FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0401, 205 aa 1>>>pF1KE0401 205 - 205 aa - 205 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6861+/-0.00039; mu= 2.5238+/- 0.024 mean_var=123.4404+/-24.938, 0's: 0 Z-trim(115.9): 9 B-trim: 107 in 2/53 Lambda= 0.115437 statistics sampled from 26720 (26729) to 26720 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.313), width: 16 Scan time: 5.800 The best scores are: opt bits E(85289) NP_001245149 (OMIM: 609178) protein MIS12 homolog ( 205) 1351 235.6 4.2e-62 NP_001245147 (OMIM: 609178) protein MIS12 homolog ( 205) 1351 235.6 4.2e-62 XP_016880522 (OMIM: 609178) PREDICTED: protein MIS ( 205) 1351 235.6 4.2e-62 NP_001245146 (OMIM: 609178) protein MIS12 homolog ( 205) 1351 235.6 4.2e-62 XP_016880524 (OMIM: 609178) PREDICTED: protein MIS ( 205) 1351 235.6 4.2e-62 NP_001245148 (OMIM: 609178) protein MIS12 homolog ( 205) 1351 235.6 4.2e-62 XP_005256854 (OMIM: 609178) PREDICTED: protein MIS ( 205) 1351 235.6 4.2e-62 XP_016880523 (OMIM: 609178) PREDICTED: protein MIS ( 205) 1351 235.6 4.2e-62 NP_076944 (OMIM: 609178) protein MIS12 homolog [Ho ( 205) 1351 235.6 4.2e-62 >>NP_001245149 (OMIM: 609178) protein MIS12 homolog [Hom (205 aa) initn: 1351 init1: 1351 opt: 1351 Z-score: 1235.9 bits: 235.6 E(85289): 4.2e-62 Smith-Waterman score: 1351; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KE0 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS 130 140 150 160 170 180 190 200 pF1KE0 LVQNSRKLQNIRDNVEKESKRLKIS ::::::::::::::::::::::::: NP_001 LVQNSRKLQNIRDNVEKESKRLKIS 190 200 >>NP_001245147 (OMIM: 609178) protein MIS12 homolog [Hom (205 aa) initn: 1351 init1: 1351 opt: 1351 Z-score: 1235.9 bits: 235.6 E(85289): 4.2e-62 Smith-Waterman score: 1351; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KE0 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS 130 140 150 160 170 180 190 200 pF1KE0 LVQNSRKLQNIRDNVEKESKRLKIS ::::::::::::::::::::::::: NP_001 LVQNSRKLQNIRDNVEKESKRLKIS 190 200 >>XP_016880522 (OMIM: 609178) PREDICTED: protein MIS12 h (205 aa) initn: 1351 init1: 1351 opt: 1351 Z-score: 1235.9 bits: 235.6 E(85289): 4.2e-62 Smith-Waterman score: 1351; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KE0 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS 130 140 150 160 170 180 190 200 pF1KE0 LVQNSRKLQNIRDNVEKESKRLKIS ::::::::::::::::::::::::: XP_016 LVQNSRKLQNIRDNVEKESKRLKIS 190 200 >>NP_001245146 (OMIM: 609178) protein MIS12 homolog [Hom (205 aa) initn: 1351 init1: 1351 opt: 1351 Z-score: 1235.9 bits: 235.6 E(85289): 4.2e-62 Smith-Waterman score: 1351; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KE0 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS 130 140 150 160 170 180 190 200 pF1KE0 LVQNSRKLQNIRDNVEKESKRLKIS ::::::::::::::::::::::::: NP_001 LVQNSRKLQNIRDNVEKESKRLKIS 190 200 >>XP_016880524 (OMIM: 609178) PREDICTED: protein MIS12 h (205 aa) initn: 1351 init1: 1351 opt: 1351 Z-score: 1235.9 bits: 235.6 E(85289): 4.2e-62 Smith-Waterman score: 1351; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KE0 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS 130 140 150 160 170 180 190 200 pF1KE0 LVQNSRKLQNIRDNVEKESKRLKIS ::::::::::::::::::::::::: XP_016 LVQNSRKLQNIRDNVEKESKRLKIS 190 200 >>NP_001245148 (OMIM: 609178) protein MIS12 homolog [Hom (205 aa) initn: 1351 init1: 1351 opt: 1351 Z-score: 1235.9 bits: 235.6 E(85289): 4.2e-62 Smith-Waterman score: 1351; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KE0 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS 130 140 150 160 170 180 190 200 pF1KE0 LVQNSRKLQNIRDNVEKESKRLKIS ::::::::::::::::::::::::: NP_001 LVQNSRKLQNIRDNVEKESKRLKIS 190 200 >>XP_005256854 (OMIM: 609178) PREDICTED: protein MIS12 h (205 aa) initn: 1351 init1: 1351 opt: 1351 Z-score: 1235.9 bits: 235.6 E(85289): 4.2e-62 Smith-Waterman score: 1351; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KE0 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS 130 140 150 160 170 180 190 200 pF1KE0 LVQNSRKLQNIRDNVEKESKRLKIS ::::::::::::::::::::::::: XP_005 LVQNSRKLQNIRDNVEKESKRLKIS 190 200 >>XP_016880523 (OMIM: 609178) PREDICTED: protein MIS12 h (205 aa) initn: 1351 init1: 1351 opt: 1351 Z-score: 1235.9 bits: 235.6 E(85289): 4.2e-62 Smith-Waterman score: 1351; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KE0 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS 130 140 150 160 170 180 190 200 pF1KE0 LVQNSRKLQNIRDNVEKESKRLKIS ::::::::::::::::::::::::: XP_016 LVQNSRKLQNIRDNVEKESKRLKIS 190 200 >>NP_076944 (OMIM: 609178) protein MIS12 homolog [Homo s (205 aa) initn: 1351 init1: 1351 opt: 1351 Z-score: 1235.9 bits: 235.6 E(85289): 4.2e-62 Smith-Waterman score: 1351; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KE0 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 RKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 IEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVS 130 140 150 160 170 180 190 200 pF1KE0 LVQNSRKLQNIRDNVEKESKRLKIS ::::::::::::::::::::::::: NP_076 LVQNSRKLQNIRDNVEKESKRLKIS 190 200 205 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:21:09 2016 done: Thu Nov 3 12:21:10 2016 Total Scan time: 5.800 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]