FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0407, 254 aa
  1>>>pF1KE0407 254 - 254 aa - 254 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.1857+/-0.000573; mu= 1.0857+/- 0.035
 mean_var=157.4751+/-32.098, 0's: 0 Z-trim(110.6): 44  B-trim: 808 in 1/53
 Lambda= 0.102204
 statistics sampled from 18986 (19009) to 18986 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.577), E-opt: 0.2 (0.223), width:  16
 Scan time:  6.560

The best scores are:                                      opt bits E(85289)
NP_001026883 (OMIM: 616952) mitochondrial calcium  ( 359)  761 124.4 2.7e-28
XP_011513104 (OMIM: 616952) PREDICTED: mitochondri ( 351)  660 109.5 8.1e-24


>>NP_001026883 (OMIM: 616952) mitochondrial calcium unip  (359 aa)
 initn: 820 init1: 747 opt: 761  Z-score: 628.9  bits: 124.4 E(85289): 2.7e-28
Smith-Waterman score: 761; 49.2% identity (77.0% similar) in 252 aa overlap (6-253:109-358)

                                        10        20         30    
pF1KE0                          MNSRQAWRLFLSQGRGDRWVSRPRGHF-SPAL---
                                     :::   : : .    . :. :  .:::   
NP_001 RLAAAAPRRQLGDWERSRLGYAAPPAGRSSAWR--CSPGVAAAAGALPQYHGPAPALVSC
       80        90       100       110         120       130      

              40        50        60        70        80        90 
pF1KE0 RREFFTTTTKEGYDRRPVDITPLEQRKLTFDTHALVQDLETHGFDKTQAETIVSALTALS
       :::.  .. .   .:.  :.:   .::: :::::::  :: .::   ::: :::::. . 
NP_001 RRELSLSAGSLQLERKRRDFTSSGSRKLYFDTHALVCLLEDNGFATQQAEIIVSALVKIL
        140       150       160       170       180       190      

             100       110       120       130       140       150 
pF1KE0 NVSLDTIYKEMVTQAQQEITVQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQV
       ....: .::.:::. ::::: ::.:...  ..:::.:::::::. :::::::.:.:: :.
NP_001 EANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSEFSALRAENEKIKLELHQL
        200       210       220       230       240       250      

             160       170       180       190       200       210 
pF1KE0 KQQLMHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSN
       :::.: :. ..:.:.:::.:::.::: .... .::.:.:  ::..   .:    ...:. 
NP_001 KQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRALTQTDR
        260       270       280       290       300       310      

             220       230       240       250    
pF1KE0 KIDAEIASLKTLMESNKLETIRYLAASVFTCLAIALGFYRFWK
       ::..:.:.:::..::.::..:.:::.:.::::..::::::.: 
NP_001 KIETEVAGLKTMLESHKLDNIKYLAGSIFTCLTVALGFYRLWI
        320       330       340       350         

>>XP_011513104 (OMIM: 616952) PREDICTED: mitochondrial c  (351 aa)
 initn: 646 init1: 646 opt: 660  Z-score: 548.6  bits: 109.5 E(85289): 8.1e-24
Smith-Waterman score: 660; 47.7% identity (75.3% similar) in 235 aa overlap (6-236:109-341)

                                        10        20         30    
pF1KE0                          MNSRQAWRLFLSQGRGDRWVSRPRGHF-SPAL---
                                     :::   : : .    . :. :  .:::   
XP_011 RLAAAAPRRQLGDWERSRLGYAAPPAGRSSAWR--CSPGVAAAAGALPQYHGPAPALVSC
       80        90       100       110         120       130      

              40        50        60        70        80        90 
pF1KE0 RREFFTTTTKEGYDRRPVDITPLEQRKLTFDTHALVQDLETHGFDKTQAETIVSALTALS
       :::.  .. .   .:.  :.:   .::: :::::::  :: .::   ::: :::::. . 
XP_011 RRELSLSAGSLQLERKRRDFTSSGSRKLYFDTHALVCLLEDNGFATQQAEIIVSALVKIL
        140       150       160       170       180       190      

             100       110       120       130       140       150 
pF1KE0 NVSLDTIYKEMVTQAQQEITVQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQV
       ....: .::.:::. ::::: ::.:...  ..:::.:::::::. :::::::.:.:: :.
XP_011 EANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSEFSALRAENEKIKLELHQL
        200       210       220       230       240       250      

             160       170       180       190       200       210 
pF1KE0 KQQLMHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSN
       :::.: :. ..:.:.:::.:::.::: .... .::.:.:  ::..   .:    ...:. 
XP_011 KQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRALTQTDR
        260       270       280       290       300       310      

             220       230       240       250    
pF1KE0 KIDAEIASLKTLMESNKLETIRYLAASVFTCLAIALGFYRFWK
       ::..:.:.:::..::.::..:.:::                  
XP_011 KIETEVAGLKTMLESHKLDNIKYLAERSPQKRQHT        
        320       330       340       350         




254 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 12:03:05 2016 done: Thu Nov  3 12:03:06 2016
 Total Scan time:  6.560 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]