.7054+/-16.098, 0's: 0 Z-trim(110.5): 60 B-trim: 378 in 1/52 Lambda= 0.148388 statistics sampled from 18849 (18893) to 18849 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.567), E-opt: 0.2 (0.222), width: 16 Scan time: 10.560 The best scores are: opt bits E(85289) NP_079016 (OMIM: 263210,606941,608776) alpha-1,2-m ( 618) 4241 918.1 0 XP_005277780 (OMIM: 263210,606941,608776) PREDICTE ( 629) 4233 916.4 0 NP_001071158 (OMIM: 263210,606941,608776) alpha-1, ( 611) 4166 902.0 0 XP_005277781 (OMIM: 263210,606941,608776) PREDICTE ( 622) 4158 900.3 0 XP_011541294 (OMIM: 263210,606941,608776) PREDICTE ( 618) 3992 864.8 0 XP_006718976 (OMIM: 263210,606941,608776) PREDICTE ( 598) 3979 862.0 0 XP_016873802 (OMIM: 263210,606941,608776) PREDICTE ( 611) 3917 848.7 0 XP_016873808 (OMIM: 263210,606941,608776) PREDICTE ( 447) 3074 668.1 1.8e-191 NP_001071159 (OMIM: 263210,606941,608776) alpha-1, ( 447) 3074 668.1 1.8e-191 XP_016873809 (OMIM: 263210,606941,608776) PREDICTE ( 447) 3074 668.1 1.8e-191 XP_016873805 (OMIM: 263210,606941,608776) PREDICTE ( 458) 3066 666.4 5.9e-191 XP_016873811 (OMIM: 263210,606941,608776) PREDICTE ( 440) 2999 652.0 1.2e-186 XP_016873810 (OMIM: 263210,606941,608776) PREDICTE ( 440) 2999 652.0 1.2e-186 NP_001071160 (OMIM: 263210,606941,608776) alpha-1, ( 440) 2999 652.0 1.2e-186 XP_016873806 (OMIM: 263210,606941,608776) PREDICTE ( 451) 2991 650.3 4e-186 XP_016873807 (OMIM: 263210,606941,608776) PREDICTE ( 451) 2991 650.3 4e-186 XP_016873814 (OMIM: 263210,606941,608776) PREDICTE ( 415) 2832 616.3 6.7e-176 XP_016873812 (OMIM: 263210,606941,608776) PREDICTE ( 440) 2750 598.7 1.3e-170 XP_016873813 (OMIM: 263210,606941,608776) PREDICTE ( 420) 2737 595.9 8.9e-170 XP_016873804 (OMIM: 263210,606941,608776) PREDICTE ( 570) 2028 444.3 5.4e-124 XP_016873803 (OMIM: 263210,606941,608776) PREDICTE ( 577) 2028 444.3 5.5e-124 XP_016873815 (OMIM: 263210,606941,608776) PREDICTE ( 399) 1875 411.4 3.1e-114 NP_004846 (OMIM: 604122) GPI mannosyltransferase 3 ( 554) 219 57.0 2e-07 >>NP_079016 (OMIM: 263210,606941,608776) alpha-1,2-manno (618 aa) initn: 4241 init1: 4241 opt: 4241 Z-score: 4907.0 bits: 918.1 E(85289): 0 Smith-Waterman score: 4241; 100.0% identity (100.0% similar) in 618 aa overlap (1-618:1-618) 10 20 30 40 50 60 pF1KE0 MASRGARQRLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 MASRGARQRLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 AFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 LLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 EPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 EPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFII 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFIQPHKEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 FFIQPHKEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 ALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 ALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 RFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 RFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 HYLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 HYLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVN 550 560 570 580 590 600 610 pF1KE0 YTILKPRKAKQIRKKSGG :::::::::::::::::: NP_079 YTILKPRKAKQIRKKSGG 610 >>XP_005277780 (OMIM: 263210,606941,608776) PREDICTED: a (629 aa) initn: 4233 init1: 4233 opt: 4233 Z-score: 4897.7 bits: 916.4 E(85289): 0 Smith-Waterman score: 4233; 100.0% identity (100.0% similar) in 617 aa overlap (1-617:1-617) 10 20 30 40 50 60 pF1KE0 MASRGARQRLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MASRGARQRLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 EPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFII 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFIQPHKEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FFIQPHKEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 ALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 RFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 HYLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HYLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVN 550 560 570 580 590 600 610 pF1KE0 YTILKPRKAKQIRKKSGG ::::::::::::::::: XP_005 YTILKPRKAKQIRKKSGDRRRAEPTYRKN 610 620 >>NP_001071158 (OMIM: 263210,606941,608776) alpha-1,2-ma (611 aa) initn: 2675 init1: 2675 opt: 4166 Z-score: 4820.3 bits: 902.0 E(85289): 0 Smith-Waterman score: 4166; 98.9% identity (98.9% similar) in 618 aa overlap (1-618:1-611) 10 20 30 40 50 60 pF1KE0 MASRGARQRLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASRGARQRLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 EPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFII 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFIQPHKEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWL ::::::::::::::::::::::::::::::: :::::::::::::::::::::: NP_001 FFIQPHKEERFLFPVYPLICLCGAVALSALQ-------KCYHFVFQRYRLEHYTVTSNWL 370 380 390 400 410 430 440 450 460 470 480 pF1KE0 ALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWY 420 430 440 450 460 470 490 500 510 520 530 540 pF1KE0 RFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKC 480 490 500 510 520 530 550 560 570 580 590 600 pF1KE0 HYLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HYLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVN 540 550 560 570 580 590 610 pF1KE0 YTILKPRKAKQIRKKSGG :::::::::::::::::: NP_001 YTILKPRKAKQIRKKSGG 600 610 >>XP_005277781 (OMIM: 263210,606941,608776) PREDICTED: a (622 aa) initn: 2675 init1: 2675 opt: 4158 Z-score: 4810.9 bits: 900.3 E(85289): 0 Smith-Waterman score: 4158; 98.9% identity (98.9% similar) in 617 aa overlap (1-617:1-610) 10 20 30 40 50 60 pF1KE0 MASRGARQRLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MASRGARQRLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 EPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFII 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFIQPHKEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWL ::::::::::::::::::::::::::::::: :::::::::::::::::::::: XP_005 FFIQPHKEERFLFPVYPLICLCGAVALSALQ-------KCYHFVFQRYRLEHYTVTSNWL 370 380 390 400 410 430 440 450 460 470 480 pF1KE0 ALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWY 420 430 440 450 460 470 490 500 510 520 530 540 pF1KE0 RFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKC 480 490 500 510 520 530 550 560 570 580 590 600 pF1KE0 HYLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HYLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVN 540 550 560 570 580 590 610 pF1KE0 YTILKPRKAKQIRKKSGG ::::::::::::::::: XP_005 YTILKPRKAKQIRKKSGDRRRAEPTYRKN 600 610 620 >>XP_011541294 (OMIM: 263210,606941,608776) PREDICTED: a (618 aa) initn: 3991 init1: 3991 opt: 3992 Z-score: 4618.9 bits: 864.8 E(85289): 0 Smith-Waterman score: 3992; 99.1% identity (99.7% similar) in 585 aa overlap (1-585:1-585) 10 20 30 40 50 60 pF1KE0 MASRGARQRLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MASRGARQRLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 EPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFII 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFIQPHKEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFIQPHKEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 ALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 RFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 HYLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVN :::::::::::::::::::::::::::::::::::::::. . .: XP_011 HYLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSQFVAQAGLKLLGSSNPPTSAS 550 560 570 580 590 600 610 pF1KE0 YTILKPRKAKQIRKKSGG XP_011 QNIGITGLSHRAWPLTSP 610 >>XP_006718976 (OMIM: 263210,606941,608776) PREDICTED: a (598 aa) initn: 3979 init1: 3979 opt: 3979 Z-score: 4604.1 bits: 862.0 E(85289): 0 Smith-Waterman score: 3979; 100.0% identity (100.0% similar) in 577 aa overlap (1-577:1-577) 10 20 30 40 50 60 pF1KE0 MASRGARQRLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MASRGARQRLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 EPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFII 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFIQPHKEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FFIQPHKEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 ALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 RFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 HYLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVN ::::::::::::::::::::::::::::::::::::: XP_006 HYLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASSFLSDAKNTEKQEEEIRVSIL 550 560 570 580 590 610 pF1KE0 YTILKPRKAKQIRKKSGG >>XP_016873802 (OMIM: 263210,606941,608776) PREDICTED: a (611 aa) initn: 2677 init1: 2677 opt: 3917 Z-score: 4532.2 bits: 848.7 E(85289): 0 Smith-Waterman score: 3917; 97.9% identity (98.5% similar) in 585 aa overlap (1-585:1-578) 10 20 30 40 50 60 pF1KE0 MASRGARQRLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MASRGARQRLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 EPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFII 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FFIQPHKEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWL ::::::::::::::::::::::::::::::: :::::::::::::::::::::: XP_016 FFIQPHKEERFLFPVYPLICLCGAVALSALQ-------KCYHFVFQRYRLEHYTVTSNWL 370 380 390 400 410 430 440 450 460 470 480 pF1KE0 ALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWY 420 430 440 450 460 470 490 500 510 520 530 540 pF1KE0 RFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKC 480 490 500 510 520 530 550 560 570 580 590 600 pF1KE0 HYLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVN :::::::::::::::::::::::::::::::::::::::. . .: XP_016 HYLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSQFVAQAGLKLLGSSNPPTSAS 540 550 560 570 580 590 610 pF1KE0 YTILKPRKAKQIRKKSGG XP_016 QNIGITGLSHRAWPLTSP 600 610 >>XP_016873808 (OMIM: 263210,606941,608776) PREDICTED: a (447 aa) initn: 3074 init1: 3074 opt: 3074 Z-score: 3558.6 bits: 668.1 E(85289): 1.8e-191 Smith-Waterman score: 3074; 100.0% identity (100.0% similar) in 447 aa overlap (172-618:1-447) 150 160 170 180 190 200 pF1KE0 LRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTGMFCSSSAFLPSSFCMYTTL :::::::::::::::::::::::::::::: XP_016 MMLAFLVLSTGMFCSSSAFLPSSFCMYTTL 10 20 30 210 220 230 240 250 260 pF1KE0 IAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFDLLVMKHRWKSFFHWSLMALIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFDLLVMKHRWKSFFHWSLMALIL 40 50 60 70 80 90 270 280 290 300 310 320 pF1KE0 FLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFYLINGFLNFNVAFALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFYLINGFLNFNVAFALA 100 110 120 130 140 150 330 340 350 360 370 380 pF1KE0 LLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICL 160 170 180 190 200 210 390 400 410 420 430 440 pF1KE0 CGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFR 220 230 240 250 260 270 450 460 470 480 490 500 pF1KE0 GYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWYRFPSSFLLPDNWQLQFIPSEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWYRFPSSFLLPDNWQLQFIPSEF 280 290 300 310 320 330 510 520 530 540 550 560 pF1KE0 RGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKCHYLVDLDTMRETPREPKYSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKCHYLVDLDTMRETPREPKYSSN 340 350 360 370 380 390 570 580 590 600 610 pF1KE0 KEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVNYTILKPRKAKQIRKKSGG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVNYTILKPRKAKQIRKKSGG 400 410 420 430 440 >>NP_001071159 (OMIM: 263210,606941,608776) alpha-1,2-ma (447 aa) initn: 3074 init1: 3074 opt: 3074 Z-score: 3558.6 bits: 668.1 E(85289): 1.8e-191 Smith-Waterman score: 3074; 100.0% identity (100.0% similar) in 447 aa overlap (172-618:1-447) 150 160 170 180 190 200 pF1KE0 LRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTGMFCSSSAFLPSSFCMYTTL :::::::::::::::::::::::::::::: NP_001 MMLAFLVLSTGMFCSSSAFLPSSFCMYTTL 10 20 30 210 220 230 240 250 260 pF1KE0 IAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFDLLVMKHRWKSFFHWSLMALIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFDLLVMKHRWKSFFHWSLMALIL 40 50 60 70 80 90 270 280 290 300 310 320 pF1KE0 FLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFYLINGFLNFNVAFALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFYLINGFLNFNVAFALA 100 110 120 130 140 150 330 340 350 360 370 380 pF1KE0 LLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICL 160 170 180 190 200 210 390 400 410 420 430 440 pF1KE0 CGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFR 220 230 240 250 260 270 450 460 470 480 490 500 pF1KE0 GYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWYRFPSSFLLPDNWQLQFIPSEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWYRFPSSFLLPDNWQLQFIPSEF 280 290 300 310 320 330 510 520 530 540 550 560 pF1KE0 RGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKCHYLVDLDTMRETPREPKYSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKCHYLVDLDTMRETPREPKYSSN 340 350 360 370 380 390 570 580 590 600 610 pF1KE0 KEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVNYTILKPRKAKQIRKKSGG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVNYTILKPRKAKQIRKKSGG 400 410 420 430 440 >>XP_016873809 (OMIM: 263210,606941,608776) PREDICTED: a (447 aa) initn: 3074 init1: 3074 opt: 3074 Z-score: 3558.6 bits: 668.1 E(85289): 1.8e-191 Smith-Waterman score: 3074; 100.0% identity (100.0% similar) in 447 aa overlap (172-618:1-447) 150 160 170 180 190 200 pF1KE0 LRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTGMFCSSSAFLPSSFCMYTTL :::::::::::::::::::::::::::::: XP_016 MMLAFLVLSTGMFCSSSAFLPSSFCMYTTL 10 20 30 210 220 230 240 250 260 pF1KE0 IAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFDLLVMKHRWKSFFHWSLMALIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAFDLLVMKHRWKSFFHWSLMALIL 40 50 60 70 80 90 270 280 290 300 310 320 pF1KE0 FLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFYLINGFLNFNVAFALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFYLINGFLNFNVAFALA 100 110 120 130 140 150 330 340 350 360 370 380 pF1KE0 LLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICL 160 170 180 190 200 210 390 400 410 420 430 440 pF1KE0 CGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFR 220 230 240 250 260 270 450 460 470 480 490 500 pF1KE0 GYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWYRFPSSFLLPDNWQLQFIPSEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWYRFPSSFLLPDNWQLQFIPSEF 280 290 300 310 320 330 510 520 530 540 550 560 pF1KE0 RGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKCHYLVDLDTMRETPREPKYSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGQLPKPFAEGPLATRIVPTDMNDQNLEEPSRYIDISKCHYLVDLDTMRETPREPKYSSN 340 350 360 370 380 390 570 580 590 600 610 pF1KE0 KEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVNYTILKPRKAKQIRKKSGG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVNYTILKPRKAKQIRKKSGG 400 410 420 430 440 618 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:48:46 2016 done: Thu Nov 3 15:48:47 2016 Total Scan time: 10.560 Total Display time: 0.150 Function used was FASTA [36.3.4 Apr, 2011]