FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0434, 315 aa 1>>>pF1KE0434 315 - 315 aa - 315 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3937+/-0.00036; mu= 15.6882+/- 0.023 mean_var=67.4843+/-13.661, 0's: 0 Z-trim(114.9): 30 B-trim: 1545 in 2/51 Lambda= 0.156125 statistics sampled from 24946 (24963) to 24946 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.293), width: 16 Scan time: 6.780 The best scores are: opt bits E(85289) NP_078942 (OMIM: 148600,614888) alpha- and gamma-a ( 315) 2046 469.5 3.9e-132 NP_001258815 (OMIM: 148600,614888) alpha- and gamm ( 206) 1345 311.5 9.2e-85 NP_001258814 (OMIM: 148600,614888) alpha- and gamm ( 206) 1345 311.5 9.2e-85 XP_011520322 (OMIM: 148600,614888) PREDICTED: alph ( 206) 1345 311.5 9.2e-85 >>NP_078942 (OMIM: 148600,614888) alpha- and gamma-adapt (315 aa) initn: 2046 init1: 2046 opt: 2046 Z-score: 2493.3 bits: 469.5 E(85289): 3.9e-132 Smith-Waterman score: 2046; 97.8% identity (98.7% similar) in 315 aa overlap (1-315:1-315) 10 20 30 40 50 60 pF1KE0 MAAGVPCALVTSCSSVFSGDQLVQHTLGTEDLIAEVTSNDAVRFYPWTIDNKYYSADINL ::::::::::::::::::::::::: :::::::.:::::::::::::::::::::::::: NP_078 MAAGVPCALVTSCSSVFSGDQLVQHILGTEDLIVEVTSNDAVRFYPWTIDNKYYSADINL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CVVPNKFLVTAEIAESVQAFVVYFDSTRKSGLDSVSSWLPLAKAWLPEVMILVCDRVSED :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: NP_078 CVVPNKFLVTAEIAESVQAFVVYFDSTQKSGLDSVSSWLPLAKAWLPEVMILVCDRVSED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GINRQKAQEWSLKHGFELVELSPEELPEEDDDFPESTGVKRIVQALNANVWSNVVMKNDR :::::::::: .:::::::::::::::::::::::::::::::::::::::::::::::: NP_078 GINRQKAQEWCIKHGFELVELSPEELPEEDDDFPESTGVKRIVQALNANVWSNVVMKNDR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 NQGFSLLNSLTGTNHSIGSADPCHPEQPHLPAADSTESLSDHRGGASNTTDAQVDSIVDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 NQGFSLLNSLTGTNHSIGSADPCHPEQPHLPAADSTESLSDHRGGASNTTDAQVDSIVDP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 MLDLDIQELASLTTGGGDVENFERPFSKLKEMKDKAATLPHEQRKVHAEKVAKAFWMAIG :::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::: NP_078 MLDLDIQELASLTTGGGDVENFERLFSKLKEMKDKAATLPHEQRKVHAEKVAKAFWMAIG 250 260 270 280 290 300 310 pF1KE0 GDRDEIEGLSSDGEH :::::::::::: :: NP_078 GDRDEIEGLSSDEEH 310 >>NP_001258815 (OMIM: 148600,614888) alpha- and gamma-ad (206 aa) initn: 1345 init1: 1345 opt: 1345 Z-score: 1642.8 bits: 311.5 E(85289): 9.2e-85 Smith-Waterman score: 1345; 98.1% identity (98.5% similar) in 206 aa overlap (110-315:1-206) 80 90 100 110 120 130 pF1KE0 FVVYFDSTRKSGLDSVSSWLPLAKAWLPEVMILVCDRVSEDGINRQKAQEWSLKHGFELV ::::::::::::::::::::: .::::::: NP_001 MILVCDRVSEDGINRQKAQEWCIKHGFELV 10 20 30 140 150 160 170 180 190 pF1KE0 ELSPEELPEEDDDFPESTGVKRIVQALNANVWSNVVMKNDRNQGFSLLNSLTGTNHSIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELSPEELPEEDDDFPESTGVKRIVQALNANVWSNVVMKNDRNQGFSLLNSLTGTNHSIGS 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE0 ADPCHPEQPHLPAADSTESLSDHRGGASNTTDAQVDSIVDPMLDLDIQELASLTTGGGDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADPCHPEQPHLPAADSTESLSDHRGGASNTTDAQVDSIVDPMLDLDIQELASLTTGGGDV 100 110 120 130 140 150 260 270 280 290 300 310 pF1KE0 ENFERPFSKLKEMKDKAATLPHEQRKVHAEKVAKAFWMAIGGDRDEIEGLSSDGEH ::::: ::::::::::::::::::::::::::::::::::::::::::::::: :: NP_001 ENFERLFSKLKEMKDKAATLPHEQRKVHAEKVAKAFWMAIGGDRDEIEGLSSDEEH 160 170 180 190 200 >>NP_001258814 (OMIM: 148600,614888) alpha- and gamma-ad (206 aa) initn: 1345 init1: 1345 opt: 1345 Z-score: 1642.8 bits: 311.5 E(85289): 9.2e-85 Smith-Waterman score: 1345; 98.1% identity (98.5% similar) in 206 aa overlap (110-315:1-206) 80 90 100 110 120 130 pF1KE0 FVVYFDSTRKSGLDSVSSWLPLAKAWLPEVMILVCDRVSEDGINRQKAQEWSLKHGFELV ::::::::::::::::::::: .::::::: NP_001 MILVCDRVSEDGINRQKAQEWCIKHGFELV 10 20 30 140 150 160 170 180 190 pF1KE0 ELSPEELPEEDDDFPESTGVKRIVQALNANVWSNVVMKNDRNQGFSLLNSLTGTNHSIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELSPEELPEEDDDFPESTGVKRIVQALNANVWSNVVMKNDRNQGFSLLNSLTGTNHSIGS 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE0 ADPCHPEQPHLPAADSTESLSDHRGGASNTTDAQVDSIVDPMLDLDIQELASLTTGGGDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADPCHPEQPHLPAADSTESLSDHRGGASNTTDAQVDSIVDPMLDLDIQELASLTTGGGDV 100 110 120 130 140 150 260 270 280 290 300 310 pF1KE0 ENFERPFSKLKEMKDKAATLPHEQRKVHAEKVAKAFWMAIGGDRDEIEGLSSDGEH ::::: ::::::::::::::::::::::::::::::::::::::::::::::: :: NP_001 ENFERLFSKLKEMKDKAATLPHEQRKVHAEKVAKAFWMAIGGDRDEIEGLSSDEEH 160 170 180 190 200 >>XP_011520322 (OMIM: 148600,614888) PREDICTED: alpha- a (206 aa) initn: 1345 init1: 1345 opt: 1345 Z-score: 1642.8 bits: 311.5 E(85289): 9.2e-85 Smith-Waterman score: 1345; 98.1% identity (98.5% similar) in 206 aa overlap (110-315:1-206) 80 90 100 110 120 130 pF1KE0 FVVYFDSTRKSGLDSVSSWLPLAKAWLPEVMILVCDRVSEDGINRQKAQEWSLKHGFELV ::::::::::::::::::::: .::::::: XP_011 MILVCDRVSEDGINRQKAQEWCIKHGFELV 10 20 30 140 150 160 170 180 190 pF1KE0 ELSPEELPEEDDDFPESTGVKRIVQALNANVWSNVVMKNDRNQGFSLLNSLTGTNHSIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELSPEELPEEDDDFPESTGVKRIVQALNANVWSNVVMKNDRNQGFSLLNSLTGTNHSIGS 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE0 ADPCHPEQPHLPAADSTESLSDHRGGASNTTDAQVDSIVDPMLDLDIQELASLTTGGGDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADPCHPEQPHLPAADSTESLSDHRGGASNTTDAQVDSIVDPMLDLDIQELASLTTGGGDV 100 110 120 130 140 150 260 270 280 290 300 310 pF1KE0 ENFERPFSKLKEMKDKAATLPHEQRKVHAEKVAKAFWMAIGGDRDEIEGLSSDGEH ::::: ::::::::::::::::::::::::::::::::::::::::::::::: :: XP_011 ENFERLFSKLKEMKDKAATLPHEQRKVHAEKVAKAFWMAIGGDRDEIEGLSSDEEH 160 170 180 190 200 315 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 09:21:09 2016 done: Thu Nov 3 09:21:10 2016 Total Scan time: 6.780 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]