FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0432, 406 aa 1>>>pF1KE0432 406 - 406 aa - 406 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7775+/-0.000329; mu= 20.2502+/- 0.021 mean_var=59.3555+/-11.799, 0's: 0 Z-trim(114.2): 31 B-trim: 0 in 0/53 Lambda= 0.166473 statistics sampled from 23830 (23859) to 23830 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.28), width: 16 Scan time: 8.700 The best scores are: opt bits E(85289) NP_001316323 (OMIM: 611753) vacuole membrane prote ( 406) 2711 659.3 4.6e-189 NP_112200 (OMIM: 611753) vacuole membrane protein ( 406) 2711 659.3 4.6e-189 NP_001316324 (OMIM: 611753) vacuole membrane prote ( 419) 2170 529.4 6.2e-150 NP_001316328 (OMIM: 611753) vacuole membrane prote ( 309) 2044 499.1 6.2e-141 NP_001316325 (OMIM: 611753) vacuole membrane prote ( 369) 1823 446.0 6.8e-125 NP_001316329 (OMIM: 611753) vacuole membrane prote ( 272) 1801 440.7 2.1e-123 NP_001316327 (OMIM: 611753) vacuole membrane prote ( 322) 1503 369.2 8.3e-102 NP_001316331 (OMIM: 611753) vacuole membrane prote ( 214) 1431 351.7 9.7e-97 NP_001316330 (OMIM: 611753) vacuole membrane prote ( 253) 1409 346.5 4.3e-95 NP_001316326 (OMIM: 611753) vacuole membrane prote ( 350) 1409 346.6 5.6e-95 >>NP_001316323 (OMIM: 611753) vacuole membrane protein 1 (406 aa) initn: 2711 init1: 2711 opt: 2711 Z-score: 3515.2 bits: 659.3 E(85289): 4.6e-189 Smith-Waterman score: 2711; 99.8% identity (99.8% similar) in 406 aa overlap (1-406:1-406) 10 20 30 40 50 60 pF1KE0 MAENGKNCDQRRVAMNKEHHNGNFTDPSSVNEKKRREREERQNIVLWRQPLITLQYFSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAENGKNCDQRRVAMNKEHHNGNFTDPSSVNEKKRREREERQNIVLWRQPLITLQYFSLE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ILVILKEWTSKLWHRQSIVVSFLLLLAVLIATYYVEGVHQQYVQRIEKQFLLYAYWIGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILVILKEWTSKLWHRQSIVVSFLLLLAVLIATYYVEGVHQQYVQRIEKQFLLYAYWIGLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ILSSVGLGTGLHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTIFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : NP_001 ILSSVGLGTGLHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 ASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 MHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG 310 320 330 340 350 360 370 380 390 400 pF1KE0 ENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK :::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK 370 380 390 400 >>NP_112200 (OMIM: 611753) vacuole membrane protein 1 is (406 aa) initn: 2711 init1: 2711 opt: 2711 Z-score: 3515.2 bits: 659.3 E(85289): 4.6e-189 Smith-Waterman score: 2711; 99.8% identity (99.8% similar) in 406 aa overlap (1-406:1-406) 10 20 30 40 50 60 pF1KE0 MAENGKNCDQRRVAMNKEHHNGNFTDPSSVNEKKRREREERQNIVLWRQPLITLQYFSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 MAENGKNCDQRRVAMNKEHHNGNFTDPSSVNEKKRREREERQNIVLWRQPLITLQYFSLE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ILVILKEWTSKLWHRQSIVVSFLLLLAVLIATYYVEGVHQQYVQRIEKQFLLYAYWIGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 ILVILKEWTSKLWHRQSIVVSFLLLLAVLIATYYVEGVHQQYVQRIEKQFLLYAYWIGLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ILSSVGLGTGLHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTIFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : NP_112 ILSSVGLGTGLHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 WSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 ASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 ASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 MHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 MHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG 310 320 330 340 350 360 370 380 390 400 pF1KE0 ENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK :::::::::::::::::::::::::::::::::::::::::::::: NP_112 ENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK 370 380 390 400 >>NP_001316324 (OMIM: 611753) vacuole membrane protein 1 (419 aa) initn: 2168 init1: 2168 opt: 2170 Z-score: 2812.8 bits: 529.4 E(85289): 6.2e-150 Smith-Waterman score: 2675; 96.7% identity (96.7% similar) in 419 aa overlap (1-406:1-419) 10 20 30 40 50 60 pF1KE0 MAENGKNCDQRRVAMNKEHHNGNFTDPSSVNEKKRREREERQNIVLWRQPLITLQYFSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAENGKNCDQRRVAMNKEHHNGNFTDPSSVNEKKRREREERQNIVLWRQPLITLQYFSLE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ILVILKEWTSKLWHRQSIVVSFLLLLAVLIATYYVEGVHQQYVQRIEKQFLLYAYWIGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILVILKEWTSKLWHRQSIVVSFLLLLAVLIATYYVEGVHQQYVQRIEKQFLLYAYWIGLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ILSSVGLGTGLHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTIFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : NP_001 ILSSVGLGTGLHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 WSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 ASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIK 250 260 270 280 290 300 310 320 330 340 pF1KE0 MHIQKIFVIITFSKHIVEQMVAFIG-------------AVPGIGPSLQKPFQEYLEAQRQ ::::::::::::::::::::::::: :::::::::::::::::::::: NP_001 MHIQKIFVIITFSKHIVEQMVAFIGLEDNGALQPPPPSAVPGIGPSLQKPFQEYLEAQRQ 310 320 330 340 350 360 350 360 370 380 390 400 pF1KE0 KLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK 370 380 390 400 410 >>NP_001316328 (OMIM: 611753) vacuole membrane protein 1 (309 aa) initn: 2044 init1: 2044 opt: 2044 Z-score: 2651.2 bits: 499.1 E(85289): 6.2e-141 Smith-Waterman score: 2044; 99.3% identity (99.7% similar) in 306 aa overlap (101-406:4-309) 80 90 100 110 120 130 pF1KE0 KLWHRQSIVVSFLLLLAVLIATYYVEGVHQQYVQRIEKQFLLYAYWIGLGILSSVGLGTG .::::::::::::::::::::::::::::: NP_001 MDLKYVQRIEKQFLLYAYWIGLGILSSVGLGTG 10 20 30 140 150 160 170 180 190 pF1KE0 LHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTIFLWSIISKVRIE :::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::: NP_001 LHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIE 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE0 ACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQK 100 110 120 130 140 150 260 270 280 290 300 310 pF1KE0 LVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVII 160 170 180 190 200 210 320 330 340 350 360 370 pF1KE0 TFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEK 220 230 240 250 260 270 380 390 400 pF1KE0 LVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK :::::::::::::::::::::::::::::::::::: NP_001 LVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK 280 290 300 >>NP_001316325 (OMIM: 611753) vacuole membrane protein 1 (369 aa) initn: 2456 init1: 1801 opt: 1823 Z-score: 2363.2 bits: 446.0 E(85289): 6.8e-125 Smith-Waterman score: 2386; 90.6% identity (90.6% similar) in 406 aa overlap (1-406:1-369) 10 20 30 40 50 60 pF1KE0 MAENGKNCDQRRVAMNKEHHNGNFTDPSSVNEKKRREREERQNIVLWRQPLITLQYFSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAENGKNCDQRRVAMNKEHHNGNFTDPSSVNEKKRREREERQNIVLWRQPLITLQYFSLE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ILVILKEWTSKLWHRQSIVVSFLLLLAVLIATYYVEGVHQQYVQRIEKQFLLYAYWIGLG ::::::::::::::::::::::::::::::::::::::::: NP_001 ILVILKEWTSKLWHRQSIVVSFLLLLAVLIATYYVEGVHQQ------------------- 70 80 90 100 130 140 150 160 170 180 pF1KE0 ILSSVGLGTGLHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTIFL :::::::::::::::::::::::::::::::::::::::: : NP_001 ------------------GPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISL 110 120 130 140 190 200 210 220 230 240 pF1KE0 WSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDF 150 160 170 180 190 200 250 260 270 280 290 300 pF1KE0 ASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIK 210 220 230 240 250 260 310 320 330 340 350 360 pF1KE0 MHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG 270 280 290 300 310 320 370 380 390 400 pF1KE0 ENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK :::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK 330 340 350 360 >>NP_001316329 (OMIM: 611753) vacuole membrane protein 1 (272 aa) initn: 1801 init1: 1801 opt: 1801 Z-score: 2336.6 bits: 440.7 E(85289): 2.1e-123 Smith-Waterman score: 1801; 99.6% identity (99.6% similar) in 268 aa overlap (139-406:5-272) 110 120 130 140 150 160 pF1KE0 QFLLYAYWIGLGILSSVGLGTGLHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIIC :::::::::::::::::::::::::::::: NP_001 MDLKGPHIASVTLAAYECNSVNFPEPPYPDQIIC 10 20 30 170 180 190 200 210 220 pF1KE0 PDEEGTEGTIFLWSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFE :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PDEEGTEGTISLWSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFE 40 50 60 70 80 90 230 240 250 260 270 280 pF1KE0 EMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTF 100 110 120 130 140 150 290 300 310 320 330 340 pF1KE0 FGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQK 160 170 180 190 200 210 350 360 370 380 390 400 pF1KE0 LHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK 220 230 240 250 260 270 >>NP_001316327 (OMIM: 611753) vacuole membrane protein 1 (322 aa) initn: 1501 init1: 1501 opt: 1503 Z-score: 1948.7 bits: 369.2 E(85289): 8.3e-102 Smith-Waterman score: 2008; 95.3% identity (95.6% similar) in 319 aa overlap (101-406:4-322) 80 90 100 110 120 130 pF1KE0 KLWHRQSIVVSFLLLLAVLIATYYVEGVHQQYVQRIEKQFLLYAYWIGLGILSSVGLGTG .::::::::::::::::::::::::::::: NP_001 MDLKYVQRIEKQFLLYAYWIGLGILSSVGLGTG 10 20 30 140 150 160 170 180 190 pF1KE0 LHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTIFLWSIISKVRIE :::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::: NP_001 LHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIE 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE0 ACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQK 100 110 120 130 140 150 260 270 280 290 300 310 pF1KE0 LVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVII 160 170 180 190 200 210 320 330 340 350 pF1KE0 TFSKHIVEQMVAFIG-------------AVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGT ::::::::::::::: :::::::::::::::::::::::::::::::: NP_001 TFSKHIVEQMVAFIGLEDNGALQPPPPSAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGT 220 230 240 250 260 270 360 370 380 390 400 pF1KE0 PQGENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQGENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK 280 290 300 310 320 >>NP_001316331 (OMIM: 611753) vacuole membrane protein 1 (214 aa) initn: 1431 init1: 1431 opt: 1431 Z-score: 1857.8 bits: 351.7 E(85289): 9.7e-97 Smith-Waterman score: 1431; 100.0% identity (100.0% similar) in 214 aa overlap (193-406:1-214) 170 180 190 200 210 220 pF1KE0 PDQIICPDEEGTEGTIFLWSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDE :::::::::::::::::::::::::::::: NP_001 MWGIGTAIGELPPYFMARAARLSGAEPDDE 10 20 30 230 240 250 260 270 280 pF1KE0 EYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFL 40 50 60 70 80 90 290 300 310 320 330 340 pF1KE0 VPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYL 100 110 120 130 140 150 350 360 370 380 390 400 pF1KE0 EAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSE 160 170 180 190 200 210 pF1KE0 EKTK :::: NP_001 EKTK >>NP_001316330 (OMIM: 611753) vacuole membrane protein 1 (253 aa) initn: 1409 init1: 1409 opt: 1409 Z-score: 1828.2 bits: 346.5 E(85289): 4.3e-95 Smith-Waterman score: 1530; 81.4% identity (81.7% similar) in 306 aa overlap (101-406:4-253) 80 90 100 110 120 130 pF1KE0 KLWHRQSIVVSFLLLLAVLIATYYVEGVHQQYVQRIEKQFLLYAYWIGLGILSSVGLGTG .::::::::::::::::::::::::::::: NP_001 MDLKYVQRIEKQFLLYAYWIGLGILSSVGLGTG 10 20 30 140 150 160 170 180 190 pF1KE0 LHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTIFLWSIISKVRIE ::::::::: NP_001 LHTFLLYLG--------------------------------------------------- 40 200 210 220 230 240 250 pF1KE0 ACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQK ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -----IGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQK 50 60 70 80 90 260 270 280 290 300 310 pF1KE0 LVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVII 100 110 120 130 140 150 320 330 340 350 360 370 pF1KE0 TFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEK 160 170 180 190 200 210 380 390 400 pF1KE0 LVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK :::::::::::::::::::::::::::::::::::: NP_001 LVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK 220 230 240 250 >>NP_001316326 (OMIM: 611753) vacuole membrane protein 1 (350 aa) initn: 1409 init1: 1409 opt: 1409 Z-score: 1826.2 bits: 346.6 E(85289): 5.6e-95 Smith-Waterman score: 2197; 86.2% identity (86.2% similar) in 406 aa overlap (1-406:1-350) 10 20 30 40 50 60 pF1KE0 MAENGKNCDQRRVAMNKEHHNGNFTDPSSVNEKKRREREERQNIVLWRQPLITLQYFSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAENGKNCDQRRVAMNKEHHNGNFTDPSSVNEKKRREREERQNIVLWRQPLITLQYFSLE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ILVILKEWTSKLWHRQSIVVSFLLLLAVLIATYYVEGVHQQYVQRIEKQFLLYAYWIGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILVILKEWTSKLWHRQSIVVSFLLLLAVLIATYYVEGVHQQYVQRIEKQFLLYAYWIGLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ILSSVGLGTGLHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTIFL ::::::::::::::::::: NP_001 ILSSVGLGTGLHTFLLYLG----------------------------------------- 130 190 200 210 220 230 240 pF1KE0 WSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDF ::::::::::::::::::::::::::::::::::::::::::::: NP_001 ---------------IGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDF 140 150 160 170 180 250 260 270 280 290 300 pF1KE0 ASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIK 190 200 210 220 230 240 310 320 330 340 350 360 pF1KE0 MHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG 250 260 270 280 290 300 370 380 390 400 pF1KE0 ENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK :::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK 310 320 330 340 350 406 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 09:28:19 2016 done: Thu Nov 3 09:28:20 2016 Total Scan time: 8.700 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]