FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0430, 417 aa
1>>>pF1KE0430 417 - 417 aa - 417 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7769+/-0.000873; mu= 3.4530+/- 0.053
mean_var=251.0123+/-50.212, 0's: 0 Z-trim(116.3): 111 B-trim: 0 in 0/52
Lambda= 0.080952
statistics sampled from 16791 (16912) to 16791 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.812), E-opt: 0.2 (0.52), width: 16
Scan time: 3.320
The best scores are: opt bits E(32554)
CCDS2593.1 CRELD1 gene_id:78987|Hs108|chr3 ( 420) 3073 371.5 8.4e-103
CCDS33693.1 CRELD1 gene_id:78987|Hs108|chr3 ( 422) 2650 322.1 6.3e-88
CCDS14082.1 CRELD2 gene_id:79174|Hs108|chr22 ( 353) 1299 164.2 1.7e-40
CCDS63515.1 CRELD2 gene_id:79174|Hs108|chr22 ( 321) 1057 135.9 5.2e-32
CCDS63516.1 CRELD2 gene_id:79174|Hs108|chr22 ( 325) 953 123.8 2.4e-28
CCDS46730.1 CRELD2 gene_id:79174|Hs108|chr22 ( 402) 819 108.2 1.4e-23
>>CCDS2593.1 CRELD1 gene_id:78987|Hs108|chr3 (420 aa)
initn: 3073 init1: 3073 opt: 3073 Z-score: 1959.1 bits: 371.5 E(32554): 8.4e-103
Smith-Waterman score: 3073; 99.3% identity (99.5% similar) in 417 aa overlap (1-417:1-417)
10 20 30 40 50 60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 MAPWPPKGLVPAMLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEMTE
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
CCDS25 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTE
310 320 330 340 350 360
370 380 390 400 410
pF1KE0 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR
370 380 390 400 410 420
>>CCDS33693.1 CRELD1 gene_id:78987|Hs108|chr3 (422 aa)
initn: 2643 init1: 2643 opt: 2650 Z-score: 1692.1 bits: 322.1 E(32554): 6.3e-88
Smith-Waterman score: 2650; 96.1% identity (98.3% similar) in 361 aa overlap (1-361:1-361)
10 20 30 40 50 60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MAPWPPKGLVPAMLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEMTE
::::::::::::::::::::::::::::::::::: ::::::::::::: . .....:
CCDS33 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPGAFPILTDLTP
310 320 330 340 350 360
370 380 390 400 410
pF1KE0 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
.
CCDS33 ETTRRWKLGSHPHSTYVKMKMQRDEATFPGLYGKQVAKLGSQSRQSDRGTRLIHSQQASS
370 380 390 400 410 420
>>CCDS14082.1 CRELD2 gene_id:79174|Hs108|chr22 (353 aa)
initn: 1200 init1: 1200 opt: 1299 Z-score: 840.3 bits: 164.2 E(32554): 1.7e-40
Smith-Waterman score: 1299; 49.2% identity (73.2% similar) in 321 aa overlap (26-344:13-331)
10 20 30 40 50 60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
:. : : :... .: ::: ::::::.::.:.
CCDS14 MRLPRRAALGLLPLLLLLPPAPEAAK--KPTPCHRCRGLVDKFNQGM
10 20 30 40
70 80 90 100 110 120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
: . :::::::::::..::::..:: ::.:.:::.: .:::::...:: .:: .:.::
CCDS14 VDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWW
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
.. .. ::::.:.: .::.:: ::.::.:: : ::..:::.: :.: :.:.: :.:
CCDS14 LQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGS
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
: :. :: : : .: ::: . :: .: .:.:: : ::: . .: .:. ::.: .
CCDS14 CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
:::.:::..: :.: ::: :..::: :..: ..:.:: : ::: ::.: :: .
CCDS14 GACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREH
230 240 250 260 270 280
310 320 330 340 350
pF1KE0 SKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEM
..: ::::: ..: .:..: :: :.: :.: .: .. : ::
CCDS14 GQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPT
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE0 TEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
CCDS14 QLPSREDL
350
>>CCDS63515.1 CRELD2 gene_id:79174|Hs108|chr22 (321 aa)
initn: 1093 init1: 1036 opt: 1057 Z-score: 688.1 bits: 135.9 E(32554): 5.2e-32
Smith-Waterman score: 1092; 44.9% identity (66.4% similar) in 321 aa overlap (26-344:13-299)
10 20 30 40 50 60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
:. : : :... .: ::: ::::::.::.:.
CCDS63 MRLPRRAALGLLPLLLLLPPAPEAAK--KPTPCHRCRGLVDKFNQGM
10 20 30 40
70 80 90 100 110 120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
: . :::::::::::..::::..:: ::.:.:::.: .:::::...:: .:: .:.::
CCDS63 VDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWW
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
.. .. ::::.:.: .::.:: ::.::.:: : ::..:::.: :.: :.:.: :.:
CCDS63 LQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGS
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
: :. :: : : .: ::: . :: .: .:.:: : ::: . .: .:. ::.: .
CCDS63 CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
:::.:::..: :.: ::: :..::: :.
CCDS63 GACVDVDECAAEPPPCSAAQFCKNANGSYTCE----------------------------
230 240 250
310 320 330 340 350
pF1KE0 SKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEM
::::: ..: .:..: :: :.: :.: .: .. : ::
CCDS63 ----DVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPT
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE0 TEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
CCDS63 QLPSREDL
320
>>CCDS63516.1 CRELD2 gene_id:79174|Hs108|chr22 (325 aa)
initn: 914 init1: 914 opt: 953 Z-score: 622.4 bits: 123.8 E(32554): 2.4e-28
Smith-Waterman score: 1118; 45.2% identity (66.7% similar) in 321 aa overlap (26-344:13-303)
10 20 30 40 50 60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
:. : : :... .: ::: ::::::.::.:.
CCDS63 MRLPRRAALGLLPLLLLLPPAPEAAK--KPTPCHRCRGLVDKFNQGM
10 20 30 40
70 80 90 100 110 120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
: . :::::::::::..::::..:: ::.:.:::.: .:::::...:: .:: .:.::
CCDS63 VDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWW
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
.. .. ::::.:.: .::.:: ::.::.:: : ::..:::.: :.: :.:.: :.:
CCDS63 LQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGS
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
: :. :: : : .: ::: . :: .: .:.:: : ::: . .: .:. ::.:
CCDS63 CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLD-
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
::: : .: ..:.:: : ::: ::.: :: .
CCDS63 -----------EGA----------------CVECDSSCVGCTGEGPGNCKECISGYAREH
230 240 250
310 320 330 340 350
pF1KE0 SKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEM
..: ::::: ..: .:..: :: :.: :.: .: .. : ::
CCDS63 GQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPT
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE0 TEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
CCDS63 QLPSREDL
320
>>CCDS46730.1 CRELD2 gene_id:79174|Hs108|chr22 (402 aa)
initn: 1243 init1: 802 opt: 819 Z-score: 536.6 bits: 108.2 E(32554): 1.4e-23
Smith-Waterman score: 1194; 43.0% identity (64.1% similar) in 370 aa overlap (26-344:13-380)
10 20 30 40 50 60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
:. : : :... .: ::: ::::::.::.:.
CCDS46 MRLPRRAALGLLPLLLLLPPAPEAAK--KPTPCHRCRGLVDKFNQGM
10 20 30 40
70 80 90 100 110 120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
: . :::::::::::..::::..:: ::.:.:::.: .:::::...:: .:: .:.::
CCDS46 VDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWW
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
.. .. ::::.:.: .::.:: ::.::.:: : ::..:::.: :.: :.:.: :.:
CCDS46 LQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGS
110 120 130 140 150 160
190 200 210
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCS----------------------------
: :. :: : : .: ::: . :: .: .:.
CCDS46 CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIR
170 180 190 200 210 220
220 230 240 250
pF1KE0 ----------------ACFGP-----CARCSGPEESNCLQCKKGWALHHLKCVDIDECGT
: :.: : ::: . .: .:. ::.: . :::.:::..
CCDS46 GRNTHTQPGYSSRVWIAAFSPACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAA
230 240 250 260 270 280
260 270 280 290 300 310
pF1KE0 EGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECET
: :.: ::: :..::: :..: ..:.:: : ::: ::.: :: . ..: :::::
CCDS46 EPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSL
290 300 310 320 330 340
320 330 340 350 360
pF1KE0 --EVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEMTEDELVVLQQM
..: .:..: :: :.: :.: .: .. : ::
CCDS46 AEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPTQLPSREDL
350 360 370 380 390 400
370 380 390 400 410
pF1KE0 FFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
417 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 09:45:57 2016 done: Thu Nov 3 09:45:58 2016
Total Scan time: 3.320 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]