FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0424, 470 aa 1>>>pF1KE0424 470 - 470 aa - 470 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2961+/-0.000392; mu= 17.6803+/- 0.024 mean_var=65.7133+/-13.632, 0's: 0 Z-trim(112.3): 5 B-trim: 977 in 1/50 Lambda= 0.158215 statistics sampled from 21217 (21221) to 21217 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.611), E-opt: 0.2 (0.249), width: 16 Scan time: 9.800 The best scores are: opt bits E(85289) NP_001174 (OMIM: 300197,300972) V-type proton ATPa ( 470) 3096 715.8 6.3e-206 XP_011529481 (OMIM: 300197,300972) PREDICTED: V-ty ( 281) 1870 435.8 7.1e-122 >>NP_001174 (OMIM: 300197,300972) V-type proton ATPase s (470 aa) initn: 3096 init1: 3096 opt: 3096 Z-score: 3818.1 bits: 715.8 E(85289): 6.3e-206 Smith-Waterman score: 3096; 100.0% identity (100.0% similar) in 470 aa overlap (1-470:1-470) 10 20 30 40 50 60 pF1KE0 MMAAMATARVRMGPRCAQALWRMPWLPVFLSLAAAAAAAAAEQQVPLVLWSSDRDLWAPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMAAMATARVRMGPRCAQALWRMPWLPVFLSLAAAAAAAAAEQQVPLVLWSSDRDLWAPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ADTHEGHITSDLQLSTYLDPALELGPRNVLLFLQDKLSIEDFTAYGGVFGNKQDSAFSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADTHEGHITSDLQLSTYLDPALELGPRNVLLFLQDKLSIEDFTAYGGVFGNKQDSAFSNL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ENALDLAPSSLVLPAVDWYAVSTLTTYLQEKLGASPLHVDLATLRELKLNASLPALLLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENALDLAPSSLVLPAVDWYAVSTLTTYLQEKLGASPLHVDLATLRELKLNASLPALLLIR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LPYTASSGLMAPREVLTGNDEVIGQVLSTLKSEDVPYTAALTAVRPSRVARDVAVVAGGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPYTASSGLMAPREVLTGNDEVIGQVLSTLKSEDVPYTAALTAVRPSRVARDVAVVAGGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GRQLLQKQPVSPVIHPPVSYNDTAPRILFWAQNFSVAYKDQWEDLTPLTFGVQELNLTGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRQLLQKQPVSPVIHPPVSYNDTAPRILFWAQNFSVAYKDQWEDLTPLTFGVQELNLTGS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 FWNDSFARLSLTYERLFGTTVTFKFILANRLYPVSARHWFTMERLEVHSNGSVAYFNASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FWNDSFARLSLTYERLFGTTVTFKFILANRLYPVSARHWFTMERLEVHSNGSVAYFNASQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 VTGPSIYSFHCEYVSSLSKKGSLLVARTQPSPWQMMLQDFQIQAFNVMGEQFSYASDCAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTGPSIYSFHCEYVSSLSKKGSLLVARTQPSPWQMMLQDFQIQAFNVMGEQFSYASDCAS 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 FFSPGIWMGLLTSLFMLFIFTYGLHMILSLKTMDRFDDHKGPTISLTQIV :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFSPGIWMGLLTSLFMLFIFTYGLHMILSLKTMDRFDDHKGPTISLTQIV 430 440 450 460 470 >>XP_011529481 (OMIM: 300197,300972) PREDICTED: V-type p (281 aa) initn: 1870 init1: 1870 opt: 1870 Z-score: 2309.0 bits: 435.8 E(85289): 7.1e-122 Smith-Waterman score: 1870; 100.0% identity (100.0% similar) in 281 aa overlap (190-470:1-281) 160 170 180 190 200 210 pF1KE0 DLATLRELKLNASLPALLLIRLPYTASSGLMAPREVLTGNDEVIGQVLSTLKSEDVPYTA :::::::::::::::::::::::::::::: XP_011 MAPREVLTGNDEVIGQVLSTLKSEDVPYTA 10 20 30 220 230 240 250 260 270 pF1KE0 ALTAVRPSRVARDVAVVAGGLGRQLLQKQPVSPVIHPPVSYNDTAPRILFWAQNFSVAYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALTAVRPSRVARDVAVVAGGLGRQLLQKQPVSPVIHPPVSYNDTAPRILFWAQNFSVAYK 40 50 60 70 80 90 280 290 300 310 320 330 pF1KE0 DQWEDLTPLTFGVQELNLTGSFWNDSFARLSLTYERLFGTTVTFKFILANRLYPVSARHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQWEDLTPLTFGVQELNLTGSFWNDSFARLSLTYERLFGTTVTFKFILANRLYPVSARHW 100 110 120 130 140 150 340 350 360 370 380 390 pF1KE0 FTMERLEVHSNGSVAYFNASQVTGPSIYSFHCEYVSSLSKKGSLLVARTQPSPWQMMLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FTMERLEVHSNGSVAYFNASQVTGPSIYSFHCEYVSSLSKKGSLLVARTQPSPWQMMLQD 160 170 180 190 200 210 400 410 420 430 440 450 pF1KE0 FQIQAFNVMGEQFSYASDCASFFSPGIWMGLLTSLFMLFIFTYGLHMILSLKTMDRFDDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FQIQAFNVMGEQFSYASDCASFFSPGIWMGLLTSLFMLFIFTYGLHMILSLKTMDRFDDH 220 230 240 250 260 270 460 470 pF1KE0 KGPTISLTQIV ::::::::::: XP_011 KGPTISLTQIV 280 470 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 10:39:51 2016 done: Thu Nov 3 10:39:52 2016 Total Scan time: 9.800 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]