FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0414, 186 aa 1>>>pF1KE0414 186 - 186 aa - 186 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2144+/-0.000319; mu= 13.0684+/- 0.020 mean_var=57.2536+/-11.162, 0's: 0 Z-trim(115.1): 26 B-trim: 22 in 1/56 Lambda= 0.169501 statistics sampled from 25319 (25345) to 25319 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.297), width: 16 Scan time: 6.070 The best scores are: opt bits E(85289) NP_115637 (OMIM: 612412) speriolin-like protein is ( 186) 1215 304.9 4.8e-83 XP_005261245 (OMIM: 612412) PREDICTED: speriolin-l ( 340) 1215 305.0 8.2e-83 XP_016883969 (OMIM: 612412) PREDICTED: speriolin-l ( 340) 1215 305.0 8.2e-83 NP_001136326 (OMIM: 612412) speriolin-like protein ( 340) 1215 305.0 8.2e-83 XP_011528058 (OMIM: 612412) PREDICTED: speriolin-l ( 226) 1041 262.4 3.7e-70 NP_940974 (OMIM: 610874) speriolin isoform 1 [Homo ( 591) 515 133.9 4.5e-31 XP_011515324 (OMIM: 610874) PREDICTED: speriolin i ( 620) 322 86.7 7.6e-17 XP_011515323 (OMIM: 610874) PREDICTED: speriolin i ( 626) 322 86.7 7.6e-17 XP_011515326 (OMIM: 610874) PREDICTED: speriolin i ( 535) 208 58.8 1.6e-08 XP_016868888 (OMIM: 610874) PREDICTED: speriolin i ( 535) 208 58.8 1.6e-08 XP_011515327 (OMIM: 610874) PREDICTED: speriolin i ( 535) 208 58.8 1.6e-08 XP_011515325 (OMIM: 610874) PREDICTED: speriolin i ( 564) 208 58.9 1.7e-08 >>NP_115637 (OMIM: 612412) speriolin-like protein isofor (186 aa) initn: 1215 init1: 1215 opt: 1215 Z-score: 1611.9 bits: 304.9 E(85289): 4.8e-83 Smith-Waterman score: 1215; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186) 10 20 30 40 50 60 pF1KE0 MVRPKKVCFSESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 MVRPKKVCFSESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 VTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDSLLLLNCLCELSKEDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 SEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDSLLLLNCLCELSKEDG 130 140 150 160 170 180 pF1KE0 KPLFAW :::::: NP_115 KPLFAW >>XP_005261245 (OMIM: 612412) PREDICTED: speriolin-like (340 aa) initn: 1215 init1: 1215 opt: 1215 Z-score: 1607.8 bits: 305.0 E(85289): 8.2e-83 Smith-Waterman score: 1215; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:155-340) 10 20 30 pF1KE0 MVRPKKVCFSESSLPTGDRTRRSYYLNEIQ :::::::::::::::::::::::::::::: XP_005 SHRGTDRKLSPLLSPLQDSLVDKTLLEPREMVRPKKVCFSESSLPTGDRTRRSYYLNEIQ 130 140 150 160 170 180 40 50 60 70 80 90 pF1KE0 SFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDE 190 200 210 220 230 240 100 110 120 130 140 150 pF1KE0 RKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAALR 250 260 270 280 290 300 160 170 180 pF1KE0 KLVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLFAW :::::::::::::::::::::::::::::::::::: XP_005 KLVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLFAW 310 320 330 340 >>XP_016883969 (OMIM: 612412) PREDICTED: speriolin-like (340 aa) initn: 1215 init1: 1215 opt: 1215 Z-score: 1607.8 bits: 305.0 E(85289): 8.2e-83 Smith-Waterman score: 1215; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:155-340) 10 20 30 pF1KE0 MVRPKKVCFSESSLPTGDRTRRSYYLNEIQ :::::::::::::::::::::::::::::: XP_016 SHRGTDRKLSPLLSPLQDSLVDKTLLEPREMVRPKKVCFSESSLPTGDRTRRSYYLNEIQ 130 140 150 160 170 180 40 50 60 70 80 90 pF1KE0 SFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDE 190 200 210 220 230 240 100 110 120 130 140 150 pF1KE0 RKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAALR 250 260 270 280 290 300 160 170 180 pF1KE0 KLVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLFAW :::::::::::::::::::::::::::::::::::: XP_016 KLVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLFAW 310 320 330 340 >>NP_001136326 (OMIM: 612412) speriolin-like protein iso (340 aa) initn: 1215 init1: 1215 opt: 1215 Z-score: 1607.8 bits: 305.0 E(85289): 8.2e-83 Smith-Waterman score: 1215; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:155-340) 10 20 30 pF1KE0 MVRPKKVCFSESSLPTGDRTRRSYYLNEIQ :::::::::::::::::::::::::::::: NP_001 SHRGTDRKLSPLLSPLQDSLVDKTLLEPREMVRPKKVCFSESSLPTGDRTRRSYYLNEIQ 130 140 150 160 170 180 40 50 60 70 80 90 pF1KE0 SFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDE 190 200 210 220 230 240 100 110 120 130 140 150 pF1KE0 RKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAALR 250 260 270 280 290 300 160 170 180 pF1KE0 KLVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLFAW :::::::::::::::::::::::::::::::::::: NP_001 KLVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLFAW 310 320 330 340 >>XP_011528058 (OMIM: 612412) PREDICTED: speriolin-like (226 aa) initn: 1037 init1: 1037 opt: 1041 Z-score: 1380.6 bits: 262.4 E(85289): 3.7e-70 Smith-Waterman score: 1041; 95.3% identity (97.1% similar) in 171 aa overlap (16-186:57-226) 10 20 30 40 pF1KE0 MVRPKKVCFSESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEI :::.. :.:::::::::::::::::: XP_011 LTGGDPSQLRPPGPGSSVLAGADAGADSRVTGDQSP-PPRLKEIQSFAGAEKDARVVGEI 30 40 50 60 70 80 50 60 70 80 90 100 pF1KE0 AFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSA 90 100 110 120 130 140 110 120 130 140 150 160 pF1KE0 RLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDS 150 160 170 180 190 200 170 180 pF1KE0 LLLLNCLCELSKEDGKPLFAW ::::::::::::::::::::: XP_011 LLLLNCLCELSKEDGKPLFAW 210 220 >>NP_940974 (OMIM: 610874) speriolin isoform 1 [Homo sap (591 aa) initn: 477 init1: 386 opt: 515 Z-score: 678.8 bits: 133.9 E(85289): 4.5e-31 Smith-Waterman score: 515; 52.7% identity (82.7% similar) in 150 aa overlap (40-186:444-591) 10 20 30 40 50 60 pF1KE0 SESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTV :.:::::::::::::. .:: .::::::: NP_940 SMMEVERKLAHRKTSKFPENPRESKQLAWERLVGEIAFQLDRRILSSIFPERVRLYGFTV 420 430 440 450 460 470 70 80 90 100 110 120 pF1KE0 ANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYG .:::::: :.: . : ..::. ..:::::... ::..:::. ::::..: :.:.:: NP_940 SNIPEKIIQASLNPSDHKLDEKLCQRLTQRYVSVMNRLQSLGYNGRVHPALTEQLVNAYG 480 490 500 510 520 530 130 140 150 160 170 180 pF1KE0 ILKQRPDLRANPLHSSPAA---LRKLVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLFAW ::..::.: :. ...: . :...:...: : .:.:.::::.:: .:...::::.: : NP_940 ILRERPELAAS--EGGPYTVDFLQRVVVETVHPGMLADALLLLSCLSQLAHDDGKPMFIW 540 550 560 570 580 590 >>XP_011515324 (OMIM: 610874) PREDICTED: speriolin isofo (620 aa) initn: 463 init1: 193 opt: 322 Z-score: 423.4 bits: 86.7 E(85289): 7.6e-17 Smith-Waterman score: 439; 43.8% identity (67.6% similar) in 185 aa overlap (40-186:438-620) 10 20 30 40 50 60 pF1KE0 SESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTV :.:::::::::::::. .:: .::::::: XP_011 SMMEVERKLAHRKTSKFPENPRESKQLAWERLVGEIAFQLDRRILSSIFPERVRLYGFTV 410 420 430 440 450 460 70 80 90 pF1KE0 ANIPEKIEQTSTK-------SLDGS----------------------------VDERKLR .:::::: : . ::.:: .::. . XP_011 SNIPEKIIQLCLSVDCRPVCSLSGSYCELRGSRLELCLWLKHPWASLNPSDHKLDEKLCQ 470 480 490 500 510 520 100 110 120 130 140 150 pF1KE0 ELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAA---LRK .:::::... ::..:::. ::::..: :.:.::::..::.: :. ...: . :.. XP_011 RLTQRYVSVMNRLQSLGYNGRVHPALTEQLVNAYGILRERPELAAS--EGGPYTVDFLQR 530 540 550 560 570 580 160 170 180 pF1KE0 LVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLFAW .:...: : .:.:.::::.:: .:...::::.: : XP_011 VVVETVHPGMLADALLLLSCLSQLAHDDGKPMFIW 590 600 610 620 >>XP_011515323 (OMIM: 610874) PREDICTED: speriolin isofo (626 aa) initn: 463 init1: 193 opt: 322 Z-score: 423.4 bits: 86.7 E(85289): 7.6e-17 Smith-Waterman score: 439; 43.8% identity (67.6% similar) in 185 aa overlap (40-186:444-626) 10 20 30 40 50 60 pF1KE0 SESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTV :.:::::::::::::. .:: .::::::: XP_011 SMMEVERKLAHRKTSKFPENPRESKQLAWERLVGEIAFQLDRRILSSIFPERVRLYGFTV 420 430 440 450 460 470 70 80 90 pF1KE0 ANIPEKIEQTSTK-------SLDGS----------------------------VDERKLR .:::::: : . ::.:: .::. . XP_011 SNIPEKIIQLCLSVDCRPVCSLSGSYCELRGSRLELCLWLKHPWASLNPSDHKLDEKLCQ 480 490 500 510 520 530 100 110 120 130 140 150 pF1KE0 ELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAA---LRK .:::::... ::..:::. ::::..: :.:.::::..::.: :. ...: . :.. XP_011 RLTQRYVSVMNRLQSLGYNGRVHPALTEQLVNAYGILRERPELAAS--EGGPYTVDFLQR 540 550 560 570 580 590 160 170 180 pF1KE0 LVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLFAW .:...: : .:.:.::::.:: .:...::::.: : XP_011 VVVETVHPGMLADALLLLSCLSQLAHDDGKPMFIW 600 610 620 >>XP_011515326 (OMIM: 610874) PREDICTED: speriolin isofo (535 aa) initn: 463 init1: 193 opt: 208 Z-score: 273.8 bits: 58.8 E(85289): 1.6e-08 Smith-Waterman score: 414; 43.6% identity (67.4% similar) in 181 aa overlap (40-182:353-531) 10 20 30 40 50 60 pF1KE0 SESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTV :.:::::::::::::. .:: .::::::: XP_011 SMMEVERKLAHRKTSKFPENPRESKQLAWERLVGEIAFQLDRRILSSIFPERVRLYGFTV 330 340 350 360 370 380 70 80 90 pF1KE0 ANIPEKIEQTSTK-------SLDGS----------------------------VDERKLR .:::::: : . ::.:: .::. . XP_011 SNIPEKIIQLCLSVDCRPVCSLSGSYCELRGSRLELCLWLKHPWASLNPSDHKLDEKLCQ 390 400 410 420 430 440 100 110 120 130 140 150 pF1KE0 ELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAA---LRK .:::::... ::..:::. ::::..: :.:.::::..::.: :. ...: . :.. XP_011 RLTQRYVSVMNRLQSLGYNGRVHPALTEQLVNAYGILRERPELAAS--EGGPYTVDFLQR 450 460 470 480 490 500 160 170 180 pF1KE0 LVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLFAW .:...: : .:.:.::::.:: .:...:::: XP_011 VVVETVHPGMLADALLLLSCLSQLAHDDGKPMFIW 510 520 530 >>XP_016868888 (OMIM: 610874) PREDICTED: speriolin isofo (535 aa) initn: 463 init1: 193 opt: 208 Z-score: 273.8 bits: 58.8 E(85289): 1.6e-08 Smith-Waterman score: 414; 43.6% identity (67.4% similar) in 181 aa overlap (40-182:353-531) 10 20 30 40 50 60 pF1KE0 SESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTV :.:::::::::::::. .:: .::::::: XP_016 SMMEVERKLAHRKTSKFPENPRESKQLAWERLVGEIAFQLDRRILSSIFPERVRLYGFTV 330 340 350 360 370 380 70 80 90 pF1KE0 ANIPEKIEQTSTK-------SLDGS----------------------------VDERKLR .:::::: : . ::.:: .::. . XP_016 SNIPEKIIQLCLSVDCRPVCSLSGSYCELRGSRLELCLWLKHPWASLNPSDHKLDEKLCQ 390 400 410 420 430 440 100 110 120 130 140 150 pF1KE0 ELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAA---LRK .:::::... ::..:::. ::::..: :.:.::::..::.: :. ...: . :.. XP_016 RLTQRYVSVMNRLQSLGYNGRVHPALTEQLVNAYGILRERPELAAS--EGGPYTVDFLQR 450 460 470 480 490 500 160 170 180 pF1KE0 LVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLFAW .:...: : .:.:.::::.:: .:...:::: XP_016 VVVETVHPGMLADALLLLSCLSQLAHDDGKPMFIW 510 520 530 186 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 11:38:32 2016 done: Thu Nov 3 11:38:33 2016 Total Scan time: 6.070 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]