Result of FASTA (omim) for
pF1KE0364
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0364, 690 aa
1>>>pF1KE0364 690 - 690 aa - 690 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9831+/-0.000381; mu= 22.4792+/- 0.024
mean_var=81.9977+/-16.877, 0's: 0 Z-trim(114.0): 121 B-trim: 36 in 1/52
Lambda= 0.141636
statistics sampled from 23519 (23649) to 23519 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.635), E-opt: 0.2 (0.277), width: 16
Scan time: 11.300
The best scores are: opt bits E(85289)
NP_036386 (OMIM: 603314) bile acyl-CoA synthetase ( 690) 4726 976.0 0
XP_011524666 (OMIM: 603314) PREDICTED: bile acyl-C ( 606) 4048 837.4 0
NP_001308125 (OMIM: 603314) bile acyl-CoA syntheta ( 606) 3167 657.4 4.6e-188
XP_016881703 (OMIM: 603314) PREDICTED: bile acyl-C ( 395) 2698 561.4 2.4e-159
NP_003636 (OMIM: 603247) very long-chain acyl-CoA ( 620) 1819 381.9 3.9e-105
NP_054750 (OMIM: 604196) long-chain fatty acid tra ( 619) 1637 344.7 6e-94
NP_001017372 (OMIM: 604196) long-chain fatty acid ( 619) 1637 344.7 6e-94
NP_001304913 (OMIM: 604196) long-chain fatty acid ( 619) 1637 344.7 6e-94
NP_077306 (OMIM: 604193) long-chain fatty acid tra ( 730) 1629 343.2 2.1e-93
NP_001304858 (OMIM: 604193) long-chain fatty acid ( 695) 1483 313.3 1.9e-84
XP_011526305 (OMIM: 600691) PREDICTED: long-chain ( 646) 1306 277.1 1.4e-73
NP_940982 (OMIM: 600691) long-chain fatty acid tra ( 646) 1306 277.1 1.4e-73
NP_001153101 (OMIM: 603247) very long-chain acyl-C ( 567) 1283 272.4 3.4e-72
XP_016869711 (OMIM: 604194,608649) PREDICTED: long ( 643) 1283 272.4 3.7e-72
NP_005085 (OMIM: 604194,608649) long-chain fatty a ( 643) 1283 272.4 3.7e-72
XP_011526304 (OMIM: 600691) PREDICTED: long-chain ( 658) 917 197.7 1.2e-49
XP_016882270 (OMIM: 600691) PREDICTED: long-chain ( 658) 917 197.7 1.2e-49
XP_011526302 (OMIM: 600691) PREDICTED: long-chain ( 658) 917 197.7 1.2e-49
XP_011526303 (OMIM: 600691) PREDICTED: long-chain ( 658) 917 197.7 1.2e-49
XP_016878510 (OMIM: 614245,614265) PREDICTED: acyl ( 463) 242 59.6 3.2e-08
XP_016878508 (OMIM: 614245,614265) PREDICTED: acyl ( 555) 242 59.7 3.6e-08
NP_777577 (OMIM: 614245,614265) acyl-CoA synthetas ( 576) 242 59.7 3.7e-08
NP_001120686 (OMIM: 614245,614265) acyl-CoA synthe ( 576) 242 59.7 3.7e-08
NP_001230208 (OMIM: 614245,614265) acyl-CoA synthe ( 576) 242 59.7 3.7e-08
XP_011521244 (OMIM: 614245,614265) PREDICTED: acyl ( 610) 242 59.7 3.9e-08
XP_005256350 (OMIM: 614245,614265) PREDICTED: acyl ( 610) 242 59.7 3.9e-08
XP_011521245 (OMIM: 614245,614265) PREDICTED: acyl ( 610) 242 59.7 3.9e-08
XP_016878507 (OMIM: 614245,614265) PREDICTED: acyl ( 610) 242 59.7 3.9e-08
XP_006723889 (OMIM: 605832) PREDICTED: acetyl-coen ( 629) 230 57.3 2.2e-07
XP_011527214 (OMIM: 605832) PREDICTED: acetyl-coen ( 642) 230 57.3 2.2e-07
XP_011527213 (OMIM: 605832) PREDICTED: acetyl-coen ( 674) 230 57.3 2.3e-07
XP_011527211 (OMIM: 605832) PREDICTED: acetyl-coen ( 687) 230 57.3 2.3e-07
XP_005260513 (OMIM: 605832) PREDICTED: acetyl-coen ( 711) 230 57.3 2.3e-07
XP_011527209 (OMIM: 605832) PREDICTED: acetyl-coen ( 724) 230 57.3 2.4e-07
XP_005260512 (OMIM: 605832) PREDICTED: acetyl-coen ( 724) 230 57.3 2.4e-07
XP_011527207 (OMIM: 605832) PREDICTED: acetyl-coen ( 737) 230 57.3 2.4e-07
XP_011523596 (OMIM: 610465) PREDICTED: acyl-CoA sy ( 609) 186 48.2 0.00011
XP_006722173 (OMIM: 610465) PREDICTED: acyl-CoA sy ( 445) 183 47.5 0.00013
NP_001229322 (OMIM: 605832) acetyl-coenzyme A synt ( 606) 178 46.6 0.00033
NP_061147 (OMIM: 605832) acetyl-coenzyme A synthet ( 701) 178 46.7 0.00037
NP_001070020 (OMIM: 605832) acetyl-coenzyme A synt ( 714) 178 46.7 0.00037
XP_011527210 (OMIM: 605832) PREDICTED: acetyl-coen ( 714) 178 46.7 0.00037
XP_011527208 (OMIM: 605832) PREDICTED: acetyl-coen ( 727) 178 46.7 0.00038
XP_016878404 (OMIM: 614357) PREDICTED: acyl-coenzy ( 339) 169 44.5 0.00079
XP_006721081 (OMIM: 614357) PREDICTED: acyl-coenzy ( 357) 169 44.5 0.00082
XP_011544034 (OMIM: 614357) PREDICTED: acyl-coenzy ( 357) 169 44.5 0.00082
XP_011544033 (OMIM: 614357) PREDICTED: acyl-coenzy ( 378) 169 44.6 0.00085
NP_001305819 (OMIM: 614357) acyl-coenzyme A synthe ( 577) 169 44.8 0.0011
NP_443188 (OMIM: 614357) acyl-coenzyme A synthetas ( 577) 169 44.8 0.0011
NP_115890 (OMIM: 614355) acetyl-coenzyme A synthet ( 689) 158 42.6 0.0062
>>NP_036386 (OMIM: 603314) bile acyl-CoA synthetase isof (690 aa)
initn: 4726 init1: 4726 opt: 4726 Z-score: 5218.3 bits: 976.0 E(85289): 0
Smith-Waterman score: 4726; 100.0% identity (100.0% similar) in 690 aa overlap (1-690:1-690)
10 20 30 40 50 60
pF1KE0 MGVRQQLALLLLLLLLLWGLGQPVWPVAVALTLRWLLGDPTCCVLLGLAMLARPWLGPWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MGVRQQLALLLLLLLLLWGLGQPVWPVAVALTLRWLLGDPTCCVLLGLAMLARPWLGPWV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PHGLSLAAAALALTLLPARLPPGLRWLPADVIFLAKILHLGLKIRGCLSRQPPDTFVDAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PHGLSLAAAALALTLLPARLPPGLRWLPADVIFLAKILHLGLKIRGCLSRQPPDTFVDAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ERRARAQPGRALLVWTGPGAGSVTFGELDARACQAAWALKAELGDPASLCAGEPTALLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ERRARAQPGRALLVWTGPGAGSVTFGELDARACQAAWALKAELGDPASLCAGEPTALLVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LPKPAILTHERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LPKPAILTHERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 KFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRADVWETFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRADVWETFQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 QRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 QGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 REGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 REGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 LAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRLVREGFNVGIVVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRLVREGFNVGIVVD
610 620 630 640 650 660
670 680 690
pF1KE0 PLFVLDNRAQSFRPLTAEMYQAVCEGTWRL
::::::::::::::::::::::::::::::
NP_036 PLFVLDNRAQSFRPLTAEMYQAVCEGTWRL
670 680 690
>>XP_011524666 (OMIM: 603314) PREDICTED: bile acyl-CoA s (606 aa)
initn: 4072 init1: 4046 opt: 4048 Z-score: 4470.2 bits: 837.4 E(85289): 0
Smith-Waterman score: 4048; 98.8% identity (99.0% similar) in 600 aa overlap (1-600:1-598)
10 20 30 40 50 60
pF1KE0 MGVRQQLALLLLLLLLLWGLGQPVWPVAVALTLRWLLGDPTCCVLLGLAMLARPWLGPWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGVRQQLALLLLLLLLLWGLGQPVWPVAVALTLRWLLGDPTCCVLLGLAMLARPWLGPWV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PHGLSLAAAALALTLLPARLPPGLRWLPADVIFLAKILHLGLKIRGCLSRQPPDTFVDAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHGLSLAAAALALTLLPARLPPGLRWLPADVIFLAKILHLGLKIRGCLSRQPPDTFVDAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ERRARAQPGRALLVWTGPGAGSVTFGELDARACQAAWALKAELGDPASLCAGEPTALLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERRARAQPGRALLVWTGPGAGSVTFGELDARACQAAWALKAELGDPASLCAGEPTALLVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LPKPAILTHERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPKPAILTHERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 KFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRADVWETFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRADVWETFQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 QRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 QGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 REGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQ
::::::::::::::::::::::::::::::::::::::::::::::::: .: : ::
XP_011 REGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGRHG--GHQHVQ
550 560 570 580 590
610 620 630 640 650 660
pF1KE0 LAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRLVREGFNVGIVVD
XP_011 TDEDPVGA
600
>>NP_001308125 (OMIM: 603314) bile acyl-CoA synthetase i (606 aa)
initn: 4131 init1: 3141 opt: 3167 Z-score: 3497.3 bits: 657.4 E(85289): 4.6e-188
Smith-Waterman score: 3967; 87.8% identity (87.8% similar) in 690 aa overlap (1-690:1-606)
10 20 30 40 50 60
pF1KE0 MGVRQQLALLLLLLLLLWGLGQPVWPVAVALTLRWLLGDPTCCVLLGLAMLARPWLGPWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGVRQQLALLLLLLLLLWGLGQPVWPVAVALTLRWLLGDPTCCVLLGLAMLARPWLGPWV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PHGLSLAAAALALTLLPARLPPGLRWLPADVIFLAKILHLGLKIRGCLSRQPPDTFVDAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHGLSLAAAALALTLLPARLPPGLRWLPADVIFLAKILHLGLKIRGCLSRQPPDTFVDAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ERRARAQPGRALLVWTGPGAGSVTFGELDARACQAAWALKAELGDPASLCAGEPTALLVL
:::::::::::::::::::::::::
NP_001 ERRARAQPGRALLVWTGPGAGSVTF-----------------------------------
130 140
190 200 210 220 230 240
pF1KE0 ASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILP
:::::::::::
NP_001 -------------------------------------------------DLRESLEEILP
150
250 260 270 280 290 300
pF1KE0 KLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTG
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE0 LPKPAILTHERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPKPAILTHERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAP
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE0 KFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRADVWETFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRADVWETFQ
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE0 QRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDN
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE0 QGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMD
400 410 420 430 440 450
550 560 570 580 590 600
pF1KE0 REGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQ
460 470 480 490 500 510
610 620 630 640 650 660
pF1KE0 LAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRLVREGFNVGIVVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRLVREGFNVGIVVD
520 530 540 550 560 570
670 680 690
pF1KE0 PLFVLDNRAQSFRPLTAEMYQAVCEGTWRL
::::::::::::::::::::::::::::::
NP_001 PLFVLDNRAQSFRPLTAEMYQAVCEGTWRL
580 590 600
>>XP_016881703 (OMIM: 603314) PREDICTED: bile acyl-CoA s (395 aa)
initn: 2698 init1: 2698 opt: 2698 Z-score: 2981.8 bits: 561.4 E(85289): 2.4e-159
Smith-Waterman score: 2698; 100.0% identity (100.0% similar) in 394 aa overlap (1-394:1-394)
10 20 30 40 50 60
pF1KE0 MGVRQQLALLLLLLLLLWGLGQPVWPVAVALTLRWLLGDPTCCVLLGLAMLARPWLGPWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGVRQQLALLLLLLLLLWGLGQPVWPVAVALTLRWLLGDPTCCVLLGLAMLARPWLGPWV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PHGLSLAAAALALTLLPARLPPGLRWLPADVIFLAKILHLGLKIRGCLSRQPPDTFVDAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHGLSLAAAALALTLLPARLPPGLRWLPADVIFLAKILHLGLKIRGCLSRQPPDTFVDAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ERRARAQPGRALLVWTGPGAGSVTFGELDARACQAAWALKAELGDPASLCAGEPTALLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRARAQPGRALLVWTGPGAGSVTFGELDARACQAAWALKAELGDPASLCAGEPTALLVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LPKPAILTHERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPKPAILTHERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 KFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRADVWETFQ
::::::::::::::::::::::::::::::::::
XP_016 KFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQF
370 380 390
430 440 450 460 470 480
pF1KE0 QRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDN
>>NP_003636 (OMIM: 603247) very long-chain acyl-CoA synt (620 aa)
initn: 1775 init1: 1775 opt: 1819 Z-score: 2008.6 bits: 381.9 E(85289): 3.9e-105
Smith-Waterman score: 1893; 45.0% identity (74.2% similar) in 629 aa overlap (64-690:2-620)
40 50 60 70 80 90
pF1KE0 RWLLGDPTCCVLLGLAMLARPWLGPWVPHGLSLAAAALA-LTLLPARLPPGLRWLPADVI
:: ..:: : .:: . .. :.
NP_003 MLSAIYTVLAGLLFLPLLVNLCCPYFFQDIG
10 20 30
100 110 120 130 140 150
pF1KE0 FLAKILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELDARA
.. :. .: ..:. .:.: :.. :: ..:: : . .:.. ..:....: :.
NP_003 YFLKVAAVGRRVRSYGKRRPARTILRAFLEKARQTPHKPFLLFRDE---TLTYAQVDRRS
40 50 60 70 80
160 170 180 190 200 210
pF1KE0 CQAAWALKAELGDPASLCAGEPTALLVLASQAVPALC-MWLGLAKLGCPTAWINPHGRGM
:.: ::. .:: : :. .::: .... :: .::::.:::: : .: . :.
NP_003 NQVARALHDHLG----LRQGDCVALL-MGNE--PAYVWLWLGLVKLGCAMACLNYNIRAK
90 100 110 120 130 140
220 230 240 250 260 270
pF1KE0 PLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALDAA
: : ::.::.:.:.:. ..:::::.:. ... .:.:.:: : :. .. .: .
NP_003 SLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSFLDKVDEV
150 160 170 180 190 200
280 290 300 310 320 330
pF1KE0 PSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGATADDVVY
..:.: . :. .:. .:::.::::::::::: :..::.:. . . .:: ::::.:
NP_003 STEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGLTFVSGLKADDVIY
210 220 230 240 250 260
340 350 360 370 380 390
pF1KE0 TVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYLCN
.::.:: .:..:: ::. ::: .: :::.: ::::::...:::: :.:::::::::
NP_003 ITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLCN
270 280 290 300 310 320
400 410 420 430 440 450
pF1KE0 IPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCGAL
::.:.:: : ::::.:::::.:::. : .::: : :.: :..::::.:..::. . ::.
NP_003 SPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVGAV
330 340 350 360 370 380
460 470 480 490 500 510
pF1KE0 GKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYRGP
:... : . . ..:...:.: :::::..:.:. : :: :::. :... :: :: :
NP_003 GRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTPFNGYAGA
390 400 410 420 430 440
520 530 540 550 560 570
pF1KE0 RELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVL
. .:.: .:.: ..::.:.:.::.: .:.:.:.::.::.:::::::::::.: :: ..
NP_003 KAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTV
450 460 470 480 490 500
580 590 600 610 620 630
pF1KE0 SQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFIRI
. :::.:.:::::: :: ::..:::.... .. :::.::.::. .::.:: :.:.::
NP_003 GLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFLRI
510 520 530 540 550 560
640 650 660 670 680 690
pF1KE0 QDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWRL
::..:.:.::: : ::.:::: ... : :. ::. :. . :.: ..:.:. : .:
NP_003 QDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKTLKL
570 580 590 600 610 620
>>NP_054750 (OMIM: 604196) long-chain fatty acid transpo (619 aa)
initn: 1577 init1: 1451 opt: 1637 Z-score: 1807.6 bits: 344.7 E(85289): 6e-94
Smith-Waterman score: 1695; 42.6% identity (72.6% similar) in 625 aa overlap (66-690:9-619)
40 50 60 70 80 90
pF1KE0 LLGDPTCCVLLGLAMLARPWLGPWVPHGLSLAAAALALTLLPARLPPGLRWLPADVIFLA
:.:. ..: .: : : . : : :.
NP_054 MLLSWLTVLGAGMVVLHFLQKLLFPYF-W--DDFWFVL
10 20 30
100 110 120 130 140 150
pF1KE0 KILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELDARACQA
:.. . .... .: : .: : .:. :: . .... : :. ..: :. ..
NP_054 KVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEGD---IYTYQDVDKRSSRV
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE0 AWALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAH
: .. . .:: :. .:::. :. . .:.::::::: .:..: . :. : .
NP_054 AHVFL----NHSSLKKGDTVALLM--SNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLN
100 110 120 130 140
220 230 240 250 260 270
pF1KE0 SVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHP
. . : :.::: :: ..:::::.: .::: . .. . : :: .: :...:..:
NP_054 CIRACGPRALVVGADLLGTVEEILPSL-SENISVWGMKDSVPQ-GVISLKEKLSTSPDEP
150 160 170 180 190 200
280 290 300 310 320 330
pF1KE0 VPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGATADDVVYTVLP
:: . .. .: :.:.::::::::: :.... .::. : .: : :: :.:: .::
NP_054 VPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAVLWAFGCTAHDIVYITLP
210 220 230 240 250 260
340 350 360 370 380 390
pF1KE0 LYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQ
::: . ..:: ::..::::::: :::.: ::.::... :::. :.::: ::::. ..
NP_054 LYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYLCKQSKR
270 280 290 300 310 320
400 410 420 430 440 450
pF1KE0 PEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMS
.. : ::::.:::.:.:::. : .::: :.. :.:..::......::.:: ::.:. .
NP_054 EGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIGAIGRTN
330 340 350 360 370 380
460 470 480 490 500 510
pF1KE0 CLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELS
. ..:: :.:...:.. ::.:..::.:: : ::::::...: ...:: :: :: . .
NP_054 LFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPFFGYAGPYKHT
390 400 410 420 430 440
520 530 540 550 560 570
pF1KE0 ERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVD
. ::. .: ..:::: ::::....:...:::: :: :::::::::::.: :: :....:
NP_054 KDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLD
450 460 470 480 490 500
580 590 600 610 620 630
pF1KE0 FLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAM
:.:..::::: . : ::..:::.. : :. ..: ::.:..: ..::::: :.:.:::. :
NP_054 FIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFLRIQEKM
510 520 530 540 550 560
640 650 660 670 680 690
pF1KE0 EVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWRL
:.:.::::.: .::..::: . .::. .:: .:. :: :.:. . : .:
NP_054 EATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIKL
570 580 590 600 610
>>NP_001017372 (OMIM: 604196) long-chain fatty acid tran (619 aa)
initn: 1577 init1: 1451 opt: 1637 Z-score: 1807.6 bits: 344.7 E(85289): 6e-94
Smith-Waterman score: 1695; 42.6% identity (72.6% similar) in 625 aa overlap (66-690:9-619)
40 50 60 70 80 90
pF1KE0 LLGDPTCCVLLGLAMLARPWLGPWVPHGLSLAAAALALTLLPARLPPGLRWLPADVIFLA
:.:. ..: .: : : . : : :.
NP_001 MLLSWLTVLGAGMVVLHFLQKLLFPYF-W--DDFWFVL
10 20 30
100 110 120 130 140 150
pF1KE0 KILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELDARACQA
:.. . .... .: : .: : .:. :: . .... : :. ..: :. ..
NP_001 KVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEGD---IYTYQDVDKRSSRV
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE0 AWALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAH
: .. . .:: :. .:::. :. . .:.::::::: .:..: . :. : .
NP_001 AHVFL----NHSSLKKGDTVALLM--SNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLN
100 110 120 130 140
220 230 240 250 260 270
pF1KE0 SVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHP
. . : :.::: :: ..:::::.: .::: . .. . : :: .: :...:..:
NP_001 CIRACGPRALVVGADLLGTVEEILPSL-SENISVWGMKDSVPQ-GVISLKEKLSTSPDEP
150 160 170 180 190 200
280 290 300 310 320 330
pF1KE0 VPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGATADDVVYTVLP
:: . .. .: :.:.::::::::: :.... .::. : .: : :: :.:: .::
NP_001 VPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAVLWAFGCTAHDIVYITLP
210 220 230 240 250 260
340 350 360 370 380 390
pF1KE0 LYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQ
::: . ..:: ::..::::::: :::.: ::.::... :::. :.::: ::::. ..
NP_001 LYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYLCKQSKR
270 280 290 300 310 320
400 410 420 430 440 450
pF1KE0 PEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMS
.. : ::::.:::.:.:::. : .::: :.. :.:..::......::.:: ::.:. .
NP_001 EGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIGAIGRTN
330 340 350 360 370 380
460 470 480 490 500 510
pF1KE0 CLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELS
. ..:: :.:...:.. ::.:..::.:: : ::::::...: ...:: :: :: . .
NP_001 LFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPFFGYAGPYKHT
390 400 410 420 430 440
520 530 540 550 560 570
pF1KE0 ERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVD
. ::. .: ..:::: ::::....:...:::: :: :::::::::::.: :: :....:
NP_001 KDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLD
450 460 470 480 490 500
580 590 600 610 620 630
pF1KE0 FLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAM
:.:..::::: . : ::..:::.. : :. ..: ::.:..: ..::::: :.:.:::. :
NP_001 FIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFLRIQEKM
510 520 530 540 550 560
640 650 660 670 680 690
pF1KE0 EVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWRL
:.:.::::.: .::..::: . .::. .:: .:. :: :.:. . : .:
NP_001 EATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIKL
570 580 590 600 610
>>NP_001304913 (OMIM: 604196) long-chain fatty acid tran (619 aa)
initn: 1577 init1: 1451 opt: 1637 Z-score: 1807.6 bits: 344.7 E(85289): 6e-94
Smith-Waterman score: 1695; 42.6% identity (72.6% similar) in 625 aa overlap (66-690:9-619)
40 50 60 70 80 90
pF1KE0 LLGDPTCCVLLGLAMLARPWLGPWVPHGLSLAAAALALTLLPARLPPGLRWLPADVIFLA
:.:. ..: .: : : . : : :.
NP_001 MLLSWLTVLGAGMVVLHFLQKLLFPYF-W--DDFWFVL
10 20 30
100 110 120 130 140 150
pF1KE0 KILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELDARACQA
:.. . .... .: : .: : .:. :: . .... : :. ..: :. ..
NP_001 KVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEGD---IYTYQDVDKRSSRV
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE0 AWALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAH
: .. . .:: :. .:::. :. . .:.::::::: .:..: . :. : .
NP_001 AHVFL----NHSSLKKGDTVALLM--SNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLN
100 110 120 130 140
220 230 240 250 260 270
pF1KE0 SVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHP
. . : :.::: :: ..:::::.: .::: . .. . : :: .: :...:..:
NP_001 CIRACGPRALVVGADLLGTVEEILPSL-SENISVWGMKDSVPQ-GVISLKEKLSTSPDEP
150 160 170 180 190 200
280 290 300 310 320 330
pF1KE0 VPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGATADDVVYTVLP
:: . .. .: :.:.::::::::: :.... .::. : .: : :: :.:: .::
NP_001 VPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAVLWAFGCTAHDIVYITLP
210 220 230 240 250 260
340 350 360 370 380 390
pF1KE0 LYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQ
::: . ..:: ::..::::::: :::.: ::.::... :::. :.::: ::::. ..
NP_001 LYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYLCKQSKR
270 280 290 300 310 320
400 410 420 430 440 450
pF1KE0 PEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMS
.. : ::::.:::.:.:::. : .::: :.. :.:..::......::.:: ::.:. .
NP_001 EGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIGAIGRTN
330 340 350 360 370 380
460 470 480 490 500 510
pF1KE0 CLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELS
. ..:: :.:...:.. ::.:..::.:: : ::::::...: ...:: :: :: . .
NP_001 LFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPFFGYAGPYKHT
390 400 410 420 430 440
520 530 540 550 560 570
pF1KE0 ERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVD
. ::. .: ..:::: ::::....:...:::: :: :::::::::::.: :: :....:
NP_001 KDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLD
450 460 470 480 490 500
580 590 600 610 620 630
pF1KE0 FLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAM
:.:..::::: . : ::..:::.. : :. ..: ::.:..: ..::::: :.:.:::. :
NP_001 FIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFLRIQEKM
510 520 530 540 550 560
640 650 660 670 680 690
pF1KE0 EVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWRL
:.:.::::.: .::..::: . .::. .:: .:. :: :.:. . : .:
NP_001 EATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIKL
570 580 590 600 610
>>NP_077306 (OMIM: 604193) long-chain fatty acid transpo (730 aa)
initn: 1762 init1: 1585 opt: 1629 Z-score: 1797.8 bits: 343.2 E(85289): 2.1e-93
Smith-Waterman score: 1667; 42.9% identity (65.3% similar) in 704 aa overlap (47-690:28-730)
20 30 40 50 60 70
pF1KE0 LWGLGQPVWPVAVALTLRWLLGDPTCCVLLGLAMLARPWLGPWVP--HGLSLAAAALA--
: .:.: : . :: .. :.:: :
NP_077 MGVCQRTRAPWKEKSQLERAALGFRKGGSGMFASGW-NQTVPIEEAGSMAALLLLPL
10 20 30 40 50
80 90 100
pF1KE0 LTLLPA-----RLPPGLRWLPADVIFLAKIL--HLGLKIR--------------GC----
: ::: .: : :::::::. : .. : . .:. : ::
NP_077 LLLLPLLLLKLHLWPQLRWLPADLAFAVRALCCKRALRARALAAAAADPEGPEGGCSLAW
60 70 80 90 100 110
110 120 130 140
pF1KE0 ----LSRQ-PPDTFVDAFERR-----ARAQPGRAL------LVWT-GP-----GAGSVTF
:..: ::. :: :. . .:: : : :: : ::.
NP_077 RLAELAQQRAAHTFLIHGSRRFSYSEAERESNRAARAFLRALGWDWGPDGGDSGEGSAGE
120 130 140 150 160 170
150 160 170 180 190
pF1KE0 GELDAR-ACQAAWALKAEL--GDPASLCAGE-----PTALLVLASQAVPA-LCMWLGLAK
:: : : .:: . ::. :: :. .: : : ..: : : : .:.::::
NP_077 GERAAPGAGDAAAGSGAEFAGGDGAARGGGAAAPLSPGATVALLLPAGPEFLWLWFGLAK
180 190 200 210 220 230
200 210 220 230 240 250
pF1KE0 LGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTS
: ::.. : :: : . : :::.::. :.. :::: :: :.: ... . . .
NP_077 AGLRTAFVPTALRRGPLLHCLRSCGARALVLAPEFLESLEPDLPALRAMGLHLWAAGPGT
240 250 260 270 280 290
260 270 280 290 300 310
pF1KE0 PTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMS
:.. : : ..: . :::. : . . . :.:.::::::::: : ..: ..:: .
NP_077 HPAGISDLLAEVSAEVDGPVPGYLSSPQSITDTCLYIFTSGTTGLPKAARISHLKILQCQ
300 310 320 330 340 350
320 330 340 350 360 370
pF1KE0 KMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGV
. .: :. .::.: .:::::. : ..::.::. .::: :: :::.. ::.::.:: :
NP_077 GFYQLCGVHQEDVIYLALPLYHMSGSLLGIVGCMGIGATVVLKSKFSAGQFWEDCQQHRV
360 370 380 390 400 410
380 390 400 410 420 430
pF1KE0 TVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTE
::. :.::: ::: : : . .: : ::::.:.::: :.:: : .::::... :.:: ::
NP_077 TVFQYIGELCRYLVNQPPSKAERGHKVRLAVGSGLRPDTWERFVRRFGPLQVLETYGLTE
420 430 440 450 460 470
440 450 460 470 480 490
pF1KE0 GNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLL
::.. .::.:. ::.:. : : . . :: :...:. ..::.:: :: :. .. ::::::.
NP_077 GNVATINYTGQRGAVGRASWLYKHIFPFSLIRYDVTTGEPIRDPQGHCMATSPGEPGLLV
480 490 500 510 520 530
500 510 520 530 540 550
pF1KE0 TKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFR
. : .:.::.:: : ::.. ::...: . :::..::::.:. : .::: :.:: :::::
NP_077 APVSQQSPFLGYAGGPELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDRTGDTFR
540 550 560 570 580 590
560 570 580 590 600 610
pF1KE0 WKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHV
::::::.: :: :. .::::.:::::: ::: ::..::::. : : ...: .:: ::
NP_077 WKGENVATTEVAEVFEALDFLQEVNVYGVTVPGHEGRAGMAALVLRPPHALDLMQLYTHV
600 610 620 630 640 650
620 630 640 650 660 670
pF1KE0 RAWLPAYATPHFIRIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLT
:: :: :.:.:.:... .: ::: .:.:.. :::. . . :::.:::. . .. :::
NP_077 SENLPPYARPRFLRLQESLATTETFKQQKVRMANEGFDPSTLSDPLYVLDQAVGAYLPLT
660 670 680 690 700 710
680 690
pF1KE0 AEMYQAVCEGTWRL
. :.:. :. :.
NP_077 TARYSALLAGNLRI
720 730
>>NP_001304858 (OMIM: 604193) long-chain fatty acid tran (695 aa)
initn: 1616 init1: 1439 opt: 1483 Z-score: 1636.9 bits: 313.3 E(85289): 1.9e-84
Smith-Waterman score: 1521; 43.3% identity (64.6% similar) in 646 aa overlap (47-632:28-672)
20 30 40 50 60 70
pF1KE0 LWGLGQPVWPVAVALTLRWLLGDPTCCVLLGLAMLARPWLGPWVP--HGLSLAAAALA--
: .:.: : . :: .. :.:: :
NP_001 MGVCQRTRAPWKEKSQLERAALGFRKGGSGMFASGW-NQTVPIEEAGSMAALLLLPL
10 20 30 40 50
80 90 100
pF1KE0 LTLLPA-----RLPPGLRWLPADVIFLAKIL--HLGLKIR--------------GC----
: ::: .: : :::::::. : .. : . .:. : ::
NP_001 LLLLPLLLLKLHLWPQLRWLPADLAFAVRALCCKRALRARALAAAAADPEGPEGGCSLAW
60 70 80 90 100 110
110 120 130 140
pF1KE0 ----LSRQ-PPDTFVDAFERR-----ARAQPGRAL------LVWT-GP-----GAGSVTF
:..: ::. :: :. . .:: : : :: : ::.
NP_001 RLAELAQQRAAHTFLIHGSRRFSYSEAERESNRAARAFLRALGWDWGPDGGDSGEGSAGE
120 130 140 150 160 170
150 160 170 180 190
pF1KE0 GELDAR-ACQAAWALKAEL--GDPASLCAGE-----PTALLVLASQAVPA-LCMWLGLAK
:: : : .:: . ::. :: :. .: : : ..: : : : .:.::::
NP_001 GERAAPGAGDAAAGSGAEFAGGDGAARGGGAAAPLSPGATVALLLPAGPEFLWLWFGLAK
180 190 200 210 220 230
200 210 220 230 240 250
pF1KE0 LGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTS
: ::.. : :: : . : :::.::. :.. :::: :: :.: ... . . .
NP_001 AGLRTAFVPTALRRGPLLHCLRSCGARALVLAPEFLESLEPDLPALRAMGLHLWAAGPGT
240 250 260 270 280 290
260 270 280 290 300 310
pF1KE0 PTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMS
:.. : : ..: . :::. : . . . :.:.::::::::: : ..: ..:: .
NP_001 HPAGISDLLAEVSAEVDGPVPGYLSSPQSITDTCLYIFTSGTTGLPKAARISHLKILQCQ
300 310 320 330 340 350
320 330 340 350 360 370
pF1KE0 KMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGV
. .: :. .::.: .:::::. : ..::.::. .::: :: :::.. ::.::.:: :
NP_001 GFYQLCGVHQEDVIYLALPLYHMSGSLLGIVGCMGIGATVVLKSKFSAGQFWEDCQQHRV
360 370 380 390 400 410
380 390 400 410 420 430
pF1KE0 TVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTE
::. :.::: ::: : : . .: : ::::.:.::: :.:: : .::::... :.:: ::
NP_001 TVFQYIGELCRYLVNQPPSKAERGHKVRLAVGSGLRPDTWERFVRRFGPLQVLETYGLTE
420 430 440 450 460 470
440 450 460 470 480 490
pF1KE0 GNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLL
::.. .::.:. ::.:. : : . . :: :...:. ..::.:: :: :. .. ::::::.
NP_001 GNVATINYTGQRGAVGRASWLYKHIFPFSLIRYDVTTGEPIRDPQGHCMATSPGEPGLLV
480 490 500 510 520 530
500 510 520 530 540 550
pF1KE0 TKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFR
. : .:.::.:: : ::.. ::...: . :::..::::.:. : .::: :.:: :::::
NP_001 APVSQQSPFLGYAGGPELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDRTGDTFR
540 550 560 570 580 590
560 570 580 590 600 610
pF1KE0 WKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHV
::::::.: :: :. .::::.:::::: ::: ::..::::. : : ...: .:: ::
NP_001 WKGENVATTEVAEVFEALDFLQEVNVYGVTVPGHEGRAGMAALVLRPPHALDLMQLYTHV
600 610 620 630 640 650
620 630 640 650 660 670
pF1KE0 RAWLPAYATPHFIRIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLT
:: :: :.:.:.:
NP_001 SENLPPYARPRFLRLQAVGAYLPLTTARYSALLAGNLRI
660 670 680 690
690 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:56:07 2016 done: Thu Nov 3 13:56:09 2016
Total Scan time: 11.300 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]