FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0408, 329 aa
1>>>pF1KE0408 329 - 329 aa - 329 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5224+/-0.000291; mu= 11.9772+/- 0.019
mean_var=114.2471+/-22.855, 0's: 0 Z-trim(121.2): 6 B-trim: 278 in 1/49
Lambda= 0.119992
statistics sampled from 37454 (37461) to 37454 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.773), E-opt: 0.2 (0.439), width: 16
Scan time: 8.110
The best scores are: opt bits E(85289)
NP_001275685 (OMIM: 612766) BRISC and BRCA1-A comp ( 329) 2204 391.7 1.2e-108
NP_054892 (OMIM: 612766) BRISC and BRCA1-A complex ( 329) 2204 391.7 1.2e-108
NP_001028721 (OMIM: 612766) BRISC and BRCA1-A comp ( 329) 2204 391.7 1.2e-108
NP_001275686 (OMIM: 612766) BRISC and BRCA1-A comp ( 254) 953 175.0 1.5e-43
>>NP_001275685 (OMIM: 612766) BRISC and BRCA1-A complex (329 aa)
initn: 2204 init1: 2204 opt: 2204 Z-score: 2071.8 bits: 391.7 E(85289): 1.2e-108
Smith-Waterman score: 2204; 100.0% identity (100.0% similar) in 329 aa overlap (1-329:1-329)
10 20 30 40 50 60
pF1KE0 MEVAEPSSPTEEEEEEEEHSAEPRPRTRSNPEGAEDRAVGAQASVGSRSEGEGEAASADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEVAEPSSPTEEEEEEEEHSAEPRPRTRSNPEGAEDRAVGAQASVGSRSEGEGEAASADD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GSLNTSGAGPKSWQVPPPAPEVQIRTPRVNCPEKVIICLDLSEEMSLPKLESFNGSKTNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSLNTSGAGPKSWQVPPPAPEVQIRTPRVNCPEKVIICLDLSEEMSLPKLESFNGSKTNA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LNVSQKMIEMFVRTKHKIDKSHEFALVVVNDDTAWLSGLTSDPRELCSCLYDLETASCST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNVSQKMIEMFVRTKHKIDKSHEFALVVVNDDTAWLSGLTSDPRELCSCLYDLETASCST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 FNLEGLFSLIQQKTELPVTENVQTIPPPYVVRTILVYSRPPCQPQFSLTEPMKKMFQCPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNLEGLFSLIQQKTELPVTENVQTIPPPYVVRTILVYSRPPCQPQFSLTEPMKKMFQCPY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 FFFDVVYIHNGTEEKEEEMSWKDMFAFMGSLDTKGTSYKYEVALAGPALELHNCMAKLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFFDVVYIHNGTEEKEEEMSWKDMFAFMGSLDTKGTSYKYEVALAGPALELHNCMAKLLA
250 260 270 280 290 300
310 320
pF1KE0 HPLQRPCQSHASYSLLEEEDEAIEVEATV
:::::::::::::::::::::::::::::
NP_001 HPLQRPCQSHASYSLLEEEDEAIEVEATV
310 320
>>NP_054892 (OMIM: 612766) BRISC and BRCA1-A complex mem (329 aa)
initn: 2204 init1: 2204 opt: 2204 Z-score: 2071.8 bits: 391.7 E(85289): 1.2e-108
Smith-Waterman score: 2204; 100.0% identity (100.0% similar) in 329 aa overlap (1-329:1-329)
10 20 30 40 50 60
pF1KE0 MEVAEPSSPTEEEEEEEEHSAEPRPRTRSNPEGAEDRAVGAQASVGSRSEGEGEAASADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MEVAEPSSPTEEEEEEEEHSAEPRPRTRSNPEGAEDRAVGAQASVGSRSEGEGEAASADD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GSLNTSGAGPKSWQVPPPAPEVQIRTPRVNCPEKVIICLDLSEEMSLPKLESFNGSKTNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 GSLNTSGAGPKSWQVPPPAPEVQIRTPRVNCPEKVIICLDLSEEMSLPKLESFNGSKTNA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LNVSQKMIEMFVRTKHKIDKSHEFALVVVNDDTAWLSGLTSDPRELCSCLYDLETASCST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 LNVSQKMIEMFVRTKHKIDKSHEFALVVVNDDTAWLSGLTSDPRELCSCLYDLETASCST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 FNLEGLFSLIQQKTELPVTENVQTIPPPYVVRTILVYSRPPCQPQFSLTEPMKKMFQCPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 FNLEGLFSLIQQKTELPVTENVQTIPPPYVVRTILVYSRPPCQPQFSLTEPMKKMFQCPY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 FFFDVVYIHNGTEEKEEEMSWKDMFAFMGSLDTKGTSYKYEVALAGPALELHNCMAKLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 FFFDVVYIHNGTEEKEEEMSWKDMFAFMGSLDTKGTSYKYEVALAGPALELHNCMAKLLA
250 260 270 280 290 300
310 320
pF1KE0 HPLQRPCQSHASYSLLEEEDEAIEVEATV
:::::::::::::::::::::::::::::
NP_054 HPLQRPCQSHASYSLLEEEDEAIEVEATV
310 320
>>NP_001028721 (OMIM: 612766) BRISC and BRCA1-A complex (329 aa)
initn: 2204 init1: 2204 opt: 2204 Z-score: 2071.8 bits: 391.7 E(85289): 1.2e-108
Smith-Waterman score: 2204; 100.0% identity (100.0% similar) in 329 aa overlap (1-329:1-329)
10 20 30 40 50 60
pF1KE0 MEVAEPSSPTEEEEEEEEHSAEPRPRTRSNPEGAEDRAVGAQASVGSRSEGEGEAASADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEVAEPSSPTEEEEEEEEHSAEPRPRTRSNPEGAEDRAVGAQASVGSRSEGEGEAASADD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GSLNTSGAGPKSWQVPPPAPEVQIRTPRVNCPEKVIICLDLSEEMSLPKLESFNGSKTNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSLNTSGAGPKSWQVPPPAPEVQIRTPRVNCPEKVIICLDLSEEMSLPKLESFNGSKTNA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LNVSQKMIEMFVRTKHKIDKSHEFALVVVNDDTAWLSGLTSDPRELCSCLYDLETASCST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNVSQKMIEMFVRTKHKIDKSHEFALVVVNDDTAWLSGLTSDPRELCSCLYDLETASCST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 FNLEGLFSLIQQKTELPVTENVQTIPPPYVVRTILVYSRPPCQPQFSLTEPMKKMFQCPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNLEGLFSLIQQKTELPVTENVQTIPPPYVVRTILVYSRPPCQPQFSLTEPMKKMFQCPY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 FFFDVVYIHNGTEEKEEEMSWKDMFAFMGSLDTKGTSYKYEVALAGPALELHNCMAKLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFFDVVYIHNGTEEKEEEMSWKDMFAFMGSLDTKGTSYKYEVALAGPALELHNCMAKLLA
250 260 270 280 290 300
310 320
pF1KE0 HPLQRPCQSHASYSLLEEEDEAIEVEATV
:::::::::::::::::::::::::::::
NP_001 HPLQRPCQSHASYSLLEEEDEAIEVEATV
310 320
>>NP_001275686 (OMIM: 612766) BRISC and BRCA1-A complex (254 aa)
initn: 1087 init1: 947 opt: 953 Z-score: 903.0 bits: 175.0 E(85289): 1.5e-43
Smith-Waterman score: 1556; 77.2% identity (77.2% similar) in 329 aa overlap (1-329:1-254)
10 20 30 40 50 60
pF1KE0 MEVAEPSSPTEEEEEEEEHSAEPRPRTRSNPEGAEDRAVGAQASVGSRSEGEGEAASADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEVAEPSSPTEEEEEEEEHSAEPRPRTRSNPEGAEDRAVGAQASVGSRSEGEGEAASADD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GSLNTSGAGPKSWQVPPPAPEVQIRTPRVNCPEKVIICLDLSEEMSLPKLESFNGSKTNA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSLNTSGAGPKSWQVPPPAPEVQIRTPRVNCPEKVIICLDLSEEMSLPKLESFNG-----
70 80 90 100 110
130 140 150 160 170 180
pF1KE0 LNVSQKMIEMFVRTKHKIDKSHEFALVVVNDDTAWLSGLTSDPRELCSCLYDLETASCST
NP_001 ------------------------------------------------------------
190 200 210 220 230 240
pF1KE0 FNLEGLFSLIQQKTELPVTENVQTIPPPYVVRTILVYSRPPCQPQFSLTEPMKKMFQCPY
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----------QQKTELPVTENVQTIPPPYVVRTILVYSRPPCQPQFSLTEPMKKMFQCPY
120 130 140 150 160
250 260 270 280 290 300
pF1KE0 FFFDVVYIHNGTEEKEEEMSWKDMFAFMGSLDTKGTSYKYEVALAGPALELHNCMAKLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFFDVVYIHNGTEEKEEEMSWKDMFAFMGSLDTKGTSYKYEVALAGPALELHNCMAKLLA
170 180 190 200 210 220
310 320
pF1KE0 HPLQRPCQSHASYSLLEEEDEAIEVEATV
:::::::::::::::::::::::::::::
NP_001 HPLQRPCQSHASYSLLEEEDEAIEVEATV
230 240 250
329 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 11:57:40 2016 done: Thu Nov 3 11:57:41 2016
Total Scan time: 8.110 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]