FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0430, 417 aa 1>>>pF1KE0430 417 - 417 aa - 417 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7769+/-0.000873; mu= 3.4530+/- 0.053 mean_var=251.0123+/-50.212, 0's: 0 Z-trim(116.3): 111 B-trim: 0 in 0/52 Lambda= 0.080952 statistics sampled from 16791 (16912) to 16791 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.812), E-opt: 0.2 (0.52), width: 16 Scan time: 3.320 The best scores are: opt bits E(32554) CCDS2593.1 CRELD1 gene_id:78987|Hs108|chr3 ( 420) 3073 371.5 8.4e-103 CCDS33693.1 CRELD1 gene_id:78987|Hs108|chr3 ( 422) 2650 322.1 6.3e-88 CCDS14082.1 CRELD2 gene_id:79174|Hs108|chr22 ( 353) 1299 164.2 1.7e-40 CCDS63515.1 CRELD2 gene_id:79174|Hs108|chr22 ( 321) 1057 135.9 5.2e-32 CCDS63516.1 CRELD2 gene_id:79174|Hs108|chr22 ( 325) 953 123.8 2.4e-28 CCDS46730.1 CRELD2 gene_id:79174|Hs108|chr22 ( 402) 819 108.2 1.4e-23 >>CCDS2593.1 CRELD1 gene_id:78987|Hs108|chr3 (420 aa) initn: 3073 init1: 3073 opt: 3073 Z-score: 1959.1 bits: 371.5 E(32554): 8.4e-103 Smith-Waterman score: 3073; 99.3% identity (99.5% similar) in 417 aa overlap (1-417:1-417) 10 20 30 40 50 60 pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 MAPWPPKGLVPAMLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH ::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEMTE ::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::: CCDS25 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTE 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR 370 380 390 400 410 420 >>CCDS33693.1 CRELD1 gene_id:78987|Hs108|chr3 (422 aa) initn: 2643 init1: 2643 opt: 2650 Z-score: 1692.1 bits: 322.1 E(32554): 6.3e-88 Smith-Waterman score: 2650; 96.1% identity (98.3% similar) in 361 aa overlap (1-361:1-361) 10 20 30 40 50 60 pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MAPWPPKGLVPAMLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH ::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEMTE ::::::::::::::::::::::::::::::::::: ::::::::::::: . .....: CCDS33 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPGAFPILTDLTP 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI . CCDS33 ETTRRWKLGSHPHSTYVKMKMQRDEATFPGLYGKQVAKLGSQSRQSDRGTRLIHSQQASS 370 380 390 400 410 420 >>CCDS14082.1 CRELD2 gene_id:79174|Hs108|chr22 (353 aa) initn: 1200 init1: 1200 opt: 1299 Z-score: 840.3 bits: 164.2 E(32554): 1.7e-40 Smith-Waterman score: 1299; 49.2% identity (73.2% similar) in 321 aa overlap (26-344:13-331) 10 20 30 40 50 60 pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL :. : : :... .: ::: ::::::.::.:. CCDS14 MRLPRRAALGLLPLLLLLPPAPEAAK--KPTPCHRCRGLVDKFNQGM 10 20 30 40 70 80 90 100 110 120 pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW : . :::::::::::..::::..:: ::.:.:::.: .:::::...:: .:: .:.:: CCDS14 VDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWW 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH .. .. ::::.:.: .::.:: ::.::.:: : ::..:::.: :.: :.:.: :.: CCDS14 LQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGS 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH : :. :: : : .: ::: . :: .: .:.:: : ::: . .: .:. ::.: . CCDS14 CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDE 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG :::.:::..: :.: ::: :..::: :..: ..:.:: : ::: ::.: :: . CCDS14 GACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREH 230 240 250 260 270 280 310 320 330 340 350 pF1KE0 SKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEM ..: ::::: ..: .:..: :: :.: :.: .: .. : :: CCDS14 GQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPT 290 300 310 320 330 340 360 370 380 390 400 410 pF1KE0 TEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI CCDS14 QLPSREDL 350 >>CCDS63515.1 CRELD2 gene_id:79174|Hs108|chr22 (321 aa) initn: 1093 init1: 1036 opt: 1057 Z-score: 688.1 bits: 135.9 E(32554): 5.2e-32 Smith-Waterman score: 1092; 44.9% identity (66.4% similar) in 321 aa overlap (26-344:13-299) 10 20 30 40 50 60 pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL :. : : :... .: ::: ::::::.::.:. CCDS63 MRLPRRAALGLLPLLLLLPPAPEAAK--KPTPCHRCRGLVDKFNQGM 10 20 30 40 70 80 90 100 110 120 pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW : . :::::::::::..::::..:: ::.:.:::.: .:::::...:: .:: .:.:: CCDS63 VDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWW 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH .. .. ::::.:.: .::.:: ::.::.:: : ::..:::.: :.: :.:.: :.: CCDS63 LQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGS 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH : :. :: : : .: ::: . :: .: .:.:: : ::: . .: .:. ::.: . CCDS63 CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDE 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG :::.:::..: :.: ::: :..::: :. CCDS63 GACVDVDECAAEPPPCSAAQFCKNANGSYTCE---------------------------- 230 240 250 310 320 330 340 350 pF1KE0 SKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEM ::::: ..: .:..: :: :.: :.: .: .. : :: CCDS63 ----DVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPT 260 270 280 290 300 310 360 370 380 390 400 410 pF1KE0 TEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI CCDS63 QLPSREDL 320 >>CCDS63516.1 CRELD2 gene_id:79174|Hs108|chr22 (325 aa) initn: 914 init1: 914 opt: 953 Z-score: 622.4 bits: 123.8 E(32554): 2.4e-28 Smith-Waterman score: 1118; 45.2% identity (66.7% similar) in 321 aa overlap (26-344:13-303) 10 20 30 40 50 60 pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL :. : : :... .: ::: ::::::.::.:. CCDS63 MRLPRRAALGLLPLLLLLPPAPEAAK--KPTPCHRCRGLVDKFNQGM 10 20 30 40 70 80 90 100 110 120 pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW : . :::::::::::..::::..:: ::.:.:::.: .:::::...:: .:: .:.:: CCDS63 VDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWW 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH .. .. ::::.:.: .::.:: ::.::.:: : ::..:::.: :.: :.:.: :.: CCDS63 LQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGS 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH : :. :: : : .: ::: . :: .: .:.:: : ::: . .: .:. ::.: CCDS63 CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLD- 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG ::: : .: ..:.:: : ::: ::.: :: . CCDS63 -----------EGA----------------CVECDSSCVGCTGEGPGNCKECISGYAREH 230 240 250 310 320 330 340 350 pF1KE0 SKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEM ..: ::::: ..: .:..: :: :.: :.: .: .. : :: CCDS63 GQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPT 260 270 280 290 300 310 360 370 380 390 400 410 pF1KE0 TEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI CCDS63 QLPSREDL 320 >>CCDS46730.1 CRELD2 gene_id:79174|Hs108|chr22 (402 aa) initn: 1243 init1: 802 opt: 819 Z-score: 536.6 bits: 108.2 E(32554): 1.4e-23 Smith-Waterman score: 1194; 43.0% identity (64.1% similar) in 370 aa overlap (26-344:13-380) 10 20 30 40 50 60 pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL :. : : :... .: ::: ::::::.::.:. CCDS46 MRLPRRAALGLLPLLLLLPPAPEAAK--KPTPCHRCRGLVDKFNQGM 10 20 30 40 70 80 90 100 110 120 pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW : . :::::::::::..::::..:: ::.:.:::.: .:::::...:: .:: .:.:: CCDS46 VDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWW 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH .. .. ::::.:.: .::.:: ::.::.:: : ::..:::.: :.: :.:.: :.: CCDS46 LQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGS 110 120 130 140 150 160 190 200 210 pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCS---------------------------- : :. :: : : .: ::: . :: .: .:. CCDS46 CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIR 170 180 190 200 210 220 220 230 240 250 pF1KE0 ----------------ACFGP-----CARCSGPEESNCLQCKKGWALHHLKCVDIDECGT : :.: : ::: . .: .:. ::.: . :::.:::.. CCDS46 GRNTHTQPGYSSRVWIAAFSPACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAA 230 240 250 260 270 280 260 270 280 290 300 310 pF1KE0 EGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECET : :.: ::: :..::: :..: ..:.:: : ::: ::.: :: . ..: ::::: CCDS46 EPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSL 290 300 310 320 330 340 320 330 340 350 360 pF1KE0 --EVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEMTEDELVVLQQM ..: .:..: :: :.: :.: .: .. : :: CCDS46 AEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPTQLPSREDL 350 360 370 380 390 400 370 380 390 400 410 pF1KE0 FFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI 417 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 09:45:57 2016 done: Thu Nov 3 09:45:58 2016 Total Scan time: 3.320 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]