FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0357, 601 aa 1>>>pF1KE0357 601 - 601 aa - 601 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4580+/-0.000405; mu= 13.9631+/- 0.025 mean_var=101.4001+/-20.517, 0's: 0 Z-trim(113.0): 33 B-trim: 209 in 1/56 Lambda= 0.127366 statistics sampled from 22178 (22201) to 22178 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.26), width: 16 Scan time: 9.200 The best scores are: opt bits E(85289) XP_011542723 (OMIM: 268300,269000,609353) PREDICTE ( 601) 3999 745.9 8.9e-215 NP_001017420 (OMIM: 268300,269000,609353) N-acetyl ( 601) 3999 745.9 8.9e-215 XP_011542724 (OMIM: 268300,269000,609353) PREDICTE ( 591) 3854 719.2 9.2e-207 NP_443143 (OMIM: 609674) N-acetyltransferase ESCO1 ( 840) 1055 205.0 8.3e-52 XP_011524100 (OMIM: 609674) PREDICTED: N-acetyltra ( 840) 1055 205.0 8.3e-52 XP_011524101 (OMIM: 609674) PREDICTED: N-acetyltra ( 810) 642 129.1 5.6e-29 >>XP_011542723 (OMIM: 268300,269000,609353) PREDICTED: N (601 aa) initn: 3999 init1: 3999 opt: 3999 Z-score: 3976.9 bits: 745.9 E(85289): 8.9e-215 Smith-Waterman score: 3999; 100.0% identity (100.0% similar) in 601 aa overlap (1-601:1-601) 10 20 30 40 50 60 pF1KE0 MAALTPRKRKQDSLKCDSLLHFTENLFPSPNKKHCFYQNSDKNEENLHCSQQEHFVLSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAALTPRKRKQDSLKCDSLLHFTENLFPSPNKKHCFYQNSDKNEENLHCSQQEHFVLSAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KTTEINRLPSANQGSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTTEINRLPSANQGSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IVTEKMQGKPVCSKKNNKKPQKSLTAKYQPKYRHIKPVSRNSRNSKQNRVIYKPIVEKEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVTEKMQGKPVCSKKNNKKPQKSLTAKYQPKYRHIKPVSRNSRNSKQNRVIYKPIVEKEN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 NCHSAENNSNAPRVLSQKIKPQVTLQGGAAFFVRKKSSLRKSSLENEPSLGRTQKSKSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NCHSAENNSNAPRVLSQKIKPQVTLQGGAAFFVRKKSSLRKSSLENEPSLGRTQKSKSEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 IEDSDVETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDRVSSKEHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IEDSDVETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDRVSSKEHK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 VDKNEAFSSEDSLGENKTISPKSTVYPIFSASSVNSKRSLGEEQFSVGSVNFMKQTNIQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDKNEAFSSEDSLGENKTISPKSTVYPIFSASSVNSKRSLGEEQFSVGSVNFMKQTNIQK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 NTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHHHRFLEGIKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHHHRFLEGIKY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 VGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQVVPKCPNKIKTFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQVVPKCPNKIKTFL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 FISDEKRVVGCLIAEPIKQAFRVLSEPIGPESPSSTECPRAWQCSDVPEPAVCGISRIWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FISDEKRVVGCLIAEPIKQAFRVLSEPIGPESPSSTECPRAWQCSDVPEPAVCGISRIWV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 FRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLFATKYCNTPNFLVYNFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLFATKYCNTPNFLVYNFN 550 560 570 580 590 600 pF1KE0 S : XP_011 S >>NP_001017420 (OMIM: 268300,269000,609353) N-acetyltran (601 aa) initn: 3999 init1: 3999 opt: 3999 Z-score: 3976.9 bits: 745.9 E(85289): 8.9e-215 Smith-Waterman score: 3999; 100.0% identity (100.0% similar) in 601 aa overlap (1-601:1-601) 10 20 30 40 50 60 pF1KE0 MAALTPRKRKQDSLKCDSLLHFTENLFPSPNKKHCFYQNSDKNEENLHCSQQEHFVLSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAALTPRKRKQDSLKCDSLLHFTENLFPSPNKKHCFYQNSDKNEENLHCSQQEHFVLSAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KTTEINRLPSANQGSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTTEINRLPSANQGSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IVTEKMQGKPVCSKKNNKKPQKSLTAKYQPKYRHIKPVSRNSRNSKQNRVIYKPIVEKEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVTEKMQGKPVCSKKNNKKPQKSLTAKYQPKYRHIKPVSRNSRNSKQNRVIYKPIVEKEN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 NCHSAENNSNAPRVLSQKIKPQVTLQGGAAFFVRKKSSLRKSSLENEPSLGRTQKSKSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NCHSAENNSNAPRVLSQKIKPQVTLQGGAAFFVRKKSSLRKSSLENEPSLGRTQKSKSEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 IEDSDVETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDRVSSKEHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEDSDVETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDRVSSKEHK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 VDKNEAFSSEDSLGENKTISPKSTVYPIFSASSVNSKRSLGEEQFSVGSVNFMKQTNIQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDKNEAFSSEDSLGENKTISPKSTVYPIFSASSVNSKRSLGEEQFSVGSVNFMKQTNIQK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 NTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHHHRFLEGIKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHHHRFLEGIKY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 VGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQVVPKCPNKIKTFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQVVPKCPNKIKTFL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 FISDEKRVVGCLIAEPIKQAFRVLSEPIGPESPSSTECPRAWQCSDVPEPAVCGISRIWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FISDEKRVVGCLIAEPIKQAFRVLSEPIGPESPSSTECPRAWQCSDVPEPAVCGISRIWV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 FRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLFATKYCNTPNFLVYNFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLFATKYCNTPNFLVYNFN 550 560 570 580 590 600 pF1KE0 S : NP_001 S >>XP_011542724 (OMIM: 268300,269000,609353) PREDICTED: N (591 aa) initn: 3853 init1: 3853 opt: 3854 Z-score: 3833.0 bits: 719.2 E(85289): 9.2e-207 Smith-Waterman score: 3854; 98.5% identity (99.0% similar) in 591 aa overlap (1-591:1-591) 10 20 30 40 50 60 pF1KE0 MAALTPRKRKQDSLKCDSLLHFTENLFPSPNKKHCFYQNSDKNEENLHCSQQEHFVLSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAALTPRKRKQDSLKCDSLLHFTENLFPSPNKKHCFYQNSDKNEENLHCSQQEHFVLSAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KTTEINRLPSANQGSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTTEINRLPSANQGSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IVTEKMQGKPVCSKKNNKKPQKSLTAKYQPKYRHIKPVSRNSRNSKQNRVIYKPIVEKEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVTEKMQGKPVCSKKNNKKPQKSLTAKYQPKYRHIKPVSRNSRNSKQNRVIYKPIVEKEN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 NCHSAENNSNAPRVLSQKIKPQVTLQGGAAFFVRKKSSLRKSSLENEPSLGRTQKSKSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NCHSAENNSNAPRVLSQKIKPQVTLQGGAAFFVRKKSSLRKSSLENEPSLGRTQKSKSEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 IEDSDVETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDRVSSKEHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IEDSDVETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDRVSSKEHK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 VDKNEAFSSEDSLGENKTISPKSTVYPIFSASSVNSKRSLGEEQFSVGSVNFMKQTNIQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDKNEAFSSEDSLGENKTISPKSTVYPIFSASSVNSKRSLGEEQFSVGSVNFMKQTNIQK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 NTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHHHRFLEGIKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHHHRFLEGIKY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 VGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQVVPKCPNKIKTFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQVVPKCPNKIKTFL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 FISDEKRVVGCLIAEPIKQAFRVLSEPIGPESPSSTECPRAWQCSDVPEPAVCGISRIWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FISDEKRVVGCLIAEPIKQAFRVLSEPIGPESPSSTECPRAWQCSDVPEPAVCGISRIWV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 FRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLFATKYCNTPNFLVYNFN :::::::::::::::::::::::::::::::::::::::: ..: .: XP_011 FRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDDCRRLNRYQET 550 560 570 580 590 pF1KE0 S >>NP_443143 (OMIM: 609674) N-acetyltransferase ESCO1 [Ho (840 aa) initn: 1000 init1: 602 opt: 1055 Z-score: 1051.1 bits: 205.0 E(85289): 8.3e-52 Smith-Waterman score: 1068; 37.9% identity (66.9% similar) in 525 aa overlap (104-599:322-833) 80 90 100 110 120 130 pF1KE0 GSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFPIVTEK--MQGKPV ...:. ... :.: : :. .. . . NP_443 LEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQIL 300 310 320 330 340 350 140 150 160 170 180 pF1KE0 CSKKNNKKPQKSLTAKYQPKYRHIKPVS--RNSRNS--KQNRVIYKPIVEKENNC-HSAE .:..:. : .. :. :. :::. :. :: :.: : . : :. :. NP_443 HQKETNQDVQ---CNRFFPS-RKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKL 360 370 380 390 400 190 200 210 220 230 240 pF1KE0 NNSNAPRV--LSQKIKPQVTLQGGA---AFFVRKKSSLRKSSLENEPSLGRTQKSKSEVI ... .:.. : ...: . . . :. : :. . ..: . .. .:: . NP_443 DSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQE----KMKEINSEEV 410 420 430 440 450 460 250 260 270 280 290 pF1KE0 EDSDV--------ETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDR . .:. : . :. .:.. :. :....: .. :::.:: . .... .. NP_443 KINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLEN- 470 480 490 500 510 520 300 310 320 330 340 pF1KE0 VSSKEHKVDKNEAFSSEDSL--GENKTISPKSTVYPIFSASSVNSKRSLGEE---QFSVG : ..: .. :. .. :::: . . :.: .. :: : ..: . :. NP_443 --SPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQT--SKSSDNRETPRNHSLP 530 540 550 560 570 350 360 370 380 390 400 pF1KE0 SVNFMKQTNIQKNTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHV . : . .: :. . ... : . :::::::::.:::. :. :::.::::::::: ::. NP_443 KCNSHLEITIPKDLKLKEAEKTDEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHL 580 590 600 610 620 630 410 420 430 440 450 460 pF1KE0 QHHHRFLEGIKYVGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQV :..:. ..:::::::::..::. ::.:..:::.::..:.:::....:.:::.:::::. NP_443 LFHNQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQA 640 650 660 670 680 690 470 480 490 500 510 520 pF1KE0 VPKCPNKIKTFLFISDEKRVVGCLIAEPIKQAFRVLSE--PI--GPESPSSTECPRAWQC : .. ::.::::..:.:::::::: :. ..::. : :. . : : .:: : NP_443 PLMCYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCC 700 710 720 730 740 750 530 540 550 560 570 580 pF1KE0 SDVPEPAVCGISRIWVFRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLF : .::::.::::::::: . :::.:: :... ::. :..: .:: .:::::::::::::: NP_443 STLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLF 760 770 780 790 800 810 590 600 pF1KE0 ATKYCNTPNFLVYNFNS ::.::.: .:::::: NP_443 ATQYCGTGQFLVYNFINGQNST 820 830 840 >>XP_011524100 (OMIM: 609674) PREDICTED: N-acetyltransfe (840 aa) initn: 1000 init1: 602 opt: 1055 Z-score: 1051.1 bits: 205.0 E(85289): 8.3e-52 Smith-Waterman score: 1068; 37.9% identity (66.9% similar) in 525 aa overlap (104-599:322-833) 80 90 100 110 120 130 pF1KE0 GSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFPIVTEK--MQGKPV ...:. ... :.: : :. .. . . XP_011 LEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQIL 300 310 320 330 340 350 140 150 160 170 180 pF1KE0 CSKKNNKKPQKSLTAKYQPKYRHIKPVS--RNSRNS--KQNRVIYKPIVEKENNC-HSAE .:..:. : .. :. :. :::. :. :: :.: : . : :. :. XP_011 HQKETNQDVQ---CNRFFPS-RKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKL 360 370 380 390 400 190 200 210 220 230 240 pF1KE0 NNSNAPRV--LSQKIKPQVTLQGGA---AFFVRKKSSLRKSSLENEPSLGRTQKSKSEVI ... .:.. : ...: . . . :. : :. . ..: . .. .:: . XP_011 DSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQE----KMKEINSEEV 410 420 430 440 450 460 250 260 270 280 290 pF1KE0 EDSDV--------ETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDR . .:. : . :. .:.. :. :....: .. :::.:: . .... .. XP_011 KINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLEN- 470 480 490 500 510 520 300 310 320 330 340 pF1KE0 VSSKEHKVDKNEAFSSEDSL--GENKTISPKSTVYPIFSASSVNSKRSLGEE---QFSVG : ..: .. :. .. :::: . . :.: .. :: : ..: . :. XP_011 --SPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQT--SKSSDNRETPRNHSLP 530 540 550 560 570 350 360 370 380 390 400 pF1KE0 SVNFMKQTNIQKNTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHV . : . .: :. . ... : . :::::::::.:::. :. :::.::::::::: ::. XP_011 KCNSHLEITIPKDLKLKEAEKTDEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHL 580 590 600 610 620 630 410 420 430 440 450 460 pF1KE0 QHHHRFLEGIKYVGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQV :..:. ..:::::::::..::. ::.:..:::.::..:.:::....:.:::.:::::. XP_011 LFHNQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQA 640 650 660 670 680 690 470 480 490 500 510 520 pF1KE0 VPKCPNKIKTFLFISDEKRVVGCLIAEPIKQAFRVLSE--PI--GPESPSSTECPRAWQC : .. ::.::::..:.:::::::: :. ..::. : :. . : : .:: : XP_011 PLMCYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCC 700 710 720 730 740 750 530 540 550 560 570 580 pF1KE0 SDVPEPAVCGISRIWVFRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLF : .::::.::::::::: . :::.:: :... ::. :..: .:: .:::::::::::::: XP_011 STLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLF 760 770 780 790 800 810 590 600 pF1KE0 ATKYCNTPNFLVYNFNS ::.::.: .:::::: XP_011 ATQYCGTGQFLVYNFINGQNST 820 830 840 >>XP_011524101 (OMIM: 609674) PREDICTED: N-acetyltransfe (810 aa) initn: 826 init1: 412 opt: 642 Z-score: 641.2 bits: 129.1 E(85289): 5.6e-29 Smith-Waterman score: 842; 34.3% identity (61.3% similar) in 525 aa overlap (104-599:322-803) 80 90 100 110 120 130 pF1KE0 GSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFPIVTEK--MQGKPV ...:. ... :.: : :. .. . . XP_011 LEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQIL 300 310 320 330 340 350 140 150 160 170 180 pF1KE0 CSKKNNKKPQKSLTAKYQPKYRHIKPVS--RNSRNS--KQNRVIYKPIVEKENNC-HSAE .:..:. : .. :. :. :::. :. :: :.: : . : :. :. XP_011 HQKETNQDVQ---CNRFFPS-RKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKL 360 370 380 390 400 190 200 210 220 230 240 pF1KE0 NNSNAPRV--LSQKIKPQVTLQGGA---AFFVRKKSSLRKSSLENEPSLGRTQKSKSEVI ... .:.. : ...: . . . :. : :. . ..: . .. .:: . XP_011 DSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQE----KMKEINSEEV 410 420 430 440 450 460 250 260 270 280 290 pF1KE0 EDSDV--------ETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDR . .:. : . :. .:.. :. :....: .. :::.:: . .... .. XP_011 KINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLEN- 470 480 490 500 510 520 300 310 320 330 340 pF1KE0 VSSKEHKVDKNEAFSSEDSL--GENKTISPKSTVYPIFSASSVNSKRSLGEE---QFSVG : ..: .. :. .. :::: . . :.: .. :: : ..: . :. XP_011 --SPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQT--SKSSDNRETPRNHSLP 530 540 550 560 570 350 360 370 380 390 400 pF1KE0 SVNFMKQTNIQKNTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHV . : . .: :. . ... : . :::::::::.:::. :. :::.::::::::: ::. XP_011 KCNSHLEITIPKDLKLKEAEKTDEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHL 580 590 600 610 620 630 410 420 430 440 450 460 pF1KE0 QHHHRFLEGIKYVGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQV :..:. ..::: :....:.:::.:::::. XP_011 LFHNQFISAVKYV------------------------------VDEIREMVDNDLGFQQA 640 650 660 470 480 490 500 510 520 pF1KE0 VPKCPNKIKTFLFISDEKRVVGCLIAEPIKQAFRVLSE--PI--GPESPSSTECPRAWQC : .. ::.::::..:.:::::::: :. ..::. : :. . : : .:: : XP_011 PLMCYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCC 670 680 690 700 710 720 530 540 550 560 570 580 pF1KE0 SDVPEPAVCGISRIWVFRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLF : .::::.::::::::: . :::.:: :... ::. :..: .:: .:::::::::::::: XP_011 STLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLF 730 740 750 760 770 780 590 600 pF1KE0 ATKYCNTPNFLVYNFNS ::.::.: .:::::: XP_011 ATQYCGTGQFLVYNFINGQNST 790 800 810 601 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:19:07 2016 done: Thu Nov 3 14:19:08 2016 Total Scan time: 9.200 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]