FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0431, 336 aa 1>>>pF1KE0431 336 - 336 aa - 336 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6250+/-0.00046; mu= 14.5283+/- 0.028 mean_var=67.4740+/-13.468, 0's: 0 Z-trim(109.1): 59 B-trim: 79 in 2/49 Lambda= 0.156137 statistics sampled from 17196 (17238) to 17196 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.563), E-opt: 0.2 (0.202), width: 16 Scan time: 7.200 The best scores are: opt bits E(85289) NP_001002010 (OMIM: 266120,606224) cytosolic 5'-nu ( 336) 2175 499.2 5.1e-141 NP_001002009 (OMIM: 266120,606224) cytosolic 5'-nu ( 297) 1878 432.3 6.3e-121 NP_057573 (OMIM: 266120,606224) cytosolic 5'-nucle ( 297) 1878 432.3 6.3e-121 XP_011513711 (OMIM: 266120,606224) PREDICTED: cyto ( 285) 1866 429.6 3.9e-120 NP_001159590 (OMIM: 266120,606224) cytosolic 5'-nu ( 285) 1866 429.6 3.9e-120 >>NP_001002010 (OMIM: 266120,606224) cytosolic 5'-nucleo (336 aa) initn: 2175 init1: 2175 opt: 2175 Z-score: 2652.8 bits: 499.2 E(85289): 5.1e-141 Smith-Waterman score: 2175; 100.0% identity (100.0% similar) in 336 aa overlap (1-336:1-336) 10 20 30 40 50 60 pF1KE0 MRAPSMDRAAVARVGAVASASVCALVAGVVLAQYIFTLKRKTGRKTKIIEMMPEFQKSSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRAPSMDRAAVARVGAVASASVCALVAGVVLAQYIFTLKRKTGRKTKIIEMMPEFQKSSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RIKNPTRVEEIICGLIKGGAAKLQIITDFDMTLSRFSYKGKRCPTCHNIIDNCKLVTDEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIKNPTRVEEIICGLIKGGAAKLQIITDFDMTLSRFSYKGKRCPTCHNIIDNCKLVTDEC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RKKLLQLKEKYYAIEVDPVLTVEEKYPYMVEWYTKSHGLLVQQALPKAKLKEIVAESDVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKKLLQLKEKYYAIEVDPVLTVEEKYPYMVEWYTKSHGLLVQQALPKAKLKEIVAESDVM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LKEGYENFFDKLQQHSIPVFIFSAGIGDVLEEVIRQAGVYHPNVKVVSNFMDFDETGVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKEGYENFFDKLQQHSIPVFIFSAGIGDVLEEVIRQAGVYHPNVKVVSNFMDFDETGVLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GFKGELIHVFNKHDGALRNTEYFNQLKDNSNIILLGDSQGDLRMADGVANVEHILKIGYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFKGELIHVFNKHDGALRNTEYFNQLKDNSNIILLGDSQGDLRMADGVANVEHILKIGYL 250 260 270 280 290 300 310 320 330 pF1KE0 NDRVDELLEKYMDSYDIVLVQDESLEVANSILQKIL :::::::::::::::::::::::::::::::::::: NP_001 NDRVDELLEKYMDSYDIVLVQDESLEVANSILQKIL 310 320 330 >>NP_001002009 (OMIM: 266120,606224) cytosolic 5'-nucleo (297 aa) initn: 1878 init1: 1878 opt: 1878 Z-score: 2292.1 bits: 432.3 E(85289): 6.3e-121 Smith-Waterman score: 1878; 99.3% identity (100.0% similar) in 288 aa overlap (49-336:10-297) 20 30 40 50 60 70 pF1KE0 SASVCALVAGVVLAQYIFTLKRKTGRKTKIIEMMPEFQKSSVRIKNPTRVEEIICGLIKG ..:::::::::::::::::::::::::::: NP_001 MTNQESAVHVKMMPEFQKSSVRIKNPTRVEEIICGLIKG 10 20 30 80 90 100 110 120 130 pF1KE0 GAAKLQIITDFDMTLSRFSYKGKRCPTCHNIIDNCKLVTDECRKKLLQLKEKYYAIEVDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAAKLQIITDFDMTLSRFSYKGKRCPTCHNIIDNCKLVTDECRKKLLQLKEKYYAIEVDP 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE0 VLTVEEKYPYMVEWYTKSHGLLVQQALPKAKLKEIVAESDVMLKEGYENFFDKLQQHSIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLTVEEKYPYMVEWYTKSHGLLVQQALPKAKLKEIVAESDVMLKEGYENFFDKLQQHSIP 100 110 120 130 140 150 200 210 220 230 240 250 pF1KE0 VFIFSAGIGDVLEEVIRQAGVYHPNVKVVSNFMDFDETGVLKGFKGELIHVFNKHDGALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFIFSAGIGDVLEEVIRQAGVYHPNVKVVSNFMDFDETGVLKGFKGELIHVFNKHDGALR 160 170 180 190 200 210 260 270 280 290 300 310 pF1KE0 NTEYFNQLKDNSNIILLGDSQGDLRMADGVANVEHILKIGYLNDRVDELLEKYMDSYDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTEYFNQLKDNSNIILLGDSQGDLRMADGVANVEHILKIGYLNDRVDELLEKYMDSYDIV 220 230 240 250 260 270 320 330 pF1KE0 LVQDESLEVANSILQKIL :::::::::::::::::: NP_001 LVQDESLEVANSILQKIL 280 290 >>NP_057573 (OMIM: 266120,606224) cytosolic 5'-nucleotid (297 aa) initn: 1878 init1: 1878 opt: 1878 Z-score: 2292.1 bits: 432.3 E(85289): 6.3e-121 Smith-Waterman score: 1878; 99.3% identity (100.0% similar) in 288 aa overlap (49-336:10-297) 20 30 40 50 60 70 pF1KE0 SASVCALVAGVVLAQYIFTLKRKTGRKTKIIEMMPEFQKSSVRIKNPTRVEEIICGLIKG ..:::::::::::::::::::::::::::: NP_057 MTNQESAVHVKMMPEFQKSSVRIKNPTRVEEIICGLIKG 10 20 30 80 90 100 110 120 130 pF1KE0 GAAKLQIITDFDMTLSRFSYKGKRCPTCHNIIDNCKLVTDECRKKLLQLKEKYYAIEVDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 GAAKLQIITDFDMTLSRFSYKGKRCPTCHNIIDNCKLVTDECRKKLLQLKEKYYAIEVDP 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE0 VLTVEEKYPYMVEWYTKSHGLLVQQALPKAKLKEIVAESDVMLKEGYENFFDKLQQHSIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 VLTVEEKYPYMVEWYTKSHGLLVQQALPKAKLKEIVAESDVMLKEGYENFFDKLQQHSIP 100 110 120 130 140 150 200 210 220 230 240 250 pF1KE0 VFIFSAGIGDVLEEVIRQAGVYHPNVKVVSNFMDFDETGVLKGFKGELIHVFNKHDGALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 VFIFSAGIGDVLEEVIRQAGVYHPNVKVVSNFMDFDETGVLKGFKGELIHVFNKHDGALR 160 170 180 190 200 210 260 270 280 290 300 310 pF1KE0 NTEYFNQLKDNSNIILLGDSQGDLRMADGVANVEHILKIGYLNDRVDELLEKYMDSYDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 NTEYFNQLKDNSNIILLGDSQGDLRMADGVANVEHILKIGYLNDRVDELLEKYMDSYDIV 220 230 240 250 260 270 320 330 pF1KE0 LVQDESLEVANSILQKIL :::::::::::::::::: NP_057 LVQDESLEVANSILQKIL 280 290 >>XP_011513711 (OMIM: 266120,606224) PREDICTED: cytosoli (285 aa) initn: 1866 init1: 1866 opt: 1866 Z-score: 2277.7 bits: 429.6 E(85289): 3.9e-120 Smith-Waterman score: 1866; 100.0% identity (100.0% similar) in 285 aa overlap (52-336:1-285) 30 40 50 60 70 80 pF1KE0 VCALVAGVVLAQYIFTLKRKTGRKTKIIEMMPEFQKSSVRIKNPTRVEEIICGLIKGGAA :::::::::::::::::::::::::::::: XP_011 MPEFQKSSVRIKNPTRVEEIICGLIKGGAA 10 20 30 90 100 110 120 130 140 pF1KE0 KLQIITDFDMTLSRFSYKGKRCPTCHNIIDNCKLVTDECRKKLLQLKEKYYAIEVDPVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLQIITDFDMTLSRFSYKGKRCPTCHNIIDNCKLVTDECRKKLLQLKEKYYAIEVDPVLT 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE0 VEEKYPYMVEWYTKSHGLLVQQALPKAKLKEIVAESDVMLKEGYENFFDKLQQHSIPVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEEKYPYMVEWYTKSHGLLVQQALPKAKLKEIVAESDVMLKEGYENFFDKLQQHSIPVFI 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE0 FSAGIGDVLEEVIRQAGVYHPNVKVVSNFMDFDETGVLKGFKGELIHVFNKHDGALRNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSAGIGDVLEEVIRQAGVYHPNVKVVSNFMDFDETGVLKGFKGELIHVFNKHDGALRNTE 160 170 180 190 200 210 270 280 290 300 310 320 pF1KE0 YFNQLKDNSNIILLGDSQGDLRMADGVANVEHILKIGYLNDRVDELLEKYMDSYDIVLVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YFNQLKDNSNIILLGDSQGDLRMADGVANVEHILKIGYLNDRVDELLEKYMDSYDIVLVQ 220 230 240 250 260 270 330 pF1KE0 DESLEVANSILQKIL ::::::::::::::: XP_011 DESLEVANSILQKIL 280 >>NP_001159590 (OMIM: 266120,606224) cytosolic 5'-nucleo (285 aa) initn: 1866 init1: 1866 opt: 1866 Z-score: 2277.7 bits: 429.6 E(85289): 3.9e-120 Smith-Waterman score: 1866; 100.0% identity (100.0% similar) in 285 aa overlap (52-336:1-285) 30 40 50 60 70 80 pF1KE0 VCALVAGVVLAQYIFTLKRKTGRKTKIIEMMPEFQKSSVRIKNPTRVEEIICGLIKGGAA :::::::::::::::::::::::::::::: NP_001 MPEFQKSSVRIKNPTRVEEIICGLIKGGAA 10 20 30 90 100 110 120 130 140 pF1KE0 KLQIITDFDMTLSRFSYKGKRCPTCHNIIDNCKLVTDECRKKLLQLKEKYYAIEVDPVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLQIITDFDMTLSRFSYKGKRCPTCHNIIDNCKLVTDECRKKLLQLKEKYYAIEVDPVLT 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE0 VEEKYPYMVEWYTKSHGLLVQQALPKAKLKEIVAESDVMLKEGYENFFDKLQQHSIPVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEEKYPYMVEWYTKSHGLLVQQALPKAKLKEIVAESDVMLKEGYENFFDKLQQHSIPVFI 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE0 FSAGIGDVLEEVIRQAGVYHPNVKVVSNFMDFDETGVLKGFKGELIHVFNKHDGALRNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSAGIGDVLEEVIRQAGVYHPNVKVVSNFMDFDETGVLKGFKGELIHVFNKHDGALRNTE 160 170 180 190 200 210 270 280 290 300 310 320 pF1KE0 YFNQLKDNSNIILLGDSQGDLRMADGVANVEHILKIGYLNDRVDELLEKYMDSYDIVLVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YFNQLKDNSNIILLGDSQGDLRMADGVANVEHILKIGYLNDRVDELLEKYMDSYDIVLVQ 220 230 240 250 260 270 330 pF1KE0 DESLEVANSILQKIL ::::::::::::::: NP_001 DESLEVANSILQKIL 280 336 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 09:39:15 2016 done: Thu Nov 3 09:39:16 2016 Total Scan time: 7.200 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]