FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0344, 707 aa 1>>>pF1KE0344 707 - 707 aa - 707 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1932+/-0.000783; mu= 21.2242+/- 0.047 mean_var=75.7541+/-15.202, 0's: 0 Z-trim(108.9): 10 B-trim: 0 in 0/49 Lambda= 0.147357 statistics sampled from 10534 (10539) to 10534 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.324), width: 16 Scan time: 3.990 The best scores are: opt bits E(32554) CCDS14093.2 LMF2 gene_id:91289|Hs108|chr22 ( 707) 4832 1036.9 0 CCDS45373.1 LMF1 gene_id:64788|Hs108|chr16 ( 567) 407 96.1 1.6e-19 >>CCDS14093.2 LMF2 gene_id:91289|Hs108|chr22 (707 aa) initn: 4832 init1: 4832 opt: 4832 Z-score: 5546.9 bits: 1036.9 E(32554): 0 Smith-Waterman score: 4832; 100.0% identity (100.0% similar) in 707 aa overlap (1-707:1-707) 10 20 30 40 50 60 pF1KE0 MAGSRLPRQLFLQGVAAVFMFAFASLYTQIPGLYGPEGILPARRTLRPQGKGRWQQLWET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MAGSRLPRQLFLQGVAAVFMFAFASLYTQIPGLYGPEGILPARRTLRPQGKGRWQQLWET 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PTLLWEAPRLGLDTAQGLELLSLLGALVALGALLLSPLRHPVIYLLLWAAYLSACQVGQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PTLLWEAPRLGLDTAQGLELLSLLGALVALGALLLSPLRHPVIYLLLWAAYLSACQVGQV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FLYFQWDSLLLETGFLAVLVAPLRPASHRKEAPQGRQAGALPHEDLPFWLVRWLLFRLMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 FLYFQWDSLLLETGFLAVLVAPLRPASHRKEAPQGRQAGALPHEDLPFWLVRWLLFRLMF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ASGVVKLTSRCPAWWGLTALTYHYETQCLPTPAAWFAHHLPVWLHKLSVVATFLIEIAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 ASGVVKLTSRCPAWWGLTALTYHYETQCLPTPAAWFAHHLPVWLHKLSVVATFLIEIAVP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 PLFFAPIRRLRLAAFYSQVLLQVLIIITGNYNFFNLMTLVLTTALLDDQHLAAEPGHGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PLFFAPIRRLRLAAFYSQVLLQVLIIITGNYNFFNLMTLVLTTALLDDQHLAAEPGHGSR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 KKTATSWPKALLATLSLLLELAVYGLLAYGTVHYFGLEVDWQQRTIHSRTTFTFHQFSQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 KKTATSWPKALLATLSLLLELAVYGLLAYGTVHYFGLEVDWQQRTIHSRTTFTFHQFSQW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 LKTLTLPTVWLGVASLVWELLSALWRWTQVRGWLRKLSAVVQLSLVGTATVALFLISLVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LKTLTLPTVWLGVASLVWELLSALWRWTQVRGWLRKLSAVVQLSLVGTATVALFLISLVP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 YSYVEPGTHGRLWTGAHRLFGAVEHLQLANSYGLFRRMTGLGGRPEVVLEGSYDGHHWTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 YSYVEPGTHGRLWTGAHRLFGAVEHLQLANSYGLFRRMTGLGGRPEVVLEGSYDGHHWTE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 IEFMYKPGNLSRPPPVVVPHQPRLDWQMWFAALGPHTHSPWFTSLVLRLLQGKEPVIRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 IEFMYKPGNLSRPPPVVVPHQPRLDWQMWFAALGPHTHSPWFTSLVLRLLQGKEPVIRLV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 QSQVARYPFHKQPPTYVRAQRYKYWFSQPGEQGQWWRRQWVEEFFPSVSLGDPTLETLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 QSQVARYPFHKQPPTYVRAQRYKYWFSQPGEQGQWWRRQWVEEFFPSVSLGDPTLETLLR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 QFGLQEKSPPRTRSANSTLAQALHWTRSQLSPLEAPALLWGLLMAVGAVRFVQALLAPCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 QFGLQEKSPPRTRSANSTLAQALHWTRSQLSPLEAPALLWGLLMAVGAVRFVQALLAPCS 610 620 630 640 650 660 670 680 690 700 pF1KE0 LRSSPLAPVSGEKRRPASQKDSGAASEQATAAPNPCSSSSRTTRRKK ::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LRSSPLAPVSGEKRRPASQKDSGAASEQATAAPNPCSSSSRTTRRKK 670 680 690 700 >>CCDS45373.1 LMF1 gene_id:64788|Hs108|chr16 (567 aa) initn: 596 init1: 177 opt: 407 Z-score: 464.2 bits: 96.1 E(32554): 1.6e-19 Smith-Waterman score: 792; 30.0% identity (54.9% similar) in 621 aa overlap (6-609:51-566) 10 20 30 pF1KE0 MAGSRLPRQLFLQGVAAVFMFAFASLYTQIPGLYG : : ..:...: :.. :: . : : : CCDS45 GYSDPEPESPPAPGRGPAGSPAHLHTGTFWLTRIVLLKALAFVYFVAFLVAFHQNKQLIG 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE0 PEGILPARRTLRP-----QGKGRWQQLWETPTLLWEAPRLGLDTAQGLELLSLLGALVAL .:.:: : :. : . :. . ::.:: : ..:.::.::: .. CCDS45 DRGLLPCRVFLKNFQQYFQDRTSWEVFSYMPTILWLMDWS--DMNSNLDLLALLGLGIS- 90 100 110 120 130 100 110 120 130 140 150 pF1KE0 GALLLSPLRHPVIYLLLWAAYLSACQVGQVFLYFQWDSLLLETGFLAVLVAPLRPASHRK . .:.. . ... ::. :.: .::.:. : :.: :::::::.... :: : CCDS45 SFVLITGCANMLLMAALWGLYMSLVNVGHVWYSFGWESQLLETGFLGIFLCPLWTLS--- 140 150 160 170 180 190 160 170 180 190 200 pF1KE0 EAPQGRQAGALPHEDLPFWLVRWLLFRLMFASGVVKLTS-RCPAWWGLTALTYHYETQCL . :: : . .: :::.::.:...:..:. . :: : :: . .::::: . CCDS45 RLPQHT-----PTSRIVLWGFRWLIFRIMLGAGLIKIRGDRC--WRDLTCMDFHYETQPM 200 210 220 230 240 210 220 230 240 250 260 pF1KE0 PTPAAWFAHHLPVWLHKLSVVATFLIEIAVPPLFFAPIRRLRLAAFYSQVLLQVLIIITG :.:.:.. :: : :.:.. .... .::. :: ..: :: . :.:.:...:..: CCDS45 PNPVAYYLHHSPWWFHRFETLSNHFIELLVPFFLFLG-RRACIIHGVLQILFQAVLIVSG 250 260 270 280 290 300 270 280 290 300 310 320 pF1KE0 NYNFFNLMTLVLTTALLDDQHLAAEPGHGSRKKTATSWPKALLATLSLLLELAVYGLLAY : .:.: .:.: . : .:: :::..:. . CCDS45 NLSFLNWLTMVPSLACFDD------------------------ATLGFLFP------SGP 310 320 330 330 340 350 360 370 380 pF1KE0 GTVHYFGLEVDWQQRTIHSRTTFTFHQFSQWLKTLTLPTVWLGVASLVWELLSALWRWTQ :... :.. :: : : . .:.. .. . .: ::: :.: CCDS45 GSLKDRVLQM---QRDI--RGARPEPRFGSVVRRAA--NVSLGVL-LAW----------- 340 350 360 370 390 400 410 420 430 440 pF1KE0 VRGWLRKLSAVVQLSLVGTATVALFLISLVPYSYVEPGTHGRLWTGAHRLFGAVEHLQLA ::. : :.:... : .:: :.. :... CCDS45 -------LSVPVVLNLLSSRQVM--------------NTH----------FNS---LHIV 380 390 400 450 460 470 480 490 500 pF1KE0 NSYGLFRRMTGLGGRPEVVLEGSYDGH------HWTEIEFMYKPGNLSRPPPVVVPHQPR :.:: : .: : ::.:.:. ... : . :: :::. :: : .. :.. : CCDS45 NTYGAFGSITK--ERAEVILQGTASSNASAPDAMWEDYEFKCKPGDPSRRPCLISPYHYR 410 420 430 440 450 460 510 520 530 540 550 560 pF1KE0 LDWQMWFAALGPHTHSPWFTSLVLRLLQGKEPVIRLVQSQVARYPFH-KQPPTYVRAQRY ::: :::::. . :. :. :. .:: . .. :. :. :: . :: .::...: CCDS45 LDWLMWFAAFQTYEHNDWIIHLAGKLLASDAEALSLL----AHNPFAGRPPPRWVRGEHY 470 480 490 500 510 570 580 590 600 610 pF1KE0 KYWFSQPG----EQGQWWRRQWVEEFFPSVSLGDPTLETLLRQFGLQEKSPPRTRSANST .: ::.:: .:.:: :. . .:: .:: . :. .:. : .: CCDS45 RYKFSRPGGRHAAEGKWWVRKRIGAYFPPLSLEE--LRPYFRDRGWPLPGPL 520 530 540 550 560 620 630 640 650 660 670 pF1KE0 LAQALHWTRSQLSPLEAPALLWGLLMAVGAVRFVQALLAPCSLRSSPLAPVSGEKRRPAS 707 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 22:09:26 2016 done: Sat Nov 5 22:09:27 2016 Total Scan time: 3.990 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]