Result of FASTA (omim) for
pF1KE0416
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0416, 352 aa
1>>>pF1KE0416 352 - 352 aa - 352 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7672+/-0.000386; mu= 15.8877+/- 0.024
mean_var=129.2712+/-27.360, 0's: 0 Z-trim(115.7): 121 B-trim: 0 in 0/52
Lambda= 0.112804
statistics sampled from 26121 (26256) to 26121 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.683), E-opt: 0.2 (0.308), width: 16
Scan time: 6.160
The best scores are: opt bits E(85289)
NP_078820 (OMIM: 612037) mitochondrial ubiquitin l ( 352) 2348 393.5 3.8e-109
XP_011540439 (OMIM: 612037) PREDICTED: mitochondri ( 313) 2099 352.9 5.5e-97
NP_001243787 (OMIM: 608299) E3 ubiquitin-protein l ( 180) 211 45.4 0.00012
NP_079402 (OMIM: 608299) E3 ubiquitin-protein liga ( 372) 211 45.7 0.00019
NP_919247 (OMIM: 608299) E3 ubiquitin-protein liga ( 373) 211 45.7 0.00019
XP_016870773 (OMIM: 610933,614436) PREDICTED: E3 u ( 460) 203 44.5 0.00054
XP_006717379 (OMIM: 610933,614436) PREDICTED: E3 u ( 690) 203 44.7 0.00071
NP_001177652 (OMIM: 610933,614436) E3 ubiquitin-pr ( 696) 203 44.7 0.00071
XP_016870772 (OMIM: 610933,614436) PREDICTED: E3 u ( 723) 203 44.8 0.00073
NP_001005374 (OMIM: 610933,614436) E3 ubiquitin-pr ( 723) 203 44.8 0.00073
NP_612370 (OMIM: 610933,614436) E3 ubiquitin-prote ( 723) 203 44.8 0.00073
NP_001005373 (OMIM: 610933,614436) E3 ubiquitin-pr ( 723) 203 44.8 0.00073
NP_001017368 (OMIM: 609735) E3 ubiquitin-protein l ( 363) 192 42.6 0.0016
>>NP_078820 (OMIM: 612037) mitochondrial ubiquitin ligas (352 aa)
initn: 2348 init1: 2348 opt: 2348 Z-score: 2080.6 bits: 393.5 E(85289): 3.8e-109
Smith-Waterman score: 2348; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:1-352)
10 20 30 40 50 60
pF1KE0 MESGGRPSLCQFILLGTTSVVTAALYSVYRQKARVSQELKGAKKVHLGEDLKSILSEAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 MESGGRPSLCQFILLGTTSVVTAALYSVYRQKARVSQELKGAKKVHLGEDLKSILSEAPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KCVPYAVIEGAVRSVKETLNSQFVENCKGVIQRLTLQEHKMVWNRTTHLWNDCSKIIHQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 KCVPYAVIEGAVRSVKETLNSQFVENCKGVIQRLTLQEHKMVWNRTTHLWNDCSKIIHQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 TNTVPFDLVPHEDGVDVAVRVLKPLDSVDLGLETVYEKFHPSIQSFTDVIGHYISGERPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 TNTVPFDLVPHEDGVDVAVRVLKPLDSVDLGLETVYEKFHPSIQSFTDVIGHYISGERPK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GIQETEEMLKVGATLTGVGELVLDNNSVRLQPPKQGMQYYLSSQDFDSLLQRQESSVRLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 GIQETEEMLKVGATLTGVGELVLDNNSVRLQPPKQGMQYYLSSQDFDSLLQRQESSVRLW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KVLALVFGFATCATLFFILRKQYLQRQERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 KVLALVFGFATCATLFFILRKQYLQRQERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKS
250 260 270 280 290 300
310 320 330 340 350
pF1KE0 ACVVCLSSFKSCVFLECGHVCSCTECYRALPEPKKCPICRQAITRVIPLYNS
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 ACVVCLSSFKSCVFLECGHVCSCTECYRALPEPKKCPICRQAITRVIPLYNS
310 320 330 340 350
>>XP_011540439 (OMIM: 612037) PREDICTED: mitochondrial u (313 aa)
initn: 2099 init1: 2099 opt: 2099 Z-score: 1862.2 bits: 352.9 E(85289): 5.5e-97
Smith-Waterman score: 2099; 100.0% identity (100.0% similar) in 312 aa overlap (41-352:2-313)
20 30 40 50 60 70
pF1KE0 QFILLGTTSVVTAALYSVYRQKARVSQELKGAKKVHLGEDLKSILSEAPGKCVPYAVIEG
::::::::::::::::::::::::::::::
XP_011 MGAKKVHLGEDLKSILSEAPGKCVPYAVIEG
10 20 30
80 90 100 110 120 130
pF1KE0 AVRSVKETLNSQFVENCKGVIQRLTLQEHKMVWNRTTHLWNDCSKIIHQRTNTVPFDLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVRSVKETLNSQFVENCKGVIQRLTLQEHKMVWNRTTHLWNDCSKIIHQRTNTVPFDLVP
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE0 HEDGVDVAVRVLKPLDSVDLGLETVYEKFHPSIQSFTDVIGHYISGERPKGIQETEEMLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HEDGVDVAVRVLKPLDSVDLGLETVYEKFHPSIQSFTDVIGHYISGERPKGIQETEEMLK
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE0 VGATLTGVGELVLDNNSVRLQPPKQGMQYYLSSQDFDSLLQRQESSVRLWKVLALVFGFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGATLTGVGELVLDNNSVRLQPPKQGMQYYLSSQDFDSLLQRQESSVRLWKVLALVFGFA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE0 TCATLFFILRKQYLQRQERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKSACVVCLSSFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCATLFFILRKQYLQRQERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKSACVVCLSSFK
220 230 240 250 260 270
320 330 340 350
pF1KE0 SCVFLECGHVCSCTECYRALPEPKKCPICRQAITRVIPLYNS
::::::::::::::::::::::::::::::::::::::::::
XP_011 SCVFLECGHVCSCTECYRALPEPKKCPICRQAITRVIPLYNS
280 290 300 310
>>NP_001243787 (OMIM: 608299) E3 ubiquitin-protein ligas (180 aa)
initn: 215 init1: 101 opt: 211 Z-score: 204.5 bits: 45.4 E(85289): 0.00012
Smith-Waterman score: 219; 30.1% identity (63.9% similar) in 133 aa overlap (222-352:62-180)
200 210 220 230 240
pF1KE0 GATLTGVGELVLDNNSVRLQPPKQGMQYYLSSQDFDSLLQRQESSVR-LWKVLALVF-GF
: .:..:: . . ::: : ..:: : ..
NP_001 DDDDDDEDDDDEEENAEDRNPGLSKERVRASLSDLSSLDDVEGMSVRQLKEILARNFVNY
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE0 ATCATLFFILRKQYLQRQERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKSACVVCLSSF
. : . ...: .... .: .:.. . : . .:.:. : : .:...
NP_001 SGCCEKWELVEK----------VNRLYKENEENQKSYGERLQLQDEED-DSLCRICMDAV
100 110 120 130 140
310 320 330 340 350
pF1KE0 KSCVFLECGHVCSCTECYRALPEPKKCPICRQAITRVIPLYNS
.::.:::::. .::.: . . : :::::: ..:.. ...:
NP_001 IDCVLLECGHMVTCTKCGKRMSE---CPICRQYVVRAVHVFKS
150 160 170 180
>>NP_079402 (OMIM: 608299) E3 ubiquitin-protein ligase R (372 aa)
initn: 215 init1: 101 opt: 211 Z-score: 200.8 bits: 45.7 E(85289): 0.00019
Smith-Waterman score: 219; 30.1% identity (63.9% similar) in 133 aa overlap (222-352:254-372)
200 210 220 230 240
pF1KE0 GATLTGVGELVLDNNSVRLQPPKQGMQYYLSSQDFDSLLQRQESSVR-LWKVLALVF-GF
: .:..:: . . ::: : ..:: : ..
NP_079 DDDDDDEDDDDEEENAEDRNPGLSKERVRASLSDLSSLDDVEGMSVRQLKEILARNFVNY
230 240 250 260 270 280
250 260 270 280 290 300
pF1KE0 ATCATLFFILRKQYLQRQERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKSACVVCLSSF
. : . ...: .... .: .:.. . : . .:.:. : : .:...
NP_079 SGCCEKWELVEK----------VNRLYKENEENQKSYGERLQLQDEED-DSLCRICMDAV
290 300 310 320 330
310 320 330 340 350
pF1KE0 KSCVFLECGHVCSCTECYRALPEPKKCPICRQAITRVIPLYNS
.::.:::::. .::.: . . : :::::: ..:.. ...:
NP_079 IDCVLLECGHMVTCTKCGKRMSE---CPICRQYVVRAVHVFKS
340 350 360 370
>>NP_919247 (OMIM: 608299) E3 ubiquitin-protein ligase R (373 aa)
initn: 215 init1: 101 opt: 211 Z-score: 200.8 bits: 45.7 E(85289): 0.00019
Smith-Waterman score: 219; 30.1% identity (63.9% similar) in 133 aa overlap (222-352:255-373)
200 210 220 230 240
pF1KE0 GATLTGVGELVLDNNSVRLQPPKQGMQYYLSSQDFDSLLQRQESSVR-LWKVLALVF-GF
: .:..:: . . ::: : ..:: : ..
NP_919 DDDDDDEDDDDEEENAEDRNPGLSKERVRASLSDLSSLDDVEGMSVRQLKEILARNFVNY
230 240 250 260 270 280
250 260 270 280 290 300
pF1KE0 ATCATLFFILRKQYLQRQERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKSACVVCLSSF
. : . ...: .... .: .:.. . : . .:.:. : : .:...
NP_919 SGCCEKWELVEK----------VNRLYKENEENQKSYGERLQLQDEED-DSLCRICMDAV
290 300 310 320 330
310 320 330 340 350
pF1KE0 KSCVFLECGHVCSCTECYRALPEPKKCPICRQAITRVIPLYNS
.::.:::::. .::.: . . : :::::: ..:.. ...:
NP_919 IDCVLLECGHMVTCTKCGKRMSE---CPICRQYVVRAVHVFKS
340 350 360 370
>>XP_016870773 (OMIM: 610933,614436) PREDICTED: E3 ubiqu (460 aa)
initn: 262 init1: 149 opt: 203 Z-score: 192.7 bits: 44.5 E(85289): 0.00054
Smith-Waterman score: 203; 39.7% identity (60.3% similar) in 73 aa overlap (280-352:390-459)
250 260 270 280 290 300
pF1KE0 ATCATLFFILRKQYLQRQERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKSACVVCLSSF
:: .. : : . : : :::::
XP_016 LRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVRPSAPPAELEVQASECVVCLERE
360 370 380 390 400 410
310 320 330 340 350
pF1KE0 KSCVFLECGHVCSCTECYRALPEPKKCPICRQAITRVIPLYNS
. .::.::::: : .: . : . ::.::: :.. . .:.:
XP_016 AQMIFLNCGHVCCCQQCCQPL---RTCPLCRQDIAQRLRIYHSS
420 430 440 450 460
>>XP_006717379 (OMIM: 610933,614436) PREDICTED: E3 ubiqu (690 aa)
initn: 236 init1: 149 opt: 203 Z-score: 190.6 bits: 44.7 E(85289): 0.00071
Smith-Waterman score: 203; 39.7% identity (60.3% similar) in 73 aa overlap (280-352:620-689)
250 260 270 280 290 300
pF1KE0 ATCATLFFILRKQYLQRQERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKSACVVCLSSF
:: .. : : . : : :::::
XP_006 LRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVRPSAPPAELEVQASECVVCLERE
590 600 610 620 630 640
310 320 330 340 350
pF1KE0 KSCVFLECGHVCSCTECYRALPEPKKCPICRQAITRVIPLYNS
. .::.::::: : .: . : . ::.::: :.. . .:.:
XP_006 AQMIFLNCGHVCCCQQCCQPL---RTCPLCRQDIAQRLRIYHSS
650 660 670 680 690
>>NP_001177652 (OMIM: 610933,614436) E3 ubiquitin-protei (696 aa)
initn: 236 init1: 149 opt: 203 Z-score: 190.6 bits: 44.7 E(85289): 0.00071
Smith-Waterman score: 203; 39.7% identity (60.3% similar) in 73 aa overlap (280-352:626-695)
250 260 270 280 290 300
pF1KE0 ATCATLFFILRKQYLQRQERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKSACVVCLSSF
:: .. : : . : : :::::
NP_001 LRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVRPSAPPAELEVQASECVVCLERE
600 610 620 630 640 650
310 320 330 340 350
pF1KE0 KSCVFLECGHVCSCTECYRALPEPKKCPICRQAITRVIPLYNS
. .::.::::: : .: . : . ::.::: :.. . .:.:
NP_001 AQMIFLNCGHVCCCQQCCQPL---RTCPLCRQDIAQRLRIYHSS
660 670 680 690
>>XP_016870772 (OMIM: 610933,614436) PREDICTED: E3 ubiqu (723 aa)
initn: 236 init1: 149 opt: 203 Z-score: 190.4 bits: 44.8 E(85289): 0.00073
Smith-Waterman score: 203; 39.7% identity (60.3% similar) in 73 aa overlap (280-352:653-722)
250 260 270 280 290 300
pF1KE0 ATCATLFFILRKQYLQRQERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKSACVVCLSSF
:: .. : : . : : :::::
XP_016 LRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVRPSAPPAELEVQASECVVCLERE
630 640 650 660 670 680
310 320 330 340 350
pF1KE0 KSCVFLECGHVCSCTECYRALPEPKKCPICRQAITRVIPLYNS
. .::.::::: : .: . : . ::.::: :.. . .:.:
XP_016 AQMIFLNCGHVCCCQQCCQPL---RTCPLCRQDIAQRLRIYHSS
690 700 710 720
>>NP_001005374 (OMIM: 610933,614436) E3 ubiquitin-protei (723 aa)
initn: 236 init1: 149 opt: 203 Z-score: 190.4 bits: 44.8 E(85289): 0.00073
Smith-Waterman score: 203; 39.7% identity (60.3% similar) in 73 aa overlap (280-352:653-722)
250 260 270 280 290 300
pF1KE0 ATCATLFFILRKQYLQRQERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKSACVVCLSSF
:: .. : : . : : :::::
NP_001 LRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVRPSAPPAELEVQASECVVCLERE
630 640 650 660 670 680
310 320 330 340 350
pF1KE0 KSCVFLECGHVCSCTECYRALPEPKKCPICRQAITRVIPLYNS
. .::.::::: : .: . : . ::.::: :.. . .:.:
NP_001 AQMIFLNCGHVCCCQQCCQPL---RTCPLCRQDIAQRLRIYHSS
690 700 710 720
352 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 11:28:00 2016 done: Thu Nov 3 11:28:01 2016
Total Scan time: 6.160 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]