FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0418, 423 aa 1>>>pF1KE0418 423 - 423 aa - 423 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4145+/-0.000829; mu= 16.6216+/- 0.050 mean_var=68.7231+/-13.644, 0's: 0 Z-trim(107.2): 13 B-trim: 0 in 0/52 Lambda= 0.154712 statistics sampled from 9439 (9449) to 9439 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.29), width: 16 Scan time: 2.790 The best scores are: opt bits E(32554) CCDS5658.1 TMEM130 gene_id:222865|Hs108|chr7 ( 423) 2875 650.8 7.4e-187 CCDS47650.1 TMEM130 gene_id:222865|Hs108|chr7 ( 435) 2505 568.2 5.5e-162 CCDS47649.1 TMEM130 gene_id:222865|Hs108|chr7 ( 321) 1989 452.9 2e-127 >>CCDS5658.1 TMEM130 gene_id:222865|Hs108|chr7 (423 aa) initn: 2875 init1: 2875 opt: 2875 Z-score: 3468.2 bits: 650.8 E(32554): 7.4e-187 Smith-Waterman score: 2875; 100.0% identity (100.0% similar) in 423 aa overlap (1-423:1-423) 10 20 30 40 50 60 pF1KE0 MAQAVWSRLGRILWLACLLPWAPAGVAAGLYELNLTTDSPATTGAVVTISASLVAKDNGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MAQAVWSRLGRILWLACLLPWAPAGVAAGLYELNLTTDSPATTGAVVTISASLVAKDNGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LALPADAHLYRFHWIHTPLVLTGKMEKGLSSTIRVVGHVPGEFPVSVWVTAADCWMCQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 LALPADAHLYRFHWIHTPLVLTGKMEKGLSSTIRVVGHVPGEFPVSVWVTAADCWMCQPV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ARGFVVLPITEFLVGDLVVTQNTSLPWPSSYLTKTVLKVSFLLHDPSNFLKTALFLYSWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 ARGFVVLPITEFLVGDLVVTQNTSLPWPSSYLTKTVLKVSFLLHDPSNFLKTALFLYSWD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 FGDGTQMVTEDSVVYYNYSIIGTFTVKLKVVAEWEEVEPDATRAVKQKTGDFSASLKLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 FGDGTQMVTEDSVVYYNYSIIGTFTVKLKVVAEWEEVEPDATRAVKQKTGDFSASLKLQE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 TLRGIQVLGPTLIQTFQKMTVTLNFLGSPPLTVCWRLKPECLPLEEGECHPVSVASTAYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 TLRGIQVLGPTLIQTFQKMTVTLNFLGSPPLTVCWRLKPECLPLEEGECHPVSVASTAYN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 LTHTFRDPGDYCFSIRAENIISKTHQYHKIQVWPSRIQPAVFAFPCATLITVMLAFIMYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 LTHTFRDPGDYCFSIRAENIISKTHQYHKIQVWPSRIQPAVFAFPCATLITVMLAFIMYM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 TLRNATQQKDMVENPEPPSGVRCCCQMCCGPFLLETPSEYLEIVRENHGLLPPLYKSVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 TLRNATQQKDMVENPEPPSGVRCCCQMCCGPFLLETPSEYLEIVRENHGLLPPLYKSVKT 370 380 390 400 410 420 pF1KE0 YTV ::: CCDS56 YTV >>CCDS47650.1 TMEM130 gene_id:222865|Hs108|chr7 (435 aa) initn: 2505 init1: 2505 opt: 2505 Z-score: 3021.6 bits: 568.2 E(32554): 5.5e-162 Smith-Waterman score: 2841; 97.2% identity (97.2% similar) in 435 aa overlap (1-423:1-435) 10 20 30 40 50 60 pF1KE0 MAQAVWSRLGRILWLACLLPWAPAGVAAGLYELNLTTDSPATTGAVVTISASLVAKDNGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MAQAVWSRLGRILWLACLLPWAPAGVAAGLYELNLTTDSPATTGAVVTISASLVAKDNGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LALPADAHLYRFHWIHTPLVLTGKMEKGLSSTIRVVGHVPGEFPVSVWVTAADCWMCQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LALPADAHLYRFHWIHTPLVLTGKMEKGLSSTIRVVGHVPGEFPVSVWVTAADCWMCQPV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ARGFVVLPITEFLVGDLVVTQNTSLPWPSSYLTKTVLKVSFLLHDPSNFLKTALFLYSWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 ARGFVVLPITEFLVGDLVVTQNTSLPWPSSYLTKTVLKVSFLLHDPSNFLKTALFLYSWD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 FGDGTQMVTEDSVVYYNYSIIGTFTVKLKVVAEWEEVEPDATRAVKQKTGDFSASLKLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 FGDGTQMVTEDSVVYYNYSIIGTFTVKLKVVAEWEEVEPDATRAVKQKTGDFSASLKLQE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 TLRGIQVLGPTLIQTFQKMTVTLNFLGSPPLTVCWRLKPECLPLEEGECHPVSVASTAYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 TLRGIQVLGPTLIQTFQKMTVTLNFLGSPPLTVCWRLKPECLPLEEGECHPVSVASTAYN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 LTHTFRDPGDYCFSIRAENIISKTHQYHKIQVWPSRIQPAVFAFPCATLITVMLAFIMYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LTHTFRDPGDYCFSIRAENIISKTHQYHKIQVWPSRIQPAVFAFPCATLITVMLAFIMYM 310 320 330 340 350 360 370 380 390 400 pF1KE0 TLRNATQQKDMVE------------NPEPPSGVRCCCQMCCGPFLLETPSEYLEIVRENH ::::::::::::: ::::::::::::::::::::::::::::::::::: CCDS47 TLRNATQQKDMVEVADFDFSPMSDKNPEPPSGVRCCCQMCCGPFLLETPSEYLEIVRENH 370 380 390 400 410 420 410 420 pF1KE0 GLLPPLYKSVKTYTV ::::::::::::::: CCDS47 GLLPPLYKSVKTYTV 430 >>CCDS47649.1 TMEM130 gene_id:222865|Hs108|chr7 (321 aa) initn: 1989 init1: 1989 opt: 1989 Z-score: 2401.2 bits: 452.9 E(32554): 2e-127 Smith-Waterman score: 1989; 100.0% identity (100.0% similar) in 293 aa overlap (131-423:29-321) 110 120 130 140 150 160 pF1KE0 GEFPVSVWVTAADCWMCQPVARGFVVLPITEFLVGDLVVTQNTSLPWPSSYLTKTVLKVS :::::::::::::::::::::::::::::: CCDS47 MAQAVWSRLGRILWLACLLPWAPAGVAAEFLVGDLVVTQNTSLPWPSSYLTKTVLKVS 10 20 30 40 50 170 180 190 200 210 220 pF1KE0 FLLHDPSNFLKTALFLYSWDFGDGTQMVTEDSVVYYNYSIIGTFTVKLKVVAEWEEVEPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 FLLHDPSNFLKTALFLYSWDFGDGTQMVTEDSVVYYNYSIIGTFTVKLKVVAEWEEVEPD 60 70 80 90 100 110 230 240 250 260 270 280 pF1KE0 ATRAVKQKTGDFSASLKLQETLRGIQVLGPTLIQTFQKMTVTLNFLGSPPLTVCWRLKPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 ATRAVKQKTGDFSASLKLQETLRGIQVLGPTLIQTFQKMTVTLNFLGSPPLTVCWRLKPE 120 130 140 150 160 170 290 300 310 320 330 340 pF1KE0 CLPLEEGECHPVSVASTAYNLTHTFRDPGDYCFSIRAENIISKTHQYHKIQVWPSRIQPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 CLPLEEGECHPVSVASTAYNLTHTFRDPGDYCFSIRAENIISKTHQYHKIQVWPSRIQPA 180 190 200 210 220 230 350 360 370 380 390 400 pF1KE0 VFAFPCATLITVMLAFIMYMTLRNATQQKDMVENPEPPSGVRCCCQMCCGPFLLETPSEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 VFAFPCATLITVMLAFIMYMTLRNATQQKDMVENPEPPSGVRCCCQMCCGPFLLETPSEY 240 250 260 270 280 290 410 420 pF1KE0 LEIVRENHGLLPPLYKSVKTYTV ::::::::::::::::::::::: CCDS47 LEIVRENHGLLPPLYKSVKTYTV 300 310 320 423 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 11:17:58 2016 done: Thu Nov 3 11:17:59 2016 Total Scan time: 2.790 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]