FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0385, 765 aa 1>>>pF1KE0385 765 - 765 aa - 765 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8419+/-0.000971; mu= 17.6842+/- 0.058 mean_var=76.2661+/-15.640, 0's: 0 Z-trim(105.2): 42 B-trim: 0 in 0/49 Lambda= 0.146862 statistics sampled from 8253 (8285) to 8253 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.597), E-opt: 0.2 (0.255), width: 16 Scan time: 3.940 The best scores are: opt bits E(32554) CCDS3996.1 SLC30A5 gene_id:64924|Hs108|chr5 ( 765) 5065 1083.2 0 CCDS776.1 SLC30A7 gene_id:148867|Hs108|chr1 ( 376) 642 145.9 1.1e-34 CCDS34173.1 SLC30A5 gene_id:64924|Hs108|chr5 ( 118) 602 137.2 1.5e-32 CCDS31026.1 SLC30A10 gene_id:55532|Hs108|chr1 ( 485) 280 69.2 1.7e-11 >>CCDS3996.1 SLC30A5 gene_id:64924|Hs108|chr5 (765 aa) initn: 5065 init1: 5065 opt: 5065 Z-score: 5795.8 bits: 1083.2 E(32554): 0 Smith-Waterman score: 5065; 100.0% identity (100.0% similar) in 765 aa overlap (1-765:1-765) 10 20 30 40 50 60 pF1KE0 MEEKYGGDVLAGPGGGGGLGPVDVPSARLTKYIVLLCFTKFLKAVGLFESYDLLKAVHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS39 MEEKYGGDVLAGPGGGGGLGPVDVPSARLTKYIVLLCFTKFLKAVGLFESYDLLKAVHIV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 QFIFILKLGTAFFMVLFQKPFSSGKTITKHQWIKIFKHAVAGCIISLLWFFGLTLCGPLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS39 QFIFILKLGTAFFMVLFQKPFSSGKTITKHQWIKIFKHAVAGCIISLLWFFGLTLCGPLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TLLLFEHSDIVVISLLSVLFTSSGGGPAKTRGAAFFIIAVICLLLFDNDDLMAKMAEHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS39 TLLLFEHSDIVVISLLSVLFTSSGGGPAKTRGAAFFIIAVICLLLFDNDDLMAKMAEHPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GHHDSALTHMLYTAIAFLGVADHKGGVLLLVLALCCKVGFHTASRKLSVDVGGAKRLQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS39 GHHDSALTHMLYTAIAFLGVADHKGGVLLLVLALCCKVGFHTASRKLSVDVGGAKRLQAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 SHLVSVLLLCPWVIVLSVTTESKVESWFSLIMPFATVIFFVMILDFYVDSICSVKMEVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS39 SHLVSVLLLCPWVIVLSVTTESKVESWFSLIMPFATVIFFVMILDFYVDSICSVKMEVSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 CARYGSFPIFISALLFGNFWTHPITDQLRAMNKAAHQESTEHVLSGGVVVSAIFFILSAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS39 CARYGSFPIFISALLFGNFWTHPITDQLRAMNKAAHQESTEHVLSGGVVVSAIFFILSAN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 ILSSPSKRGQKGTLIGYSPEGTPLYNFMGDAFQHSSQSIPRFIKESLKQILEESDSRQIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS39 ILSSPSKRGQKGTLIGYSPEGTPLYNFMGDAFQHSSQSIPRFIKESLKQILEESDSRQIF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 YFLCLNLLFTFVELFYGVLTNSLGLISDGFHMLFDCSALVMGLFAALMSRWKATRIFSYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS39 YFLCLNLLFTFVELFYGVLTNSLGLISDGFHMLFDCSALVMGLFAALMSRWKATRIFSYG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 YGRIEILSGFINGLFLIVIAFFVFMESVARLIDPPELDTHMLTPVSVGGLIVNLIGICAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS39 YGRIEILSGFINGLFLIVIAFFVFMESVARLIDPPELDTHMLTPVSVGGLIVNLIGICAF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 SHAHSHAHGASQGSCHSSDHSHSHHMHGHSDHGHGHSHGSAGGGMNANMRGVFLHVLADT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS39 SHAHSHAHGASQGSCHSSDHSHSHHMHGHSDHGHGHSHGSAGGGMNANMRGVFLHVLADT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 LGSIGVIVSTVLIEQFGWFIADPLCSLFIAILIFLSVVPLIKDACQVLLLRLPPEYEKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS39 LGSIGVIVSTVLIEQFGWFIADPLCSLFIAILIFLSVVPLIKDACQVLLLRLPPEYEKEL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 HIALEKIQKIEGLISYRDPHFWRHSASIVAGTIHIQVTSDVLEQRIVQQVTGILKDAGVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS39 HIALEKIQKIEGLISYRDPHFWRHSASIVAGTIHIQVTSDVLEQRIVQQVTGILKDAGVN 670 680 690 700 710 720 730 740 750 760 pF1KE0 NLTIQVEKEAYFQHMSGLSTGFHDVLAMTKQMESMKYCKDGTYIM ::::::::::::::::::::::::::::::::::::::::::::: CCDS39 NLTIQVEKEAYFQHMSGLSTGFHDVLAMTKQMESMKYCKDGTYIM 730 740 750 760 >>CCDS776.1 SLC30A7 gene_id:148867|Hs108|chr1 (376 aa) initn: 1103 init1: 510 opt: 642 Z-score: 735.9 bits: 145.9 E(32554): 1.1e-34 Smith-Waterman score: 1019; 44.0% identity (73.0% similar) in 348 aa overlap (407-727:26-372) 380 390 400 410 420 430 pF1KE0 YSPEGTPLYNFMGDAFQHSSQSIPRFIKESLKQILEESDSRQIFYFLCLNLLFTFVELFY ...:: .. ::..:.:::::: :.::::.: CCDS77 MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLY 10 20 30 40 50 440 450 460 470 480 490 pF1KE0 GVLTNSLGLISDGFHMLFDCSALVMGLFAALMSRWKATRIFSYGYGRIEILSGFINGLFL :. .: ::::::.:::.:: .:.. :: :...:.:. . ::::: : :.:.::.::::: CCDS77 GIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFL 60 70 80 90 100 110 500 510 520 530 540 550 pF1KE0 IVIAFFVFMESVARLIDPPELDTHMLTPVSVGGLIVNLIGICAFSHA-HSHAHGASQGSC : :::.: :.: : . ::.. . : ::. :..:::::: .:.:. :.:.::...: CCDS77 IFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFKHGGHGHSHGSGHGHS 120 130 140 150 160 170 560 570 580 pF1KE0 HS------------SDHSHSH-------HMHGHSDHGHGHSHGSAGGGMNAN-------M :: :: ::: : : :. ::::: :. : ... . . CCDS77 HSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHA-HGHGHFHSHDGPSLKETTGPSRQIL 180 190 200 210 220 230 590 600 610 620 630 640 pF1KE0 RGVFLHVLADTLGSIGVIVSTVLIEQFGWFIADPLCSLFIAILIFLSVVPLIKDACQVLL .:::::.:::::::::::.:......:: .::::.::..::::: .::.::.... .:. CCDS77 QGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILM 240 250 260 270 280 290 650 660 670 680 690 700 pF1KE0 LRLPPEYEKELHIALEKIQKIEGLISYRDPHFWRHSASIVAGTIHIQVTSDVLEQRIVQQ : :: :. : ...:...:. : .. ::: ... .::... :. :. . :..: CCDS77 QRTPPLLENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLIVAPDADARWILSQ 300 310 320 330 340 350 710 720 730 740 750 760 pF1KE0 VTGILKDAGVNNLTIQVEKEAYFQHMSGLSTGFHDVLAMTKQMESMKYCKDGTYIM . .:. .::: .: .:.. CCDS77 THNIFTQAGVRQLYVQIDFAAM 360 370 >>CCDS34173.1 SLC30A5 gene_id:64924|Hs108|chr5 (118 aa) initn: 618 init1: 600 opt: 602 Z-score: 697.8 bits: 137.2 E(32554): 1.5e-32 Smith-Waterman score: 602; 95.9% identity (96.9% similar) in 97 aa overlap (1-97:1-97) 10 20 30 40 50 60 pF1KE0 MEEKYGGDVLAGPGGGGGLGPVDVPSARLTKYIVLLCFTKFLKAVGLFESYDLLKAVHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MEEKYGGDVLAGPGGGGGLGPVDVPSARLTKYIVLLCFTKFLKAVGLFESYDLLKAVHIV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 QFIFILKLGTAFFMVLFQKPFSSGKTITKHQWIKIFKHAVAGCIISLLWFFGLTLCGPLR ::::::::::::::::::::::::::::::: : .: CCDS34 QFIFILKLGTAFFMVLFQKPFSSGKTITKHQIIGSLKIPGRKEFKDKKLNDPRKLVGN 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 TLLLFEHSDIVVISLLSVLFTSSGGGPAKTRGAAFFIIAVICLLLFDNDDLMAKMAEHPE >>CCDS31026.1 SLC30A10 gene_id:55532|Hs108|chr1 (485 aa) initn: 381 init1: 124 opt: 280 Z-score: 319.7 bits: 69.2 E(32554): 1.7e-11 Smith-Waterman score: 423; 28.4% identity (58.4% similar) in 377 aa overlap (418-727:10-383) 390 400 410 420 430 440 pF1KE0 MGDAFQHSSQSIPRFIKESLKQILEESDSRQIFYFLCLNLLFTFVELFYGVLTNSLGLIS .....: :.. : .:: : : ::..:.: CCDS31 MGRYSGKTCRLLFMLVLTVAFFVAELVSGYLGNSIALLS 10 20 30 450 460 470 480 490 500 pF1KE0 DGFHMLFDCSALVMGLFAALMSRWKATRIFS--YGYGRIEILSGFINGLFLIVIAFFVFM :.:.:: : .: .:: :. ..: . :: :: :::.: :..... :..:: .. : .:. CCDS31 DSFNMLSDLISLCVGLSAGYIAR-RPTRGFSATYGYARAEVVGALSNAVFLTALCFTIFV 40 50 60 70 80 90 510 520 530 540 pF1KE0 ESVARLIDPPELDT-HMLTPVSVGGLIVNLIGI-----CA--FS---HAHSH-------- :.: :: : ..: ... :.: ::.::..:. :: :. ...:. CCDS31 EAVLRLARPERIDDPELVLIVGVLGLLVNVVGLLIFQDCAAWFACCLRGRSRRLQQRQQL 100 110 120 130 140 150 550 560 570 580 pF1KE0 -------AHGASQGSC---HSSDHSHSHH-----MHGHS-----DHGHGHSHGSAGGGMN : :. ::. ...: . ..: : ..: . :: ..: CCDS31 AEGCVPGAFGGPQGAEDPRRAADPTAPGSDSAVTLRGTSVERKREKGATVFANVAGDSFN 160 170 180 190 200 210 590 600 610 620 pF1KE0 A-----------------NMRGVFLHVLADTLGSIGVIVSTVLI--------EQFGW-FI . :.:::.:::..:.:::. :....... . .: CCDS31 TQNEPEDMMKKEKKSEALNIRGVLLHVMGDALGSVVVVITAIIFYVLPLKSEDPCNWQCY 220 230 240 250 260 270 630 640 650 660 670 680 pF1KE0 ADPLCSLFIAILIFLSVVPLIKDACQVLLLRLPPEYEKELHIALEKIQKIEGLISYRDPH :: .....:.:. :. ::::.. .:: .: . : .. :.. . :. : .. : CCDS31 IDPSLTVLMVIIILSSAFPLIKETAAILLQMVPKGVNMEELMS--KLSAVPGISSVHEVH 280 290 300 310 320 330 690 700 710 720 730 740 pF1KE0 FWRHSASIVAGTIHIQVTSDVLEQRIVQQVTGILKDAGVNNLTIQVEKEAYFQHMSGLST .:. .. . .:.::. .: : .. :.. ::..:.::: : CCDS31 IWELVSGKIIATLHIKYPKDRGYQDASTKIREIFHHAGIHNVTIQFENVDLKEPLEQKDL 340 350 360 370 380 390 750 760 pF1KE0 GFHDVLAMTKQMESMKYCKDGTYIM CCDS31 LLLCNSPCISKGCAKQLCCPPGALPLAHVNGCAEHNGGPSLDTYGSDGLSRRDAREVAIE 400 410 420 430 440 450 765 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 13:00:06 2016 done: Thu Nov 3 13:00:06 2016 Total Scan time: 3.940 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]