FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0409, 195 aa 1>>>pF1KE0409 195 - 195 aa - 195 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2449+/-0.000362; mu= 13.1192+/- 0.022 mean_var=59.4779+/-11.753, 0's: 0 Z-trim(112.6): 14 B-trim: 727 in 1/55 Lambda= 0.166302 statistics sampled from 21535 (21545) to 21535 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.651), E-opt: 0.2 (0.253), width: 16 Scan time: 5.530 The best scores are: opt bits E(85289) NP_001121614 (OMIM: 615875) RWD domain-containing ( 195) 1282 315.8 2.7e-86 NP_056300 (OMIM: 615875) RWD domain-containing pro ( 267) 1256 309.7 2.7e-84 NP_001186611 (OMIM: 615875) RWD domain-containing ( 200) 1165 287.8 7.9e-78 NP_001265177 (OMIM: 615875) RWD domain-containing ( 252) 1067 264.3 1.2e-70 NP_001265176 (OMIM: 615875) RWD domain-containing ( 185) 976 242.4 3.3e-64 >>NP_001121614 (OMIM: 615875) RWD domain-containing prot (195 aa) initn: 1282 init1: 1282 opt: 1282 Z-score: 1670.2 bits: 315.8 E(85289): 2.7e-86 Smith-Waterman score: 1282; 99.5% identity (100.0% similar) in 195 aa overlap (1-195:1-195) 10 20 30 40 50 60 pF1KE0 MAEPVQEELSVLAAIFCRPHEWEVLSRSETDGTVFRIHTKAEGFMDADIPLELVFHLPVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAEPVQEELSVLAAIFCRPHEWEVLSRSETDGTVFRIHTKAEGFMDADIPLELVFHLPVN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 YPSCLPGISINSEQLTRAQCVTVKEKLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: NP_001 YPSCLPGISINSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGKIIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGKIIL 130 140 150 160 170 180 190 pF1KE0 ILLQGDRNNLKVPKS ::::::::::::::: NP_001 ILLQGDRNNLKVPKS 190 >>NP_056300 (OMIM: 615875) RWD domain-containing protein (267 aa) initn: 1256 init1: 1256 opt: 1256 Z-score: 1634.3 bits: 309.7 E(85289): 2.7e-84 Smith-Waterman score: 1256; 99.5% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KE0 MAEPVQEELSVLAAIFCRPHEWEVLSRSETDGTVFRIHTKAEGFMDADIPLELVFHLPVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MAEPVQEELSVLAAIFCRPHEWEVLSRSETDGTVFRIHTKAEGFMDADIPLELVFHLPVN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 YPSCLPGISINSEQLTRAQCVTVKEKLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: NP_056 YPSCLPGISINSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGKIIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGKIIL 130 140 150 160 170 180 190 pF1KE0 ILLQGDRNNLKVPKS ::::::::::: NP_056 ILLQGDRNNLKEYLILQKTSKVDVDSSGKKCKEKMISVLFETKVQTEHKRFLAFEVKEYS 190 200 210 220 230 240 >>NP_001186611 (OMIM: 615875) RWD domain-containing prot (200 aa) initn: 1165 init1: 1165 opt: 1165 Z-score: 1518.3 bits: 287.8 E(85289): 7.9e-78 Smith-Waterman score: 1165; 99.4% identity (100.0% similar) in 176 aa overlap (1-176:1-176) 10 20 30 40 50 60 pF1KE0 MAEPVQEELSVLAAIFCRPHEWEVLSRSETDGTVFRIHTKAEGFMDADIPLELVFHLPVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAEPVQEELSVLAAIFCRPHEWEVLSRSETDGTVFRIHTKAEGFMDADIPLELVFHLPVN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 YPSCLPGISINSEQLTRAQCVTVKEKLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: NP_001 YPSCLPGISINSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGKIIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGVLDS 130 140 150 160 170 180 190 pF1KE0 ILLQGDRNNLKVPKS NP_001 SENLQSRCGLKWKEMQREND 190 200 >>NP_001265177 (OMIM: 615875) RWD domain-containing prot (252 aa) initn: 1067 init1: 1067 opt: 1067 Z-score: 1389.6 bits: 264.3 E(85289): 1.2e-70 Smith-Waterman score: 1067; 99.4% identity (100.0% similar) in 163 aa overlap (29-191:14-176) 10 20 30 40 50 60 pF1KE0 MAEPVQEELSVLAAIFCRPHEWEVLSRSETDGTVFRIHTKAEGFMDADIPLELVFHLPVN :::::::::::::::::::::::::::::::: NP_001 MFLSCGSLHQRGPETDGTVFRIHTKAEGFMDADIPLELVFHLPVN 10 20 30 40 70 80 90 100 110 120 pF1KE0 YPSCLPGISINSEQLTRAQCVTVKEKLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: NP_001 YPSCLPGISINSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGKIIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGKIIL 110 120 130 140 150 160 190 pF1KE0 ILLQGDRNNLKVPKS ::::::::::: NP_001 ILLQGDRNNLKEYLILQKTSKVDVDSSGKKCKEKMISVLFETKVQTEHKRFLAFEVKEYS 170 180 190 200 210 220 >>NP_001265176 (OMIM: 615875) RWD domain-containing prot (185 aa) initn: 976 init1: 976 opt: 976 Z-score: 1273.7 bits: 242.4 E(85289): 3.3e-64 Smith-Waterman score: 976; 99.3% identity (100.0% similar) in 148 aa overlap (29-176:14-161) 10 20 30 40 50 60 pF1KE0 MAEPVQEELSVLAAIFCRPHEWEVLSRSETDGTVFRIHTKAEGFMDADIPLELVFHLPVN :::::::::::::::::::::::::::::::: NP_001 MFLSCGSLHQRGPETDGTVFRIHTKAEGFMDADIPLELVFHLPVN 10 20 30 40 70 80 90 100 110 120 pF1KE0 YPSCLPGISINSEQLTRAQCVTVKEKLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: NP_001 YPSCLPGISINSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGKIIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGVLDS 110 120 130 140 150 160 190 pF1KE0 ILLQGDRNNLKVPKS NP_001 SENLQSRCGLKWKEMQREND 170 180 195 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 11:53:17 2016 done: Thu Nov 3 11:53:17 2016 Total Scan time: 5.530 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]