FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0341, 684 aa 1>>>pF1KE0341 684 - 684 aa - 684 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5430+/-0.000367; mu= 18.3180+/- 0.023 mean_var=71.4218+/-14.467, 0's: 0 Z-trim(112.7): 41 B-trim: 0 in 0/50 Lambda= 0.151760 statistics sampled from 21758 (21790) to 21758 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.255), width: 16 Scan time: 11.690 The best scores are: opt bits E(85289) NP_001095841 (OMIM: 613777) FAD-dependent oxidored ( 684) 4629 1023.2 0 NP_079231 (OMIM: 613777) FAD-dependent oxidoreduct ( 684) 4629 1023.2 0 XP_016884430 (OMIM: 613777) PREDICTED: FAD-depende ( 594) 2279 508.6 2.6e-143 XP_016884431 (OMIM: 613777) PREDICTED: FAD-depende ( 594) 2279 508.6 2.6e-143 NP_001138302 (OMIM: 603957) dimethylaniline monoox ( 285) 178 48.5 4.2e-05 XP_006711308 (OMIM: 603957) PREDICTED: dimethylani ( 285) 178 48.5 4.2e-05 XP_006711307 (OMIM: 603957) PREDICTED: dimethylani ( 332) 178 48.5 4.8e-05 NP_001138301 (OMIM: 603957) dimethylaniline monoox ( 464) 178 48.6 6.4e-05 XP_011507652 (OMIM: 603957) PREDICTED: dimethylani ( 533) 178 48.6 7.2e-05 XP_005273005 (OMIM: 603957) PREDICTED: dimethylani ( 533) 178 48.6 7.2e-05 XP_005273003 (OMIM: 603957) PREDICTED: dimethylani ( 533) 178 48.6 7.2e-05 NP_001452 (OMIM: 603957) dimethylaniline monooxyge ( 533) 178 48.6 7.2e-05 XP_005273004 (OMIM: 603957) PREDICTED: dimethylani ( 533) 178 48.6 7.2e-05 NP_008825 (OMIM: 136132,602079) dimethylaniline mo ( 532) 154 43.4 0.0027 NP_001002294 (OMIM: 136132,602079) dimethylaniline ( 532) 154 43.4 0.0027 XP_011507653 (OMIM: 603957) PREDICTED: dimethylani ( 470) 146 41.6 0.0083 XP_016856290 (OMIM: 603957) PREDICTED: dimethylani ( 470) 146 41.6 0.0083 XP_016856291 (OMIM: 603957) PREDICTED: dimethylani ( 470) 146 41.6 0.0083 >>NP_001095841 (OMIM: 613777) FAD-dependent oxidoreducta (684 aa) initn: 4629 init1: 4629 opt: 4629 Z-score: 5473.5 bits: 1023.2 E(85289): 0 Smith-Waterman score: 4629; 99.7% identity (100.0% similar) in 684 aa overlap (1-684:1-684) 10 20 30 40 50 60 pF1KE0 MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYFP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQVHQCSVLLV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.: NP_001 DARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQVHQCSVLFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 MLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILKDSKGKFHVTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILKDSKGKFHVTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 KFFLEEASTNQSADSITLPQDDNDNFAMRVPYDRVIRCLGWNFDFSIFNKSLRLNSGNAF :::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFFLEEANTNQSADSITLPQDDNDNFAMRVPYDRVIRCLGWNFDFSIFNKSLRLNSGNAF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 GKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHSV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 TWPATELPITQLTSSIVRRVNEASGLYQMFGVLADVILLKENSTAFEYLEEFPIQMLAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TWPATELPITQLTSSIVRRVNEASGLYQMFGVLADVILLKENSTAFEYLEEFPIQMLAQL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 ETLTGRKAKHGLFVINMEYGRNFSGPDKDVFFDDRSVGHTEDAWQSNFLHPVIYYYRYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETLTGRKAKHGLFVINMEYGRNFSGPDKDVFFDDRSVGHTEDAWQSNFLHPVIYYYRYLP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 TEQEVRFRPAHWPLPRPTAIHHIVEDFLTDWTAPIGHILPLRRFLENCLDTDLRSFYAES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEQEVRFRPAHWPLPRPTAIHHIVEDFLTDWTAPIGHILPLRRFLENCLDTDLRSFYAES 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 CFLFALTRQKLPPFCQQGYLRMQGLVSTESLWQHRVESRLLRDYAPTGRRLEDSSQQLGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFLFALTRQKLPPFCQQGYLRMQGLVSTESLWQHRVESRLLRDYAPTGRRLEDSSQQLGD 610 620 630 640 650 660 670 680 pF1KE0 QEPLGSPLAPGPLAQSVDSNKEEL :::::::::::::::::::::::: NP_001 QEPLGSPLAPGPLAQSVDSNKEEL 670 680 >>NP_079231 (OMIM: 613777) FAD-dependent oxidoreductase (684 aa) initn: 4629 init1: 4629 opt: 4629 Z-score: 5473.5 bits: 1023.2 E(85289): 0 Smith-Waterman score: 4629; 99.7% identity (100.0% similar) in 684 aa overlap (1-684:1-684) 10 20 30 40 50 60 pF1KE0 MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 RAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYFP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQVHQCSVLLV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.: NP_079 DARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQVHQCSVLFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 ATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 MLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILKDSKGKFHVTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 MLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILKDSKGKFHVTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 KFFLEEASTNQSADSITLPQDDNDNFAMRVPYDRVIRCLGWNFDFSIFNKSLRLNSGNAF :::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 KFFLEEANTNQSADSITLPQDDNDNFAMRVPYDRVIRCLGWNFDFSIFNKSLRLNSGNAF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 GKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 GKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHSV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 TWPATELPITQLTSSIVRRVNEASGLYQMFGVLADVILLKENSTAFEYLEEFPIQMLAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 TWPATELPITQLTSSIVRRVNEASGLYQMFGVLADVILLKENSTAFEYLEEFPIQMLAQL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 ETLTGRKAKHGLFVINMEYGRNFSGPDKDVFFDDRSVGHTEDAWQSNFLHPVIYYYRYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 ETLTGRKAKHGLFVINMEYGRNFSGPDKDVFFDDRSVGHTEDAWQSNFLHPVIYYYRYLP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 TEQEVRFRPAHWPLPRPTAIHHIVEDFLTDWTAPIGHILPLRRFLENCLDTDLRSFYAES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 TEQEVRFRPAHWPLPRPTAIHHIVEDFLTDWTAPIGHILPLRRFLENCLDTDLRSFYAES 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 CFLFALTRQKLPPFCQQGYLRMQGLVSTESLWQHRVESRLLRDYAPTGRRLEDSSQQLGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 CFLFALTRQKLPPFCQQGYLRMQGLVSTESLWQHRVESRLLRDYAPTGRRLEDSSQQLGD 610 620 630 640 650 660 670 680 pF1KE0 QEPLGSPLAPGPLAQSVDSNKEEL :::::::::::::::::::::::: NP_079 QEPLGSPLAPGPLAQSVDSNKEEL 670 680 >>XP_016884430 (OMIM: 613777) PREDICTED: FAD-dependent o (594 aa) initn: 2269 init1: 2269 opt: 2279 Z-score: 2693.8 bits: 508.6 E(85289): 2.6e-143 Smith-Waterman score: 3846; 86.7% identity (86.8% similar) in 684 aa overlap (1-684:1-594) 10 20 30 40 50 60 pF1KE0 MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYFP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQVHQCSVLLV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.: XP_016 DARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQVHQCSVLFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 MLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILKDSKGKFHVTP :::::::::::::::::::: XP_016 MLSRSRVRLSWATHYVGDLR---------------------------------------- 250 260 310 320 330 340 350 360 pF1KE0 KFFLEEASTNQSADSITLPQDDNDNFAMRVPYDRVIRCLGWNFDFSIFNKSLRLNSGNAF :::::::::: XP_016 --------------------------------------------------SLRLNSGNAF 270 370 380 390 400 410 420 pF1KE0 GKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHSV 280 290 300 310 320 330 430 440 450 460 470 480 pF1KE0 TWPATELPITQLTSSIVRRVNEASGLYQMFGVLADVILLKENSTAFEYLEEFPIQMLAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWPATELPITQLTSSIVRRVNEASGLYQMFGVLADVILLKENSTAFEYLEEFPIQMLAQL 340 350 360 370 380 390 490 500 510 520 530 540 pF1KE0 ETLTGRKAKHGLFVINMEYGRNFSGPDKDVFFDDRSVGHTEDAWQSNFLHPVIYYYRYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETLTGRKAKHGLFVINMEYGRNFSGPDKDVFFDDRSVGHTEDAWQSNFLHPVIYYYRYLP 400 410 420 430 440 450 550 560 570 580 590 600 pF1KE0 TEQEVRFRPAHWPLPRPTAIHHIVEDFLTDWTAPIGHILPLRRFLENCLDTDLRSFYAES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEQEVRFRPAHWPLPRPTAIHHIVEDFLTDWTAPIGHILPLRRFLENCLDTDLRSFYAES 460 470 480 490 500 510 610 620 630 640 650 660 pF1KE0 CFLFALTRQKLPPFCQQGYLRMQGLVSTESLWQHRVESRLLRDYAPTGRRLEDSSQQLGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CFLFALTRQKLPPFCQQGYLRMQGLVSTESLWQHRVESRLLRDYAPTGRRLEDSSQQLGD 520 530 540 550 560 570 670 680 pF1KE0 QEPLGSPLAPGPLAQSVDSNKEEL :::::::::::::::::::::::: XP_016 QEPLGSPLAPGPLAQSVDSNKEEL 580 590 >>XP_016884431 (OMIM: 613777) PREDICTED: FAD-dependent o (594 aa) initn: 2269 init1: 2269 opt: 2279 Z-score: 2693.8 bits: 508.6 E(85289): 2.6e-143 Smith-Waterman score: 3846; 86.7% identity (86.8% similar) in 684 aa overlap (1-684:1-594) 10 20 30 40 50 60 pF1KE0 MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYFP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQVHQCSVLLV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.: XP_016 DARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQVHQCSVLFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 MLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILKDSKGKFHVTP :::::::::::::::::::: XP_016 MLSRSRVRLSWATHYVGDLR---------------------------------------- 250 260 310 320 330 340 350 360 pF1KE0 KFFLEEASTNQSADSITLPQDDNDNFAMRVPYDRVIRCLGWNFDFSIFNKSLRLNSGNAF :::::::::: XP_016 --------------------------------------------------SLRLNSGNAF 270 370 380 390 400 410 420 pF1KE0 GKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHSV 280 290 300 310 320 330 430 440 450 460 470 480 pF1KE0 TWPATELPITQLTSSIVRRVNEASGLYQMFGVLADVILLKENSTAFEYLEEFPIQMLAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWPATELPITQLTSSIVRRVNEASGLYQMFGVLADVILLKENSTAFEYLEEFPIQMLAQL 340 350 360 370 380 390 490 500 510 520 530 540 pF1KE0 ETLTGRKAKHGLFVINMEYGRNFSGPDKDVFFDDRSVGHTEDAWQSNFLHPVIYYYRYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETLTGRKAKHGLFVINMEYGRNFSGPDKDVFFDDRSVGHTEDAWQSNFLHPVIYYYRYLP 400 410 420 430 440 450 550 560 570 580 590 600 pF1KE0 TEQEVRFRPAHWPLPRPTAIHHIVEDFLTDWTAPIGHILPLRRFLENCLDTDLRSFYAES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEQEVRFRPAHWPLPRPTAIHHIVEDFLTDWTAPIGHILPLRRFLENCLDTDLRSFYAES 460 470 480 490 500 510 610 620 630 640 650 660 pF1KE0 CFLFALTRQKLPPFCQQGYLRMQGLVSTESLWQHRVESRLLRDYAPTGRRLEDSSQQLGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CFLFALTRQKLPPFCQQGYLRMQGLVSTESLWQHRVESRLLRDYAPTGRRLEDSSQQLGD 520 530 540 550 560 570 670 680 pF1KE0 QEPLGSPLAPGPLAQSVDSNKEEL :::::::::::::::::::::::: XP_016 QEPLGSPLAPGPLAQSVDSNKEEL 580 590 >>NP_001138302 (OMIM: 603957) dimethylaniline monooxygen (285 aa) initn: 107 init1: 74 opt: 178 Z-score: 212.5 bits: 48.5 E(85289): 4.2e-05 Smith-Waterman score: 178; 25.1% identity (53.1% similar) in 239 aa overlap (30-258:3-227) 10 20 30 40 50 60 pF1KE0 MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFE .. :.:.: .::. . : . . :: NP_001 MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFE 10 20 30 70 80 90 100 110 pF1KE0 RAPRPGSF--FTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAY :. :.. : . :.. . :: : ... :. :. . .: : .. : NP_001 RTDDIGGLWRFQENPEEGR-ASIYKSVIINTSKEMMCFSDY-PIPDHYPNFMHNAQVLEY 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 FPDARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQ--VHQCS : :. . : : ....::. : . : : .:.. ..:...:. .. . NP_001 F-------RMYAKEFDLLKY-IRFKTTVCSVKKQPDF-ATSGQWEVVTESEGKKEMNVFD 100 110 120 130 140 180 190 200 210 220 230 pF1KE0 VLLVATGLSVPNQV---DFPGSEYAEGYESVSVD---PEDFVGQNVLILGRGNSAFETAE ..: :: . .. .::: : .: : : :: :.:. :.:.: :::. . : NP_001 GVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAV 150 160 170 180 190 200 240 250 260 270 280 290 pF1KE0 NILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILK .: ... . . .: : .: . ::: NP_001 EISQTAKQVFLSTR---RGAWILNRVGDYGYPADVLFSSRLTHFIWKICGQSLANKYLEK 210 220 230 240 250 >>XP_006711308 (OMIM: 603957) PREDICTED: dimethylaniline (285 aa) initn: 107 init1: 74 opt: 178 Z-score: 212.5 bits: 48.5 E(85289): 4.2e-05 Smith-Waterman score: 178; 25.1% identity (53.1% similar) in 239 aa overlap (30-258:3-227) 10 20 30 40 50 60 pF1KE0 MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFE .. :.:.: .::. . : . . :: XP_006 MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFE 10 20 30 70 80 90 100 110 pF1KE0 RAPRPGSF--FTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAY :. :.. : . :.. . :: : ... :. :. . .: : .. : XP_006 RTDDIGGLWRFQENPEEGR-ASIYKSVIINTSKEMMCFSDY-PIPDHYPNFMHNAQVLEY 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 FPDARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQ--VHQCS : :. . : : ....::. : . : : .:.. ..:...:. .. . XP_006 F-------RMYAKEFDLLKY-IRFKTTVCSVKKQPDF-ATSGQWEVVTESEGKKEMNVFD 100 110 120 130 140 180 190 200 210 220 230 pF1KE0 VLLVATGLSVPNQV---DFPGSEYAEGYESVSVD---PEDFVGQNVLILGRGNSAFETAE ..: :: . .. .::: : .: : : :: :.:. :.:.: :::. . : XP_006 GVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAV 150 160 170 180 190 200 240 250 260 270 280 290 pF1KE0 NILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILK .: ... . . .: : .: . ::: XP_006 EISQTAKQVFLSTR---RGAWILNRVGDYGYPADVLFSSRLTHFIWKICGQSLANKYLEK 210 220 230 240 250 >>XP_006711307 (OMIM: 603957) PREDICTED: dimethylaniline (332 aa) initn: 74 init1: 74 opt: 178 Z-score: 211.5 bits: 48.5 E(85289): 4.8e-05 Smith-Waterman score: 178; 25.1% identity (53.1% similar) in 239 aa overlap (30-258:3-227) 10 20 30 40 50 60 pF1KE0 MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFE .. :.:.: .::. . : . . :: XP_006 MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFE 10 20 30 70 80 90 100 110 pF1KE0 RAPRPGSF--FTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAY :. :.. : . :.. . :: : ... :. :. . .: : .. : XP_006 RTDDIGGLWRFQENPEEGR-ASIYKSVIINTSKEMMCFSDY-PIPDHYPNFMHNAQVLEY 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 FPDARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQ--VHQCS : :. . : : ....::. : . : : .:.. ..:...:. .. . XP_006 F-------RMYAKEFDLLKY-IRFKTTVCSVKKQPDF-ATSGQWEVVTESEGKKEMNVFD 100 110 120 130 140 180 190 200 210 220 230 pF1KE0 VLLVATGLSVPNQV---DFPGSEYAEGYESVSVD---PEDFVGQNVLILGRGNSAFETAE ..: :: . .. .::: : .: : : :: :.:. :.:.: :::. . : XP_006 GVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAV 150 160 170 180 190 200 240 250 260 270 280 290 pF1KE0 NILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILK .: ... . . .: : .: . ::: XP_006 EISQTAKQVFLSTR---RGAWILNRVGDYGYPADVLFSSRLTHFIWKICGQSLANKYLEK 210 220 230 240 250 >>NP_001138301 (OMIM: 603957) dimethylaniline monooxygen (464 aa) initn: 109 init1: 74 opt: 178 Z-score: 209.3 bits: 48.6 E(85289): 6.4e-05 Smith-Waterman score: 178; 25.1% identity (53.1% similar) in 239 aa overlap (30-258:3-227) 10 20 30 40 50 60 pF1KE0 MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFE .. :.:.: .::. . : . . :: NP_001 MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFE 10 20 30 70 80 90 100 110 pF1KE0 RAPRPGSF--FTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAY :. :.. : . :.. . :: : ... :. :. . .: : .. : NP_001 RTDDIGGLWRFQENPEEGR-ASIYKSVIINTSKEMMCFSDY-PIPDHYPNFMHNAQVLEY 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 FPDARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQ--VHQCS : :. . : : ....::. : . : : .:.. ..:...:. .. . NP_001 F-------RMYAKEFDLLKY-IRFKTTVCSVKKQPDF-ATSGQWEVVTESEGKKEMNVFD 100 110 120 130 140 180 190 200 210 220 230 pF1KE0 VLLVATGLSVPNQV---DFPGSEYAEGYESVSVD---PEDFVGQNVLILGRGNSAFETAE ..: :: . .. .::: : .: : : :: :.:. :.:.: :::. . : NP_001 GVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAV 150 160 170 180 190 200 240 250 260 270 280 290 pF1KE0 NILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILK .: ... . . .: : .: . ::: NP_001 EISQTAKQVFLSTR---RGAWILNRVGDYGYPADVLFSSRLTHFIWKICGQSLANKYLEK 210 220 230 240 250 >>XP_011507652 (OMIM: 603957) PREDICTED: dimethylaniline (533 aa) initn: 109 init1: 74 opt: 178 Z-score: 208.4 bits: 48.6 E(85289): 7.2e-05 Smith-Waterman score: 178; 25.1% identity (53.1% similar) in 239 aa overlap (30-258:3-227) 10 20 30 40 50 60 pF1KE0 MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFE .. :.:.: .::. . : . . :: XP_011 MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFE 10 20 30 70 80 90 100 110 pF1KE0 RAPRPGSF--FTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAY :. :.. : . :.. . :: : ... :. :. . .: : .. : XP_011 RTDDIGGLWRFQENPEEGR-ASIYKSVIINTSKEMMCFSDY-PIPDHYPNFMHNAQVLEY 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 FPDARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQ--VHQCS : :. . : : ....::. : . : : .:.. ..:...:. .. . XP_011 F-------RMYAKEFDLLKY-IRFKTTVCSVKKQPDF-ATSGQWEVVTESEGKKEMNVFD 100 110 120 130 140 180 190 200 210 220 230 pF1KE0 VLLVATGLSVPNQV---DFPGSEYAEGYESVSVD---PEDFVGQNVLILGRGNSAFETAE ..: :: . .. .::: : .: : : :: :.:. :.:.: :::. . : XP_011 GVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAV 150 160 170 180 190 200 240 250 260 270 280 290 pF1KE0 NILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILK .: ... . . .: : .: . ::: XP_011 EISQTAKQVFLSTR---RGAWILNRVGDYGYPADVLFSSRLTHFIWKICGQSLANKYLEK 210 220 230 240 250 >>XP_005273005 (OMIM: 603957) PREDICTED: dimethylaniline (533 aa) initn: 109 init1: 74 opt: 178 Z-score: 208.4 bits: 48.6 E(85289): 7.2e-05 Smith-Waterman score: 178; 25.1% identity (53.1% similar) in 239 aa overlap (30-258:3-227) 10 20 30 40 50 60 pF1KE0 MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFE .. :.:.: .::. . : . . :: XP_005 MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFE 10 20 30 70 80 90 100 110 pF1KE0 RAPRPGSF--FTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAY :. :.. : . :.. . :: : ... :. :. . .: : .. : XP_005 RTDDIGGLWRFQENPEEGR-ASIYKSVIINTSKEMMCFSDY-PIPDHYPNFMHNAQVLEY 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 FPDARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQ--VHQCS : :. . : : ....::. : . : : .:.. ..:...:. .. . XP_005 F-------RMYAKEFDLLKY-IRFKTTVCSVKKQPDF-ATSGQWEVVTESEGKKEMNVFD 100 110 120 130 140 180 190 200 210 220 230 pF1KE0 VLLVATGLSVPNQV---DFPGSEYAEGYESVSVD---PEDFVGQNVLILGRGNSAFETAE ..: :: . .. .::: : .: : : :: :.:. :.:.: :::. . : XP_005 GVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAV 150 160 170 180 190 200 240 250 260 270 280 290 pF1KE0 NILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILK .: ... . . .: : .: . ::: XP_005 EISQTAKQVFLSTR---RGAWILNRVGDYGYPADVLFSSRLTHFIWKICGQSLANKYLEK 210 220 230 240 250 684 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:09:04 2016 done: Thu Nov 3 15:09:05 2016 Total Scan time: 11.690 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]