Result of FASTA (omim) for
pF1KE0354
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0354, 719 aa
1>>>pF1KE0354 719 - 719 aa - 719 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4226+/-0.000348; mu= 20.1247+/- 0.022
mean_var=81.6660+/-16.055, 0's: 0 Z-trim(115.3): 121 B-trim: 44 in 1/54
Lambda= 0.141923
statistics sampled from 25582 (25704) to 25582 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.301), width: 16
Scan time: 12.660
The best scores are: opt bits E(85289)
NP_653292 (OMIM: 608839) calpain-12 [Homo sapiens] ( 719) 5003 1034.5 0
XP_016881844 (OMIM: 608839) PREDICTED: calpain-12 ( 723) 4616 955.3 0
XP_016881847 (OMIM: 608839) PREDICTED: calpain-12 ( 698) 4203 870.7 0
XP_016881851 (OMIM: 608839) PREDICTED: calpain-12 ( 590) 4036 836.4 0
XP_016881848 (OMIM: 608839) PREDICTED: calpain-12 ( 676) 3977 824.4 0
XP_016881852 (OMIM: 608839) PREDICTED: calpain-12 ( 565) 3926 813.9 0
XP_016881845 (OMIM: 608839) PREDICTED: calpain-12 ( 702) 3816 791.4 0
XP_016881850 (OMIM: 608839) PREDICTED: calpain-12 ( 604) 3704 768.5 0
XP_016881849 (OMIM: 608839) PREDICTED: calpain-12 ( 652) 3704 768.5 0
XP_016881846 (OMIM: 608839) PREDICTED: calpain-12 ( 699) 3704 768.5 0
XP_016881854 (OMIM: 608839) PREDICTED: calpain-12 ( 503) 3234 672.2 1.4e-192
XP_016881853 (OMIM: 608839) PREDICTED: calpain-12 ( 528) 3144 653.8 5.1e-187
XP_011542588 (OMIM: 114230) PREDICTED: calpain-2 c ( 447) 1374 291.3 5.6e-78
XP_006718761 (OMIM: 114220,616907) PREDICTED: calp ( 714) 1375 291.7 7e-78
NP_001185798 (OMIM: 114220,616907) calpain-1 catal ( 714) 1375 291.7 7e-78
XP_011543594 (OMIM: 114220,616907) PREDICTED: calp ( 714) 1375 291.7 7e-78
NP_005177 (OMIM: 114220,616907) calpain-1 catalyti ( 714) 1375 291.7 7e-78
NP_001185797 (OMIM: 114220,616907) calpain-1 catal ( 714) 1375 291.7 7e-78
NP_001739 (OMIM: 114230) calpain-2 catalytic subun ( 700) 1374 291.4 8e-78
XP_006715050 (OMIM: 604822) PREDICTED: calpain-11 ( 650) 1322 280.8 1.2e-74
XP_006715048 (OMIM: 604822) PREDICTED: calpain-11 ( 724) 1322 280.8 1.3e-74
NP_008989 (OMIM: 604822) calpain-11 [Homo sapiens] ( 739) 1322 280.8 1.3e-74
XP_006715047 (OMIM: 604822) PREDICTED: calpain-11 ( 740) 1322 280.8 1.3e-74
XP_011512577 (OMIM: 604822) PREDICTED: calpain-11 ( 743) 1322 280.8 1.3e-74
XP_011512576 (OMIM: 604822) PREDICTED: calpain-11 ( 744) 1322 280.8 1.3e-74
NP_006606 (OMIM: 606401) calpain-9 isoform 1 [Homo ( 690) 1217 259.3 3.7e-68
XP_011542319 (OMIM: 606401) PREDICTED: calpain-9 i ( 721) 1217 259.3 3.9e-68
NP_775110 (OMIM: 114240,253600) calpain-3 isoform ( 729) 1214 258.7 6e-68
NP_001139540 (OMIM: 114230) calpain-2 catalytic su ( 622) 1143 244.1 1.3e-63
XP_011531165 (OMIM: 610229) PREDICTED: calpain-14 ( 684) 1063 227.8 1.2e-58
NP_001138594 (OMIM: 610229) calpain-14 isoform 1 [ ( 684) 1063 227.8 1.2e-58
XP_011531166 (OMIM: 610229) PREDICTED: calpain-14 ( 684) 1063 227.8 1.2e-58
XP_011531167 (OMIM: 610229) PREDICTED: calpain-14 ( 684) 1063 227.8 1.2e-58
NP_057536 (OMIM: 606401) calpain-9 isoform 2 [Homo ( 664) 908 196.0 4e-49
XP_011542320 (OMIM: 606401) PREDICTED: calpain-9 i ( 695) 908 196.0 4.2e-49
NP_001306605 (OMIM: 606401) calpain-9 isoform 3 [H ( 627) 846 183.3 2.6e-45
XP_011542321 (OMIM: 606401) PREDICTED: calpain-9 i ( 658) 846 183.3 2.7e-45
XP_011531465 (OMIM: 610228) PREDICTED: calpain-13 ( 433) 839 181.7 5.2e-45
XP_016860755 (OMIM: 610228) PREDICTED: calpain-13 ( 665) 839 181.9 7.2e-45
XP_011531463 (OMIM: 610228) PREDICTED: calpain-13 ( 669) 839 181.9 7.3e-45
XP_016860753 (OMIM: 610228) PREDICTED: calpain-13 ( 669) 839 181.9 7.3e-45
XP_011531462 (OMIM: 610228) PREDICTED: calpain-13 ( 669) 839 181.9 7.3e-45
XP_016860754 (OMIM: 610228) PREDICTED: calpain-13 ( 669) 839 181.9 7.3e-45
XP_011531461 (OMIM: 610228) PREDICTED: calpain-13 ( 669) 839 181.9 7.3e-45
NP_653176 (OMIM: 610228) calpain-13 [Homo sapiens] ( 669) 839 181.9 7.3e-45
NP_077320 (OMIM: 114240,253600) calpain-3 isoform ( 815) 733 160.2 2.9e-38
NP_000061 (OMIM: 114240,253600) calpain-3 isoform ( 821) 733 160.2 2.9e-38
XP_016855587 (OMIM: 606401) PREDICTED: calpain-9 i ( 693) 715 156.5 3.3e-37
NP_004046 (OMIM: 193235,602537) calpain-5 [Homo sa ( 640) 601 133.1 3.3e-30
XP_016873712 (OMIM: 193235,602537) PREDICTED: calp ( 676) 601 133.2 3.4e-30
>>NP_653292 (OMIM: 608839) calpain-12 [Homo sapiens] (719 aa)
initn: 5003 init1: 5003 opt: 5003 Z-score: 5533.8 bits: 1034.5 E(85289): 0
Smith-Waterman score: 5003; 100.0% identity (100.0% similar) in 719 aa overlap (1-719:1-719)
10 20 30 40 50 60
pF1KE0 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 LQGPYLPLELGLEQLFQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGLRTCEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 LQGPYLPLELGLEQLFQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGLRTCEQL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 LQCFGHGQSLALHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 LQCFGHGQSLALHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQL
610 620 630 640 650 660
670 680 690 700 710
pF1KE0 TQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWMEVATFS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 TQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWMEVATFS
670 680 690 700 710
>>XP_016881844 (OMIM: 608839) PREDICTED: calpain-12 isof (723 aa)
initn: 4657 init1: 3704 opt: 4616 Z-score: 5105.5 bits: 955.3 E(85289): 0
Smith-Waterman score: 4616; 93.1% identity (94.5% similar) in 725 aa overlap (1-719:1-723)
10 20 30 40 50 60
pF1KE0 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQS
::::::::::::::::::::::::::::::::::::::::::::::: . :
XP_016 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAGDRRRDQRRPAVS
490 500 510 520 530 540
550 560 570 580 590
pF1KE0 LQGPYLPLELGLEQL------FQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGL
: . :. . :.. :: .:. . : .: : :::::::::::::
XP_016 -PGGDCSWRGGMGRGSWPALNFRHAAGPLPAPGAG-VGAAVSGAGWRARAHTSTPREIGL
550 560 570 580 590
600 610 620 630 640 650
pF1KE0 RTCEQLLQCFGHGQSLALHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTCEQLLQCFGHGQSLALHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGF
600 610 620 630 640 650
660 670 680 690 700 710
pF1KE0 HLNNQLTQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLNNQLTQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWME
660 670 680 690 700 710
pF1KE0 VATFS
:::::
XP_016 VATFS
720
>>XP_016881847 (OMIM: 608839) PREDICTED: calpain-12 isof (698 aa)
initn: 4828 init1: 4203 opt: 4203 Z-score: 4648.7 bits: 870.7 E(85289): 0
Smith-Waterman score: 4790; 97.1% identity (97.1% similar) in 719 aa overlap (1-719:1-698)
10 20 30 40 50 60
pF1KE0 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 LQGPYLPLELGLEQLFQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGLRTCEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQGPYLPLELGLEQLFQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGLRTCEQL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 LQCFGHGQSLALHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQL
::::: ::::::::::::::::::::::::::::::::::
XP_016 LQCFG---------------------AIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQL
610 620 630
670 680 690 700 710
pF1KE0 TQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWMEVATFS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWMEVATFS
640 650 660 670 680 690
>>XP_016881851 (OMIM: 608839) PREDICTED: calpain-12 isof (590 aa)
initn: 4036 init1: 4036 opt: 4036 Z-score: 4464.9 bits: 836.4 E(85289): 0
Smith-Waterman score: 4036; 100.0% identity (100.0% similar) in 581 aa overlap (1-581:1-581)
10 20 30 40 50 60
pF1KE0 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 LQGPYLPLELGLEQLFQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGLRTCEQL
:::::::::::::::::::::::::::::::::::::::::
XP_016 LQGPYLPLELGLEQLFQELAGEEEELNASQLQALLSIALEPDWETEVPSG
550 560 570 580 590
610 620 630 640 650 660
pF1KE0 LQCFGHGQSLALHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQL
>>XP_016881848 (OMIM: 608839) PREDICTED: calpain-12 isof (676 aa)
initn: 4018 init1: 3704 opt: 3977 Z-score: 4398.8 bits: 824.4 E(85289): 0
Smith-Waterman score: 3977; 92.1% identity (93.7% similar) in 632 aa overlap (1-626:1-630)
10 20 30 40 50 60
pF1KE0 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQS
::::::::::::::::::::::::::::::::::::::::::::::: . :
XP_016 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAGDRRRDQRRPAVS
490 500 510 520 530 540
550 560 570 580 590
pF1KE0 LQGPYLPLELGLEQL------FQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGL
: . :. . :.. :: .:. . : .: : :::::::::::::
XP_016 -PGGDCSWRGGMGRGSWPALNFRHAAGPLPAPGAG-VGAAVSGAGWRARAHTSTPREIGL
550 560 570 580 590
600 610 620 630 640 650
pF1KE0 RTCEQLLQCFGHGQSLALHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGF
::::::::::::::::::::::::::::::::
XP_016 RTCEQLLQCFGHGQSLALHHFQQLWGYLLEWQIGKQKSQVARLLAGGPHQKKGSWDGHQA
600 610 620 630 640 650
660 670 680 690 700 710
pF1KE0 HLNNQLTQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWME
XP_016 VLPGRPHWQPSSGHGGQP
660 670
>>XP_016881852 (OMIM: 608839) PREDICTED: calpain-12 isof (565 aa)
initn: 3926 init1: 3926 opt: 3926 Z-score: 4343.5 bits: 813.9 E(85289): 0
Smith-Waterman score: 3926; 100.0% identity (100.0% similar) in 562 aa overlap (1-562:1-562)
10 20 30 40 50 60
pF1KE0 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 LQGPYLPLELGLEQLFQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGLRTCEQL
::::::::::::::::::::::
XP_016 LQGPYLPLELGLEQLFQELAGEAST
550 560
>>XP_016881845 (OMIM: 608839) PREDICTED: calpain-12 isof (702 aa)
initn: 4482 init1: 3704 opt: 3816 Z-score: 4220.4 bits: 791.4 E(85289): 0
Smith-Waterman score: 4403; 90.2% identity (91.6% similar) in 725 aa overlap (1-719:1-702)
10 20 30 40 50 60
pF1KE0 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQS
::::::::::::::::::::::::::::::::::::::::::::::: . :
XP_016 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAGDRRRDQRRPAVS
490 500 510 520 530 540
550 560 570 580 590
pF1KE0 LQGPYLPLELGLEQL------FQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGL
: . :. . :.. :: .:. . : .: : :::::::::::::
XP_016 -PGGDCSWRGGMGRGSWPALNFRHAAGPLPAPGAG-VGAAVSGAGWRARAHTSTPREIGL
550 560 570 580 590
600 610 620 630 640 650
pF1KE0 RTCEQLLQCFGHGQSLALHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGF
::::::::::: ::::::::::::::::::::::::::::
XP_016 RTCEQLLQCFG---------------------AIFNKFDEDTSGTMNSYELRLALNAAGF
600 610 620 630
660 670 680 690 700 710
pF1KE0 HLNNQLTQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLNNQLTQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWME
640 650 660 670 680 690
pF1KE0 VATFS
:::::
XP_016 VATFS
700
>>XP_016881850 (OMIM: 608839) PREDICTED: calpain-12 isof (604 aa)
initn: 3704 init1: 3704 opt: 3704 Z-score: 4097.4 bits: 768.5 E(85289): 0
Smith-Waterman score: 3704; 100.0% identity (100.0% similar) in 527 aa overlap (1-527:1-527)
10 20 30 40 50 60
pF1KE0 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQS
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAGDRRRDQRRPAVS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 LQGPYLPLELGLEQLFQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGLRTCEQL
XP_016 PGGDCSWRGGMGRGSWPALNFRHAAGPLPAPGAGVGAAVSGAGWRGGRTQCLSAPGLTKH
550 560 570 580 590 600
>>XP_016881849 (OMIM: 608839) PREDICTED: calpain-12 isof (652 aa)
initn: 4168 init1: 3704 opt: 3704 Z-score: 4096.9 bits: 768.5 E(85289): 0
Smith-Waterman score: 4031; 84.6% identity (86.9% similar) in 719 aa overlap (1-719:1-652)
10 20 30 40 50 60
pF1KE0 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQS
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTA-------------
490 500 510 520
550 560 570 580 590 600
pF1KE0 LQGPYLPLELGLEQLFQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGLRTCEQL
:.... . : .: . . :
XP_016 --------------------GDRRR--------------DQRRPAVSPGGDCSWRGG---
530 540 550
610 620 630 640 650 660
pF1KE0 LQCFGHGQSLALHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQL
.:.:. ::. :.. : : : .::. . ::::::::
XP_016 ---MGRGSWPALN-FRHAAGPL---PAPGAGVGAAVSGA----------GWRGFHLNNQL
560 570 580 590
670 680 690 700 710
pF1KE0 TQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWMEVATFS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWMEVATFS
600 610 620 630 640 650
>>XP_016881846 (OMIM: 608839) PREDICTED: calpain-12 isof (699 aa)
initn: 4657 init1: 3704 opt: 3704 Z-score: 4096.5 bits: 768.5 E(85289): 0
Smith-Waterman score: 4609; 94.0% identity (94.4% similar) in 719 aa overlap (1-719:1-699)
10 20 30 40 50 60
pF1KE0 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQS
::::::::::::::::::::::::::::::::::::::::::::::: . :
XP_016 SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAGDRRRDQRRPAVS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 LQGPYLPLELGLEQLFQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGLRTCEQL
:: :: : :: . : .: : :::::::::::::::::::
XP_016 -PGP-LPAP-G--------AG---------VGAAVSGAGWRARAHTSTPREIGLRTCEQL
550 560 570 580
610 620 630 640 650 660
pF1KE0 LQCFGHGQSLALHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQCFGHGQSLALHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQL
590 600 610 620 630 640
670 680 690 700 710
pF1KE0 TQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWMEVATFS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWMEVATFS
650 660 670 680 690
719 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 12:01:41 2016 done: Sat Nov 5 12:01:43 2016
Total Scan time: 12.660 Total Display time: 0.190
Function used was FASTA [36.3.4 Apr, 2011]