FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0405, 298 aa 1>>>pF1KE0405 298 - 298 aa - 298 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5350+/-0.000353; mu= 14.8583+/- 0.022 mean_var=103.3857+/-22.195, 0's: 0 Z-trim(116.3): 182 B-trim: 1266 in 1/53 Lambda= 0.126137 statistics sampled from 27078 (27390) to 27078 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.321), width: 16 Scan time: 7.550 The best scores are: opt bits E(85289) NP_054776 (OMIM: 602383) mimecan isoform 2 precurs ( 298) 1946 364.6 1.3e-100 NP_148935 (OMIM: 602383) mimecan isoform 2 precurs ( 298) 1946 364.6 1.3e-100 NP_077727 (OMIM: 602383) mimecan isoform 1 [Homo s ( 356) 1933 362.3 7.8e-100 XP_011536310 (OMIM: 601657) PREDICTED: epiphycan i ( 261) 764 149.4 6.8e-36 NP_004941 (OMIM: 601657) epiphycan precursor [Homo ( 322) 764 149.5 7.9e-36 NP_055174 (OMIM: 605127) opticin precursor [Homo s ( 332) 711 139.9 6.5e-33 XP_011507708 (OMIM: 605127) PREDICTED: opticin iso ( 332) 711 139.9 6.5e-33 NP_003053 (OMIM: 603745) slit homolog 3 protein is (1523) 269 60.1 3.1e-08 NP_001258875 (OMIM: 603745) slit homolog 3 protein (1530) 269 60.1 3.1e-08 NP_002336 (OMIM: 600616) lumican precursor [Homo s ( 338) 258 57.5 4.3e-08 XP_016874406 (OMIM: 125255,610048) PREDICTED: deco ( 359) 237 53.7 6.3e-07 NP_598010 (OMIM: 125255,610048) decorin isoform a ( 359) 237 53.7 6.3e-07 XP_006719333 (OMIM: 125255,610048) PREDICTED: deco ( 359) 237 53.7 6.3e-07 XP_005268750 (OMIM: 125255,610048) PREDICTED: deco ( 359) 237 53.7 6.3e-07 NP_001911 (OMIM: 125255,610048) decorin isoform a ( 359) 237 53.7 6.3e-07 NP_849161 (OMIM: 610867) leucine-rich repeat trans ( 522) 237 53.8 8.2e-07 XP_016859475 (OMIM: 610867) PREDICTED: leucine-ric ( 522) 237 53.8 8.2e-07 XP_016859476 (OMIM: 610867) PREDICTED: leucine-ric ( 522) 237 53.8 8.2e-07 NP_002716 (OMIM: 601914) prolargin precursor [Homo ( 382) 229 52.2 1.8e-06 NP_958505 (OMIM: 601914) prolargin precursor [Homo ( 382) 229 52.2 1.8e-06 NP_079269 (OMIM: 610870) leucine-rich repeat trans ( 518) 223 51.3 4.8e-06 NP_001269857 (OMIM: 610870) leucine-rich repeat tr ( 519) 223 51.3 4.8e-06 NP_001128217 (OMIM: 610870) leucine-rich repeat tr ( 590) 223 51.3 5.2e-06 NP_001269853 (OMIM: 610870) leucine-rich repeat tr ( 590) 223 51.3 5.2e-06 NP_001317299 (OMIM: 610870) leucine-rich repeat tr ( 591) 223 51.3 5.2e-06 NP_055632 (OMIM: 613356) TLR4 interactor with leuc ( 811) 224 51.7 5.8e-06 NP_003052 (OMIM: 603742) slit homolog 1 protein pr (1534) 220 51.2 1.5e-05 XP_016865268 (OMIM: 603745) PREDICTED: slit homolo (1460) 213 49.9 3.5e-05 NP_001333074 (OMIM: 604807) leucine-rich repeat tr ( 660) 195 46.3 0.00019 NP_001333073 (OMIM: 604807) leucine-rich repeat tr ( 660) 195 46.3 0.00019 NP_001333072 (OMIM: 604807) leucine-rich repeat tr ( 660) 195 46.3 0.00019 NP_037363 (OMIM: 604807) leucine-rich repeat trans ( 660) 195 46.3 0.00019 XP_016876624 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 195 46.3 0.00019 XP_011534913 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 195 46.3 0.00019 XP_016876623 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 195 46.3 0.00019 XP_016876620 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 195 46.3 0.00019 XP_016876619 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 195 46.3 0.00019 XP_016876618 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 195 46.3 0.00019 XP_005267547 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 195 46.3 0.00019 XP_016876622 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 195 46.3 0.00019 NP_001333075 (OMIM: 604807) leucine-rich repeat tr ( 660) 195 46.3 0.00019 XP_016876621 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 195 46.3 0.00019 NP_004479 (OMIM: 173511) platelet glycoprotein V p ( 560) 189 45.1 0.00037 NP_821079 (OMIM: 610869) leucine-rich repeat trans ( 581) 189 45.2 0.00038 NP_006329 (OMIM: 605492) leucine-rich repeat neuro ( 713) 187 44.9 0.00056 XP_005244884 (OMIM: 605492) PREDICTED: leucine-ric ( 713) 187 44.9 0.00056 NP_963924 (OMIM: 605492) leucine-rich repeat neuro ( 713) 187 44.9 0.00056 XP_011507368 (OMIM: 605492) PREDICTED: leucine-ric ( 713) 187 44.9 0.00056 XP_016855539 (OMIM: 605492) PREDICTED: leucine-ric ( 713) 187 44.9 0.00056 NP_001010847 (OMIM: 615212) leucine-rich repeat-co ( 294) 174 42.1 0.0016 >>NP_054776 (OMIM: 602383) mimecan isoform 2 precursor [ (298 aa) initn: 1946 init1: 1946 opt: 1946 Z-score: 1927.1 bits: 364.6 E(85289): 1.3e-100 Smith-Waterman score: 1946; 100.0% identity (100.0% similar) in 298 aa overlap (1-298:1-298) 10 20 30 40 50 60 pF1KE0 MKTLQSTLLLLLLVPLIKPAPPTQQDSRIIYDYGTDNFEESIFSQDYEDKYLDGKNIKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 MKTLQSTLLLLLLVPLIKPAPPTQQDSRIIYDYGTDNFEESIFSQDYEDKYLDGKNIKEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 ETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 SAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 KLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 KLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIH 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 LQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 LQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF 250 260 270 280 290 >>NP_148935 (OMIM: 602383) mimecan isoform 2 precursor [ (298 aa) initn: 1946 init1: 1946 opt: 1946 Z-score: 1927.1 bits: 364.6 E(85289): 1.3e-100 Smith-Waterman score: 1946; 100.0% identity (100.0% similar) in 298 aa overlap (1-298:1-298) 10 20 30 40 50 60 pF1KE0 MKTLQSTLLLLLLVPLIKPAPPTQQDSRIIYDYGTDNFEESIFSQDYEDKYLDGKNIKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_148 MKTLQSTLLLLLLVPLIKPAPPTQQDSRIIYDYGTDNFEESIFSQDYEDKYLDGKNIKEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_148 ETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_148 SAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 KLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_148 KLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIH 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 LQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_148 LQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF 250 260 270 280 290 >>NP_077727 (OMIM: 602383) mimecan isoform 1 [Homo sapie (356 aa) initn: 1933 init1: 1933 opt: 1933 Z-score: 1913.3 bits: 362.3 E(85289): 7.8e-100 Smith-Waterman score: 1933; 100.0% identity (100.0% similar) in 296 aa overlap (3-298:61-356) 10 20 30 pF1KE0 MKTLQSTLLLLLLVPLIKPAPPTQQDSRIIYD :::::::::::::::::::::::::::::: NP_077 FSHSPSHLGLMHRHEHLLRKTTKNFKTATTTLQSTLLLLLLVPLIKPAPPTQQDSRIIYD 40 50 60 70 80 90 40 50 60 70 80 90 pF1KE0 YGTDNFEESIFSQDYEDKYLDGKNIKEKETVIIPNEKSLQLQKDEAITPLPPKKENDEMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 YGTDNFEESIFSQDYEDKYLDGKNIKEKETVIIPNEKSLQLQKDEAITPLPPKKENDEMP 100 110 120 130 140 150 100 110 120 130 140 150 pF1KE0 TCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 TCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTG 160 170 180 190 200 210 160 170 180 190 200 210 pF1KE0 NLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 NLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKKL 220 230 240 250 260 270 220 230 240 250 260 270 pF1KE0 NNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 NNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRL 280 290 300 310 320 330 280 290 pF1KE0 EGNPIVLGKHPNSFICLKRLPIGSYF :::::::::::::::::::::::::: NP_077 EGNPIVLGKHPNSFICLKRLPIGSYF 340 350 >>XP_011536310 (OMIM: 601657) PREDICTED: epiphycan isofo (261 aa) initn: 760 init1: 760 opt: 764 Z-score: 765.3 bits: 149.4 E(85289): 6.8e-36 Smith-Waterman score: 764; 48.4% identity (78.9% similar) in 223 aa overlap (74-296:38-259) 50 60 70 80 90 100 pF1KE0 SQDYEDKYLDGKNIKEKETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGS :. : : :. :...::::::.:.: . XP_011 LLTPPPQPEKAQEEEEEEESTPRLIDGSSPQEPEFTGVLGPHT-NEDFPTCLLCTCISTT 10 20 30 40 50 60 110 120 130 140 150 160 pF1KE0 VYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTF :::.. ..::.:::::..::.:.:::.:::.. .:::.. .:.:.:.:.::: .:.. .: XP_011 VYCDDHELDAIPPLPKNTAYFYSRFNRIKKINKNDFASLSDLKRIDLTSNLISEIDEDAF 70 80 90 100 110 120 170 180 190 200 210 220 pF1KE0 SKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHN :: :.:: : .:.. .:: :: ::... . :.. .::: .::: . .: ::: : XP_011 RKLPQLRELVLRDNKIRQLPELPTTLTFIDISNNRLGRKGIKQEAFKDMYDLHHLYLTDN 130 140 150 160 170 180 230 240 250 260 270 280 pF1KE0 ALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHP :. .:: :::.::..::: ::: . .::::.... .::: .:.:::.:::: :.: : XP_011 NLDHIPLPLPENLRALHLQNNNILEMHEDTFCNVKNLTYIRKALEDIRLDGNPINLSKTP 190 200 210 220 230 240 290 pF1KE0 NSFICLKRLPIGSYF ....:: :::.:: XP_011 QAYMCLPRLPVGSLV 250 260 >>NP_004941 (OMIM: 601657) epiphycan precursor [Homo sap (322 aa) initn: 783 init1: 760 opt: 764 Z-score: 764.2 bits: 149.5 E(85289): 7.9e-36 Smith-Waterman score: 770; 39.7% identity (68.3% similar) in 325 aa overlap (1-296:1-320) 10 20 30 40 50 pF1KE0 MKTLQSTLLLLLLVPLIKPAPPTQQDSRIIYDYGTDNFEESIFSQD----YEDKYLDGKN :::: . .: :.. :: .. : :: ..... .. . : ::. .: . NP_004 MKTLAGLVLGLVIFDAAVTAPTLES---INYD--SETYDATLEDLDNLYNYENIPVDKVE 10 20 30 40 50 60 70 80 90 pF1KE0 IK--------EKETVIIPN--EKSLQLQKDEAITPL------PPKKE---------NDEM :. ..: . : ::. . ...: :: : . : :... NP_004 IEIATVMPSGNRELLTPPPQPEKAQEEEEEEESTPRLIDGSSPQEPEFTGVLGPHTNEDF 60 70 80 90 100 110 100 110 120 130 140 150 pF1KE0 PTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFT ::::::.:.: .:::.. ..::.:::::..::.:.:::.:::.. .:::.. .:.:.:.: NP_004 PTCLLCTCISTTVYCDDHELDAIPPLPKNTAYFYSRFNRIKKINKNDFASLSDLKRIDLT 120 130 140 150 160 170 160 170 180 190 200 210 pF1KE0 GNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKK .::: .:.. .: :: :.:: : .:.. .:: :: ::... . :.. .::: .::: NP_004 SNLISEIDEDAFRKLPQLRELVLRDNKIRQLPELPTTLTFIDISNNRLGRKGIKQEAFKD 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE0 LNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIR . .: ::: : :. .:: :::.::..::: ::: . .::::.... .::: .:.:: NP_004 MYDLHHLYLTDNNLDHIPLPLPENLRALHLQNNNILEMHEDTFCNVKNLTYIRKALEDIR 240 250 260 270 280 290 280 290 pF1KE0 LEGNPIVLGKHPNSFICLKRLPIGSYF :.:::: :.: :....:: :::.:: NP_004 LDGNPINLSKTPQAYMCLPRLPVGSLV 300 310 320 >>NP_055174 (OMIM: 605127) opticin precursor [Homo sapie (332 aa) initn: 753 init1: 704 opt: 711 Z-score: 711.9 bits: 139.9 E(85289): 6.5e-33 Smith-Waterman score: 711; 45.8% identity (77.4% similar) in 212 aa overlap (86-297:120-331) 60 70 80 90 100 110 pF1KE0 NIKEKETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVP . : .::::.::::..::::...:.. .: NP_055 SPAKSTTAPGTPSSNPTMTRPTTAGLLLSSQPNHGLPTCLVCVCLGSSVYCDDIDLEDIP 90 100 110 120 130 140 120 130 140 150 160 170 pF1KE0 PLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLA :::...::::::::.:... :.:: . .:.:.:...::: .:.. .: : :..: : NP_055 PLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILP 150 160 170 180 190 200 180 190 200 210 220 230 pF1KE0 ENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPES :::: ::::: . ..... :...: ::. ::. ...: ::::. : :.:.: :: : NP_055 ENQLEALPVLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLS 210 220 230 240 250 260 240 250 260 270 280 290 pF1KE0 LRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIG :: .::: : : .. :.:: .. .. : ..:.:::.:::: :. :....:: ::::: NP_055 LRSVHLQNNLIETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIG 270 280 290 300 310 320 pF1KE0 SYF . NP_055 RFT 330 >>XP_011507708 (OMIM: 605127) PREDICTED: opticin isoform (332 aa) initn: 753 init1: 704 opt: 711 Z-score: 711.9 bits: 139.9 E(85289): 6.5e-33 Smith-Waterman score: 711; 45.8% identity (77.4% similar) in 212 aa overlap (86-297:120-331) 60 70 80 90 100 110 pF1KE0 NIKEKETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVP . : .::::.::::..::::...:.. .: XP_011 SPAKSTTAPGTPSSNPTMTRPTTAGLLLSSQPNHGLPTCLVCVCLGSSVYCDDIDLEDIP 90 100 110 120 130 140 120 130 140 150 160 170 pF1KE0 PLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLA :::...::::::::.:... :.:: . .:.:.:...::: .:.. .: : :..: : XP_011 PLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILP 150 160 170 180 190 200 180 190 200 210 220 230 pF1KE0 ENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPES :::: ::::: . ..... :...: ::. ::. ...: ::::. : :.:.: :: : XP_011 ENQLEALPVLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLS 210 220 230 240 250 260 240 250 260 270 280 290 pF1KE0 LRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIG :: .::: : : .. :.:: .. .. : ..:.:::.:::: :. :....:: ::::: XP_011 LRSVHLQNNLIETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIG 270 280 290 300 310 320 pF1KE0 SYF . XP_011 RFT 330 >>NP_003053 (OMIM: 603745) slit homolog 3 protein isofor (1523 aa) initn: 162 init1: 117 opt: 269 Z-score: 268.9 bits: 60.1 E(85289): 3.1e-08 Smith-Waterman score: 269; 33.0% identity (57.7% similar) in 194 aa overlap (97-282:38-222) 70 80 90 100 110 120 pF1KE0 NEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVP-PLPKESAYLY :.: ..:: :. . . ::: .:... : NP_003 VGAAVRARLALALALASVLSGPPAVACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLD 10 20 30 40 50 60 130 140 150 160 170 180 pF1KE0 ARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVL :.: ..: ::: . ::: : . : . :: :.:. :. ::.: : .:.: :: : NP_003 LDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPEL 70 80 90 100 110 120 190 200 210 220 230 pF1KE0 ----PPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLR---V :::: .. . :.:. :: .::. .... : ::.: . . . ..:: . NP_003 LFQSTPKLTRLDLSENQIQ--GIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEI 130 140 150 160 170 180 240 250 260 270 280 290 pF1KE0 IHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF . :. :::. : .: : :: .::..: . : NP_003 LTLNNNNISRILVTSF---NHMPKIRT----LRLHSNHLYCDCHLAWLSDWLRQRRTVGQ 190 200 210 220 230 NP_003 FTLCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSCNANSISCPSPCTCSNNIVDCRGKGL 240 250 260 270 280 290 >>NP_001258875 (OMIM: 603745) slit homolog 3 protein iso (1530 aa) initn: 162 init1: 117 opt: 269 Z-score: 268.9 bits: 60.1 E(85289): 3.1e-08 Smith-Waterman score: 269; 33.0% identity (57.7% similar) in 194 aa overlap (97-282:38-222) 70 80 90 100 110 120 pF1KE0 NEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVP-PLPKESAYLY :.: ..:: :. . . ::: .:... : NP_001 VGAAVRARLALALALASVLSGPPAVACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLD 10 20 30 40 50 60 130 140 150 160 170 180 pF1KE0 ARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVL :.: ..: ::: . ::: : . : . :: :.:. :. ::.: : .:.: :: : NP_001 LDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPEL 70 80 90 100 110 120 190 200 210 220 230 pF1KE0 ----PPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLR---V :::: .. . :.:. :: .::. .... : ::.: . . . ..:: . NP_001 LFQSTPKLTRLDLSENQIQ--GIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEI 130 140 150 160 170 180 240 250 260 270 280 290 pF1KE0 IHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF . :. :::. : .: : :: .::..: . : NP_001 LTLNNNNISRILVTSF---NHMPKIRT----LRLHSNHLYCDCHLAWLSDWLRQRRTVGQ 190 200 210 220 230 NP_001 FTLCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSCNANSISCPSPCTCSNNIVDCRGKGL 240 250 260 270 280 290 >>NP_002336 (OMIM: 600616) lumican precursor [Homo sapie (338 aa) initn: 261 init1: 123 opt: 258 Z-score: 266.3 bits: 57.5 E(85289): 4.3e-08 Smith-Waterman score: 278; 30.4% identity (58.4% similar) in 214 aa overlap (92-276:35-247) 70 80 90 100 110 pF1KE0 TVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCL-LCVC---LSGSVYCEEVDIDAVPPL :.: : : ...::.:. . .:: . NP_002 AFTLFLALIGGTSGQYYDYDFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMV 10 20 30 40 50 60 120 130 140 150 160 pF1KE0 PKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIED--IEDGTFSKLSLL------ : ::: : :.: .. : : .. .:. : . ::.:. :. .::::. : NP_002 PPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHIN 70 80 90 100 110 120 170 180 190 200 210 pF1KE0 ---------------EELSLAENQLLKLPVLPP--KLTLFNAKYNKIKSRGIKANAFKKL :.:.:..:.. :: . .::... ..:..: ...: ::: : NP_002 HNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSA-AFKGL 130 140 150 160 170 180 220 230 240 250 260 270 pF1KE0 NNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRL ..: .: :. : . .: .:: :: ...:. :.:..: :. : . : .:.: .:. NP_002 KSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELAD 190 200 210 220 230 240 280 290 pF1KE0 EGNPIVLGKHPNSFICLKRLPIGSYF : : NP_002 SGIPGNSFNVSSLVELDLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGPLSY 250 260 270 280 290 300 298 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:11:19 2016 done: Thu Nov 3 12:11:21 2016 Total Scan time: 7.550 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]