FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0331, 654 aa 1>>>pF1KE0331 654 - 654 aa - 654 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6125+/-0.00104; mu= 13.5198+/- 0.063 mean_var=98.4687+/-19.428, 0's: 0 Z-trim(105.5): 18 B-trim: 85 in 1/50 Lambda= 0.129248 statistics sampled from 8433 (8439) to 8433 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.259), width: 16 Scan time: 3.520 The best scores are: opt bits E(32554) CCDS9672.1 MIA2 gene_id:4253|Hs108|chr14 ( 654) 4270 807.2 0 CCDS41470.1 MIA3 gene_id:375056|Hs108|chr1 (1907) 381 82.2 7.1e-15 >>CCDS9672.1 MIA2 gene_id:4253|Hs108|chr14 (654 aa) initn: 4270 init1: 4270 opt: 4270 Z-score: 4306.8 bits: 807.2 E(32554): 0 Smith-Waterman score: 4270; 99.5% identity (99.8% similar) in 654 aa overlap (1-654:1-654) 10 20 30 40 50 60 pF1KE0 MAKFGVHRILLLAISLTKCLESTKLLADLKKCGDLECEALINRVSAMRDYRGPDCRYLNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 MAKFGVHRILLLAISLTKCLESTKLLADLKKCGDLECEALINRVSAMRDYRGPDCRYLNF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TKGEEISVYVKLAGEREDLWAGSKGKEFGYFPRDAVQIEEVFISEEIQMSTKESDFLCLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 TKGEEISVYVKLAGEREDLWAGSKGKEFGYFPRDAVQIEEVFISEEIQMSTKESDFLCLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GVSYTFDNEDSELNGDYGENIYPYEEDKDEKSSIYESDFQIEPGFYATYESTLFEDQVPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 GVSYTFDNEDSELNGDYGENIYPYEEDKDEKSSIYESDFQIEPGFYATYESTLFEDQVPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LEAPEDIGSTSESKDWEEVVVESMEQDRIPEVHVPPSSAVSGVKEWFGLGGEQAEEKAFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 LEAPEDIGSTSESKDWEEVVVESMEQDRIPEVHVPPSSAVSGVKEWFGLGGEQAEEKAFE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 SVIEPVQESSFRSRKIAVEDENDLEELNNGEPQTEHQQESESEIDSVPRTQSELASESEH ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: CCDS96 SVIEPVQESSFRSRKIAVEDENDLEELNNGEPQTEHQQESESEIDSVPKTQSELASESEH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 IPKPQSTGWFGGGFTSYSGFGDEDTGLELIAEESNPPLQDFPNSISSDKEATVPCTEILT ::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::: CCDS96 IPKPQSTGWFGGGFTSYLGFGDEDTGLELIAEESNPPLQDFPNSISSDKEATVPCTEILT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 EKKDTITNDSLSLKPSWFDFGFAILGFAYAKEDKIMLDDRKNEEDGGADEHEHPLTSELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 EKKDTITNDSLSLKPSWFDFGFAILGFAYAKEDKIMLDDRKNEEDGGADEHEHPLTSELD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 PEKEQEIETIKIIETEDQIDKKPVSEKTDESDTIPYLKKFLYNFDNPWNFQNIPKETELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 PEKEQEIETIKIIETEDQIDKKPVSEKTDESDTIPYLKKFLYNFDNPWNFQNIPKETELP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 FPKQILDQNNVIENEETGEFSIDNYPTDNTKVMIFKSSYSLSDMVSNIELPTRIHEEVYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 FPKQILDQNNVIENEETGEFSIDNYPTDNTKVMIFKSSYSLSDMVSNIELPTRIHEEVYF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 EPSSSKDSDENSKPSVDTEGPALVEIDRSVENTLLNSQMVSTDNSLSSQNYISQKEDASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 EPSSSKDSDENSKPSVDTEGPALVEIDRSVENTLLNSQMVSTDNSLSSQNYISQKEDASE 550 560 570 580 590 600 610 620 630 640 650 pF1KE0 FQILKYLFQIDVYDFMNSAFSPIVILTERVSLPFKPFAIILPILLNIRVAAKYV ::::::::::::::::::::::::::::::::::::::::::::::::::.::: CCDS96 FQILKYLFQIDVYDFMNSAFSPIVILTERVSLPFKPFAIILPILLNIRVATKYV 610 620 630 640 650 >>CCDS41470.1 MIA3 gene_id:375056|Hs108|chr1 (1907 aa) initn: 378 init1: 347 opt: 381 Z-score: 380.5 bits: 82.2 E(32554): 7.1e-15 Smith-Waterman score: 407; 25.8% identity (52.9% similar) in 403 aa overlap (26-410:32-416) 10 20 30 40 50 pF1KE0 MAKFGVHRILLLAISLTKCLESTKLLADLKKCGDLECEALINRVSAMRDYRGPDC ... : :.: :: :. : :..:. :::: CCDS41 AAAPGLLVWLLVLRLPWRVPGQLDPSTGRRFSEHKLCADDECSMLMYRGEALEDFTGPDC 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 RYLNFTKGEEISVYVKLAGEREDLWAGSKGKEFGYFPRDAVQIEEVFISEEIQMSTKESD :..:: ::. . :: ::: ..:::: :. :::::.: .:. . . .::.:. : :.: CCDS41 RFVNFKKGDPVYVYYKLARGWPEVWAGSVGRTFGYFPKDLIQVVHEYTKEELQVPTDETD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 FLCLLGVSYTFDNEDSELNGDYGENIYPYEEDKDEKSSIYESDFQIEPGFYATYESTLFE :.:. : : : . : . : :... .:.. .: : . CCDS41 FVCFDGGRDDFHNYNVEELLGFLELYNSAATDSEKAVEKTLQDMEKNP--------ELSK 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 DQVPALEAPEDIGSTSESKD--WEEVVVESMEQDRIPEVHVPPSSAVSGVKEWFGLGGEQ .. : :: . ..:: .: . : . . .:: . : .: .. .. ::: CCDS41 EREPE---PEPVEANSEESDSVFSENTEDLQEQFTTQKHHSHANSQANHAQ------GEQ 180 190 200 210 220 240 250 260 270 280 pF1KE0 AEEKAFESVIE-----PVQESSFRSRKIAV---EDENDLEELNNGEPQTEHQQESESEID : ..:: ... : .:.. : . : .:. : .: . : . . . : : CCDS41 ASFESFEEMLQDKLKVPESENNKTSNSSQVSNEQDKIDAYKLLKKEMTLDLKTKFGSTAD 230 240 250 260 270 280 290 300 310 320 330 pF1KE0 SV---PRTQSELASESEHIPKPQSTGWFGGGFTSYSGFGDEDTGLELIA----EESNPPL .. .: ..: . . . .: ... : . . : : : :.. :. . : CCDS41 ALVSDDETTRLVTSLEDDFDEELDTEYYAVGKEDEENQEDFDE-LPLLTFTDGEDMKTPA 290 300 310 320 330 340 340 350 360 370 380 390 pF1KE0 QDFPNSISSDKEA-TVPCTEILTEKKDTITNDSLSLKPSWFDFGFAILGFAYAKEDKIML .. .. .::: . .. : ::. .. .: : :.:. . .: . : CCDS41 KSGVEKYPTDKEQNSNEEDKVQLTVPPGIKNDDKNILTTWGDTIFSIVTGGEETRDTMDL 350 360 370 380 390 400 400 410 420 430 440 450 pF1KE0 DDRKNEEDGGADEHEHPLTSELDPEKEQEIETIKIIETEDQIDKKPVSEKTDESDTIPYL .. ..::. :. CCDS41 ESSSSEEEKEDDDDALVPDSKQGKPQSATDYSDPDNVDDGLFIVDIPKTNNDKEVNAEHH 410 420 430 440 450 460 654 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:38:02 2016 done: Thu Nov 3 15:38:03 2016 Total Scan time: 3.520 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]