FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0369, 553 aa 1>>>pF1KE0369 553 - 553 aa - 553 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.5813+/-0.000667; mu= -12.8756+/- 0.039 mean_var=698.6767+/-155.434, 0's: 0 Z-trim(114.9): 1432 B-trim: 0 in 0/52 Lambda= 0.048522 statistics sampled from 23165 (25066) to 23165 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.655), E-opt: 0.2 (0.294), width: 16 Scan time: 7.440 The best scores are: opt bits E(85289) XP_016861206 (OMIM: 606987) PREDICTED: rhodopsin k ( 553) 3703 275.8 2.4e-73 NP_631948 (OMIM: 606987) rhodopsin kinase [Homo sa ( 553) 3703 275.8 2.4e-73 NP_892027 (OMIM: 137026) G protein-coupled recepto ( 578) 1688 134.8 7.2e-31 NP_001004105 (OMIM: 600869) G protein-coupled rece ( 560) 1652 132.3 4.1e-30 NP_001004106 (OMIM: 600869) G protein-coupled rece ( 576) 1652 132.3 4.1e-30 NP_002073 (OMIM: 600869) G protein-coupled recepto ( 589) 1652 132.3 4.2e-30 NP_002920 (OMIM: 180381,613411) rhodopsin kinase [ ( 563) 1649 132.0 4.7e-30 NP_001004057 (OMIM: 137026) G protein-coupled rece ( 532) 1647 131.9 5e-30 NP_005299 (OMIM: 600870) G protein-coupled recepto ( 590) 1627 130.5 1.4e-29 NP_001004056 (OMIM: 137026) G protein-coupled rece ( 546) 1609 129.2 3.2e-29 XP_006714922 (OMIM: 600869) PREDICTED: G protein-c ( 557) 1601 128.7 4.8e-29 NP_005298 (OMIM: 137026) G protein-coupled recepto ( 500) 1568 126.3 2.2e-28 XP_006714921 (OMIM: 600869) PREDICTED: G protein-c ( 559) 1559 125.7 3.7e-28 XP_005269765 (OMIM: 600870) PREDICTED: G protein-c ( 558) 1551 125.2 5.5e-28 XP_011532839 (OMIM: 600869) PREDICTED: G protein-c ( 550) 1426 116.4 2.3e-25 XP_016863545 (OMIM: 137026) PREDICTED: G protein-c ( 440) 1329 109.5 2.3e-23 XP_016863543 (OMIM: 137026) PREDICTED: G protein-c ( 486) 1329 109.6 2.4e-23 XP_016863548 (OMIM: 137026) PREDICTED: G protein-c ( 384) 1261 104.6 5.7e-22 XP_016863546 (OMIM: 137026) PREDICTED: G protein-c ( 384) 1261 104.6 5.7e-22 XP_016863549 (OMIM: 137026) PREDICTED: G protein-c ( 384) 1261 104.6 5.7e-22 XP_016863547 (OMIM: 137026) PREDICTED: G protein-c ( 384) 1261 104.6 5.7e-22 XP_011511751 (OMIM: 137026) PREDICTED: G protein-c ( 585) 1261 104.9 7.2e-22 XP_016863544 (OMIM: 137026) PREDICTED: G protein-c ( 454) 1250 104.0 1.1e-21 XP_016863541 (OMIM: 137026) PREDICTED: G protein-c ( 591) 1252 104.3 1.1e-21 XP_011511750 (OMIM: 137026) PREDICTED: G protein-c ( 611) 1252 104.3 1.1e-21 XP_011511749 (OMIM: 137026) PREDICTED: G protein-c ( 617) 1252 104.3 1.2e-21 XP_016863552 (OMIM: 137026) PREDICTED: G protein-c ( 338) 1220 101.7 3.9e-21 XP_011511752 (OMIM: 137026) PREDICTED: G protein-c ( 571) 1211 101.4 8.1e-21 XP_016863550 (OMIM: 137026) PREDICTED: G protein-c ( 367) 1197 100.1 1.2e-20 XP_006713943 (OMIM: 137026) PREDICTED: G protein-c ( 367) 1197 100.1 1.2e-20 XP_005248019 (OMIM: 137026) PREDICTED: G protein-c ( 367) 1197 100.1 1.2e-20 XP_016863551 (OMIM: 137026) PREDICTED: G protein-c ( 367) 1197 100.1 1.2e-20 XP_016876173 (OMIM: 180381,613411) PREDICTED: rhod ( 328) 1095 92.9 1.6e-18 XP_011511755 (OMIM: 137026) PREDICTED: G protein-c ( 525) 1054 90.4 1.6e-17 NP_005151 (OMIM: 109636) beta-adrenergic receptor ( 688) 963 84.2 1.5e-15 XP_005269764 (OMIM: 600870) PREDICTED: G protein-c ( 560) 936 82.1 5e-15 NP_001610 (OMIM: 109635) beta-adrenergic receptor ( 689) 930 81.8 7.5e-15 XP_011532840 (OMIM: 600869) PREDICTED: G protein-c ( 324) 919 80.6 8.4e-15 XP_016863555 (OMIM: 137026) PREDICTED: G protein-c ( 292) 902 79.3 1.8e-14 XP_016863553 (OMIM: 137026) PREDICTED: G protein-c ( 338) 902 79.4 2e-14 XP_011543075 (OMIM: 109635) PREDICTED: beta-adrene ( 659) 899 79.6 3.3e-14 XP_011511757 (OMIM: 137026) PREDICTED: G protein-c ( 479) 893 79.0 3.7e-14 XP_011511756 (OMIM: 137026) PREDICTED: G protein-c ( 525) 893 79.1 3.9e-14 XP_011511754 (OMIM: 137026) PREDICTED: G protein-c ( 565) 893 79.1 4e-14 XP_011511753 (OMIM: 137026) PREDICTED: G protein-c ( 571) 893 79.1 4.1e-14 XP_011528277 (OMIM: 109636) PREDICTED: beta-adrene ( 523) 873 77.7 1e-13 XP_016876947 (OMIM: 601367,605437) PREDICTED: prot ( 522) 655 62.4 4e-09 XP_011535257 (OMIM: 601367,605437) PREDICTED: prot ( 603) 655 62.5 4.3e-09 XP_011535256 (OMIM: 601367,605437) PREDICTED: prot ( 604) 655 62.5 4.3e-09 NP_006246 (OMIM: 601367,605437) protein kinase C e ( 683) 655 62.6 4.6e-09 >>XP_016861206 (OMIM: 606987) PREDICTED: rhodopsin kinas (553 aa) initn: 3703 init1: 3703 opt: 3703 Z-score: 1437.7 bits: 275.8 E(85289): 2.4e-73 Smith-Waterman score: 3703; 100.0% identity (100.0% similar) in 553 aa overlap (1-553:1-553) 10 20 30 40 50 60 pF1KE0 MVDMGALDNLIANTAYLQARKPSDCDSKELQRRRRSLALPGLQGCAELRQKLSLNFHSLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVDMGALDNLIANTAYLQARKPSDCDSKELQRRRRSLALPGLQGCAELRQKLSLNFHSLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EQQPIGRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQQPIGRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 NPQPFLSQAVATKCQAATTEEERVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQWKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPQPFLSQAVATKCQAATTEEERVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQWKL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 FEMQPVSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEMQPVSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 EILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 ACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 ILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 EEAKDICRLFLAKKPEQRLGSREKSDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSVVYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEAKDICRLFLAKKPEQRLGSREKSDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSVVYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 KDIAEIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELNDPNRPTGCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDIAEIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELNDPNRPTGCE 490 500 510 520 530 540 550 pF1KE0 EGNSSKSGVCLLL ::::::::::::: XP_016 EGNSSKSGVCLLL 550 >>NP_631948 (OMIM: 606987) rhodopsin kinase [Homo sapien (553 aa) initn: 3703 init1: 3703 opt: 3703 Z-score: 1437.7 bits: 275.8 E(85289): 2.4e-73 Smith-Waterman score: 3703; 100.0% identity (100.0% similar) in 553 aa overlap (1-553:1-553) 10 20 30 40 50 60 pF1KE0 MVDMGALDNLIANTAYLQARKPSDCDSKELQRRRRSLALPGLQGCAELRQKLSLNFHSLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 MVDMGALDNLIANTAYLQARKPSDCDSKELQRRRRSLALPGLQGCAELRQKLSLNFHSLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EQQPIGRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 EQQPIGRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 NPQPFLSQAVATKCQAATTEEERVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQWKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 NPQPFLSQAVATKCQAATTEEERVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQWKL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 FEMQPVSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 FEMQPVSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 EILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 EILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 ACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 ACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 ILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 ILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 EEAKDICRLFLAKKPEQRLGSREKSDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSVVYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 EEAKDICRLFLAKKPEQRLGSREKSDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSVVYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 KDIAEIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELNDPNRPTGCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 KDIAEIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELNDPNRPTGCE 490 500 510 520 530 540 550 pF1KE0 EGNSSKSGVCLLL ::::::::::::: NP_631 EGNSSKSGVCLLL 550 >>NP_892027 (OMIM: 137026) G protein-coupled receptor ki (578 aa) initn: 1581 init1: 869 opt: 1688 Z-score: 675.2 bits: 134.8 E(85289): 7.2e-31 Smith-Waterman score: 1688; 47.9% identity (75.4% similar) in 528 aa overlap (7-531:3-526) 10 20 30 40 50 pF1KE0 MVDMGALDNLIANTAYLQARKPS-DCDSKELQRRRRSLALPGLQGCAELRQKLSLNFHSL :.:..::. :.::. . : . .. .. :.:: .. :.:::... .. :: NP_892 MELENIVANSLLLKARQGGYGKKSGRSKKWKEILTLPPVSQCSELRHSIEKDYSSL 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 CEQQPIGRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAP :..:::::::::.: : ::... ::. : ..:.:.. .: .:. : . : NP_892 CDKQPIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLA- 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 GNPQPFLSQAVATKCQAATTEEE-RVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQW : : . :.:.:. . ::. : : .:. .::... :.....:::: NP_892 -APLPEIPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQW 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 KLFEMQPVSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALL : .: :::. . : ..::::::::::::: ::. ::::::::::.:::.::. :: ::: NP_892 KWLERQPVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALN 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 EKEILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSA ::.:::::.: :.::::::.:.: ::::...::::::::::::.:. :.: .:..::.: NP_892 EKRILEKVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 QIACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMA .. ::. :.. :::::.::::.:::: :. :.::::::.:. :. . :.:: :::: NP_892 ELCCGLEDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMA 300 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 PEILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDN ::.. .. .:.. ::...:: ::::. :..::: :::::. :.. :: .: ... .. NP_892 PEVVNNE-KYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYS-EK 360 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 FTEEAKDICRLFLAKKPEQRLGSR-EKSDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSV :.:.::.:::..:.:.: .::: : : . ..: :: ::: ::::...:::: ::: . NP_892 FSEDAKSICRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHA 420 430 440 450 460 470 480 490 500 510 520 530 pF1KE0 VYAKDIAEIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELNDPNRPT :: ::. .:..:: :.:. .: :..:. :::: : : ::.:.::.: :...: NP_892 VYCKDVLDIEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNEMIESGCFKDINKSESEE 480 490 500 510 520 530 540 550 pF1KE0 GCEEGNSSKSGVCLLL NP_892 ALPLDLDKNIHTPVSRPNRGFFYRLFRRGGCLTMVPSEKEVEPKQC 540 550 560 570 >>NP_001004105 (OMIM: 600869) G protein-coupled receptor (560 aa) initn: 1526 init1: 887 opt: 1652 Z-score: 661.7 bits: 132.3 E(85289): 4.1e-30 Smith-Waterman score: 1652; 46.5% identity (73.8% similar) in 527 aa overlap (7-531:3-525) 10 20 30 40 50 pF1KE0 MVDMGALDNLIANTAYLQARKPSDCDSKELQRR-RRSLALPGLQGCAELRQKLSLNFHSL :.:..:::. :.::. . . : ... :. : .: .. : ::: .: ..::: NP_001 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSL 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 CEQQPIGRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAP ::.::::: :::.: :: : . . ..::. : ..:.. . : . : :. . : .: NP_001 CERQPIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQ-LTQNFLSHTGP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 GNPQPFLSQAVATKCQAATTEEERVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQWK . : . . ..:.: . . .:. :: :.. : ....::::: NP_001 -DLIPEVPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 LFEMQPVSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLE .: :::. . : ..::::::::::::: ::. ::::::::::.:::.::. :: ::: : NP_001 WLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 KEILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQ :.:::::.: :.::::::.:.: ::::..::::::::::::..: :. .:..::.:. NP_001 KQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 IACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAP : ::. ::. :::::.::::.:::: :. :.:::::::.. :. : :.:: ::::: NP_001 ICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAP 300 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 EILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNF :.. .. :.. ::.:.:: .:::.::..::.. :.:...:.. .: ... . . : NP_001 EVVKNE-RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEV-ERLVKEVPEEYSERF 360 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 TEEAKDICRLFLAKKPEQRLGSREKSD-DPRKHHFFKTINFPRLEAGLIEPPFVPDPSVV . .:...: .: : : .::: : : . ..: .:: .:: :: ::..:::: :::... NP_001 SPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAI 420 430 440 450 460 470 480 490 500 510 520 530 pF1KE0 YAKDIAEIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELNDPNRPTG : ::. .:..:: :.:::.. :..:...::::.::: ::.:..:: :.::: NP_001 YCKDVLDIEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGS 480 490 500 510 520 530 540 550 pF1KE0 CEEGNSSKSGVCLLL NP_001 VPPDLDWKGQPPAPPKKGLLQRLFSRQR 540 550 560 >>NP_001004106 (OMIM: 600869) G protein-coupled receptor (576 aa) initn: 1526 init1: 887 opt: 1652 Z-score: 661.6 bits: 132.3 E(85289): 4.1e-30 Smith-Waterman score: 1652; 46.5% identity (73.8% similar) in 527 aa overlap (7-531:3-525) 10 20 30 40 50 pF1KE0 MVDMGALDNLIANTAYLQARKPSDCDSKELQRR-RRSLALPGLQGCAELRQKLSLNFHSL :.:..:::. :.::. . . : ... :. : .: .. : ::: .: ..::: NP_001 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSL 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 CEQQPIGRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAP ::.::::: :::.: :: : . . ..::. : ..:.. . : . : :. . : .: NP_001 CERQPIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQ-LTQNFLSHTGP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 GNPQPFLSQAVATKCQAATTEEERVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQWK . : . . ..:.: . . .:. :: :.. : ....::::: NP_001 -DLIPEVPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 LFEMQPVSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLE .: :::. . : ..::::::::::::: ::. ::::::::::.:::.::. :: ::: : NP_001 WLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 KEILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQ :.:::::.: :.::::::.:.: ::::..::::::::::::..: :. .:..::.:. NP_001 KQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 IACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAP : ::. ::. :::::.::::.:::: :. :.:::::::.. :. : :.:: ::::: NP_001 ICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAP 300 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 EILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNF :.. .. :.. ::.:.:: .:::.::..::.. :.:...:.. .: ... . . : NP_001 EVVKNE-RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEV-ERLVKEVPEEYSERF 360 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 TEEAKDICRLFLAKKPEQRLGSREKSD-DPRKHHFFKTINFPRLEAGLIEPPFVPDPSVV . .:...: .: : : .::: : : . ..: .:: .:: :: ::..:::: :::... NP_001 SPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAI 420 430 440 450 460 470 480 490 500 510 520 530 pF1KE0 YAKDIAEIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELNDPNRPTG : ::. .:..:: :.:::.. :..:...::::.::: ::.:..:: :.::: NP_001 YCKDVLDIEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGS 480 490 500 510 520 530 540 550 pF1KE0 CEEGNSSKSGVCLLL NP_001 VPPDLDWKGQPPAPPKKGLLQRLFSRQDCCGNCSDSEEELPTRL 540 550 560 570 >>NP_002073 (OMIM: 600869) G protein-coupled receptor ki (589 aa) initn: 1526 init1: 887 opt: 1652 Z-score: 661.5 bits: 132.3 E(85289): 4.2e-30 Smith-Waterman score: 1652; 46.5% identity (73.8% similar) in 527 aa overlap (7-531:3-525) 10 20 30 40 50 pF1KE0 MVDMGALDNLIANTAYLQARKPSDCDSKELQRR-RRSLALPGLQGCAELRQKLSLNFHSL :.:..:::. :.::. . . : ... :. : .: .. : ::: .: ..::: NP_002 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSL 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 CEQQPIGRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAP ::.::::: :::.: :: : . . ..::. : ..:.. . : . : :. . : .: NP_002 CERQPIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQ-LTQNFLSHTGP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 GNPQPFLSQAVATKCQAATTEEERVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQWK . : . . ..:.: . . .:. :: :.. : ....::::: NP_002 -DLIPEVPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 LFEMQPVSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLE .: :::. . : ..::::::::::::: ::. ::::::::::.:::.::. :: ::: : NP_002 WLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 KEILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQ :.:::::.: :.::::::.:.: ::::..::::::::::::..: :. .:..::.:. NP_002 KQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 IACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAP : ::. ::. :::::.::::.:::: :. :.:::::::.. :. : :.:: ::::: NP_002 ICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAP 300 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 EILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNF :.. .. :.. ::.:.:: .:::.::..::.. :.:...:.. .: ... . . : NP_002 EVVKNE-RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEV-ERLVKEVPEEYSERF 360 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 TEEAKDICRLFLAKKPEQRLGSREKSD-DPRKHHFFKTINFPRLEAGLIEPPFVPDPSVV . .:...: .: : : .::: : : . ..: .:: .:: :: ::..:::: :::... NP_002 SPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAI 420 430 440 450 460 470 480 490 500 510 520 530 pF1KE0 YAKDIAEIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELNDPNRPTG : ::. .:..:: :.:::.. :..:...::::.::: ::.:..:: :.::: NP_002 YCKDVLDIEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGS 480 490 500 510 520 530 540 550 pF1KE0 CEEGNSSKSGVCLLL NP_002 VPPDLDWKGQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR 540 550 560 570 580 >>NP_002920 (OMIM: 180381,613411) rhodopsin kinase [Homo (563 aa) initn: 1425 init1: 716 opt: 1649 Z-score: 660.5 bits: 132.0 E(85289): 4.7e-30 Smith-Waterman score: 1669; 46.9% identity (73.5% similar) in 567 aa overlap (2-552:1-562) 10 20 30 40 50 pF1KE0 MVDMGALDNLIANTAYLQARKPSDCDSKELQRRRRSLA---LPGLQGCAELRQKLSLNFH .:.:.:....::.:.. :: : .:.. .: .. :: :: :. : ::..:::.:. NP_002 MDFGSLETVVANSAFIAARGSFDGSSSQPSRDKKYLAKLKLPPLSKCESLRDSLSLEFE 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 SLCEQQPIGRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAP :.: .::::..::..:: .. : . .:..... :.. ..: : ..: . : NP_002 SVCLEQPIGKKLFQQFLQSAEKHLPALELWKDIEDYDTADNDLQPQKA-QTILAQYLD-P 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 APGNPQPFLSQAVATKCQAATTEEERVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQ ::......: . . .: . : .: ..: : . ::.... : .. .::: NP_002 QAKLFCSFLDEGIVAKFKEGPVEIQDGLFQPLLQA-TLAHLGQAPFQEYLGSLYFLRFLQ 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 WKLFEMQPVSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMAL :: .: ::... .: .:::::::::::: : :.: :::.::::::.::::::. : . :. NP_002 WKWLEAQPMGEDWFLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYQGAM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 LEKEILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTR--GLDMSRVIF .::.:: :: : ::::::::::.:. :::::..:::::...:::::. . :. :..: NP_002 VEKKILMKVHSRFIVSLAYAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALF 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 YSAQIACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQ-RAGTN :.::: ::. :::. :::::.::::::::. :: :.::::::::. :. :. ::: NP_002 YTAQIICGLEHLHQRRIVYRDLKPENVLLDNDGNVRISDLGLAVELLDGQSKTKGYAGTP 300 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 GYMAPEILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKF :.:::: :.. :.. ::.::.: ..:::.:.: ::. ::: ...::.: ... ::. NP_002 GFMAPE-LLQGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKHRIISEPVKY 360 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 QHDNFTEEAKDICRLFLAKKPEQRLGSREKSDDP-RKHHFFKTINFPRLEAGLIEPPFVP :.:.. .::.:. .: : ::.::: :... : : : .:: .:. .::::.. :::.: NP_002 P-DKFSQASKDFCEALLEKDPEKRLGFRDETCDKLRAHPLFKDLNWRQLEAGMLMPPFIP 420 430 440 450 460 470 480 490 500 510 520 530 pF1KE0 DPSVVYAKDIAEIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELN-- : ..:::::: .. :: :.:: :: : .::..:::: :: ::::.::::.: ::: NP_002 DSKTVYAKDIQDVGAFSTVKGVAFDKTDTEFFQEFATGNCPIPWQEEMIETGIFGELNVW 480 490 500 510 520 530 540 550 pF1KE0 --D---PNRPTGCEEGNSS--KSGVCLLL : :. : :.:: :::.::. NP_002 RSDGQMPDDMKGISGGSSSSSKSGMCLVS 540 550 560 >>NP_001004057 (OMIM: 137026) G protein-coupled receptor (532 aa) initn: 1540 init1: 869 opt: 1647 Z-score: 660.0 bits: 131.9 E(85289): 5e-30 Smith-Waterman score: 1647; 48.0% identity (75.0% similar) in 517 aa overlap (7-520:3-515) 10 20 30 40 50 pF1KE0 MVDMGALDNLIANTAYLQARKPS-DCDSKELQRRRRSLALPGLQGCAELRQKLSLNFHSL :.:..::. :.::. . : . .. .. :.:: .. :.:::... .. :: NP_001 MELENIVANSLLLKARQGGYGKKSGRSKKWKEILTLPPVSQCSELRHSIEKDYSSL 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 CEQQPIGRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAP :..:::::::::.: : ::... ::. : ..:.:.. .: .:. : . : NP_001 CDKQPIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLA- 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 GNPQPFLSQAVATKCQAATTEEE-RVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQW : : . :.:.:. . ::. : : .:. .::... :.....:::: NP_001 -APLPEIPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQW 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 KLFEMQPVSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALL : .: :::. . : ..::::::::::::: ::. ::::::::::.:::.::. :: ::: NP_001 KWLERQPVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALN 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 EKEILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSA ::.:::::.: :.::::::.:.: ::::...::::::::::::.:. :.: .:..::.: NP_001 EKRILEKVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 QIACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMA .. ::. :.. :::::.::::.:::: :. :.::::::.:. :. . :.:: :::: NP_001 ELCCGLEDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMA 300 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 PEILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDN ::.. .. .:.. ::...:: ::::. :..::: :::::. :.. :: .: ... .. NP_001 PEVVNNE-KYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYS-EK 360 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 FTEEAKDICRLFLAKKPEQRLGSR-EKSDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSV :.:.::.:::..:.:.: .::: : : . ..: :: ::: ::::...:::: ::: . NP_001 FSEDAKSICRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHA 420 430 440 450 460 470 480 490 500 510 520 530 pF1KE0 VYAKDIAEIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELNDPNRPT :: ::. .:..:: :.:. .: :..:. :::: : : ::.: NP_001 VYCKDVLDIEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNEGCLTMVPSEKEVEPKQC 480 490 500 510 520 530 540 550 pF1KE0 GCEEGNSSKSGVCLLL >>NP_005299 (OMIM: 600870) G protein-coupled receptor ki (590 aa) initn: 1099 init1: 902 opt: 1627 Z-score: 652.0 bits: 130.5 E(85289): 1.4e-29 Smith-Waterman score: 1627; 45.8% identity (74.5% similar) in 533 aa overlap (7-534:3-530) 10 20 30 40 50 pF1KE0 MVDMGALDNLIANTAYLQARKPSDCDSKELQRR-RRSLALPGLQGCAELRQKLSLNFHSL :.:..:::. :.::. . : ... .. : .: .. : .::. .. .. :: NP_005 MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSL 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 CEQQPIGRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGL-VATCASAPA :..::::: :::.: : : .. ::..: ..:.. : . . .: . : .: NP_005 CDKQPIGRLLFRQFCETRPGLECYIQFLDSVAEYEVT---PDEKLGEKGKEIMTKYLTPK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 PGNPQPFLSQAVATKCQAATTEEERVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQW ..: .... . .. . . .:. .::.... : :.:.:::: NP_005 SPVFIAQVGQDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQW 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 KLFEMQPVSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALL : .: :::. . : ..::::::::::::: ::. ::::::::.:.:::.::. ::.::: NP_005 KWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALN 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 EKEILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSA ::.:::::.: :.:.::::.:.: ::::...::::::::::::.:. :.. :..::.: NP_005 EKQILEKVNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 QIACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMA .: ::. ::. . ::::.::::.:::: :. :.:::::::.. : : :.:: :::: NP_005 EILCGLEDLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMA 300 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 PEILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDN ::.: .. :. :....:: ::::. :..::. ::::..:.. .:.:. : ..: . NP_005 PEVLNNQ-RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSH-K 360 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 FTEEAKDICRLFLAKKPEQRLGSREK-SDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSV :.::::.::...:.: .:::: .:. . . ..: ::...:: :::::...::::::: . NP_005 FSEEAKSICKMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRA 420 430 440 450 460 470 480 490 500 510 520 530 pF1KE0 VYAKDIAEIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELN--DPNR :: ::. .:..:: :.::..: : .:...:.::.: : ::.:.::: :.::: :: NP_005 VYCKDVLDIEQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNG 480 490 500 510 520 530 540 550 pF1KE0 PTGCEEGNSSKSGVCLLL NP_005 TLPPDLNRNHPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS 540 550 560 570 580 590 >>NP_001004056 (OMIM: 137026) G protein-coupled receptor (546 aa) initn: 1531 init1: 869 opt: 1609 Z-score: 645.5 bits: 129.2 E(85289): 3.2e-29 Smith-Waterman score: 1609; 49.2% identity (75.5% similar) in 486 aa overlap (48-531:13-494) 20 30 40 50 60 70 pF1KE0 QARKPSDCDSKELQRRRRSLALPGLQGCAELRQKLSLNFHSLCEQQPIGRRLFRDFLATV :. . .. :::..:::::::::.: : NP_001 MELENIVANSLLLKARQEKDYSSLCDKQPIGRRLFRQFCDTK 10 20 30 40 80 90 100 110 120 130 pF1KE0 PTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAPGNPQPFLSQAVATKCQAA ::... ::. : ..:.:.. .: .:. : . : : : . :.:.:. . NP_001 PTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLA--APLPEIPPDVVTECRLG 50 60 70 80 90 100 140 150 160 170 180 190 pF1KE0 TTEEE-RVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQWKLFEMQPVSDKYFTEFRV ::. : : .:. .::... :.....::::: .: :::. . : ..:: NP_001 LKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQPVTKNTFRHYRV 110 120 130 140 150 160 200 210 220 230 240 250 pF1KE0 LGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEKEILEKVSSPFIVSLAY ::::::::::: ::. ::::::::::.:::.::. :: ::: ::.:::::.: :.::::: NP_001 LGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILEKVQSRFVVSLAY 170 180 190 200 210 220 260 270 280 290 300 310 pF1KE0 AFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQIACGMLHLHELGIVYRD :.:.: ::::...::::::::::::.:. :.: .:..::.:.. ::. :.. ::::: NP_001 AYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQRERIVYRD 230 240 250 260 270 280 320 330 340 350 360 370 pF1KE0 MKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAPEILMEKVSYSYPVDWFA .::::.:::: :. :.::::::.:. :. . :.:: ::::::.. .. .:.. ::.. NP_001 LKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNNE-KYTFSPDWWG 290 300 310 320 330 380 390 400 410 420 430 pF1KE0 MGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFTEEAKDICRLFLAKKPE .:: ::::. :..::: :::::. :.. :: .: ... ..:.:.::.:::..:.:.: NP_001 LGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYS-EKFSEDAKSICRMLLTKNPS 340 350 360 370 380 390 440 450 460 470 480 490 pF1KE0 QRLGSR-EKSDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSVVYAKDIAEIDDFSEVRGV .::: : : . ..: :: ::: ::::...:::: ::: .:: ::. .:..:: :.:. NP_001 KRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLDIEQFSVVKGI 400 410 420 430 440 450 500 510 520 530 540 550 pF1KE0 EFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELNDPNRPTGCEEGNSSKSGVCLLL .: :..:. :::: : : ::.:.::.: :...: NP_001 YLDTADEDFYARFATGCVSIPWQNEMIESGCFKDINKSESEEALPLDLDKNIHTPVSRPN 460 470 480 490 500 510 NP_001 RGFFYRLFRRGGCLTMVPSEKEVEPKQC 520 530 540 553 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:02:15 2016 done: Sat Nov 5 12:02:16 2016 Total Scan time: 7.440 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]