Result of FASTA (omim) for
pF1KE0388
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0388, 610 aa
1>>>pF1KE0388 610 - 610 aa - 610 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.3150+/-0.000442; mu= 7.9839+/- 0.028
mean_var=387.0606+/-91.416, 0's: 0 Z-trim(119.6): 681 B-trim: 1856 in 1/53
Lambda= 0.065191
statistics sampled from 33124 (33888) to 33124 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.397), width: 16
Scan time: 12.250
The best scores are: opt bits E(85289)
NP_001005861 (OMIM: 600524) tyrosine-protein kinas ( 610) 4036 394.5 5.6e-109
NP_002949 (OMIM: 600524) tyrosine-protein kinase R ( 607) 4002 391.3 5.1e-108
XP_016862505 (OMIM: 600524) PREDICTED: tyrosine-pr ( 411) 2296 230.6 8.3e-60
NP_001305842 (OMIM: 600168,617075) macrophage-stim (1294) 743 85.3 1.4e-15
XP_011532046 (OMIM: 600168,617075) PREDICTED: macr (1295) 743 85.3 1.4e-15
NP_001231866 (OMIM: 600168,617075) macrophage-stim (1351) 743 85.3 1.5e-15
XP_011532042 (OMIM: 600168,617075) PREDICTED: macr (1352) 743 85.3 1.5e-15
XP_011532041 (OMIM: 600168,617075) PREDICTED: macr (1361) 743 85.3 1.5e-15
NP_002438 (OMIM: 600168,617075) macrophage-stimula (1400) 743 85.3 1.5e-15
XP_005265227 (OMIM: 600168,617075) PREDICTED: macr (1401) 743 85.3 1.5e-15
XP_016858654 (OMIM: 604705,613862) PREDICTED: tyro ( 594) 735 84.0 1.6e-15
XP_016858653 (OMIM: 604705,613862) PREDICTED: tyro ( 936) 735 84.3 2e-15
XP_011508792 (OMIM: 604705,613862) PREDICTED: tyro ( 936) 735 84.3 2e-15
NP_006334 (OMIM: 604705,613862) tyrosine-protein k ( 999) 735 84.4 2.1e-15
NP_001311331 (OMIM: 114550,164860,605074,607278,61 ( 960) 733 84.1 2.3e-15
XP_006716053 (OMIM: 114550,164860,605074,607278,61 ( 960) 733 84.1 2.3e-15
NP_000236 (OMIM: 114550,164860,605074,607278,61670 (1390) 733 84.4 2.9e-15
NP_001120972 (OMIM: 114550,164860,605074,607278,61 (1408) 733 84.4 2.9e-15
XP_011514525 (OMIM: 114550,164860,605074,607278,61 (1409) 733 84.4 2.9e-15
NP_001265528 (OMIM: 109135) tyrosine-protein kinas ( 626) 695 80.3 2.2e-14
NP_001690 (OMIM: 109135) tyrosine-protein kinase r ( 885) 695 80.5 2.7e-14
NP_068713 (OMIM: 109135) tyrosine-protein kinase r ( 894) 695 80.5 2.7e-14
XP_011532043 (OMIM: 600168,617075) PREDICTED: macr (1332) 693 80.6 3.8e-14
NP_001317193 (OMIM: 600341) tyrosine-protein kinas ( 845) 673 78.4 1.1e-13
NP_006284 (OMIM: 600341) tyrosine-protein kinase r ( 890) 673 78.4 1.1e-13
XP_005263622 (OMIM: 604705,613862) PREDICTED: tyro ( 832) 657 76.9 3.1e-13
XP_011526291 (OMIM: 147670,246200,262190,609968,61 (1369) 644 76.0 9.4e-13
NP_001073285 (OMIM: 147670,246200,262190,609968,61 (1370) 644 76.0 9.4e-13
XP_011526290 (OMIM: 147670,246200,262190,609968,61 (1381) 644 76.0 9.4e-13
NP_000199 (OMIM: 147670,246200,262190,609968,61054 (1382) 644 76.0 9.4e-13
XP_016870241 (OMIM: 600456,613886) PREDICTED: BDNF ( 822) 637 75.0 1.1e-12
NP_001018074 (OMIM: 600456,613886) BDNF/NT-3 growt ( 822) 637 75.0 1.1e-12
XP_016870242 (OMIM: 600456,613886) PREDICTED: BDNF ( 822) 637 75.0 1.1e-12
XP_016870243 (OMIM: 600456,613886) PREDICTED: BDNF ( 822) 637 75.0 1.1e-12
XP_011517020 (OMIM: 600456,613886) PREDICTED: BDNF ( 822) 637 75.0 1.1e-12
XP_011519819 (OMIM: 147370,270450) PREDICTED: insu ( 922) 629 74.3 2e-12
XP_011519818 (OMIM: 147370,270450) PREDICTED: insu (1064) 629 74.4 2.2e-12
XP_016877628 (OMIM: 147370,270450) PREDICTED: insu (1246) 629 74.5 2.4e-12
NP_001278787 (OMIM: 147370,270450) insulin-like gr (1366) 629 74.6 2.5e-12
NP_000866 (OMIM: 147370,270450) insulin-like growt (1367) 629 74.6 2.5e-12
XP_016877627 (OMIM: 147370,270450) PREDICTED: insu (1391) 629 74.6 2.5e-12
XP_016877626 (OMIM: 147370,270450) PREDICTED: insu (1392) 629 74.6 2.5e-12
XP_016877625 (OMIM: 147370,270450) PREDICTED: insu (1392) 629 74.6 2.5e-12
XP_011534355 (OMIM: 165020) PREDICTED: proto-oncog (2299) 622 74.3 5.2e-12
XP_016866662 (OMIM: 165020) PREDICTED: proto-oncog (2333) 622 74.3 5.3e-12
XP_016866661 (OMIM: 165020) PREDICTED: proto-oncog (2334) 622 74.3 5.3e-12
XP_006715611 (OMIM: 165020) PREDICTED: proto-oncog (2342) 622 74.3 5.3e-12
XP_011534354 (OMIM: 165020) PREDICTED: proto-oncog (2343) 622 74.3 5.3e-12
NP_002935 (OMIM: 165020) proto-oncogene tyrosine-p (2347) 622 74.3 5.3e-12
XP_011534353 (OMIM: 165020) PREDICTED: proto-oncog (2348) 622 74.3 5.3e-12
>>NP_001005861 (OMIM: 600524) tyrosine-protein kinase RY (610 aa)
initn: 4036 init1: 4036 opt: 4036 Z-score: 2077.5 bits: 394.5 E(85289): 5.6e-109
Smith-Waterman score: 4036; 100.0% identity (100.0% similar) in 610 aa overlap (1-610:1-610)
10 20 30 40 50 60
pF1KE0 MRGAARLGRPGRSCLPGARGLRAPPPPPLLLLLALLPLLPAPGAAAAPAPRPPELQSASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRGAARLGRPGRSCLPGARGLRAPPPPPLLLLLALLPLLPAPGAAAAPAPRPPELQSASA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GPSVSLYLSEDEVRRLIGLDAELYYVRNDLISHYALSFSLLVPSETNFLHFTWHAKSKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPSVSLYLSEDEVRRLIGLDAELYYVRNDLISHYALSFSLLVPSETNFLHFTWHAKSKVE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 YKLGFQVDNVLAMDMPQVNISVQGEVPRTLSVFRVELSCTGKVDSEVMILMQLNLTVNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKLGFQVDNVLAMDMPQVNISVQGEVPRTLSVFRVELSCTGKVDSEVMILMQLNLTVNSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 KNFTVLNFKRRKMCYKKLEEVKTSALDKNTSRTIYDPVHAAPTTSTRVFYISVGVCCAVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNFTVLNFKRRKMCYKKLEEVKTSALDKNTSRTIYDPVHAAPTTSTRVFYISVGVCCAVI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 FLVAIILAVLHLHSMKRIELDDSISASSSSQGLSQPSTQTTQYLRADTPNNATPITSSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLVAIILAVLHLHSMKRIELDDSISASSSSQGLSQPSTQTTQYLRADTPNNATPITSSLG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 YPTLRIEKNDLRSVTLLEAKGKVKDIAISRERITLKDVLQEGTFGRIFHGILIDEKDPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPTLRIEKNDLRSVTLLEAKGKVKDIAISRERITLKDVLQEGTFGRIFHGILIDEKDPNK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 EKQAFVKTVKDQASEIQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPMVILPYMNWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKQAFVKTVKDQASEIQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPMVILPYMNWG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 NLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARNCVIDDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARNCVIDDTL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 QVKITDNALSRDLFPMDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVKITDNALSRDLFPMDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 LGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLT
550 560 570 580 590 600
610
pF1KE0 EFHAALGAYV
::::::::::
NP_001 EFHAALGAYV
610
>>NP_002949 (OMIM: 600524) tyrosine-protein kinase RYK i (607 aa)
initn: 2103 init1: 2103 opt: 4002 Z-score: 2060.2 bits: 391.3 E(85289): 5.1e-108
Smith-Waterman score: 4002; 99.5% identity (99.5% similar) in 610 aa overlap (1-610:1-607)
10 20 30 40 50 60
pF1KE0 MRGAARLGRPGRSCLPGARGLRAPPPPPLLLLLALLPLLPAPGAAAAPAPRPPELQSASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MRGAARLGRPGRSCLPGARGLRAPPPPPLLLLLALLPLLPAPGAAAAPAPRPPELQSASA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GPSVSLYLSEDEVRRLIGLDAELYYVRNDLISHYALSFSLLVPSETNFLHFTWHAKSKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GPSVSLYLSEDEVRRLIGLDAELYYVRNDLISHYALSFSLLVPSETNFLHFTWHAKSKVE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 YKLGFQVDNVLAMDMPQVNISVQGEVPRTLSVFRVELSCTGKVDSEVMILMQLNLTVNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YKLGFQVDNVLAMDMPQVNISVQGEVPRTLSVFRVELSCTGKVDSEVMILMQLNLTVNSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 KNFTVLNFKRRKMCYKKLEEVKTSALDKNTSRTIYDPVHAAPTTSTRVFYISVGVCCAVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KNFTVLNFKRRKMCYKKLEEVKTSALDKNTSRTIYDPVHAAPTTSTRVFYISVGVCCAVI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 FLVAIILAVLHLHSMKRIELDDSISASSSSQGLSQPSTQTTQYLRADTPNNATPITSSLG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FLVAIILAVLHLHSMKRIELDDSISASSSSQGLSQPSTQTTQYLRADTPNNATPITS---
250 260 270 280 290
310 320 330 340 350 360
pF1KE0 YPTLRIEKNDLRSVTLLEAKGKVKDIAISRERITLKDVLQEGTFGRIFHGILIDEKDPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YPTLRIEKNDLRSVTLLEAKGKVKDIAISRERITLKDVLQEGTFGRIFHGILIDEKDPNK
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE0 EKQAFVKTVKDQASEIQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPMVILPYMNWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EKQAFVKTVKDQASEIQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPMVILPYMNWG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE0 NLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARNCVIDDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARNCVIDDTL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE0 QVKITDNALSRDLFPMDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QVKITDNALSRDLFPMDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMT
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE0 LGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLT
540 550 560 570 580 590
610
pF1KE0 EFHAALGAYV
::::::::::
NP_002 EFHAALGAYV
600
>>XP_016862505 (OMIM: 600524) PREDICTED: tyrosine-protei (411 aa)
initn: 2103 init1: 2103 opt: 2296 Z-score: 1194.7 bits: 230.6 E(85289): 8.3e-60
Smith-Waterman score: 2296; 98.6% identity (98.6% similar) in 351 aa overlap (260-610:64-411)
230 240 250 260 270 280
pF1KE0 YISVGVCCAVIFLVAIILAVLHLHSMKRIELDDSISASSSSQGLSQPSTQTTQYLRADTP
: :::::::::::::::::::::::::::
XP_016 PTAFKRHLLLLSLHRGHWDYHLLSVFCLPVLYPSISASSSSQGLSQPSTQTTQYLRADTP
40 50 60 70 80 90
290 300 310 320 330 340
pF1KE0 NNATPITSSLGYPTLRIEKNDLRSVTLLEAKGKVKDIAISRERITLKDVLQEGTFGRIFH
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNATPITS---YPTLRIEKNDLRSVTLLEAKGKVKDIAISRERITLKDVLQEGTFGRIFH
100 110 120 130 140 150
350 360 370 380 390 400
pF1KE0 GILIDEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GILIDEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEK
160 170 180 190 200 210
410 420 430 440 450 460
pF1KE0 PMVILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMVILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDL
220 230 240 250 260 270
470 480 490 500 510 520
pF1KE0 AARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENRPVRWMALESLVNNEFSSASDVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENRPVRWMALESLVNNEFSSASDVW
280 290 300 310 320 330
530 540 550 560 570 580
pF1KE0 AFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEER
340 350 360 370 380 390
590 600 610
pF1KE0 PKFQQLVQCLTEFHAALGAYV
:::::::::::::::::::::
XP_016 PKFQQLVQCLTEFHAALGAYV
400 410
>>NP_001305842 (OMIM: 600168,617075) macrophage-stimulat (1294 aa)
initn: 700 init1: 371 opt: 743 Z-score: 400.5 bits: 85.3 E(85289): 1.4e-15
Smith-Waterman score: 743; 40.0% identity (67.4% similar) in 310 aa overlap (302-606:944-1242)
280 290 300 310 320 330
pF1KE0 GLSQPSTQTTQYLRADTPNNATPITSSLGYPTLRIEKNDLRSV-TLLEAKGKVKDIAISR
: :: :. .::.. . : :. :::. : .
NP_001 GLALPAIDGLDSTTCVHGASFSDSEDESCVPLLRKESIQLRDLDSALLAE--VKDVLIPH
920 930 940 950 960 970
340 350 360 370 380
pF1KE0 ERI-TLKD-VLQEGTFGRIFHGILIDEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCKL
::. : .: :. .: :: ..:: ::. ... : .:... . :: .: :. .
NP_001 ERVVTHSDRVIGKGHFGVVYHGEYIDQA--QNRIQCAIKSLSRITEMQQVEAFLREGLLM
980 990 1000 1010 1020
390 400 410 420 430 440
pF1KE0 RGLHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHM
:::.: :.: . . . : :.:::: :.: :.:. . :: . .::. .
NP_001 RGLNHPNVLALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQ----RNPTV---KDLISF
1030 1040 1050 1060 1070 1080
450 460 470 480 490 500
pF1KE0 AIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENR-
..:.: :: :::... .:.:::::::..:... ::..: .:.::.. .:. . ....
NP_001 GLQVARGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHAR
1090 1100 1110 1120 1130 1140
510 520 530 540 550 560
pF1KE0 -PVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQ
::.::::::: . .:.. ::::.::: ::::.: : :: ::::... .: .: :. :
NP_001 LPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQ
1150 1160 1170 1180 1190 1200
570 580 590 600 610
pF1KE0 PINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALGAYV
: ::: :. :: :: :: :: :. :: . .. .::
NP_001 PEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPSTS
1210 1220 1230 1240 1250 1260
NP_001 HEMNVRPEQPQFSPMPGNVRRPRPLSEPPRPT
1270 1280 1290
>>XP_011532046 (OMIM: 600168,617075) PREDICTED: macropha (1295 aa)
initn: 700 init1: 371 opt: 743 Z-score: 400.5 bits: 85.3 E(85289): 1.4e-15
Smith-Waterman score: 743; 40.0% identity (67.4% similar) in 310 aa overlap (302-606:945-1243)
280 290 300 310 320 330
pF1KE0 GLSQPSTQTTQYLRADTPNNATPITSSLGYPTLRIEKNDLRSV-TLLEAKGKVKDIAISR
: :: :. .::.. . : :. :::. : .
XP_011 GLALPAIDGLDSTTCVHGASFSDSEDESCVPLLRKESIQLRDLDSALLAE--VKDVLIPH
920 930 940 950 960 970
340 350 360 370 380
pF1KE0 ERI-TLKD-VLQEGTFGRIFHGILIDEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCKL
::. : .: :. .: :: ..:: ::. ... : .:... . :: .: :. .
XP_011 ERVVTHSDRVIGKGHFGVVYHGEYIDQA--QNRIQCAIKSLSRITEMQQVEAFLREGLLM
980 990 1000 1010 1020 1030
390 400 410 420 430 440
pF1KE0 RGLHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHM
:::.: :.: . . . : :.:::: :.: :.:. . :: . .::. .
XP_011 RGLNHPNVLALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQ----RNPTV---KDLISF
1040 1050 1060 1070 1080
450 460 470 480 490 500
pF1KE0 AIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENR-
..:.: :: :::... .:.:::::::..:... ::..: .:.::.. .:. . ....
XP_011 GLQVARGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHAR
1090 1100 1110 1120 1130 1140
510 520 530 540 550 560
pF1KE0 -PVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQ
::.::::::: . .:.. ::::.::: ::::.: : :: ::::... .: .: :. :
XP_011 LPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQ
1150 1160 1170 1180 1190 1200
570 580 590 600 610
pF1KE0 PINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALGAYV
: ::: :. :: :: :: :: :. :: . .. .::
XP_011 PEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPSTS
1210 1220 1230 1240 1250 1260
XP_011 HEMNVRPEQPQFSPMPGNVRRPRPLSEPPRPT
1270 1280 1290
>>NP_001231866 (OMIM: 600168,617075) macrophage-stimulat (1351 aa)
initn: 700 init1: 371 opt: 743 Z-score: 400.3 bits: 85.3 E(85289): 1.5e-15
Smith-Waterman score: 743; 40.0% identity (67.4% similar) in 310 aa overlap (302-606:1001-1299)
280 290 300 310 320 330
pF1KE0 GLSQPSTQTTQYLRADTPNNATPITSSLGYPTLRIEKNDLRSV-TLLEAKGKVKDIAISR
: :: :. .::.. . : :. :::. : .
NP_001 GLALPAIDGLDSTTCVHGASFSDSEDESCVPLLRKESIQLRDLDSALLAE--VKDVLIPH
980 990 1000 1010 1020
340 350 360 370 380
pF1KE0 ERI-TLKD-VLQEGTFGRIFHGILIDEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCKL
::. : .: :. .: :: ..:: ::. ... : .:... . :: .: :. .
NP_001 ERVVTHSDRVIGKGHFGVVYHGEYIDQA--QNRIQCAIKSLSRITEMQQVEAFLREGLLM
1030 1040 1050 1060 1070 1080
390 400 410 420 430 440
pF1KE0 RGLHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHM
:::.: :.: . . . : :.:::: :.: :.:. . :: . .::. .
NP_001 RGLNHPNVLALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQ----RNPTV---KDLISF
1090 1100 1110 1120 1130
450 460 470 480 490 500
pF1KE0 AIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENR-
..:.: :: :::... .:.:::::::..:... ::..: .:.::.. .:. . ....
NP_001 GLQVARGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHAR
1140 1150 1160 1170 1180 1190
510 520 530 540 550 560
pF1KE0 -PVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQ
::.::::::: . .:.. ::::.::: ::::.: : :: ::::... .: .: :. :
NP_001 LPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQ
1200 1210 1220 1230 1240 1250
570 580 590 600 610
pF1KE0 PINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALGAYV
: ::: :. :: :: :: :: :. :: . .. .::
NP_001 PEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPSTS
1260 1270 1280 1290 1300 1310
NP_001 HEMNVRPEQPQFSPMPGNVRRPRPLSEPPRPT
1320 1330 1340 1350
>>XP_011532042 (OMIM: 600168,617075) PREDICTED: macropha (1352 aa)
initn: 700 init1: 371 opt: 743 Z-score: 400.3 bits: 85.3 E(85289): 1.5e-15
Smith-Waterman score: 743; 40.0% identity (67.4% similar) in 310 aa overlap (302-606:1002-1300)
280 290 300 310 320 330
pF1KE0 GLSQPSTQTTQYLRADTPNNATPITSSLGYPTLRIEKNDLRSV-TLLEAKGKVKDIAISR
: :: :. .::.. . : :. :::. : .
XP_011 GLALPAIDGLDSTTCVHGASFSDSEDESCVPLLRKESIQLRDLDSALLAE--VKDVLIPH
980 990 1000 1010 1020
340 350 360 370 380
pF1KE0 ERI-TLKD-VLQEGTFGRIFHGILIDEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCKL
::. : .: :. .: :: ..:: ::. ... : .:... . :: .: :. .
XP_011 ERVVTHSDRVIGKGHFGVVYHGEYIDQA--QNRIQCAIKSLSRITEMQQVEAFLREGLLM
1030 1040 1050 1060 1070 1080
390 400 410 420 430 440
pF1KE0 RGLHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHM
:::.: :.: . . . : :.:::: :.: :.:. . :: . .::. .
XP_011 RGLNHPNVLALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQ----RNPTV---KDLISF
1090 1100 1110 1120 1130 1140
450 460 470 480 490 500
pF1KE0 AIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENR-
..:.: :: :::... .:.:::::::..:... ::..: .:.::.. .:. . ....
XP_011 GLQVARGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHAR
1150 1160 1170 1180 1190 1200
510 520 530 540 550 560
pF1KE0 -PVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQ
::.::::::: . .:.. ::::.::: ::::.: : :: ::::... .: .: :. :
XP_011 LPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQ
1210 1220 1230 1240 1250 1260
570 580 590 600 610
pF1KE0 PINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALGAYV
: ::: :. :: :: :: :: :. :: . .. .::
XP_011 PEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPSTS
1270 1280 1290 1300 1310 1320
XP_011 HEMNVRPEQPQFSPMPGNVRRPRPLSEPPRPT
1330 1340 1350
>>XP_011532041 (OMIM: 600168,617075) PREDICTED: macropha (1361 aa)
initn: 700 init1: 371 opt: 743 Z-score: 400.3 bits: 85.3 E(85289): 1.5e-15
Smith-Waterman score: 743; 40.0% identity (67.4% similar) in 310 aa overlap (302-606:1011-1309)
280 290 300 310 320 330
pF1KE0 GLSQPSTQTTQYLRADTPNNATPITSSLGYPTLRIEKNDLRSV-TLLEAKGKVKDIAISR
: :: :. .::.. . : :. :::. : .
XP_011 GLALPAIDGLDSTTCVHGASFSDSEDESCVPLLRKESIQLRDLDSALLAE--VKDVLIPH
990 1000 1010 1020 1030
340 350 360 370 380
pF1KE0 ERI-TLKD-VLQEGTFGRIFHGILIDEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCKL
::. : .: :. .: :: ..:: ::. ... : .:... . :: .: :. .
XP_011 ERVVTHSDRVIGKGHFGVVYHGEYIDQA--QNRIQCAIKSLSRITEMQQVEAFLREGLLM
1040 1050 1060 1070 1080 1090
390 400 410 420 430 440
pF1KE0 RGLHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHM
:::.: :.: . . . : :.:::: :.: :.:. . :: . .::. .
XP_011 RGLNHPNVLALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQ----RNPTV---KDLISF
1100 1110 1120 1130 1140
450 460 470 480 490 500
pF1KE0 AIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENR-
..:.: :: :::... .:.:::::::..:... ::..: .:.::.. .:. . ....
XP_011 GLQVARGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHAR
1150 1160 1170 1180 1190 1200
510 520 530 540 550 560
pF1KE0 -PVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQ
::.::::::: . .:.. ::::.::: ::::.: : :: ::::... .: .: :. :
XP_011 LPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQ
1210 1220 1230 1240 1250 1260
570 580 590 600 610
pF1KE0 PINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALGAYV
: ::: :. :: :: :: :: :. :: . .. .::
XP_011 PEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPSTS
1270 1280 1290 1300 1310 1320
XP_011 HEMNVRPEQPQFSPMPGNVRRPRPLSEPPRPT
1330 1340 1350 1360
>>NP_002438 (OMIM: 600168,617075) macrophage-stimulating (1400 aa)
initn: 700 init1: 371 opt: 743 Z-score: 400.2 bits: 85.3 E(85289): 1.5e-15
Smith-Waterman score: 743; 40.0% identity (67.4% similar) in 310 aa overlap (302-606:1050-1348)
280 290 300 310 320 330
pF1KE0 GLSQPSTQTTQYLRADTPNNATPITSSLGYPTLRIEKNDLRSV-TLLEAKGKVKDIAISR
: :: :. .::.. . : :. :::. : .
NP_002 GLALPAIDGLDSTTCVHGASFSDSEDESCVPLLRKESIQLRDLDSALLAE--VKDVLIPH
1020 1030 1040 1050 1060 1070
340 350 360 370 380
pF1KE0 ERI-TLKD-VLQEGTFGRIFHGILIDEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCKL
::. : .: :. .: :: ..:: ::. ... : .:... . :: .: :. .
NP_002 ERVVTHSDRVIGKGHFGVVYHGEYIDQA--QNRIQCAIKSLSRITEMQQVEAFLREGLLM
1080 1090 1100 1110 1120 1130
390 400 410 420 430 440
pF1KE0 RGLHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHM
:::.: :.: . . . : :.:::: :.: :.:. . :: . .::. .
NP_002 RGLNHPNVLALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQ----RNPTV---KDLISF
1140 1150 1160 1170 1180
450 460 470 480 490 500
pF1KE0 AIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENR-
..:.: :: :::... .:.:::::::..:... ::..: .:.::.. .:. . ....
NP_002 GLQVARGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHAR
1190 1200 1210 1220 1230 1240
510 520 530 540 550 560
pF1KE0 -PVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQ
::.::::::: . .:.. ::::.::: ::::.: : :: ::::... .: .: :. :
NP_002 LPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQ
1250 1260 1270 1280 1290 1300
570 580 590 600 610
pF1KE0 PINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALGAYV
: ::: :. :: :: :: :: :. :: . .. .::
NP_002 PEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPSTS
1310 1320 1330 1340 1350 1360
NP_002 HEMNVRPEQPQFSPMPGNVRRPRPLSEPPRPT
1370 1380 1390 1400
>>XP_005265227 (OMIM: 600168,617075) PREDICTED: macropha (1401 aa)
initn: 700 init1: 371 opt: 743 Z-score: 400.2 bits: 85.3 E(85289): 1.5e-15
Smith-Waterman score: 743; 40.0% identity (67.4% similar) in 310 aa overlap (302-606:1051-1349)
280 290 300 310 320 330
pF1KE0 GLSQPSTQTTQYLRADTPNNATPITSSLGYPTLRIEKNDLRSV-TLLEAKGKVKDIAISR
: :: :. .::.. . : :. :::. : .
XP_005 GLALPAIDGLDSTTCVHGASFSDSEDESCVPLLRKESIQLRDLDSALLAE--VKDVLIPH
1030 1040 1050 1060 1070
340 350 360 370 380
pF1KE0 ERI-TLKD-VLQEGTFGRIFHGILIDEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCKL
::. : .: :. .: :: ..:: ::. ... : .:... . :: .: :. .
XP_005 ERVVTHSDRVIGKGHFGVVYHGEYIDQA--QNRIQCAIKSLSRITEMQQVEAFLREGLLM
1080 1090 1100 1110 1120 1130
390 400 410 420 430 440
pF1KE0 RGLHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHM
:::.: :.: . . . : :.:::: :.: :.:. . :: . .::. .
XP_005 RGLNHPNVLALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQ----RNPTV---KDLISF
1140 1150 1160 1170 1180
450 460 470 480 490 500
pF1KE0 AIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENR-
..:.: :: :::... .:.:::::::..:... ::..: .:.::.. .:. . ....
XP_005 GLQVARGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHAR
1190 1200 1210 1220 1230 1240
510 520 530 540 550 560
pF1KE0 -PVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQ
::.::::::: . .:.. ::::.::: ::::.: : :: ::::... .: .: :. :
XP_005 LPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQ
1250 1260 1270 1280 1290 1300
570 580 590 600 610
pF1KE0 PINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALGAYV
: ::: :. :: :: :: :: :. :: . .. .::
XP_005 PEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPSTS
1310 1320 1330 1340 1350 1360
XP_005 HEMNVRPEQPQFSPMPGNVRRPRPLSEPPRPT
1370 1380 1390 1400
610 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 12:51:58 2016 done: Thu Nov 3 12:52:00 2016
Total Scan time: 12.250 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]